scholarly journals Synerisis and Cycling Test the Sendok Leaf Extract Gel (Plantago Mayor L.) with Optimization of Variations of Gelling Agent Carbomer 940 Concentration

Author(s):  
A L Yusuf ◽  
D Nugraha

The purpose of this study was to determine the effect of the concentration of the gelling agent Carbomer 940 on the gel of daun Leaf Extract (Plantago major L.). The method used is the experimental method. The extraction method used is maceration with 96% alcohol. The design in this study is the manufacture of a gel formulation of sendok Leaf extract (Plantago major L.) with the concentration of the gelling agent Carbomer 940 and the syneresis test. Syneresis test results show that all formulas do not occur syneresis. The results of the cycling test showed that the sendok Leaf (Plantago major L.) extract gel was not affected by storage temperature. The conclusion of this study shows the effect of variations in the concentration of the gelling agent Carbomer 940 on the quality of gel.

2017 ◽  
Vol 1 (1) ◽  
pp. 94
Author(s):  
Husnul Warnida ◽  
Yullia Sukawaty ◽  
Mega Mega

awang Tiwai has an antibacterial activity toward some microorganisms e.g. Staphylococcus epidermidis dan Propionibacterium acne, two acne related bacteria. Bawang Tiwai extract 1% and 2% were formulated into gel (no oil content, because oil could make the acne worse) with carbomer 940 as gelling agent. Physical stability of bawang tiwai gel was evaluated included stability, organoleptic, pH, homogeneity, viscosity, consistency, spreading test, and activity toward Staphylococcus epidermidis.  The result showed that all formulas are stable after 7 days. The test results of antibacterial activity gel are 17,24 mm dan gel 19,75 mm to gel 1% dan 2% respectively.


Author(s):  
Rizki Putri Nur Laili ◽  
Farida Arinie Soelistianto Arinie Soelistianto ◽  
Nanak Zakaria ◽  
Nurul Hidayati

Tofu has the best quality vegetable protein because it has the most complete amino acid composition and is believed to have high digestibility (85% -98%). According to SNI 01-3142-1998 and SII No. 0270-1990 testing criteria for soy tofu based on smell, taste, color, appearance, or texture. Tofu soybeans are prone to physical or texture damage due to factors such as inappropriate pH levels and insufficient storage which results in damaged tofu. Therefore in this study, it is proposed to determine the elasticity of soy tofu with the parameters tested are the pH level in the manufacture of soy tofu, the storage temperature, and the capacitance value to see how thick the tofu is with a capacitive sensor using the capacitor principle. Where the parallel plate capacitor is a capacitor consisting of two parallel metal plates. The test results of all sensors are sent to the database and will be displayed on the page on the Android application which will provide real-time sensor output information to the user. Based on the results of testing on this system using a pH sensor, the pH value is around 3-4 which indicates that the pH level used is very good for use in tofu processing, at pH 4.56 with storage at 29 ° C the highest elastic capacitance value is 3.58.  In testing data delivery, the throughput value is 4336,217 b / s and the smallest delay value is 0.017ms because the smaller the delay value, the better the quality of data transmission because there will be no delay in sending data.


2021 ◽  
Vol 4 (2) ◽  
pp. 98-103
Author(s):  
Nurista Dida Ayuningtyas ◽  
Agustina Putri Pitarisa Sudarsono ◽  
Anastasiya Sisca Yuswanti

Background : Lime leaves contain flavonoids, tannins, and saponins. This content is known to have activity as an antibacterial and protective of gums and teeth. Based on these activities, lime leaves can be developed as an active ingredient in gel toothpaste preparations. In the manufacture of gel toothpaste, the component that plays an important role is the gelling agent. Purpose: In this study, a variation of the gelling agent Carbomer 940 will be used to make a gel toothpaste with lime leaf extract. Methods: The independent variable used is Carbomer 940 with a variation of 3 formulas, namely 0.6%; 1.2%; and 1.8%. The evaluations carried out on gel toothpaste were organoleptic, homogeneity, pH, adhesion, spreadability and pH. Data analysis was carried out with SPSS software to see the differences between each formula. Results: The results showed that the formula 1-3 was homogeneous with a clear, homogeneous color, and a characteristic smell of menthol with a pH range of 5.85-7.49; spreading area 20.60-29.91 cm2, adhesion 6.01-35.1 seconds. The results of statistical tests with one-way ANOVA obtained a significant difference between each formula.  


