scholarly journals Study of the effect of treatment with pomegranate peel extract on the microbial load of coated Awassi lambs' meat samples when preserved by freezing: دراسة تأثير المعاملة بمستخلص قشور الرّمان على الحمولة الميكروبية لعينات لحم حملان العواس المغلّفة عند حفظها بالتجميد

2021 ◽  
Vol 5 (4) ◽  
pp. 104-91
Author(s):  
Raeed Ahmad Al-Hamed, Nuha Shehadeh Al-Ali, Fateh Mamdouh Ab Raeed Ahmad Al-Hamed, Nuha Shehadeh Al-Ali, Fateh Mamdouh Ab
Keyword(s):  
Anaerobic Bacteria ◽  
Storage Period ◽  
Microbial Load ◽  
Pomegranate Peel ◽  
E Coli ◽  
Pomegranate Peel Extract ◽  
Number Of Bacteria ◽  
Peel Extract ◽  
Control Samples ◽  
Awassi Lambs

  In this study, the effect on the microorganism counts and the changes of this microbial load on the meat of Awassi lambs were studied after being packed and stored for 6 months under freezing conditions (-18 C) through treatment with pomegranate peel extract. The research tests were conducted in the laboratories of the Food Science Department at the Faculty of Agricultural Engineering in Deir Ezzor. The results of the microbial load counts showed significant differences in the numbers of intermediate thermophilic anaerobic bacteria between the samples treated with the extract and the control samples during the storage period. Significant differences were also observed in the numbers of E. coli bacteria, and the samples treated with concentration (1.5%) were the least numbered compared to samples treated with other concentrations. The average logarithm of the numbers of E. coli bacteria in the meat of Awassi lambs decreased from (7.74, 7.45, 6.64) in The beginning of the storage period to (3.72, 2.54, 1.21) at the end, when using pomegranate peel extract concentrations (0.5, 1, 1.5%) respectively. The average logarithm of the number of bacteria Pseudomonas according to the concentration of the extract (0.5%, 1%, 1.5%) from (11.07, 11.02, 10.46) at the beginning of the storage period to (7.12, 6.23, 2.98) at the end of the storage period, respectively, as for the control samples. (Other than the treatment with the extract), the number of bacteria increased in an insignificant way.

scholarly journals Effect of Chitosan–Pullulan Composite Edible Coating Functionalized with Pomegranate Peel Extract on the Shelf Life of Mango (Mangifera indica)

Coatings ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 764
Author(s):  
Nishant Kumar ◽  
Pratibha ◽  
Neeraj ◽  
Anka Trajkovska Petkoska ◽  
Sawsan Ali AL-Hilifi ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Shelf Life ◽  
Mangifera Indica ◽  
Storage Period ◽  
Edible Coating ◽  
Postharvest Quality ◽  
Pomegranate Peel ◽  
Preservation Method ◽  
Pomegranate Peel Extract ◽  
Peel Extract

The polysaccharide based composite biomaterial (coating) used in preserving fruits and vegetables during storage is attracting increased attention as it is biodegradable material that prolongs shelf life. In the present investigation, chitosan–pullulan (50:50) composite edible coating was prepared with pomegranate peel extract (0.02 g/mL) as an active antioxidant agent. The effect of treatment with pomegranate peel extract enriched chitosan–pullulan composite edible coating on the shelf life of mango fruits during 18 days of storage period at room (23 °C) and cold (4 °C) temperature was evaluated. Results of the present study demonstrated that the application of chitosan–pullulan composite edible coating significantly (p ≤  0.05) influences the storage life of mango fruits at both storage temperatures. The chitosan–pullulan composite edible coating reduced the physiological loss in weight (PLW), and maintained total soluble solids (TSS), acidity and pH of coated mango fruits as compared to the control. In addition, fruit sensory quality such as freshness, color, taste and texture were also retained by the treatment. Furthermore, sustained firmness, phenolic content and antioxidant activity confirmed the effectiveness of the pomegranate peel extract enriched chitosan–pullulan composite edible coating on mango fruits. The phenolic, flavonoid and antioxidant activity of coated fruits were retained by pomegranate peel rich edible coating. Therefore, the chitosan–pullulan (50:50) combination with pomegranate peel extract can be used as an alternative preservation method to prolong the shelf life of mango fruits at room and cold storage conditions. However, more in-depth studies are required at farm and transit level without affecting the postharvest quality of mango fruits, providing more revenue for farmers and minimizing postharvest losses.

