Improvement of multi-digital multiplicating devices structures in different theoretical and numerical bases

2021 ◽  
Vol 3 (1) ◽  
pp. 7-19
Author(s):  
N Vozna ◽  
◽  
A Davletova ◽  
Ya Nykolaychuk ◽  
V Gryga

The article proposes methods for improving the structures of multi-bit multipliers, which are characterized by increased speed, reduced structural complexity of the device and reduced structural complexity of inputs and outputs depending on the bit multipliers (512-2048 bits), respectively (1024- 4096) times, compared with known multipliers based on classic single-digit full adders. Optimization of structures of multi-bit multipliers is offered. Comparative estimates of structural, functional and relative functional and structural complexities of their circuit implementations are given. The use of optimized circuit solutions of multipliers allows to significantly improve the system characteristics of complex computing devices with a large number of such components in the crystals of microelectronic technologies.

Author(s):  
Natalia Vozna ◽  
Yaroslav Nykolaychuk ◽  
Alina Davletova

The article proposes methods for improving the structures of matrix multipliers of multi-digit numbers. Advanced single-bit total adders with paraphrase switched inputs and paraphrase outputs are used, intended as components of high-speed matrix multipliers. Based on the use of such single-bit adders, the structures of matrix multipliers are proposed, characterized by 2 times increased speed, 5 times reduced structural complexity compared to known multipliers based on classical single-bit adders. Optimization of structures of multi-bit matrix multipliers is offered. Comparative estimates of structural and temporal complexities of their circuit implementations depending on the bit size of multiplied binary numbers are given. The use of optimized circuit solutions of matrix multipliers can significantly improve the system characteristics of complex computing devices with many such components in the crystals of microelectronic technologies.


Author(s):  
M. Boublik ◽  
G. Thornton ◽  
G. Oostergetel ◽  
J.F. Hainfeld ◽  
J.S. Wall

Understanding the structural complexity of ribosomes and their role in protein synthesis requires knowledge of the conformation of their components - rRNAs and proteins. Application of dedicated scanning transmission electron microscope (STEM), electrical discharge of the support carbon film in an atmosphere of pure nitrogen, and determination of the molecular weight of individual rRNAs enabled us to obtain high resolution electron microscopic images of unstained freeze-dried rRNA molecules from BHK cells in a form suitable for evaluation of their 3-D structure. Preliminary values for the molecular weight of 28S RNA from the large and 18S RNA from the small ribosomal subunits as obtained by mass measurement were 1.84 x 106 and 0.97 x 106, respectively. Conformation of rRNAs consists, in general, of alternating segments of intramolecular hairpin stems and single stranded loops in a proportion which depends on their ionic environment, the Mg++ concentration in particular. Molecules of 28S RNA (Fig. 1) and 18S RNA (not shown) obtained by freeze-drying from a solution of 60 mM NH+4 acetate and 2 mM Mg++ acetate, pH 7, appear as partially unfolded coils with compact cores suggesting a high degree of ordered secondary structure.


Author(s):  
D. Chrétien ◽  
D. Job ◽  
R.H. Wade

Microtubules are filamentary structures found in the cytoplasm of eukaryotic cells, where, together with actin and intermediate filaments, they form the components of the cytoskeleton. They have many functions and show various levels of structural complexity as witnessed by the singlet, doublet and triplet structures involved in the architecture of centrioles, basal bodies, cilia and flagella. The accepted microtubule model consists of a 25 nm diameter hollow tube with a wall made up of 13 paraxial protofilaments (pf). Each pf is a string of aligned tubulin dimers. Some results have suggested that the pfs follow a superhelix. To understand how microtubules function in the cell an accurate model of the surface lattice is one of the requirements. For example the 9x2 architecture of the axoneme will depend on the organisation of its component microtubules. We should also note that microtubules with different numbers of pfs have been observed in thin sections of cellular and of in-vitro material. An outstanding question is how does the surface lattice adjust to these different pf numbers?We have been using cryo-electron microscopy of frozen-hydrated samples to study in-vitro assembled microtubules. The experimental conditions are described in detail in this reference. The results obtained in conjunction with thin sections of similar specimens and with axoneme outer doublet fragments have already allowed us to characterise the image contrast of 13, 14 and 15 pf microtubules on the basis of the measured image widths, of the the image contrast symmetry and of the amplitude and phase behaviour along the equator in the computed Fourier transforms. The contrast variations along individual microtubule images can be interpreted in terms of the geometry of the microtubule surface lattice. We can extend these results and make some reasonable predictions about the probable surface lattices in the case of other pf numbers, see Table 1. Figure 1 shows observed images with which these predictions can be compared.


1988 ◽  
Vol 19 (1) ◽  
pp. 5-16 ◽  
Author(s):  
Karen E. Pollock ◽  
Richard G. Schwartz

The relationship between syllabic structure and segmental development was examined longitudinally in a child with a severe phonological disorder. Six speech samples were collected over a 4-year period (3:5 to 7:3). Analyses revealed gradual increases in the complexity and diversity of the syllable structures produced, and positional preferences for sounds within these forms. With a strong preference for [d] and [n] at the beginning of syllables, other consonants appeared first at the end of syllables. Implications for clinical management of phonological disorders include the need to consider both structural position and structural complexity in assessing segmental skills and in choosing target words for intervention.


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