Development of renal adenocarcinoma in a ferret with renal cortical cysts (Mustela putorius furo)

2021 ◽  
pp. 1-8
Author(s):  
Amanda D. Wong ◽  
Delphine Laniesse ◽  
Alex zur Linden ◽  
Ameet Singh ◽  
Leonardo Susta ◽  
...  
Keyword(s):  
Clinical Signs ◽  
Renal Cysts ◽  
Clinical Findings ◽  
Surgical Removal ◽  
Mustela Putorius ◽  
Initial Examination ◽  
Contralateral Kidney ◽  
Renal Adenocarcinoma ◽  
Contrast Enhanced Ct ◽  
Mustela Putorius Furo

Abstract CASE DESCRIPTION A 5.5-year-old 0.929-kg spayed female domestic ferret (Mustela putorius furo) underwent serial abdominal ultrasonographic and clinicopathologic examinations after multiple renal cysts were detected bilaterally during a routine examination. CLINICAL FINDINGS The ferret was apparently healthy at the start of the monitoring period and had no clinical signs for > 20 months. Four months after the initial examination, the largest cyst became increasingly mineralized; 17 months after detection, it had increased in size and become amorphous, and the ferret’s plasma BUN concentration was mildly high. Within 21 months after the first visit, a nodule was detectable, and hydronephrosis developed in the kidney with the largest cyst. Findings for fine-needle aspirates from the nodule were consistent with renal carcinoma. TREATMENT AND OUTCOME Contrast-enhanced CT revealed severe unilateral nephromegaly with no contrast uptake in the affected ureter. Following surgical removal of the affected kidney, histologic examination identified renal adenocarcinoma replacing the entire renal cortex and medulla. The ferret was euthanized postoperatively because of declining condition. On necropsy, metastasis to a mesenteric lymph node was identified; comorbidities included 2 other neoplasms and acute, severe injury of the contralateral kidney. CLINICAL RELEVANCE Neoplastic transformation of a renal cyst was suspected in the ferret of this report on the basis of observed ultrasonographic changes over time and extensive infiltration of the neoplasm throughout the affected kidney. Renal cysts are linked to renal neoplasia in other species, and the findings for this patient supported the need for periodic monitoring of renal cysts in ferrets.

Eosinophilic Gastroenteritis with Splendore-Hoeppli Material in the Ferret (Mustela putorius furo)

1992 ◽  
Vol 29 (1) ◽  
pp. 21-26 ◽  
Author(s):  
J. G. Fox ◽  
L. S. Palley ◽  
R. Rose
Keyword(s):  
Clinical Signs ◽  
Infectious Agent ◽  
Multiple Organ ◽  
Eosinophilic Gastroenteritis ◽  
Human Beings ◽  
Mesenteric Lymph Nodes ◽  
Mustela Putorius ◽  
Mesenteric Lymph ◽  
Small Intestinal ◽  
Mustela Putorius Furo

Eosinophilic gastroenteritis, focal or diffuse with eosinophilic infiltrations of the stomach or intestine, has been described in human beings, cats, dogs, and horses. In this paper, we describe infiltration of the gastrointestinal tract with eosinophils accompanied by a circulating eosinophilia in six ferrets ( Mustela putorius furo). Clinical signs included chronic weight loss, anorexia, and diarrhea. The small intestines from five ferrets had diffuse infiltrates of eosinophils. This resulted in focal or multifocal loss of the muscular tunic in three ferrets. Two of these ferrets also had eosinophilic gastritis. Eosinophilic granulomas with Splendore-Hoeppli material were present in mesenteric lymph nodes in four ferrets. Two ferrets had multiple organ involvement; one had eosinophilic granulomas in the liver, mesentery, and choroid plexus as well as moderate parapancreatic segmental arteritis with infiltration of eosinophils and mural thrombosis. The second ferret had, in addition to moderate diffuse gastric and small intestinal eosinophilic mucosal infiltrations, interstitial eosinophilic pulmonary infiltrates. Examination of all tissues failed to reveal an infectious agent.

scholarly journals Splenic Leiomyoma in Dog

2018 ◽  
Vol 6 (1) ◽  
pp. 8-12 ◽  
Author(s):  
Magdalena Magas ◽  
Katarzyna Szczepańska ◽  
Maurycy Jankowski ◽  
Dorota Bukowska ◽  
Paweł Antosik
Keyword(s):  
Clinical Case ◽  
Benign Tumor ◽  
Histopathological Examination ◽  
Smooth Muscles ◽  
Clinical Signs ◽  
Clinical Findings ◽  
Surgical Removal ◽  
Benign Lesions ◽  
X Ray ◽  
Tumor Lesion