scholarly journals Pomegranate Peel Extract Alters the Microbiome in Mice and Dysbiosis Caused by Citrobacter Rodentium Infection (P20-043-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Nadja George ◽  
Lumei Cheung ◽  
Devanand Luthria ◽  
Monica Santin ◽  
Harry Dawson ◽  
...  
Keyword(s):  
Post Infection ◽  
Agricultural Research ◽  
Enteric Bacteria ◽  
Rrna Gene ◽  
Citrobacter Rodentium ◽  
Microbial Composition ◽  
Pomegranate Peel ◽  
E Coli ◽  
Pomegranate Peel Extract ◽  
Peel Extract

Abstract Objectives We previously showed that a pomegranate peel extract (PPX) reduced the pathogenicity of a Citrobacter rodentium (Cr) infection, an E. coli-like organism that infects mice and mimics many aspects of pathogenic E coli infections in humans. The purpose of this study was to evaluate the effect of PPX on the microbiome of uninfected and Cr-infected mice to determine if changes to the microbiome was associated with reduced pathogenicity. Methods To evaluate the effect of PPX on the microbiome, mice were treated with water or PPX for 14 days and feces collected for analysis. In a second experiment, mice were treated with PPX for 14 days, feces collected, the mice infected with Cr and feces collected again at day 6 post-infection. Colon tissue was collected at day 12 post-infection for determining Cr load and histological analyses. DNA was isolated from the fecal samples and subjected to 16S rRNA gene sequencing to determine the microbial composition. Results PPX treatment decreased the extent of Cr-induced colon damage. Differences in the composition of the microbiome were observed for untreated and PPX-treated mice with PPX mice having decreased diversity. PPX treatment decreased the Firmicutes/Bacteroidetes ratio by increasing Bacteroidetes and decreasing Firmicutes levels. The decrease in Firmicutes was driven by a large reduction in Lactobacillus. PPX-treatment increased the abundance of Proteobacteria and Verrucomicrobiae and decreased Actinobacteria. The relative abundance of Cr reached 22% in water-treated but only 5% in PPX-treated infected mice while the absolute numbers of Cr were similar between the two groups and this may have contributed to the reduced pathology in PPX-treated Cr-infected mice. Conclusions PPX-treatment altered the microbiome making it more resistant to displacement by infection with Cr, thus reducing the percentage of the total microbiome that Cr occupied and this correlated with reduced colon pathology. These results show that the pomegranate peel contains compounds that have the potential to alter the host microbiome and pathology induced by an important class of food-borne enteric bacteria. Funding Sources USDA Agricultural Research Service.

scholarly journals The antioxidant, antimicrobial, and clinical effects with elemental contents of Pomegranate (Punica Granatum) Peel Extraction: A Review

2021 ◽  
Vol 2 (01) ◽  
pp. 21-28
Author(s):  
Abdul Qahir ◽  
Attiq-Ur-Rehman Kakar ◽  
Naqeebullah Khan ◽  
Samiullah ◽  
Abdul Hakeem ◽  
...  
Keyword(s):  
Punica Granatum ◽  
Salmonella Typhi ◽  
Vital Role ◽  
Klebsiella Pneumonia ◽  
Clinical Effects ◽  
Pomegranate Peel ◽  
E Coli ◽  
Deciduous Shrubs ◽  
Pomegranate Peel Extract ◽  
Peel Extract

Background: Pomegranate belongs to the family of Punicaceae. It has deciduous shrubs. Pomegranate is generally cultivated in Afghanistan, China, Iran, India, Pakistan, USA. Objective: This study aimed to review the pomegranate peels for exploring their importance in the field of health. Results: This review showed that Pomegranate is used as food and plays a vital role in the medicinal field. Because pomegranate fruit and its peel extraction contain various compounds like antioxidants, phenolic Acid, Flavonoids, Tannins etc., that have been found very effective in the health field. Due to the presence of antioxidants and other active compounds, pomegranates' peel is imperative for the betterment of human health. Besides, various medicines such as antidiarrheal medicine may be prepared from the peel extract of Pomegranate. Peel extract can act against various microbes such as Klebsiella pneumonia and Staphylococcus epidermidis, Bacillus subtilis, Klebsiella pneumoniae, Salmonella typhi, E. coli, S. aureus etc. The pomegranate strip and root remove have been accounted for in creatures to diminish blood glucose activity. Conclusion: It concludes that further research is needed to explore the hidden characteristics of pomegranate peel.

