scholarly journals Metastatic Cholangiocarcinoma in a Bearded Dragon (Pogona vitticeps)

2020 ◽  
Vol 70 (2) ◽  
pp. 267-276
Author(s):  
Komenda Dominik ◽  
Dolenšek Tamara ◽  
Švara Tanja ◽  
Kastelic Marjan ◽  
Proks Pavel ◽  
...  
Keyword(s):  
Core Biopsy ◽  
Ultrasound Examination ◽  
Histopathological Examination ◽  
Limb Amputation ◽  
Histopathological Diagnosis ◽  
Coelomic Cavity ◽  
Tissue Core ◽  
Bearded Dragon ◽  
Pelvic Limb ◽  
Pogona Vitticeps

AbstractA 6.5-year-old female bearded dragon (Pogona vitticeps) was presented with a swollen right pelvic limb. A tissue core biopsy from the swollen area was performed and a presumptive histopathological diagnosis of adenocarcinoma was made. This diagnosis was confirmed after limb amputation. Two months after amputation a sudden deterioration in the overall health of the patient occurred. Ultrasound examination of the coelomic cavity revealed hypoechoic lesions in the liver. The patient was euthanized and submitted for necropsy which revealed a severely enlarged liver with multiple coalescing yellowish nodules. Cholangiocarcinoma of the liver with metastases to the spleen, left mesovarium and right pelvic limb was diagnosed after histopathological examination.

scholarly journals First case of intestinal leiomyosarcoma in a bearded dragon: Ultrasonographic findings

2016 ◽  
Vol 72 (5) ◽  
pp. 303-306
Author(s):  
Anna Łojszczyk-Szczepaniak ◽  
Anna Śmiech ◽  
Nadia Chlebicka ◽  
Klaudiusz O. Szczepaniak ◽  
Paweł Klimiuk
Keyword(s):  
Gastrointestinal Tract ◽  
Ultrasound Examination ◽  
Smooth Muscles ◽  
The Body ◽  
Focal Lesion ◽  
Histological Structure ◽  
Coelomic Cavity ◽  
Bearded Dragon ◽  
Pogona Vitticeps ◽  
Small Intestinal

The paper presents a case of leiomyosarcoma of the gastrointestinal tract in a bearded dragon (Pogona vitticeps) with an ultrasound and histopathological description of pathological changes. According to our knowledge, leiomyosarcoma of the gastrointestinal tract and its ultrasound features have not been reported in lizards yet. A male bearded dragon (Pogona vitticeps), aged 4 years, was referred for radiological and ultrasound examination with a history of apathy and loss of appetite. A preliminary diagnosis of an advanced neoplasia process in the caudal coelomic cavity was established by diagnostic imaging methods. The owner decided to euthanize the animal and agreed to a post-mortem examination. After euthanasia, a histopathological examination was performed. In a radiological examination, an irregularly marginated radiopacity measuring 5.8 x 4.0 cm was visible in the central part of the coelom. Serosal margin details in the coelomic cavity were decreased, and differentiation of coelomic organs was impossible. An ultrasound examination confirmed a large amount of free echogenic fluid in the coelomic cavity. The liver had increased echogenicity, and a hypoechoic focal lesion was found in the right lobe. Mixed echogenicity masses were visible in the caudal coelom adjacent to the small intestinal loops. In one of the adjacent intestinal loops, a focal thickening of the small intestinal wall was observed with loss of the normal layered architecture. The mass had complex and mostly low echogenicity with a cystic lesion present in the centre. Necropsy confirmed the presence of proliferative lesions in the body cavity, originating from the intestine and infiltrating the mesentery and the lumbar spine area as well as the gonads located at this site. On the basis of the histological structure of the intestinal tumour, the neoplastic proliferation was classified, according to the WHO classification, to a group of malignant tumours with characteristics of leiomyosarcoma and arising from the smooth muscles. The ultrasonographic features of gastrointestinal leiomyosarcoma in that lizard corresponded to features found in dogs, in which such tumours occur as eccentric, poorly echogenic masses with anechoic cavities in large changes. Leiomyosarcoma in reptiles can be locally invasive as well. Metastatic foci are also possible, especially in the liver.

