EFFECT OF INTRACAMERAL IMPLANTATION OF PLASMA-MODIFIED POLYLACTIC ACID FILMS ON THE COURSE OF IN VIVO-INDUCED BULLOUS KERATOPATHY

2021 ◽  
pp. 32-38
Author(s):  
E.O. FILIPPOVA ◽  
◽  
N.M. IVANOVA ◽  
V.F. PICHUGIN ◽  
◽  
...  
Keyword(s):  
Low Temperature ◽  
Polylactic Acid ◽  
Atmospheric Pressure ◽  
Atmospheric Pressure Plasma ◽  
Bullous Keratopathy ◽  
Pressure Plasma

To determine the effect of intracameral implantation of polylactic acid (PLA) films modified in low-temperature atmospheric pressure plasma on the course of in vivo-induced bullous keratopathy (BK).

scholarly journals Assessment of quality and safety of pork treated with low-temperature atmospheric-pressure plasma

2021 ◽  
Vol 6 (1) ◽  
pp. 78-86
Author(s):  
N. Yu. Moskalenko ◽  
O. A. Kudryashova ◽  
L. S. Kudryashov ◽  
S. L. Tikhonov ◽  
N. V. Tikhonova ◽  
...  
Keyword(s):  
Low Temperature ◽  
Atmospheric Pressure ◽  
Cold Treatment ◽  
Meat Product ◽  
Argon Plasma ◽  
Atmospheric Pressure Plasma ◽  
Weight Fraction ◽  
Microbial Inactivation ◽  
Temperature Plasma ◽  
Pressure Plasma

It is known that processing methods ensuring partial or full microbial inactivation are quite limited. Therefore, it is of great interest to develop technique and technologies allowing the effective action on microorganisms without a significant influence on product properties. The use of cold plasma can be one of the promising methods of meat product treatment by cold sterilization. The present work examines a possibility of chilled meat treatment with low-temperature atmospheric-pressure plasma to increase its stability to microbial spoilage and extend shelf life. To obtain low temperature plasma, the equipment developed by the designing department “Plasmamed” was used. Chilled meat was treated with low-temperature atmospheric-pressure argon plasma for 5, 10, 20 and 30 min. Samples were stored at a temperature of 2–4 °C for 10 days. Organoleptic indices, moisture weight fraction, changes in pH and water activity were analyzed before treatment and during storage. Sanitary microbiological analyses were carried out by the following indicators: quantity of mesophilic aerobic and facultative anaerobic microorganisms (QMAFAnM), the presence and quantity of coliforms, Salmonella, Escherichia coli, Listeria monocytogenes, Proteus. It was shown that meat cold treatment with argon plasma inhibited the development of mesophilic microorganisms. The colony forming units detected in the samples after ten days of storage were determined by the duration of exposure to plasma. It was proved that meat treatment for 15 and 30 min had the bactericidal effect and facilitated an improvement in meat color during storage. The organoleptic indices of the samples treated with plasma corresponded to the requirements of standards and approved consumer characteristics.

scholarly journals Long-Term Risk Assessment for Medical Application of Cold Atmospheric Pressure Plasma

Diagnostics ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 210 ◽  
Author(s):  
Rico Rutkowski ◽  
Georg Daeschlein ◽  
Thomas von Woedtke ◽  
Ralf Smeets ◽  
Martin Gosau ◽  
...  
Keyword(s):  
Atmospheric Pressure ◽  
Atmospheric Pressure Plasma ◽  
Laser Scanning Microscopy ◽  
Confocal Laser ◽  
Plasma Medicine ◽  
Pressure Plasma ◽  
Cold Atmospheric Pressure Plasma

Despite increasing knowledge gained based on multidisciplinary research, plasma medicine still raises various questions regarding specific effects as well as potential risks. With regard to significant statements about in vivo applicability that cannot be prognosticated exclusively based on in vitro data, there is still a deficit of clinical data. This study included a clinical follow-up of five probands who had participated five years previously in a study on the influence of cold atmospheric pressure plasma (CAP) on the wound healing of CO2 laser-induced skin lesions. The follow-up included a complex imaging diagnostic involving dermatoscopy, confocal laser scanning microscopy (CLSM) and hyperspectral imaging (HSI). Hyperspectral analysis showed no relevant microcirculatory differences between plasma-treated and non-plasma-treated areas. In summary of all the findings, no malignant changes, inflammatory reactions or pathological changes in cell architecture could be detected in the plasma-treated areas. These unique in vivo long-term data contribute to a further increase in knowledge about important safety aspects in regenerative plasma medicine. However, to confirm these findings and secure indication-specific dose recommendations, further clinical studies are required.

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