scholarly journals A Prioritized Research Agenda for Using the Harmonized Outcome Measures To Support Patient-Centered Outcomes Research in Depression

Author(s):  
Michelle B. Leavy ◽  
Anna Swenson ◽  
Richard Gliklich
2013 ◽  
Vol 32 (2) ◽  
pp. 393-400 ◽  
Author(s):  
Rachael Fleurence ◽  
Joe V. Selby ◽  
Kara Odom-Walker ◽  
Gail Hunt ◽  
David Meltzer ◽  
...  

2014 ◽  
Vol 28 (1) ◽  
pp. 101-104 ◽  
Author(s):  
Rita H. Pickler ◽  
Heather L. Tubbs-Cooley

2020 ◽  
Author(s):  
Michelle B. Leavy ◽  
Danielle Cooke ◽  
Sarah Hajjar ◽  
Erik Bikelman ◽  
Bailey Egan ◽  
...  

Background: Major depressive disorder is a common mental disorder. Many pressing questions regarding depression treatment and outcomes exist, and new, efficient research approaches are necessary to address them. The primary objective of this project is to demonstrate the feasibility and value of capturing the harmonized depression outcome measures in the clinical workflow and submitting these data to different registries. Secondary objectives include demonstrating the feasibility of using these data for patient-centered outcomes research and developing a toolkit to support registries interested in sharing data with external researchers. Methods: The harmonized outcome measures for depression were developed through a multi-stakeholder, consensus-based process supported by AHRQ. For this implementation effort, the PRIME Registry, sponsored by the American Board of Family Medicine, and PsychPRO, sponsored by the American Psychiatric Association, each recruited 10 pilot sites from existing registry sites, added the harmonized measures to the registry platform, and submitted the project for institutional review board review Results: The process of preparing each registry to calculate the harmonized measures produced three major findings. First, some clarifications were necessary to make the harmonized definitions operational. Second, some data necessary for the measures are not routinely captured in structured form (e.g., PHQ-9 item 9, adverse events, suicide ideation and behavior, and mortality data). Finally, capture of the PHQ-9 requires operational and technical modifications. The next phase of this project will focus collection of the baseline and follow-up PHQ-9s, as well as other supporting clinical documentation. In parallel to the data collection process, the project team will examine the feasibility of using natural language processing to extract information on PHQ-9 scores, adverse events, and suicidal behaviors from unstructured data. Conclusion: This pilot project represents the first practical implementation of the harmonized outcome measures for depression. Initial results indicate that it is feasible to calculate the measures within the two patient registries, although some challenges were encountered related to the harmonized definition specifications, the availability of the necessary data, and the clinical workflow for collecting the PHQ-9. The ongoing data collection period, combined with an evaluation of the utility of natural language processing for these measures, will produce more information about the practical challenges, value, and burden of using the harmonized measures in the primary care and mental health setting. These findings will be useful to inform future implementations of the harmonized depression outcome measures.


2018 ◽  
Vol 24 (6) ◽  
pp. 1111-1118 ◽  
Author(s):  
Linda J. Burns ◽  
Beatrice Abbetti ◽  
Stacie D. Arnold ◽  
Jeffrey Bender ◽  
Susan Doughtie ◽  
...  

2021 ◽  
pp. 1-3
Author(s):  
Erica Sood ◽  
Jeffrey P Jacobs ◽  
Bradley S Marino

Abstract Neurodevelopmental and psychosocial impairments negatively impact health-related quality of life for survivors with CHD and complicate the transition to independent adulthood. Risk for neurodevelopmental and psychosocial impairments is influenced by a complex interplay among genetic, foetal, surgical, perioperative, family, and social factors, requiring a multi-pronged approach to neuroprotection and intervention. To ensure future research can ultimately reduce the burden of CHD for individuals, families, and society, the most pressing issues in cardiac neurodevelopment requiring scientific investigation must be identified. Through funding from an R13 Grant from the National Heart, Lung, and Blood Institute of the National Institutes of Health of the United States of America, the Cardiac Neurodevelopmental Outcome Collaborative convened a two-day meeting of international experts in cardiac neurodevelopmental and psychosocial research, clinical care, and health disparities, including patient and family stakeholders, to define the cardiac neurodevelopmental and psychosocial outcomes research agenda for the next decade. Seven multidisciplinary working groups were formed to address key domains crucial to the advancement of cardiac neurodevelopmental and psychosocial outcomes research: 1) Foetal Brain Development and Neuroprotection, 2) Surgical/Perioperative Neuroprotection and Neurodevelopment, 3) Characterization of Neurodevelopmental and Psychological Outcomes, 4) Neurodevelopmental and Psychosocial Intervention, 5) Parent Mental Health and Family Functioning, 6) Neurodevelopmental Education, Outreach and Advocacy, and 7) Health Disparities and Neurodevelopmental Outcomes. Working groups identified significant gaps in knowledge and critical questions that must be answered to further knowledge, policy, care, and outcomes. The development of a research agenda in cardiac neurodevelopmental and psychosocial outcomes is critical for informing collaborative initiatives and allocation of funding for research to scientific inquiries of highest value to key stakeholders.


BMJ ◽  
2020 ◽  
pp. m4435
Author(s):  
Bridget Gaglio ◽  
Michelle Henton ◽  
Amanda Barbeau ◽  
Emily Evans ◽  
David Hickam ◽  
...  

2020 ◽  
pp. 106256
Author(s):  
Shannon M. Kearney ◽  
Kelly Williams ◽  
Cara Nikolajski ◽  
Margaret Park ◽  
Kevin L. Kraemer ◽  
...  

2021 ◽  
Vol 16 (3) ◽  
pp. S192
Author(s):  
V. Musigdilok ◽  
B. Creekmur ◽  
E. Rozema ◽  
M. Gould

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