Association between BMI, waist circumference and prehypertension among adults

2021 ◽  
Vol 28 (05) ◽  
pp. 697-701
Author(s):  
Ahmed Murtaz Khalid ◽  
Iffat Naiyar ◽  
Rizwan Masud ◽  
Aiman Farogh Anjum ◽  
Fatima Kamran ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Waist Circumference ◽  
Intervention Strategy ◽  
Normal Weight ◽  
Morbidly Obese ◽  
Correlational Study ◽  
Anthropometric Parameters ◽  
Set Up ◽  
Study Setting

Objective: To know the association between different anthropometric parameters for overweight and obese individuals to prevalence of prehypertension. Study Design: Correlational study. Setting: Vicinity of Kharian and at Outpatient Department, CMH Kharian Cantt. Period: February 2019 and January 2020. Material & Methods: Correlational study carried out in the vicinity of Kharian by employing different anthropometric measurements in accordance with guidelines to look at how blood pressure figure behaves in overweight, obese and morbidly obese population and further is there a difference in overall outcome if we use waist circumference rather than BMI and its significance in targeting preventive strategies. Results: Our results show a staircase pattern of increase in blood pressure, initially lying in different phases of prehypertension among normal weight (BMI 23±1.65; waist circumference (WC): 86.45±8.78; Systolic BP:127±11.99; Diastolic BP:80.44 ±9.45), overweight (BMI 27.35 ±1.23; WC:100±5.32; Systolic BP:128.72 ±11.29; Diastolic BP:80.05 ±6.66) and obese individuals (BMI 31.97 ±1.45; WC:112.12±9.22; Systolic BP:138.06 ±21.61; Diastolic BP:87.56 ±9.78), while this trend shifted to full blown hypertension among morbidly obese individuals (BMI 39.88 ±4.30; WC:120.38±12.84; Systolic BP:145 ±17.64; Diastolic BP:89.23 ±10.95) Conclusion: We conclude that prehypertension is already prevalent among normal weight and overweight individuals, and intensive follow up and lifestyle intervention strategy should be employed earlier at this level and waist circumference is a better predictor of cardiovascular disease than BMI and should be routinely done in local primary health care set up to prevent the onset of complications associated with this silent killer.

Cross-talk between ANGPTL4 gene SNP rs1044250 and weight management is a risk factor of Mets

2020 ◽  
Author(s):  
Zhoujie Tong ◽  
Jie Peng ◽  
Hongtao Lan ◽  
Wenwen Sai ◽  
Yulin Li ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Risk Factor ◽  
Waist Circumference ◽  
Weight Management ◽  
Independent Risk Factor ◽  
Lifestyle Changes ◽  
Elevated Blood Pressure ◽  
Base Line ◽  
Elevated Blood

Abstract Background The prevalence of metabolic syndrome (Mets) is closely related to the increased incidence of cardiovascular events. Angiopoietin-like protein 4 (ANGPTL4) is contributory to the regulation of lipid metabolism, herein, may provide a target for gene-aimed therapy of Mets. This case-control study was designed to elucidate the relationship between Angiopoietin-like protein 4 (ANGPTL4) gene single nucleotide polymorphism (SNP) rs1044250 and the onset of Mets, and to explore the effect of interaction between SNP rs1044250 and weight management on Mets. Methods We have recruited 1018 Mets cases and 1029 controls in this study. The SNP rs1044250 was detected, base-line information and Mets-related indicators were collected. A 5-year follow-up survey was carried out to track the lifestyle changes, drug treatments and changes in Mets-related indicators. Results ANGPTL4 gene SNP rs1044250 is an independent risk factor for increased waist circumference (OR 1.618, 95% CI [1.119–2.340]; p = 0.011) and elevated blood pressure (OR 1.323, 95% CI [1.002–1.747]; p = 0.048), the prevalence of Mets (OR 1.875, 95% CI [1.363–2.580]; p < 0.001) is increased. The follow-up survey shows that rs1044250 CC genotype patients with weight gain have an increased number of Mets components (M [Q1, Q3]: CC 1 (0, 1), CT + TT 0 [-1, 1]; p = 0.021); The interaction between SNP rs1044250 and weight management is a risk factor for increased SBP (β = 0.075, p < 0.001) and increased DBP (β = 0.097, p < 0.001), the synergistic effect is negative (S < 1). Conclusion ANGPTL4 gene SNP rs1044250 is an independent risk factor for increased waist circumference and elevated blood pressure, therefore, for Mets. Weight management that interacts negatively with ANGPTL4 polymorphism is an essential lifestyle intervention approach for elevated blood pressure.

