scholarly journals Efficacy of clear aligners in producing molar distalization: Systematic review

2022 ◽  
Vol 11 ◽  
pp. 317-324
Author(s):  
Purva Verma ◽  
Ashwin Mathew George
Keyword(s):  
Systematic Review ◽  
Retrospective Studies ◽  
Good Control ◽  
Class Ii ◽  
Vertical Dimension ◽  
Google Scholar ◽  
Electronic Database ◽  
Molar Distalization ◽  
Manual Search ◽  
Complete Search

Objectives: The aim of this review is to systematically analyze the efficacy of molar distalization using clear aligners in non-growing Class II patients. Materials and Methods: A complete search across the electronic database through PubMed, Cochrane, Google scholar, LILACS, and manual search of orthodontic journals were done till 2019. Studies were selected on the basis of PRISMA guidelines. Results: A total of four articles were included in this review. The amount of molar distalization reported was 2–3 mm. Conclusion: Out of the four studies included. In all the studies a significant amount of distalization was reported. Three retrospective studies concluded that distalization with aligners is the most effective of all tooth movements. One study concluded that aligners effectively achieved distalization with an efficacy of 87%, other two studies concluded that aligners effectively distalized the molars with good control over vertical dimension and mesiodistal tipping.

scholarly journals Mindfulness-based positive psychology interventions: a systematic review

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Joshua George Allen ◽  
John Romate ◽  
Eslavath Rajkumar
Keyword(s):  
Systematic Review ◽  
Positive Psychology ◽  
Empirical Studies ◽  
Well Being ◽  
Current Paper ◽  
Google Scholar ◽  
Positive Outcomes ◽  
Positive Psychology Interventions ◽  
Manual Search ◽  
Comprehensive Manner

Abstract Background There are hundreds of mindfulness-based interventions in the form of structured and unstructured therapies, trainings, and meditation programs, mostly utilized in a clinical rather than a well-being perspective. The number of empirical studies on positive potentials of mindfulness is comparatively less, and their known status in academia is ambiguous. Hence, the current paper aimed to review the studies where mindfulness-based interventions had integrated positive psychology variables, in order to produce positive functioning. Methods Data were obtained from the databases of PubMed, Scopus, and PsycNet and manual search in Google Scholar. From the 3831 articles, irrelevant or inaccessible studies were eliminated, reducing the number of final articles chosen for review to 21. Interventions that contribute to enhancement of eudaimonia, hedonia, and other positive variables are discussed. Results Findings include the potential positive qualities of MBIs in producing specific positive outcomes within limited circumstances, and ascendancy of hedonia and other positive variables over eudaimonic enhancement. Conclusion In conclusion, exigency of modifications in the existing MBIs to bring about exclusively positive outcomes was identified, and observed the necessity of novel interventions for eudaimonic enhancement and elevation of hedonia in a comprehensive manner.

scholarly journals PARTISIPASI MASYARAKAT DALAM PENCEGAHAN PENYAKIT DEMAM BERDARAH DENGUE: SEBUAH TINJAUAN SISTEMATIKA

2020 ◽  
Vol 14 (1) ◽  
pp. 25-37
Author(s):  
Lia Meiliyana ◽  
Rita Damayanti ◽  
Zakianis Zakianis
Keyword(s):  
Systematic Review ◽  
Google Scholar ◽  
Electronic Database ◽  
Meta Analyses