2017 ◽  
Vol 5 (2) ◽  
pp. 75
Author(s):  
Via Fitria ◽  
Rafiki Fahrul Arifin ◽  
Nia Kurniasih

<p align="center"><strong>Abstrak</strong></p><p align="center"><strong> </strong></p><p>Masyarakat Indonesia mengenal dan memanfaatkan tanaman berkhasiat obat sebagai salah satu upaya dalam penanggulangan masalah kesehatan. Salah satu tanaman berkhasiat untuk menyembuhkan luka bakar adalah daun pohpohan (<em>Pilea trinervia </em>W.). Penelitian ini bertujuan menguji aktivitas gel ekstrak daun pohpohan (<em>Pilea trinervia W</em>.) terhadap penyembuhan luka bakar pada kelinci. Pembuatan gel dilakukan pada beberapa konsentrasi ekstrak daun pohpohan, yaitu 0,5, 1, dan 2%, Setelah dilakukan pembuatan gel, maka dilakukan evaluasi gel untuk mengetahui kualitas sediaan, meliputi uji organoleptis, homogenitas, uji pH, uji daya sebar, uji daya lekat, dan uji aktivitas luka bakar. Uji aktivitas luka bakar dilakukan pada 3 ekor kelinci jantan dengan 5 sisi perlakuan pada tiap kelinci, dan diinduksi dengan logam panas dengan alat uji Rafiky’sTool Pressure Test. Sebagai pembanding digunakan Bioplacenton®. Pemberian gel pada pengobatan luka bakar dilakukan 2 kali sehari. Parameter yang diukur adalah diameter luka bakar selama 10 hari. Data hasil uji aktivitas luka bakar diuji statistik menggunakan uji non parametric Kruskal-Wallis dan uji lanjut Mann Whitney. Hasil evaluasi gel menunjukkan bahwa gel yang mengandung ekstrak daun pohpohan konsentrasi 0,5, 1, dan 2% memenuhi persyaratan homogenitas, pH, daya penyebaran dan daya lekat. Hasil uji aktivitas luka bakar menunjukkan bahwa gel dengan konsentrasi ekstrak pohpohan 0,5, 1, dan 2% mampu menurunkan diameter luka bakar lebih cepat dibandingkan kontrol. Kelompok ekstrak daun pohpohan 2% memiliki aktivitas penyembuhan luka bakar paling cepat dan hampir sama dengan kontrol positif Bioplacenton®. Dapat disimpulkan bahwa gel yang mengandung ekstrak pohpohan mempunyai aktivitas menyembuhkan luka bakar.</p><p> </p><p><strong>Kata kunci:</strong>     Daun pohpohan (<em>Pilea trinervia</em> W.), Gel, Luka bakar</p><p> </p><p align="center"><strong><em>Wound healing activity of pohpohan </em></strong><strong>(<em>Pilea trinervia </em>W.) </strong><strong><em>extract gel on rabbit</em></strong></p><p align="center"><strong><em> </em></strong></p><p align="center"><strong><em>Abstract</em></strong></p><p align="center"><strong><em> </em></strong></p><p><em>Indonesian people recognize and utilize nutritious crops as one of the efforts in the prevention of health problems. One of the nutritious plants to heal burns is the leaves of pohpohan (Pilea trinervia W.). This study aims to test the activity of pohpohan leaf extract (Pilea trinervia W.) on the healing of burns in rabbits. Preparation of gel is done on some concentration of pohpohan leaf extract, that is 0,5, 1, and 2%. After gel making, gel evaluation is done to know the quality of preparation, including organoleptic test, homogeneity, pH test, spreading test, sticky, and burn activity test. Burning activity test was performed on 3 male rabbits with 5 treatment sides on each rabbit, and induced with hot metal by Rafiky'sTool Pressure Test. For comparison use Bioplacenton®. Gels on the treatment of burns done 2 times a day. Parameters measured were burn diameter for 10 days. Data on burn activity test results were tested statistically using non-parametric Kruskal-Wallis test and further test of Mann Whitney. The results of gel evaluation showed that the gel containing pohpohan leaves extract concentration of 0.5, 1, and 2% fulfilled the homogeneity, pH, dispersion and stickiness requirements. The result of burn activity test showed that gel with concentration of 0,5, 1, and 2% extract pohpohan able to reduce burn burn diameter faster than control. The 2% pohpohan leaf extract group has the fastest burn healing activity and almost equal to the positive control of Bioplacenton®. It can be concluded that gel containing pohpohan extract has activity to heal burns.</em></p><p><em> </em></p><p><strong><em>Keywords:</em></strong><em>  P</em><em>ohpohan (Pilea trinervia W.), Gel, Wound healing</em></p>


