scholarly journals FORMULATION ANDEVALUATION OF TRANSDERMAL DRUG DELIVERY OF TORASEMIDE

Author(s):  
Sanjay Kumar Yadav ◽  
Ravikant Gupta ◽  
S M Malipatil ◽  
S K Gupta

A skin patch uses a special membrane to control the rate at which the liquid drug contained in the reservoir within the patch can pass through the skin and into the bloodstream. The basic components of any transdermal delivery system include the drug(s) dissolved or dispersed in a reservoir or inert polymer matrix; an outer backing film of paper, plastic, or foil; and a pressure-sensitive adhesive that anchors the patch to the skin. The adhesive is covered by a release liner, which needs to be peeled off before applying the patch to the skin. Drugs administered via skin patches include scopolamine, nicotine, estrogen, nitroglycerin, and lidocaine. Non-medicated patch markets include thermal and cold patches, nutrient patches, skin care patches (a category that consists of two major sub-categories-therapeutic and cosmetic), aroma patches, weight loss patches and patches that measure sunlight exposure.

2013 ◽  
Vol 6 (5) ◽  
pp. 573-578
Author(s):  
Chintankumar Jamanbhai Tank ◽  
Gourishankar Kalyanappa Kapse ◽  
Jayrajsinh Indrajitsinh Sarvaiya

2021 ◽  
Vol 12 (2) ◽  
pp. 1-4
Author(s):  
Syeda Jabeen Unnisa ◽  
Swarupa Arvapalli ◽  
B Karunakar ◽  
PS Rishika Reddy ◽  
A Vaishnavi ◽  
...  

Transdermal administration of drug is generally limited by the barrier function of the skin vascular system are one of the most controversial method for transdermal delivery of active substance. transdermal drug delivery system is designed to deliver biological active agents through the skin, principally by diffusion for local internal if not systemic effects. The transdermal delivery system was relaunched after the discovery of elastic vesicles like transfersome, ethosome, cubosome, phytosome etc. Transfersomes are a form of elastic or deformable vesicle, which were introduced in the early 1990s. Elasticity is generated by incorporation of edge activator in lipid bilayer structure. Drug absorbed and distributed into organs and tissue and eliminated from the body it must pass through one or more biological membranes at various locations such movement of drug across the membrane is called as drug transport for the drug delivery to cross the body it should pass through the membrane barrier. This concept of drug delivery system was designed in attempt to concentrate the amount of drug in the remaining drug; therefore, the phospholipid-based carrier system is of considerable interest in the era.


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