scholarly journals The efficacy of scaling root planing to inflammation biomarker of periodontitis patients with atherosclerosis

2021 ◽  
Vol 6 (1) ◽  
pp. 41-50
Author(s):  
Sekar SAFITRI ◽  
Agus SUSANTO ◽  
Ina HENDIANI
Keyword(s):  
Lipid Profile ◽  
Meta Analysis ◽  
Rapid Review ◽  
National Library ◽  
Dental Tissue ◽  
Exclusion Criteria ◽  
Inflammatory Biomarker ◽  
Root Planing ◽  
Positive Effect ◽  
Progression Of Atherosclerosis

ABSTRACT Periodontitis is a disease of surrounding dental tissue with a prevalence of 74.1% inIndonesia. Many studies show periodontitis plays a role in the progression of atherosclerosis. Therelationship between these two conditions shows that scaling root planing intervention can reduce therisk of atherosclerosis. This study aimed to know the efficacy of scaling root planing on changes ininflammatory biomarkers in periodontitis patients with atherosclerosis. This systematic literature reviewwas conducted using the Rapid Review method that refers to the Preferred Reporting Items forSystematic Review and Meta-Analysis (PRISMA) guidelines. Electronic searches were carried out from 4electronic databases, including the National Library of Medicine (Medline / PubMed), The CochraneLibrary, EbscoHOST, and SAGE Journal. Inclusion and exclusion criteria selected 6 RCT articles to beanalyzed qualitatively. Within 2 to 6 months, research in 6 RCT articles showed the results insignificantly reducing CRP levels as the main biomarkers of atherosclerosis after scaling root planingintervention. Other biomarkers that were also assessed are cytokines levels, lipid profile components,WBC, and fibrinogen. Overall results showed a positive effect of scaling root planing intervention inreducing the inflammatory biomarker levels of atherosclerosis in periodontitis patients withatherosclerosis. The treatment of scaling root planing is considered effective in reducing theinflammatory biomarker levels of atherosclerosis in periodontitis patients with atherosclerosis to reducethe level of risk. KEYWORDS: scaling root planing, inflammatory biomarker, atherosclerosis

Effects of grape products on blood lipids: a systematic review and dose–response meta-analysis of randomized controlled trials

2019 ◽  
Vol 10 (10) ◽  
pp. 6399-6416 ◽  
Author(s):  
Ehsan Ghaedi ◽  
Sajjad Moradi ◽  
Zahra Aslani ◽  
Hamed Kord-Varkaneh ◽  
Maryam Miraghajani ◽  
...  
Keyword(s):  
Systematic Review ◽  
Lipid Profile ◽  
Dose Response ◽  
Blood Lipids ◽  
Meta Analysis ◽  
Mechanisms Of Action ◽  
Controlled Trials ◽  
Randomized Controlled ◽  
Positive Effect ◽  
Present Systematic Review

Grape products through several plausible mechanisms-of-action are reported to improve lipid profile. The present systematic review revealed that grape product supplementation might have a positive effect on achieving a lipid profile target.

The Effects of Coenzyme Q10 Supplementation on Lipid Profiles Among Patients with Metabolic Diseases: A Systematic Review and Meta-analysis of Randomized Controlled Trials

2018 ◽  
Vol 24 (23) ◽  
pp. 2729-2742 ◽  
Author(s):  
Nasrin Sharifi ◽  
Reza Tabrizi ◽  
Mahmood Moosazadeh ◽  
Naghmeh Mirhosseini ◽  
Kamran B. Lankarani ◽  
...  
Keyword(s):  
Systematic Review ◽  
Lipid Profile ◽  
Coenzyme Q10 ◽  
Metabolic Disorders ◽  
Metabolic Diseases ◽  
Meta Analysis ◽  
Lipid Profiles ◽  
Controlled Trials ◽  
Serum Triglycerides ◽  
Coq10 Supplementation

Background and objective: Oxidative stress and inflammation are key parameters in developing metabolic disorders. Hence, antioxidant intake might be an appropriate approach. Several studies have evaluated the effect of coenzyme Q10 (CoQ10) supplementation on lipid profile among patients with metabolic diseases, though findings are controversial. The aim of this systematic review and meta-analysis was to determine the effects of CoQ10 supplementation on lipid profile in patients with metabolic disorders. Methods: We searched PubMed, EMBASE, Web of Science and Cochrane Library databases until July 2017. Prospective clinical trials were selected assessing the effect of CoQ10 supplementation on different biomarkers. Two reviewers independently assessed the eligibility of studies, extracted data, and evaluated the risk of bias of included studies. A fixed- or random-effects model was used to pool the data, which expressed as a standardized mean difference with 95% confidence interval. Heterogeneity was measured using a Q-test and with I2 statistics. Results: A total of twenty-one controlled trials (514 patients and 525 controls) were included. The meta-analysis indicated a significant reduction in serum triglycerides levels (SMD -0.28; 95% CI, -0.56, -0.005). CoQ10 supplementation also decreased total-cholesterol (SMD -0.07; 95% CI, -0.45, 0.31), increased LDL- (SMD 0.04; 95% CI, -0.27, 0.36), and HDL-cholesterol levels (SMD 0.10; 95% CI, -0.32, 0.51), not statistically significant. Conclusion: CoQ10 supplementation may significantly reduce serum triglycerides levels, and help to improve lipid profiles in patients with metabolic disorders. Additional prospective studies are recommended using higher supplementation doses and longer intervention period.