2019 ◽  
Vol 2 (1) ◽  
pp. 6-15
Author(s):  
Cucu Arum Dwi Cahya ◽  
Aminah Syarifuddin ◽  
Ahmad Syukur Syukur

Green mustard plants can be formulater into peel-off masks to moisturize the skin, because based on previous research green mustard leaves cointain flavonoids as antioxidants which can moisturize the skin. The purpose of this study was to find out green mustard leaves can be formulated into peel-off mask preparations and to find out the preparation and to find out the preparation off peel off mask with etanol extract of green mustard leaves can moisturize the skin. This study uses an experimental method. Green mustard leaves are extracted by maceration. In this study, a skin analyzer was usee as a mesure of skin moisture level after using peel off mask from a variety of dosage formulations which were divided into 5 preparations, blank (without mask, 3%,4%,5%), postive control (using peel off masks on the market). The Anova test results show a sig value of 0,000 or p<0,005 so it is concluded that the variabel has a difference. The conclusion of this study proves that the ethanol extract of green mustard leaves can be used as a peel-off mask for skin moisturizer, where the higher the concentration of mustard leaf extract, the higher the moisture vlue of the skin.


PHARMACON ◽  
2019 ◽  
Vol 8 (2) ◽  
pp. 261
Author(s):  
Meyla C. M. Pratasik ◽  
Paulina V. Y. Yamlean ◽  
Weny I Wiyono

ABSTRACT Sesewanua Leaves (Clerodendron squamatum Vahl.) have the potential to be made as skin care cosmetic preparations but must be in the right formulation to achieve the desired effect. The aim of this study was to determine the physical stability of a cream from Sesewanua leaf extract. This study used a experimental method by making ethanol extract of Sesewanua leaves with a concentration of 0.5% and physical stability test. Physical evaluation was carried out before and after cycling test through organoleptic observation, homogenety test, pH test, dispersion test, adhesion test, viscosity test, centrifugation test and cream type determination. The results of the physical evaluation showed that F1 without Sesewanua leaf extract and F2 with Sesewanua leaf extract creams met the requirements of physical stability, so can be concluded that Sesewanua leaf extract can be formulated into cream preparations with concentration of 0.5% which is physically stable before and after cycling test. Keywords: Sesewanua Leaves, Cream, Physical Stability  ABSTRAK Daun Sesewanua (Clerodendron squamatum Vahl.) berpotensi untuk dibuat sebagai sediaan kosmetik perawatan kulit namun harus dengan formulasi yang tepat agar mencapai efek yang diinginkan. Penelitian ini bertujuan untuk mengetahui stabilitas fisik sediaan krim ekstrak daun sesewanua. Penelitian ini menggunakan metode eksperimental dengan membuat krim ekstrak etanol daun Sesewanua dengan konsentrasi 0,5% dan uji stabilitas fisik. Evaluasi fisik dilakukan sebelum dan sesudah cycling test melalui pengamatan organoleptis, uji homogenitas, uji pH, uji daya sebar, uji daya lekat, uji viskositas, uji sentrifugasi dan penentuan tipe krim. Hasil evaluasi fisik menunjukkan krim F1 tanpa ekstrak daun Sesewanua dan F2 dengan ekstrak daun Sesewanua memenuhi persyaratan stabilitas fisik. Berdasarkan hasil penelitian dapat disimpulkan ekstrak daun sesewanua dapat diformulasi menjadi sediaan krim dengan konsentrasi 0,5% yang stabil secara fisik sebelum dan sesudah cycling test. Kata Kunci : Daun Sesewanua, Krim, Stabilitas Fisik