Demam Berdarah Dengue (DBD) merupakan penyakit yang masih menjadi permasalahan global, karena tingkat insiden mengalami peningkatan 30 kali lipat selama 50 tahun terakhir. Partisipasi masyarakat amat dibutuhkan dalam keberlangsungan upaya pengendalian demam berdarah. Kesadaran diri kunci utama dalam berpartisipasi dipengaruhi faktor-faktor seperti pengetahuan, sikap dan perilaku. Penelitian ini menggunakan sistematika review untuk melihat upaya pencegahan demam berdarah berdasarkan partisipasi masyarakat. Strategi pencarian menggunakan 3 electronic database, EBSCO, Proquest dan Google Scholar dan mengikuti Protokol PRISMA (Preffered Reporting Items for Systematic Review and Meta Analyses), didapatkan sebanyak 17 artikel yang sesuai dengan kriteria inklusi dan ekslusi. Hasil tinjauan terdapat 4 variabel utama yang digunakan yaitu Sosiodemografi, Knowledge, Attitude dan Practice. Variabel sosiodemografi (umur dan pendidikan) mempunyai nilai signifikan pada 42,8% artikel, variabel pengetahuan cara pendegahan demam berdarah signifikan pada 23,1% artikel, variabel sikap terhadap tempat perindukan nyamuk dan upaya pengendalian vektor sebesar 53,8% artikel, dan variabel perilaku yang mempunyai signifikansi dengan prosentase tertinggi adalah perilaku yang dihubungkan dengan indeks entomologi sebesar 53,8% artikel. Tingkat pendidikan, pengetahuan, dan sikap positif terhadap upaya pencegahan demam berdarah belum tentu memberikan hasil signifikan terhadap perilaku. Dengan demikian peningkatan kesadaran tentang risiko, motivasi dan komunikasi diperlukan untuk mengubah perilaku

scholarly journals Cedarwood Oil as a Substitute for Xylene in Histopathological Laboratories – A Systematic Review

2021 ◽  
pp. 519-525
Author(s):  
R. Deepa Viswasini ◽  
Pratibha Ramani ◽  
Abhilasha Ramasubramanian
Keyword(s):  
Systematic Review ◽  
Aromatic Hydrocarbon ◽  
Gold Standard ◽  
Health Benefits ◽  
Google Scholar ◽  
Manual Search ◽  
Carcinogenic Potential ◽  
Good For ◽  
Google Search

Background: Xylene is an aromatic hydrocarbon that's extensively used as a deparaffinizing agent, and it's far extraordinarily biohazardous. It is proven to be the best chemical to be used in histopathological laboratories in spite of its carcinogenic potential. Aim: The aim of this study is to do a systematic review on the efficacy of cedarwood oil as clearing agent and deparaffinizing agent alternative to xylene in histopathological laboratories. Materials and Methods: The articles for this review were searched from PubMed, Google Scholar, Google search and manual search using the keywords cedarwood oil, natural substitute, natural alternative and xylene. The final of 3 articles were included in the review which compared the efficacy of cedarwood oil as a natural alternative with the gold standard xylene. Once the articles to be reviewed were finalized, data was collected, tabulated and was verified and interpreted. Results: Three articles included in this review showed considerable and acceptable results with cedarwood oil as clearing and deparaffinizing agent. Conclusion: Merits and demerits are equally found in both the reagents but compromising the time and cost in terms of cedarwood oil for health benefits hold good for the pathologists but bad for the patients. In case of xylene, compromising the health benefits of workers which results in quicker diagnosis hold good for the patients but not for the pathologists. Finally storage and disposal of these two reagents still remains questionable.

Time of maxillary molar distalization with non-compliance intraoral distalizing appliances: a meta-analysis

2019 ◽  
Vol 41 (6) ◽  
pp. 652-660 ◽  
Author(s):  
Silvio Augusto Bellini-Pereira ◽  
Daniela Cubas Pupulim ◽  
Aron Aliaga-Del Castillo ◽  
José Fernando Castanha Henriques ◽  
Guilherme Janson
Keyword(s):  
Systematic Review ◽  
Random Effects ◽  
Prospective Studies ◽  
Meta Analysis ◽  
Class Ii ◽  
Risk Of Bias ◽  
Cochrane Library ◽  
Molar Distalization ◽  
Maxillary Molar ◽  
The Mean