Preparation and Biochemical Evaluation of Functionalized Multi-Walled Carbon Nanotubes with Punica granatum Extract

2019 ◽  
Vol 15 (1) ◽  
pp. 138-144 ◽  
Author(s):  
Ahmed A. Haroun ◽  
Abdel-Tawab H. Mossa ◽  
Samia M.M. Mohafrash
Keyword(s):  
Liver Enzymes ◽  
Histopathological Analysis ◽  
Pomegranate Peel ◽  
Liver And Kidney ◽  
Multi Walled Carbon Nanotubes ◽  
Pomegranate Peel Extract ◽  
Walled Carbon Nanotubes ◽  
Functionalized Mwcnts ◽  
Peel Extract

Background: Funcionalized multi-walled carbon nanotubes (ox-MWCNTs) were used for the preparation of therapeutic nanoparticles for delivery of some bioactive compounds. Consequently, this work deals with the preparation of grafted MWCNTs with n-vinyl caprolactam in the presence of pomegranate peel extract (P. granatum), titanium dioxide (TiO2) and/or silver nanoparticeles and their toxic effects on male mice using in vivo biological examination (liver and kidney dysfunction biomarkers) and the histopathological analysis. Methods: P. granatum extract was immobilized onto functionalized MWCNTs using simple adsorption technique. Moreover, The prepared materials were analyzed by Fourier transform infrared spectroscopy (FTIR), scanning electron microscope (SEM). In vivo examination using liver and kidney dysfunction biomarkers was investigated. In addition, the histopathological study was carried out. Results: The ox-MWCNTs induced significant elevation in the liver enzymes including AST, ALT and ALP relative to the control group. While, the treatment with P. granatum extract only did not induce any change in the liver and kidney biomarkers. In other words, P. granatum extract loaded onto functionalized MWCNTs showed low effects on liver enzymes and kidney function biomarkers in the treated mice in comparison with ox-MWCNTs and extract separately. Moreover, histopathological analysis revealed that the P. granatum extract functionalized MWCNTs exhibited normal renal tissue with no histopathological alteration. Conclusion: The grafted MWCNTs with n-vinyl caprolactam in the presence of pomegranate peel extract (P. granatum), titanium dioxide (TiO2) and/or silver nanoparticeles were successfully prepared. SEM-micrographs showed complete coating of MWCNTs fiber with the extract. The prepared materials resulted in no toxic effects and the histopathological findings were confirmed by inflammation of the liver and kidney tissues.

Sargassum fusiforme together with turmeric extract and pomegranate peel extract alleviates obesity in high fat-fed C57BL/6J mice

2021 ◽  
Author(s):  
Sainan Zhou ◽  
Qing Zhang ◽  
Yuan Gao ◽  
Fang Liu ◽  
Wanxiu Cao ◽  
...  
Keyword(s):  
Intestinal Flora ◽  
Obese Mice ◽  
High Fat ◽  
Pomegranate Peel ◽  
Fat Accumulation ◽  
Sargassum Fusiforme ◽  
Turmeric Extract ◽  
Pomegranate Peel Extract ◽  
Peel Extract

Sargassum fusiforme together with the turmeric extract and pomegranate peel extract may effectively reduce fat accumulation and improve the disorder of intestinal flora in obese mice.

scholarly journals Pomegranate Peel Extract Is a Potential Alternative Therapeutic for Giardiasis

Antibiotics ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 705
Author(s):  
Asmaa M. El-Kady ◽  
Iman A. M. Abdel-Rahman ◽  
Samer S. Fouad ◽  
Khaled S. Allemailem ◽  
Taghrid Istivan ◽  
...  
Keyword(s):  
Diarrheal Disease ◽  
Apoptotic Cell ◽  
In Vitro Study ◽  
Ethanolic Extract ◽  
Control Group ◽  
Pomegranate Peel ◽  
Pomegranate Peel Extract ◽  
Multiple Drugs ◽  
Peel Extract

