scholarly journals Evaluation of Achillea, Matricaria, and Anthemis plants following selection for drought tolerance at seedling stages

2021 ◽  
Vol 49 (1) ◽  
pp. 80-91
Author(s):  
Parvin Salehi Shanjani ◽  
Leila Rasoulzadeh ◽  
Hamideh Javadi

Abstract The genetic potentials of eight species of Achillea (A. millefolium, A. fillipendulla, A. biebersteinii, A. nobilis, A. eriophora), Matricaria (M. ricotita), and Anthemis (An. haussknechtii and An. tinctoria) under drought conditions during the seedling stage were measured. Non-ionic water-soluble polymer polyethylene glycol (PEG, molecular weight 6000) was used to simulate water stress at five osmotic potential levels (0, –0.3, –0.6, –0.9, and –1.2 MPa). An acceptable threshold value for germination was osmotic potential –0.6 MPa, and the modest osmotic potential was –1.2 MPa for studied taxa. Seedlings of germinated at two control and osmotic potential –0.6 MPa (as an acceptable threshold value for germination) treatments were sowed in a field under rainfed conditions. Genetic differentiation of control plants (CP) versus early selected plants (ESP, germinated at osmotic potential –0.6 MPa) was studied using morphological, physiological, and molecular (ISSR) markers. No significant differences were observed between morphological traits of CP and ESP in all species, however, days to full flowering shortened in ESP. The physiological results demonstrate that under rainfed conditions, the ESP, in a quick response, collect osmolytes and amplify the activity of antioxidative enzymes to survive drought. The genetic relationship in the group of genotypes, that ISSR marker set it out, is affiliated to taxon even though AMOVA showed a partial differentiation between CP and ESP groups (21%). It was concluded that the selection of tolerating individuals at the seedling stage represents a likely positive strategy to have higher drought tolerance feature in plants under rainfed conditions.

Author(s):  
M. Jincya ◽  
V. Babu Rajendra Prasad ◽  
P. Jeyakumara ◽  
A. Senthila ◽  
N. Manivannan

Drought stress is one of the major constraints for pulse production which negatively affecting its growth and production. Screening and selection of desirable genotypes for drought tolerance is the first and foremost important step in pulse breeding program. In green gram standardization for moisture stress was done under laboratory conditions using various concentration of PEG 6000 and 50% seedling mortality was observed at 0.5 MPa of moisture stress. Using this level of moisture stress 108 green gram genotypes were screened for their drought tolerance at seedling level and the following parameters viz., germination percentage, promptness index, radicle length, root length stress index, germination stress index and seed vigour were recorded. Observations revealed that the following green gram genotypes COGG 1332, VGG 16069, VGG 17003, VGG 17004, VGG 17009, VGG 17019 and VGG 17045 were found highly tolerant to moisture stress at seedling stage.


2011 ◽  
Vol 8 (2) ◽  
pp. 33
Author(s):  
Norfaezah Mazalan ◽  
Mazatulikhma Mat Zain ◽  
Nor Saliyana Jumali ◽  
Norhanim Mohalid ◽  
Zurina Shaameri ◽  
...  

Recently, research and development in the field of drug delivery systems (DDS) facilitating site-specific therapy has reached significant progression. DDS based on polymer micelles, coated micro- and nanoparticles, and various prodrug systems including water-soluble polymer have been prepared and extensively studied as novel drugs designed for cancer chemotherapy and brain delivery. Since polymers are going to be used in human, this study has the interest of testing two types of polymer, polyimides (PI) and polyphenylenevinylene (PPV) on neuronal cells. The objective of this study was to determine the possible neurotoxicity and potential neuroprotective effects of PI and PPV towards SH-SY5Y neuronal cells challenged by hydrogen peroxide (H2O2) as an oxidant. Cells were pretreated with either PI or PPV for 1 hour followed by incubation for 24 hour with 100 µM of H2O2. MTS assay was used to assess cell viability. Results show that PI and PPV are not harmful within the concentration up to 10 µM and 100 µM, respectively. However, PI and PPV do not protect neuronal cells against toxicity induced by H2O2 or further up the cell death.


Author(s):  
Sumant Saini ◽  
Yashwant .

Solid dispersions are one of the most promising strategies to improve the oral bioavailability of poorly water soluble drugs. By reducing drug particle size to the absolute minimum, and hence improving drug wettability, bioavailability may be significantly improved. This article reviews the various preparation techniques for solid dispersion and compiles some of the recent technology transfers. The different types of solid dispersions based on the molecular arrangement have been highlighted. Some of the practical aspects to be considered for the preparation of solid dispersions, such as selection of carrier, solvent and methods of physicochemical characterization, along with an insight into the molecular arrangement of drugs in solid dispersions are also discussed. In this review, it is intended to discuss the recent advances related on the area of solid dispersions.


2013 ◽  
Vol 38 (4) ◽  
pp. 366-372
Author(s):  
Xiao-qing WANG ◽  
Mao-chang TANG ◽  
Jie HUANG ◽  
Zi-fan LIU ◽  
Juan XU ◽  
...  

2021 ◽  
Author(s):  
Aranee Pleng Teepakakorn ◽  
Makoto Ogawa

Water-induced self-healing materials were prepared by the hybridization of a water-soluble polymer, poly(vinyl alcohol), with a smectite clay by mixing in an aqueous media and subsequent casting. Without using chemical...


2021 ◽  
Vol 11 (9) ◽  
pp. 3836
Author(s):  
Valeri Gitis ◽  
Alexander Derendyaev ◽  
Konstantin Petrov ◽  
Eugene Yurkov ◽  
Sergey Pirogov ◽  
...  

Prostate cancer is the second most frequent malignancy (after lung cancer). Preoperative staging of PCa is the basis for the selection of adequate treatment tactics. In particular, an urgent problem is the classification of indolent and aggressive forms of PCa in patients with the initial stages of the tumor process. To solve this problem, we propose to use a new binary classification machine-learning method. The proposed method of monotonic functions uses a model in which the disease’s form is determined by the severity of the patient’s condition. It is assumed that the patient’s condition is the easier, the less the deviation of the indicators from the normal values inherent in healthy people. This assumption means that the severity (form) of the disease can be represented by monotonic functions from the values of the deviation of the patient’s indicators beyond the normal range. The method is used to solve the problem of classifying patients with indolent and aggressive forms of prostate cancer according to pretreatment data. The learning algorithm is nonparametric. At the same time, it allows an explanation of the classification results in the form of a logical function. To do this, you should indicate to the algorithm either the threshold value of the probability of successful classification of patients with an indolent form of PCa, or the threshold value of the probability of misclassification of patients with an aggressive form of PCa disease. The examples of logical rules given in the article show that they are quite simple and can be easily interpreted in terms of preoperative indicators of the form of the disease.


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