Summary Background/Objective To assess the mean maxillary molar distalization time with non-compliance intraoral distalizing appliances. Search methods and selection criteria Database search included PubMed, Web of Science, Scopus, The Cochrane Library, Lilacs, and a partial grey literature through Google Scholar and OpenGrey. The search was performed until May 2017 and updated on February 2019, without limitations regarding publication year or language. Controlled clinical trials (randomized and non-randomized prospective studies) reporting duration of maxillary molar distalization of Class II patients treated with intraoral distalizers were included. Data collection and analysis For the trials’ quality assessment, the Cochrane Risk of Bias tool and the Cochrane Collaboration’s ROBINS-I tool were used for the randomized controlled trials and non-randomized prospective studies, respectively. Database research, risk of bias (RoB) assessment, and extraction of data were performed by two independent investigators, with inclusion of a third reviewer, if disagreements emerged. Data was combined through a random-effects meta-analysis. Subgroup analyses regarding side of force application, type of anchorage, amount of molar distalization, and sensitivity analysis comparing study designs were also performed. Quality of evidence was assessed using the GRADE and SORT approaches. Results Nine studies were included in the qualitative analysis; however, a meta-analysis was performed with only four studies, due to the presence of high RoB in the other studies. The random-effects meta-analysis assumes that the mean distalization time with distalizers is 8.34 months (95% confidence interval: 6.10, 10.58). Another meta-analysis was performed to evaluate the relationship between distalization time and the type of anchorage (conventional or skeletal), resulting in no significant difference. Both meta-analyses presented low-quality evidence. Limitations The major limitation of this meta-analysis is the fact that distalization time can be affected by a great range of factors. Conclusions and implications Correction of a half-to-full cusp Class II molar relationship with intraoral distalizers can be achieved in 8.34 months, and this distalization time may not be affected by the kind of anchorage used. Registration The protocol for this systematic review was based on the Cochrane Handbook for Systematic Reviews of Interventions 5.1.0 and was registered at PROSPERO database (http://www.crd.york.ac.uk/PROSPERO/display_record.php?ID=CRD42017068737). This systematic review is reported according to the PRISMA statement.

Crizotinib Versus Chemotherapy on ALK-positive NSCLC: A Systematic Review of Efficacy and Safety

2018 ◽  
Vol 19 (1) ◽  
pp. 41-49 ◽  
Author(s):  
Mingxia Wang ◽  
Guanqi Wang ◽  
Haiyan Ma ◽  
Baoen Shan
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Adverse Events ◽  
Objective Response Rate ◽  
Retrospective Studies ◽  
Response Rate ◽  
Objective Response ◽  
Treated Group ◽  
Efficacy And Safety ◽  
Alk Positive

Introduction: Crizotinib was approved to treat anaplastic lymphoma kinase (ALK)- positive non-small cell lung cancer (NSCLC) by the Food and Drug Administration in 2011.We conducted a systematic review of clinical trials and retrospective studies to compare the efficacy and safety of crizotinib with chemotherapy. </P><P> Methods: We searched electronic databases from inception to Dec. 2016. Clinical trials and retrospective studies regarding crizotinib and crizotinib versus chemotherapy in treatment of NSCLC were eligible. The primary outcomes were the objective response rate (ORR) and disease control rate (DCR). Results: Nine studies (five clinical trials and four retrospective studies) including 729 patients met the inclusion criteria. Crizotinib treatment revealed 1-year OS of 77.1% and PFS of 9.17 months. And crizotinib had a better performance than chemotherapy in ORR (OR: 4.97, 95%CI: 3.16 to 7.83, P<0.00001, I2=35%). DCR revealed superiority with crizotinib than chemotherapy (OR: 3.42, 95% CI: 2.33 to 5.01, P<0.00001, I2=0%). PR (partial response) were significant superior to that of chemotherapy through direct systematic review. No statistically significant difference in CR (complete response) was found between crizotinib-treated group and chemotherapy-treated group. Regarding SD (stable disease), chemotherapy-treated group had a better performance than crizotinib-treated group. Common adverse events associated with crizotinib were visual disorder, gastrointestinal side effects, and elevated liver aminotransferase levels, whereas common adverse events with chemotherapy were fatigue, nausea, and hematologic toxicity. This systematic review revealed improved objective response rate and increased disease control rate in crizotinib group comparing with chemotherapy group. Crizotinib treatment would be a favorable treatment option for patients with ALK-positive NSCLC. ALK inhibitors may have future potential applications in other cancers driven by ALK or c-MET gene mutations.