Diagnosis and surgical management of idiopathic bile duct cysts in a bearded dragon (Pogona vitticeps)

2022 ◽  
Vol 27 (1) ◽  
pp. 1-5
Author(s):  
Anna Linda Nógrádi ◽  
Iain Cope ◽  
Dóra Csatári ◽  
Attila Arany-Tóth ◽  
Zoltán Dudás-Györki ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Bile Duct ◽  
Surgical Management ◽  
Liver Tissue ◽  
Histopathological Examination ◽  
Clinical Signs ◽  
Large Cyst ◽  
Soft Mass ◽  
Bearded Dragon ◽  
Pogona Vitticeps

The case presented shows the clinical signs, diagnosis and surgical management of idiopathic bile duct cysts in a bearded dragon (Pogona vitticeps). A 12-year-old female bearded dragon presented with constipation resulting from the consumption of sand. A soft mass about 4 cm wide could be palpated in the mid-coelom after the substrate passed. The animal started eating, but soon started showing signs of kyphosis. Ultrasound, radiography and computed tomography examinations revealed that the mass was a cyst 4 cm in diameter. Diagnostic laparotomy was performed and the large cyst and affected liver tissue were removed with a partial hepatectomy. Cytology of the cyst was unremarkable, but histopathological examination showed the lesions to be bile duct cysts. No sign of malignancy or inflammation could be seen.

scholarly journals Histopathological audit of appendectomy specimen in a Tertiary Care Center.

2019 ◽  
Vol 26 (10) ◽  
pp. 1702-1705
Author(s):  
Sikandar-e-Azam Yousfani ◽  
Inayat Ali Zardari ◽  
Mashoque Ali Khoja
Keyword(s):  
Acute Appendicitis ◽  
Ct Scan ◽  
Ultrasound Examination ◽  
Histopathological Examination ◽  
Care Center ◽  
Tertiary Care ◽  
Mucinous Cystadenoma ◽  
Histopathological Analysis ◽  
Negative Appendectomy ◽  
Histopathological Diagnosis

Objectives: To evaluate the histopathological findings in appendectomy specimens and observe the negative appendectomy rate (NAR). Study Design: Observational study. Setting: Department of Surgery Unit III, Peoples University of Medical & Health Sciences, Nawabshah. Period: January to December 2018.  Material and Methods: 117 consecutive cases of appendectomy. All the demographic data and the clinicopathological details were recorded on a proforma designed for the study. The histopathological assessment was carried out in all cases. The ultrasound examination and CT scan was carried out in selected cases. The data collected was statistically analyzed and the results were tabulated. Results: During study period 117 appendectomies were performed. The mean age of patient was 27+9.4 years, majority of patients (53.8%) were females with female to male ratio of 1.2:1. The histopathological diagnosis was made in all cases and the results indicates that 105 cases having positive appendectomy and in 12 (10.3%) cases the appendix was found histologically normal. Among 105 positive cases, 97 (83%) were diagnosed as acute appendicitis, 2 (1.7%) cases show fibrous obliteration and 6 (5.1%) cases were having unusual pathologies. The cases having histological diagnosis of acute appendicitis includs acute mucosal appendicitis, acute suppurative appendicitis with or without periappendicitis and peritonitis, acute necrotizing appendicitis and perforated gangrenous appendicitis. The 6 cases of unusual pathologies includes 3 cases of granulomatous lesions and one case each of carcinoid tumor, mucinous cystadenoma and worm infestation. The ultrasound was performed in 48 (41%) patients out of them 30 cases had positive findings on ultrasound examination were confirmed on histological examination and all 5 positive cases that were reported on CT scan were confirmed on histopathological examination. Conclusion: High rates of negative appendectomy in the female sex were observed, that can be reduced by the use of diagnostic imaging modalities specially ultrasound. The findings of abnormal pathologies on histopathological examination of the appendix suggest that histopathological analysis is necessary in all of the resected specimens.

F.N.A.C. AS DIAGNOSTIC TOOL OF PAROTID TUMORS AND ASSOCIATED PITFALLS IN CORRELATION WITH HISTOPATHOLOGY

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Bhawana Pant ◽  
Sanjay Gaur ◽  
Prabhat Pant
Keyword(s):  
Preoperative Diagnosis ◽  
Histopathological Examination ◽  
Clinical Information ◽  
Final Diagnosis ◽  
Needle Aspiration ◽  
Histopathological Diagnosis ◽  
Cytological Diagnosis ◽  
Tertiary Referral Centre ◽  
Clear Cut ◽  
Parotid Tumors

