scholarly journals Medication adherence and health-related quality of life among patients with chronic obstructive pulmonary disease

2018 ◽  
Vol 68 (1) ◽  
pp. 117-125 ◽  
Author(s):  
Nejc Horvat ◽  
Igor Locatelli ◽  
Mitja Kos ◽  
Ana Janežič
Keyword(s):  
Quality Of Life ◽  
Medication Adherence ◽  
Chronic Obstructive ◽  
Health Related Quality ◽  
Obstructive Pulmonary Disease ◽  
Related Quality ◽  
Health Related ◽  
St George's Respiratory Questionnaire ◽  
Lower Hrqol

Abstract This study evaluated medication adherence and health-related quality of life (HRQoL) of Slovenian patients with chronic obstructive pulmonary disease (COPD) and examined the factors associated with HRQoL. Demographic and therapy information was collected from 65 patients through interviews. The St. George’s Respiratory Questionnaire and the Morisky Medication Adherence Scale were used to evaluate HRQoL and adherence, resp. A multiple linear regression model was used to assess the association between the factors and HRQoL. The mean St. George’s Respiratory Questionnaire score (range 0-100, with higher scores indicating lower HRQoL) was 41.4. COPD affected patients’ daily activities more than their social and psychological functioning. Slightly more than 53 % of the patients were optimally adherent, while 12 % were non-adherent. Patients with lower HRQoL had a larger number of medications for concomitant diseases, experienced COPD exacerbation in the last year, and had less education. No statistically significant correlation was found between medication adherence and HRQoL.

scholarly journals Association between medication adherence and health-related quality of life in patients with chronic obstructive pulmonary disease

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Boyuk Moradkhani ◽  
Samaneh Mollazadeh ◽  
Parastoo Niloofar ◽  
Afsaneh Bashiri ◽  
Mohammad Bagher Oghazian
Keyword(s):  
Quality Of Life ◽  
Chronic Obstructive Pulmonary Disease ◽  
Medication Adherence ◽  
Chronic Obstructive ◽  
Health Related Quality ◽  
Obstructive Pulmonary Disease ◽  
Copd Patients ◽  
Related Quality ◽  
Health Related

Abstract Background Chronic Obstructive Pulmonary Disease (COPD) is one of the prominent cause of mortality worldwide. Nowadays, the level of medication adherence in COPD patients is very low, which reduces the clinical therapeutic effects. The purpose of the present study is to investigate the relationship between medication adherence and Health-Related Quality of Life (HRQoL) in COPD patients referred to the pulmonologist’s office. Methods This observational study was performed on 100 COPD outpatient cases. Each patient was interviewed to answer questionnaires regarding demographic and clinical information. To assess quality of life, health status, and severity of dyspnea, the St George’s Respiratory Questionnaire - COPD-Specific Version (SGRQ-C), COPD Assessment Test (CAT), and Modified British Medical Research Council (mMRC) questionnaires were used, respectively. Persian version of the Morisky Medication Adherence Scale (MMAS-8-Item) was used to measure medication adherence. To determine the adherence predictors, an ordinal logistic regression analysis was performed. Results Out of 100 patients with mean (±SD) age of 61.35 (±10.79) years, 74% had medium and high medication adherence. In the final ordinal logistic model, quality of life, health status, and education level found to have positive effect on medication adherence while polypharmacy had negative effect. We did not find any significant association between age, gender, Body Mass Index (BMI), and other variables with medication adherence. Conclusions Patients with high quality of life are more adherent to their medications. Furthermore, patients who have polypharmacy, tend to have less adherence to their medications.

scholarly journals Impact of cataract on health-related quality of life in a longitudinal Japanese chronic obstructive pulmonary cohort