Adverse Effects of Natural Products: A Brief Pre-Systematic Review

2020 ◽  
Vol 01 ◽  
Author(s):  
Carla Pires ◽  
Ana Fernandes
Keyword(s):  
Systematic Review ◽  
Adverse Event ◽  
Natural Products ◽  
Adverse Events ◽  
In Vitro Study ◽  
Google Scholar ◽  
Inclusion Criteria ◽  
Exclusion Criteria ◽  
Meta Analyses

Background: Natural products are commonly used for treating health problems. These products may be associated with adverse events, which are defined as "noxious and unintended response to a medicinal product" by the European Medicine Agency. Objectives: To identify studies describing at least one adverse event (or with potential to promote an adverse event) related to the use of natural products, as well as to describe the involved product(s) and adverse event(s). Methods: A pre-systematic review following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses criteria. Keywords: "natural product(s)" and ["adverse drug reaction(s)" or "adverse effect(s)"]. Screened databases: PubMed, SciELO, DOAJ and Google Scholar. Inclusion criteria: papers describing at least one adverse event associated with the use of natural products and published between 2017 and 2019. Exclusion criteria: Repeated studies, reviews and papers written in other languages than English, Portuguese, French or Spanish. Results: 104 studies were identified (20 PubMed; 0 SciELO; 2 DOAJ; 82 Google Scholar), but only 10 were selected (4 PubMed and 6 Google Scholar): 1 in-vitro study; 2 non-clinical studies, 1 study reporting in-vitro and clinical data and 5 studies were cases reports. Globally, 997 reports of adverse drug reactions with natural products were identified, mainly non-severe cases. Conclusion: Since a limited number of studies was found, we conclude that adverse events due to natural products may be underreported, or natural products may have a good safety profile. This review contributes for assuring the safety of natural products consumers, by evaluating the knowledge/information on the potential adverse events and interactions of these products.

Use of flowable resin composite as an intermediate layer in class II restorations: a systematic review and meta-analysis

2021 ◽  
Vol 25 (10) ◽  
pp. 5629-5639
Author(s):  
Cleber Paradzinski Cavalheiro ◽  
Helena Scherer ◽  
José Carlos Pettorossi Imparato ◽  
Fabrício Mezzomo Collares ◽  
Tathiane Larissa Lenzi
Keyword(s):  
Systematic Review ◽  
Intermediate Layer ◽  
Resin Composite ◽  
Meta Analysis ◽  
Class Ii

scholarly journals Evaluation of the Nasolabial Angle in Orthodontic Diagnosis: A Systematic Review

2021 ◽  
Vol 11 (6) ◽  
pp. 2531
Author(s):  
Vincenzo Quinzi ◽  
Licia Coceani Paskay ◽  
Nicola D’Andrea ◽  
Arianna Albani ◽  
Annalisa Monaco ◽  
...  
Keyword(s):  
Systematic Review ◽  
Hyaluronic Acid ◽  
Class Ii ◽  
Cochrane Library ◽  
Class Iii ◽  
Palatal Expansion ◽  
Rapid Palatal Expansion ◽  
Nasolabial Angle ◽  
Registration Number ◽  
Teeth Extraction

Background: This study is a systematic literature review aiming at identifying the variation of the average nasolabial angle (NLA) in various orthodontic situations. The NLA is one of the key factors to be studied in an orthodontic diagnosis for the aesthetics of the nose and facial profile. Methods: Out of 3118 articles resulting from four search engines (PubMed, Cochrane Library, Turning Research Into Practice (TRIP) and SciELO), the final study allowed the analysis and comparison of only 26 studies. These included studies have considered the NLA in the following cases: teeth extraction, class II malocclusion, class III malocclusion, rapid palatal expansion (RPE), orthognathic surgery, and non-surgical rhinoplasty with a hyaluronic acid filler. Results: The results indicate that teeth extraction and the use of hyaluronic acid fillers significantly affect the NLA. Conclusions: This systematic review shows that a statistically significant change in NLA values occurs in: extractive treatments of all four of the first or second premolars in class I patients; in class II patients with upper maxillary protrusion; in patients with maxillary biprotrusion, except for cases of severe crowding; and in patients undergoing non-surgical rhinoplasty with a hyaluronic acid filler. Trial registration number: PROSPERO CRD42020185166

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