F.NA.C has been used for ages as a safe and economical tool for fast preoperative diagnosis of parotid tumors. It has certain pitfall which sometimes leads to misdiagnosis and consequently it may have affect on treatment of the tumors. Keeping in view of the diverse classification of parotid tumors’ information from cytology should be combined with radiology as well as clinical diagnosis. Aim: To discuss some cases where there was discrepancy between cytological diagnosis and histopathological result and also suggest measures to improve the efficacy of F.N.A.C. Material and methods: The study includes 50 cases of parotid tumours who presented to the  department of ENT at Government medical college Haldwani which is a tertiary referral centre during 2009 to 2016. Only adult patients were included and inflammatory swelling were excluded from the study. All patients evaluated  Contrast enhanced computerized tomography(CECT) and  Magnetic resonance imaging (MRI) followed by Fine needle aspiration cytology .Preoperative diagnosis was made upon the findings of the above investigations and different types of  parotid surgeries  were done. . Final diagnosis was made on  histopathological  examination. Result :The most common tumour  came out to be pleomorphic adenoma (23 cases-46%) followed by mucoepidermoid carcinoma(12cases-24%). In ten  cases there was no clear cut  association between cytological diagnosis and final histopathological diagnosis. Conclusion: FNAC is highly sensitive and specific technique for diagnosis of many salivary gland swellings. FNAC can be used preoperatively to avoid unnecessary surgery and biopsy. Details of clinical information and radiologic features may help the pathologist to arrive at the appropriate diagnosis and reduce false interpretation. Pitfalls may also occur with improper technique of FNAC which can be overcome by proper caution.

A case of diagnosis of a giant fetal cervical teratoma

2018 ◽  
Author(s):  
S.V. Idimesheva, E.G. Bazhenova, V.A. Vedernikov
Keyword(s):  
Magnetic Resonance Imaging ◽  
Ultrasound Examination ◽  
Mature Teratoma ◽  
Tumor Resection ◽  
Histopathological Diagnosis ◽  
Resonance Imaging ◽  
Cervical Tumor ◽  
Third Trimester ◽  
The Third ◽  
Cervical Teratoma

А case of ultrasound diagnosis of the giant fetal cervical tumor in the third trimester of gestation is presented. The diagnosis of a cervical teratoma was supposed by ultrasound examination and magnetic resonance imaging. The tumor resection was successfully performed at 6 days of life. Histopathological diagnosis was mature teratoma.

scholarly journals Clinical Value of CT-Guided Fine Needle Aspiration and Tissue-Core Biopsy of Thoracic Masses in the Dog and Cat

Animals ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 883
Author(s):  
Massimo Vignoli ◽  
Roberto Tamburro ◽  
Andrea Felici ◽  
Francesca Del Signore ◽  
Annalisa Dettori ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Core Biopsy ◽  
Needle Aspiration ◽  
Clinical Value ◽  
Reliable Technique ◽  
Ct Guided ◽  
Fine Needle ◽  
Tissue Core ◽  
Histopathologic Diagnosis ◽  
Ct Guided Biopsy

Diagnosis of thoracic lesions on the basis of history and physical examination is often challenging. Diagnostic imaging is therefore of paramount importance in this field. Radiology has traditionally been considered the diagnostic procedure of choice for these diseases. Nevertheless, it is often not possible to differentiate inflammatory/infectious lesions from neoplastic diseases. A correct cytological and histopathologic diagnosis is therefore needed for an accurate diagnosis and subsequent prognostic and therapeutic approach. In human medicine, Computed Tomography (CT) and CT-guided biopsy are used in the presence of lesions which are not adequately diagnosed with other procedures. In the present study, thoracic lesions from 52 dogs and 10 cats of different sex, breed and size underwent both CT-guided fine-needle aspiration (FNAB) and tissue-core biopsy (TCB). Clinical examination, hematobiochemical analysis and chest radiography were performed on all animals. In this study, 59 of 62 histopathological samples were diagnostic (95.2%). Cytology was diagnostic in 43 of 62 samples (69.4%). General sensitivity, accuracy and PPV for FNAB and TCB were 67.7%, 67.7% and 100% and 96.7%, 95.2% and 98.3%, respectively. Combining the two techniques, the overall mean accuracy for diagnosis was 98.4%. Nineteen of 62 cases showed complications (30.6%). Mild pneumothorax was seen in 16 cases, whereas mild hemorrhage occurred in three cases. No major complications were encountered. CT-guided FNAB cytology can be considered a useful and reliable technique, especially for small lesions or lesions located close to vital organs and therefore dangerous to biopsy in other way.

scholarly journals Percutaneous C-Arm Free O-Arm Navigated Biopsy for Spinal Pathologies: A Technical Note