Author(s):  
Dhika Satriawan Fathoni ◽  
Ilham Fadhillah ◽  
Mujtahid Kaavessina

This research aims to study the effectiveness of betel leaf extract as a substitute for antibacterial active ingredients in hand sanitizer. Betel leaf extract is obtained by maceration of betel leaves for 3x24 hours in 70% alcohol solution. The alcohol content in the betel leaf extract from maceration was evaporated in the vacuum evaporator (T = 60<sup>o</sup>C) until the remaining extract volume was around 15%. This extract is used as an active antibacterial ingredient in making hand sanitizer gel. The basic chemicals of making gels such as carbomer (gelling agent), propylene glycol (stabilizer), glycerin, nipagin and triethanolamine / TEA (alkalizing agent) are mixed and stirred in distilled water (about 85 ml) with compositions of 0.3 g, 4 ml, 3 ml, 0.02 g and 0, 2 ml, respectively. The volume of extract added in the gel was varied 8, 10, and 12 ml. Finally, the volume of hand sanitizer was added distilled water to adjust its volume 100 ml. The effectiveness and quality of this hand sanitizer were analyzed its active compounds, gel acidity (pH), organoleptic, the inhibitory ability of bacterial growth, and gel dispersion. <em>Staphylococcus aureus</em> was chosen as the bacteria tested because it found in the hands.  The presence of saponin, tannins, and flavonoids is detected qualitatively in the product. The results showed that adding 12 ml extract of betel leaf (sample III) has the best performance in the studied range of extract concentration (8-12 ml).  Sample III has the acidity (pH) and the inhibitory zone about 5 and 9.78 mm<sup>2</sup>, respectively. This inhibitory area is higher than that of the commercial hand sanitizer, which has an area of 2.98 mm<sup>2</sup>. However, the spreadability of this hand sanitizer is slightly lower than that of the commercial one (about 167% and 180%). Organoleptic tests depict that this product is acceptable in the community because it does not irritate in use. This product is safer as hand sanitizer than the similar products that use alcohol as an active ingredient.


2020 ◽  
Vol 3 (2) ◽  
pp. 332
Author(s):  
Muhammad Bahrudin ◽  
Agata Iwan Candra ◽  
Sigit Winarto

Concrete is one of the construction materials that is widely used. Currently, variations in concrete are being studied. Galvalum waste has high tensile properties but is mild. Its lightweight properties are expected to reduce the weight of the concrete itself. The purpose of this study is to find out the value of strong press, absorption, weight type (E), degree of saturation (Sr), moisture content (Wc), and porosity of the addition of galvalume waste. The method used is a experimental method. Variations in galvalum waste substitution used are 50% and 100% of the aggregate weight is roughT the sample used in the form of a cylinder size of 15cm x 30 cm with the initial quality of fc' 18.67 Mpa. The results of the strong press test showed that the galvalum waste subtitution has not been able to exceed the initial quality of the plan. The highest test result was obtained at a percentage of 50% with a strong press score of FC' 17.94 Mpa. In the percentage, absorption test results are 0.010%, the weight of the type is 2325 kg / m3, the pore number is 0.00232%, the water content is 0.108%, and porosity is 0.00108%.Beton merupakan salah satu bahan konstruksi yang banyak dipergunakan. Saat ini, pengguanaan variasi pada beton sedang banyak diteliti. Limbah galvalum memiliki sifat tarik yang tinggi namun ringan. Sifatnya yang ringan diharapkan mampu mengurangi berat beton itu sendiri. Tujuan dari penelitian ini adalah untuk mengetahui nilai kuat tekan, absorpsi, berat jenis (Ɣ), angka pori (e),derajat kejenuhan (Sr), kadar air (Wc), dan porositas dari penambahan limbah galvalum. Metode yang digunakan merupakan metode eksperimen. Variasi pensubtitusi limbah galvalum yang digunakan yaitu 50% dan 100% dari berat agregat kasar. sampel yang digunakan berbentuk silinder ukuran 15cm x 30 cm dengan mutu awal fc’ 18.67 Mpa. Hasil uji kuat tekan menunjukkan bahwa subtitusi limbah galvalum belum mampu melebihi mutu awal rencana. Hasil uji tertinggi didapat pada prosentase 50% dengan nilai kuat tekan fc’ 17,94 Mpa. Pada prosentase tersebut, didapat hasil uji absropsi yaitu 0,010%,  berat jenis yaitu 2325 kg/m3, angka pori yaitu 0,00232%, kadar air yaitu 0,108% serta porositas yaitu 0,00108%. 