Effect of fenugreek consumption on serum lipid profile: A systematic review and meta‐analysis

2020 ◽  
Vol 34 (9) ◽  
pp. 2230-2245 ◽  
Author(s):  
Kiyan Heshmat‐Ghahdarijani ◽  
Neda Mashayekhiasl ◽  
Atefeh Amerizadeh ◽  
Zahra Teimouri Jervekani ◽  
Masoumeh Sadeghi
Keyword(s):  
Systematic Review ◽  
Lipid Profile ◽  
Serum Lipid ◽  
Meta Analysis ◽  
Serum Lipid Profile

scholarly journals The effect of rTMS in the management of pain associated with CRPS

2020 ◽  
Vol 11 (1) ◽  
pp. 363-370
Author(s):  
Min Cheol Chang ◽  
Sang Gyu Kwak ◽  
Donghwi Park
Keyword(s):  
Repetitive Transcranial Magnetic Stimulation ◽  
Controlled Trial ◽  
Meta Analysis ◽  
Pain Syndrome ◽  
Treatment Session ◽  
Cochrane Library ◽  
Exclusion Criteria ◽  
Analgesic Effects ◽  
Randomized Controlled ◽  
Before And After

AbstractBackgroundTherapeutic management of pain in patients with complex regional pain syndrome (CRPS) is challenging. Repetitive transcranial magnetic stimulation (rTMS) has analgesic effects on several types of pain. However, its effect on CRPS has not been elucidated clearly. Therefore, we conducted a meta-analysis of the available clinical studies on rTMS treatment in patients with CRPS.Materials and methodsA comprehensive literature search was conducted using the PubMed, EMBASE, Cochrane Library, and SCOPUS databases. We included studies published up to February 09, 2020, that fulfilled our inclusion and exclusion criteria. Data regarding measurement of pain using the visual analog scale before and after rTMS treatment were collected to perform the meta-analysis. The meta-analysis was performed using Comprehensive Meta-analysis Version 2.ResultsA total of three studies (one randomized controlled trial and two prospective observational studies) involving 41 patients were included in this meta-analysis. No significant reduction in pain was observed immediately after one rTMS treatment session or immediately after the entire schedule of rTMS treatment sessions (5 or 10 sessions; P > 0.05). However, pain significantly reduced 1 week after the entire schedule of rTMS sessions (P < 0.001).ConclusionrTMS appears to have a functional analgesic effect in patients with CRPS.

scholarly journals Lipid profile and prognosis in patients with coronary heart disease: a meta-analysis of prospective cohort studies

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xiangmei Zhao ◽  
Dongying Wang ◽  
Lijie Qin
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Cohort Studies ◽  
Lipid Profile ◽  
Prospective Cohort ◽  
Cardiac Death ◽  
Meta Analysis ◽  
Prospective Cohort Studies ◽  
All Cause Mortality ◽  
Reduced Risk

Abstract Background This meta-analysis based on prospective cohort studies aimed to evaluate the associations of lipid profiles with the risk of major adverse cardiovascular outcomes in patients with coronary heart disease (CHD). Methods The PubMed, Embase, and Cochrane Library electronic databases were systematically searched for prospective cohort study published through December 2019, and the pooled results were calculated using the random-effects model. Results Twenty-one studies with a total of 76,221 patients with CHD met the inclusion criteria. The per standard deviation (SD) increase in triglyceride was associated with a reduced risk of major adverse cardiovascular events (MACE). Furthermore, the per SD increase in high-density lipoprotein cholesterol (HDL-C) was associated with a reduced risk of cardiac death, whereas patients with lower HDL-C were associated with an increased risk of MACE, all-cause mortality, and cardiac death. Finally, the risk of MACE was significantly increased in patients with CHD with high lipoprotein(a) levels. Conclusions The results of this study suggested that lipid profile variables could predict major cardiovascular outcomes and all-cause mortality in patients with CHD.

The effect of almond intake on lipid profile: a systematic review and meta-analysis of randomized controlled trials

2021 ◽  
Author(s):  
Omid Asbaghi ◽  
Vihan Moodi ◽  
Amir Hadi ◽  
Elham Eslampour ◽  
Mina Shirinbakhshmasoleh ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Randomized Controlled Trials ◽  
Lipid Profile ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Randomized Controlled

A number of clinical trials have examined the effect of almond intake on the lipid profile in recent years; however, the results remain equivocal.

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