The role of optical coherence tomography as a predictor of cognitive impairment in multiple sclerosis

2018 ◽  
Author(s):  
Cláudia Lima
Keyword(s):  
Multiple Sclerosis ◽  
Optical Coherence Tomography ◽  
Cognitive Impairment ◽  
Optical Coherence

scholarly journals The role of optical coherence tomography and infrared oculography in assessing the visual pathway and CNS in multiple sclerosis

2018 ◽  
Vol 8 (5) ◽  
pp. 323-335 ◽  
Author(s):  
Danko Coric ◽  
Jenny A Nij Bijvank ◽  
Laurentius J van Rijn ◽  
Axel Petzold ◽  
Lisanne J Balk
Keyword(s):  
Multiple Sclerosis ◽  
Optical Coherence Tomography ◽  
Visual Pathway ◽  
Optical Coherence

Optical coherence tomography and multiple sclerosis: Update on clinical application and role in clinical trials

2019 ◽  
Vol 26 (6) ◽  
pp. 624-639 ◽  
Author(s):  
Jeffrey Lambe ◽  
Shiv Saidha ◽  
Robert A Bermel
Keyword(s):  
Multiple Sclerosis ◽  
Clinical Trials ◽  
Optical Coherence Tomography ◽  
Retinal Layer ◽  
Optical Coherence ◽  
Neuroprotective Effects ◽  
Non Invasive ◽  
Retinal Pathology ◽  
Resolution Imaging

Optical coherence tomography (OCT) has emerged as a fast, non-invasive, inexpensive, high-resolution imaging technique in multiple sclerosis (MS). Retinal layer quantification by OCT facilitates a ‘window’ into not only local retinal pathology but also global neurodegenerative processes, recognised to be the principal substrates of disability accumulation in MS. While OCT measures in MS have been demonstrated to reflect visual function, inflammatory activity outside of the visual pathways, disability measures including the prediction of disability progression, whole brain atrophy, and the differential neuroprotective effects of disease-modifying therapies, debate continues regarding the clinical utility of OCT in everyday practice. This review presents an overview of the evidence supporting OCT, with particular focus on its application in the MS clinic. We will also discuss the role of OCT in MS clinical trials to develop novel neuroprotective and potential remyelinating therapies.

scholarly journals Optical Coherence Tomography and Visual Evoked Potentials as Prognostic and Monitoring Tools in Progressive Multiple Sclerosis

2021 ◽  
Vol 15 ◽  
Author(s):  
Simone Guerrieri ◽  
Giancarlo Comi ◽  
Letizia Leocani
Keyword(s):  
Multiple Sclerosis ◽  
Optical Coherence Tomography ◽  
Evoked Potentials ◽  
Visual Evoked Potentials ◽  
Structural Damage ◽  
Progressive Multiple Sclerosis ◽  
Optical Coherence ◽  
Technological Advances ◽  
Visual Evoked

Understanding the mechanisms underlying progression and developing new treatments for progressive multiple sclerosis (PMS) are among the major challenges in the field of central nervous system (CNS) demyelinating diseases. Over the last 10 years, also because of some technological advances, the visual pathways have emerged as a useful platform to study the processes of demyelination/remyelination and their relationship with axonal degeneration/protection. The wider availability and technological advances in optical coherence tomography (OCT) have allowed to add information on structural neuroretinal changes, in addition to functional information provided by visual evoked potentials (VEPs). The present review will address the role of the visual pathway as a platform to assess functional and structural damage in MS, focusing in particular on the role of VEPs and OCT, alone or in combination, in the prognosis and monitoring of PMS.

The role of optical coherence tomography in multiple sclerosis: Expert panel consensus

2007 ◽  
Vol 263 (1-2) ◽  
pp. 3-14 ◽  
Author(s):  
Robert C. Sergott ◽  
Elliot Frohman ◽  
Robert Glanzman ◽  
Ahmad AL-Sabbagh
Keyword(s):  
Multiple Sclerosis ◽  
Optical Coherence Tomography ◽  
Expert Panel ◽  
Optical Coherence
Sign in / Sign up

Export Citation Format

Share Document