Diagnostics ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 636
Author(s):  
Masato Tanaka ◽  
Sumeet Sonawane ◽  
Koji Uotani ◽  
Yoshihiro Fujiwara ◽  
Kittipong Sessumpun ◽  
...  
Keyword(s):  
Histopathological Examination ◽  
Correct Diagnosis ◽  
Standard Technique ◽  
Percutaneous Biopsy ◽  
Technical Note ◽  
Spinal Tumors ◽  
Histopathological Diagnosis ◽  
Ct Guided ◽  
Ct Guided Biopsy ◽  
The Right

Background: Percutaneous biopsy under computed tomography (CT) guidance is a standard technique to obtain a definitive diagnosis when spinal tumors, metastases or infections are suspected. However, specimens obtained using a needle are sometimes inadequate for correct diagnosis. This report describes a unique biopsy technique which is C-arm free O-arm navigated using microforceps. This has not been previously described as a biopsy procedure. Case description: A 74-year-old man with T1 vertebra pathology was referred to our hospital with muscle weakness of the right hand, clumsiness and cervicothoracic pain. CT-guided biopsy was performed, but histopathological diagnosis could not be obtained due to insufficient tissue. The patient then underwent biopsy under O-arm navigation, so we could obtain sufficient tissue and small cell carcinoma was diagnosed on histopathological examination. A patient later received chemotherapy and radiation. Conclusions: C-arm free O-arm navigated biopsy is an effective technique for obtaining sufficient material from spine pathologies. Tissue from an exact pathological site can be obtained with 3-D images. This new O-arm navigation biopsy may provide an alternative to repeat CT-guided or open biopsy.

A Description of Isospora amphiboluri (Apicomplexa: Eimeriidae) from the Inland Bearded Dragon, Pogona vitticeps (Sauria: Agamidae)

1995 ◽  
Vol 81 (2) ◽  
pp. 281 ◽  
Author(s):  
Chris T. McAllister ◽  
Steve J. Upton ◽  
Elliott R. Jacobson ◽  
Wayne Kopit
Keyword(s):  
Bearded Dragon ◽  
Pogona Vitticeps

scholarly journals Histopathological Analysis of Endometrial Biopsy in Gandaki Medical College Teaching Hospital, Pokhara, Nepal

2019 ◽  
Vol 12 (1) ◽  
pp. 25-30
Author(s):  
B Parajuli ◽  
G Pun ◽  
S Ranabhat ◽  
S Poudel
Keyword(s):  
Histopathological Examination ◽  
Hydatidiform Mole ◽  
College Teaching ◽  
Histopathological Diagnosis ◽  
Age Group ◽  
Medical College ◽  
Dilatation And Curettage ◽  
Partial Mole ◽  
Proliferative Endometrium ◽  
The Common

Objective: To study the spectrum of histopathological diagnosis of endometrial lesions and their distribution according to age. Methods: All the endometrium samples obtained by the procedure of dilatation and curettage and hysterectomy sent for histopathological examination at Pathology Department of Gandaki Medical College Teaching Hospital, Pokhara, Nepal. The study duration was total 12 months ranging from July 2016 to June 2017. All the endometrial samples were processed, sectioned at 4 - 6 μm and stained with routine H & E stain. Patient’s data including age, sex, procedure of the biopsy taken and histopathological diagnosis were noted. A pathologist, using Olympus microscope, reported the slides. Cases were reviewed by a second pathologist whenever necessary. Results: A total of 128 cases were studied. The most common histopathological diagnosis was proliferative endometrium (28.9%) followed by disorder proliferative endometrium (15.65%). Most of the patients were in age group 36 - 45 years comprising 32.03%. Hydatidiform mole comprised of 7.03% and among Hydatidiform mole, partial mole was more common. Dilatation and curettage (82.8%) was the common procedure in compare to hysterectomy for the evaluation of endometrial lesions. Conclusions: In this study, we observed a variety of endometrial lesions. Most of them are benign; among benign, proliferative endometrium was the common histopathological diagnosis followed by disorder proliferative endometrium. Most common presenting age group was found to be at 36 - 45 years. In evaluation of hydatidiform mole, partial mole was more frequent in compare to complete mole. Conventional dilatation and curettage is the preferred method in developing countries with limited resource to screen endometrial lesion and therefore biopsy should be sent for histopathological examination. Thus histopathological examination of routinely stained hematoxylin and eosin is readily available and widely accepted standard technique for evaluation of the endometrial lesions.

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