AbstractLeiomyoma is a benign tumour, originating from smooth muscles cells. This tumor commonly involves the uterus, vagina, stomach, intestine, urinary bladder and other organs. Only a few cases of splenic leiomyoma in dogs have been reported in the available literature. Much more frequently malignant leiomyosarcoma was found. The aim of this study was to compile rare clinical case of splenic leiomyoma in dog, which developed with no clinical signs and no abnormalities in blood findings. A 14-year-old, spayed bitch was examined with ultrasonography, where lesions on the spleen were identified. Based on the clinical findings (blood test in norm, no metastases in X-ray examination) surgical removal of spleen was recommended. Two fragments of tumors were prepare for histopathological examination. The lesion was described as smooth muscle benign tumor, therefore a diagnosis of leiomyoma was made. About a year after splenectomy no signs of metastases were present in a ultrasound and X-ray examinations. This report indicates the necessity of taking the occurrence of benign lesions in the spleen into account. Splenectomy based on the presence of tumor lesion should be associated with histopathological examination to identify the nature of change. This clinical case, despite a marked morphological lesion shown during intraoperative examination, was benign with successful prognosis.

scholarly journals Case Report : Urolith Surgical Removal in a Green Iguana (Iguana iguana) (LAPORAN KASUS : BEDAH PENGELUARAN BATU KANTUNG KEMIH PADA SEEKOR IGUANA HIJAU (IGUANA IGUANA))

2018 ◽  
Vol 19 (1) ◽  
pp. 143 ◽  
Author(s):  
Puveanthan Nagappan Govendan ◽  
I Gusti Made Ananthawijaya ◽  
Anak Agung Gede Jayawarditha
Keyword(s):  
Case Report ◽  
Urinary Bladder ◽  
Clinical Signs ◽  
Clinical Findings ◽  
Surgical Removal ◽  
Healthy Animal ◽  
Iguana Iguana ◽  
Green Iguana ◽  
Radio Imaging ◽  
Urate Secretion

Two years old male Green Iguana (Iguana iguana) weighing 1.3 kilograms presented with a swelling mass in the abdomen. Clinical signs, palpation and radiography images indicated urolith in the urinary bladder. The mass was radiopaque and had a width of 37 mm and a length of 41 mm. Clinical findings, examination and radio-imaging confirmed urolithiasis in the urinary bladder. Coeliotomy and cystotomy were performed to remove the urolith. Two days after surgery, the iguana regained its appetite and normal urate secretion was observed. Prognosis is good when surgery is performed on a healthy animal.

Coronaviren als Ursache einer systemischen granulomatösen Entzündung bei einem Frettchen (Mustela putorius furo)

2009 ◽  
Vol 37 (01) ◽  
pp. 40-44
Author(s):  
C. Maresch ◽  
A. Bracke ◽  
D. Bröker ◽  
A. Kirchhoff ◽  
J. P. Teifke
Keyword(s):  
Sich Eine ◽  
Mustela Putorius ◽  
Granulomatöse Entzündung ◽  
Mustela Putorius Furo

Zusammenfassung Gegenstand: Ein 3 Jahre altes weibliches Frettchen (Mustela putorius furo) wurde mit vergrößerten Kopflymphknoten bei ungestörtem Allgemeinbefinden vorgestellt. Im weiteren Verlauf kam es zu einer syste-mischen Schwellung der Körperlymphknoten und zu einer Vergrößerung der Milz bei zunehmender Verschlechterung des Allgemeinbefindens. Material und Methoden: Nach klinischer und ultrasonographischer Untersuchung wurden Feinnadelaspirate von Milz und Lymphknoten gewonnen und zytologisch untersucht. Die Milz und ein geschwollener Kniekehllymphknoten wurden entnommen und histopathologisch sowie immunhistologisch auf Gruppe-1-Coronavirusantigen untersucht. Ergebnisse: Zytopathologisch war eine reaktive Hyperplasie der vergrößerten Milz und des Lymphknotens nachweisbar. Histopathologisch fanden sich eine herdförmige pyogranulomatöse Splenitis sowie eine granulomatöse Lymphadenitis. Coronavirusantigen konnte in Makrophagen von Milz und Lymphknoten nachgewiesen werden. Schlussfolgerung: Als Ursache für die granulomatöse Entzündung wird die systemische Coronavirusinfektion der Frettchen (FSCV) angesehen, die vermutlich durch einen mit dem enteralen Coronavirus der Frettchen (FECV) eng verwandten Erreger hervorgerufen wird.

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