2017 ◽  
Vol 15 (4) ◽  
pp. 329-338 ◽  
Author(s):  
Hidehiro Irie ◽  
Shotaro Chubachi ◽  
Minako Sato ◽  
Mamoru Sasaki ◽  
Naofumi Kameyama ◽  
...  
Keyword(s):  
Quality Of Life ◽  
At Risk ◽  
Chronic Obstructive ◽  
Health Related Quality ◽  
Obstructive Pulmonary Disease ◽  
Copd Patients ◽  
Related Quality ◽  
Health Related ◽  
St George's Respiratory Questionnaire

Cigarette smoking increases the risk of developing both cataract and chronic obstructive pulmonary disease (COPD). The prevalence of cataract and the clinical characteristics of COPD patients with cataract were retrospectively investigated in a 2-year observational COPD cohort. We analyzed 395 patients with complete data on ophthalmologic evaluation (319 subjects with COPD and 76 subjects at risk of COPD). There was no difference in the prevalence of cataract between COPD patients and those at risk (47.0% vs. 42.1%, p = 0.44). Age ≥ 75 years, low body mass index, and hypertension were independently associated with cataract as a comorbidity in COPD. The incidence of exacerbation within 2 years was significantly higher in COPD patients with cataract than those without cataract (36.6% vs. 18.3%, p = 0.0019). COPD patients with cataract exhibited significantly higher COPD assessment test score compared to those without cataract (13.7 ± 8.9 vs. 11.5 ± 7.2, p = 0.0240). Overall St George’s Respiratory Questionnaire score and each component were significantly worse in COPD patients with cataract compared to those without cataract. COPD patients with cataract exhibited poor health-related quality of life and frequent exacerbations. The association between cataract and exacerbations of COPD deserves further attention.

scholarly journals Relationship between degree of dyspnoea and health-related quality of life in patients with chronic obstructive pulmonary disease

2007 ◽  
Vol 135 (9-10) ◽  
pp. 547-553 ◽  
Author(s):  
Branislav Gvozdenovic ◽  
Sasa Mitic ◽  
Vladimir Zugic ◽  
Aleksandar Gvozdenovic ◽  
Nada Lazovic ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Measurement Properties ◽  
Chronic Obstructive ◽  
Health Related Quality ◽  
Obstructive Pulmonary Disease ◽  
Related Quality ◽  
Health Related

Introduction Dyspnoea is a characteristic symptom of chronic obstructive pulmonary disease (COPD), which impairs everyday functioning of patients. Objective The aim of our study was to evaluate the relationship between the degree of dyspnoea of COPD patients and their health-related quality of life. Method We measured the degree of dyspnoea and health-related quality of life in 85 COPD outpatients (46 male; mean age was 58 ? 12 years; mean forced expiratory volume in one second (FEV1) was 47.9?18.6% predicted). The degree of dyspnoea was assessed by Baseline Dyspnoea Index (BDI), List of Daily Activities (DAL), Visual Analogue Scale (VAS), Modified MRC Dyspnoea Scale, and Borg Category Scale (BCS). The patients filled two standardized questionnaires for measuring health-related quality of life: the generic one - 15D, and the respiratory specific one - the St George?s Respiratory Questionnaire (SGRQ). Total 15D and SGRQ scores, as well as the scores for individual domains of SGRQ (symptoms, activity and impact scores) for each patient were calculated. In 40 out of 85 patients, the same procedure was repeated at the follow-up, with a mean 4-week interval between the visits. Results There were statistically highly significant correlations (p<0.01) between values of all dyspnoea scale scores evaluated and all the health-related quality of life scores. The highest degree of correlation of both total SGRQ and 15D scores was found for the values of BCS (r=0.731 and -0.776, respectively). A statistically significant correlation between the changes of all SGRQ (but not 15D) scores and all dyspnoea score changes (except for MRC) were also recorded. Conclusion The degree of dyspnoea of COPD outpatients that could be well-determined by the scales used in our study clearly reflects the impairment of their health-related quality of life as assessed by the instruments used. All of the questionnaires we used in this study have good measurement properties for their purposes.

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