2021 ◽  
Vol 1 (2) ◽  
Author(s):  
Hikam Fuadi ◽  
Ida Agustini Saidi

Rosela flower (H. sabdariffa L.) is one of the plants that has many health benefits, which contain Vitamin C, Vitamin A, essential proteins, and 18 types of amino acids that aim to strengthen the body's immune system, treat diabetes, inhibit cancer cells and many more properties of this plant. Gelling agent commonly used to make jelly candy is gelatin, but in the application sometimes gelatin even makes the texture of jelly candy becomes very hard if the added concentration is not appropriate, besides the price of special gelatin food ( food grade) is still relatively expensive compared to other hydrocolloid materials. That's why it takes another gel shaper that can improve the quality of the texture of jelly candy and suppress the use of gelatin, one of which can be used seaweed (E. spinosum). The objective of this research was to find out the effect of various proportions of seaweed (E. spinosum) and gelatin on the characteristics of roselle jelly candy (H. sabdariffa L.). The method used is non-parametric statistical tests (Friedman test) with 10 levels of treatment and performed three times the test on each treatment. The treatment that will be done is a comparison of various proportions of seaweed: gelatin, namely PI (0: 8); P2 (0: 10); P3 (25:8); P4 (25:10); P5 (30:8); P6 (30:10); P7 (35:0); P8 (35:8); P9 (40:0) and P10 (40:8). The results showed there was a very noticeable difference in all the comparative treatment of seaweed and gelatin proportions against all test parameters. The best organoleptic test results showed color organoleptic test scores of 3.00 (neutral), organoleptic textures of 3.37 (neutral-like), organoleptic flavors of 3.40 (neutral-like) and organoleptic aromas of 3.00 (neutral).


2021 ◽  
Vol 2 (3) ◽  
pp. 192-195
Author(s):  
Anggraeni ◽  
Ristika Handarini ◽  
Deden Sudrajat ◽  
Burhanudin Malik ◽  
Viona Oktavia

Duck egg is known to have an unpleasant fishy odor which often becomes a factor reducing its acceptance in public.  This odor is resulted from lipid oxidation which can be avoided by using an antioxidant.  This study was aimed at assessing the effects of the inclusion of star gooseberry (Sauropus androgynus) dried leaf extract in ration on egg organoleptic quality of local duck.  The study was conducted in a completely randomized design with 4 treatments and 4 replicates.  Sensory test by 60 semi-trained panelists and hedonic quality and hedonic tests were conducted.  Data were subjected to a Kruskal-Wallis test.  Results showed that treatments gave significant effects (P <0.05) on aroma (hedonic), yolk color, and aroma (hedonic quality).  It was concluded that the inclusion of star gooseberry dried leaf extract by 1,5% in ration improved the quality of egg yolk color, egg aroma, and consumers’ preference.  A further study on the effects of DSGLE on meat quality and protein digestibility in ducks was recommended.


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