Giardiasis is a major diarrheal disease affecting approximately 2.5 million children annually in developing countries. Several studies have reported the resistance of Giardia lamblia (G. lamblia) to multiple drugs. Therefore, identifying an effective drug for giardiasis is a necessity. This study examined the antiparasitic effect of Punica granatum (pomegranate) and evaluated its therapeutic efficacy in rats infected with G. lamblia. In vitro study showed high efficacy of pomegranate peel ethanolic extract in killing G. lamblia cysts as demonstrated by eosin vital staining. We showed that treating infected rats with pomegranate extract resulted in a marked reduction in the mean number of G. lamblia cysts and trophozoites in feces and intestine respectively. Interestingly, the number of G. lamblia trophozoites and cysts were significantly lower in the pomegranate extract-treated group compared to the metronidazole-positive control group. Moreover, pomegranate extract treatment significantly induced nitric oxide (NO) and reduced serum IL-6 and TNF-α, compared to infected untreated rats. Histological and scanning electron microscopy (SEM) examination of the jejunum and duodenum of pomegranate extract-treated animals confirmed the antiparasitic effect of the extract, and demonstrated the restoration of villi structure with reduction of villi atrophy, decreased infiltration of lymphocytes, and protection of intestinal cells from apoptotic cell death. In conclusion, our data show that the pomegranate peel extract is effective in controlling G. lamblia infections, which suggests that it could be a viable treatment option for giardiasis.

scholarly journals Pomegranate Peel Extract Polyphenols Attenuate the SARS-CoV-2 S-glycoprotein Binding Ability to ACE2 Receptor: In Silico and In Vitro Studies

2021 ◽  
pp. 105145
Author(s):  
Relja Suručić ◽  
Maja Travar ◽  
Miroslav Petković ◽  
BiljanaTubić ◽  
Miloš P. Stojiljković ◽  
...  
Keyword(s):  
In Silico ◽  
In Vitro Studies ◽  
Pomegranate Peel ◽  
Binding Ability ◽  
Pomegranate Peel Extract ◽  
Peel Extract

scholarly journals Breast cancer drug delivery by novel drug-loaded chitosan-coated magnetic nanoparticles

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
A. Taherian ◽  
N. Esfandiari ◽  
S. Rouhani
Keyword(s):  
Breast Cancer ◽  
Magnetic Nanoparticles ◽  
Free Drug ◽  
Pomegranate Peel ◽  
Vast Number ◽  
Therapeutic Method ◽  
Cytotoxicity Studies ◽  
Pomegranate Peel Extract ◽  
Novel Drug ◽  
Peel Extract

Abstract Background Breast cancer is one of the most challenging cancers among women which is considered one of the most lethal cancers to this date. From the time that cancer has been discovered, finding the best therapeutic method is still an ongoing process. As a novel therapeutic method, nanomedicine has brought a vast number of materials that could versatilely be used as a drug carrier. The purpose of this study is to develop a novel black pomegranate peel extract loaded with chitosan-coated magnetic nanoparticles to treat breast cancer cells. Results The morphology and size distribution of the nanoparticles studied by dynamic light scattering, atomic force microscopy, scanning, and transitional electron microscopy showed the spherical shape of the nanoparticles and their promising size range. Studies by Fourier transform infrared spectroscopy, X-ray diffraction, vibrating sample magnetometer, and zeta sizer confirmed the synthesis, substantial crystallinity, magnetic potential of the nanoparticles, and their satisfactory stability. The DPPH assay revealed that the obtained black pomegranate peel extract has 60% free radical scavenging activity. The cytotoxicity studies by MTT and LDH assay carried out on NIH/3T3, MBA-MB-231, and 4T1 cells confirmed that the magnetic nanoparticles had no significant cytotoxicity on the cells. However, the drug-loaded nanoparticles could significantly eradicate cancerous cells which had more efficiency comparing to free drug. Furthermore, free drug and drug-loaded nanoparticles had no toxic effect on normal cells. Conclusion Owing to the results achieved from this study, the novel drug-loaded nanoparticles are compatible to be used for breast cancer treatment and could potentially be used for further in vivo studies.

Sign in / Sign up

Export Citation Format

Share Document