Blood pressure among children and adolescents with normal weight but large waist circumference in Shandong, China

2013 ◽  
Vol 173 (3) ◽  
pp. 285-289 ◽  
Author(s):  
Zhang Ying-xiu ◽  
Sun Da-yong ◽  
Zhou Jing-yang ◽  
Zhao Jin-shan ◽  
Chu Zun-hua
Keyword(s):  
Blood Pressure ◽  
Waist Circumference ◽  
Children And Adolescents ◽  
Normal Weight

Gender Differences in Cardiometabolic Risk Factors in Metabolically Healthy Normal Weight Adults with Central Obesity

2017 ◽  
Vol 126 (05) ◽  
pp. 309-315
Author(s):  
Katarína Šebeková ◽  
Melinda Csongová ◽  
Radana Gurecká ◽  
Zora Krivošíková ◽  
Jozef Šebek
Keyword(s):  
Blood Pressure ◽  
Waist Circumference ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Central Obesity ◽  
Cross Sectional Study ◽  
Normal Weight ◽  
Cross Sectional ◽  
Fasting Plasma ◽  
Metabolically Healthy

AbstractWe investigated whether metabolically healthy normal weight adults with central obesity display worse cardiometabolic profile compared with their centrally lean counterparts. This retrospective, cross-sectional study, comprised 1 135 subjects (64% females) aged 18-to-81 years, presenting ≤2 components of metabolic syndrome. They were classified as centrally lean (waist-to-height ratio (WHtR)<0.5 and waist circumference<80 cm in females and<94 cm in males) or presenting central obesity (WHtR ≥0.5, regardless of waist circumference). Data on blood pressure, glucose homeostasis, lipid profile, renal function, high-sensitive C-reactive protein (hsCRP), uric acid, adiponectin, leptin, and soluble receptor for advanced glycation end products were compared between the groups, separately in males and females. 5.7% of males and 6.9% of females presented WHtR ≥0.5. Compared with centrally lean subjects, those with central obesity had higher BMI-adjusted fasting plasma glucose (p<0.001), and leptin levels (p<0.05); females also presented higher blood pressure (p<0.001), while males had higher hsCRP concentrations (p=0.021). These changes associated with significantly higher BMI-adjusted odds to present fasting plasma glucose >5.6 mmol/l in both genders, higher odds to present hsCRP >3 mg/l in males, and those to present elevated blood pressure in females. Our analysis suggests that in metabolically healthy normal weight subjects WHtR ≥0.5 might indicate “early increased health risk”.

scholarly journals Children with type 1 diabetes have elevated high sensitivity C-reactive protein compared to a control group

2020 ◽  
Author(s):  
Pilar Pérez-Segura ◽  
Olaya de Dios ◽  
Leticia Herrero ◽  
Claudia Vales-Villamarín ◽  
Isabel González-Aragón ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Waist Circumference ◽  
High Sensitivity ◽  
Control Group ◽  
Z Score ◽  
C Reactive Protein ◽  
Anthropometric Parameters ◽  
Reactive Protein

Abstract Objectives To compare high sensitivity C-reactive protein (hsCRP) levels in children with type 1 diabetes, healthy controls, and children with obesity. Additionally, we aimed to analyze the association between hsCRP levels and glycemic control measured by glycohemoglobin A (HbA1c) and anthropometric and biochemical variables. Methods We conducted a non-randomized descriptive study of children with type 1 diabetes matched for sex and age with a control group and group with obesity. We recorded anthropometric parameters and studied variables related to diabetes, blood pressure, lipid profile, and HbA1c. HsCRP was measured by ELISA.Results We included 49 children with type 1 diabetes, 46 controls, and 40 children with obesity. hsCRP levels were significantly higher in the group with type 1 diabetes compared to controls and nearly significantly lower than in the group comprising children with obesity. We found no correlation between hsCRP and HbA1C and characteristics of type 1 diabetes with the exception of albuminin creatinine ratio (ACR). Statistically significant association was found between hsCRP and BMI and waist circumference Z-score. Conclusions Children with type 1 diabetes have a higher hsCRP than healthy subjects; this difference is not associated with HbA1c, but is related to waist circumference, BMI, and ACR. Obesity prevention should be a priority when performing follow-up in children with type 1 diabetes.

Self-Selected and Prescribed Intensity Exercise to Improve Physical Activity Among Inactive Retirees

2018 ◽  
Vol 40 (9) ◽  
pp. 1301-1318 ◽  
Author(s):  
Zhinan Yang ◽  
Marcia A. Petrini
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
Waist Circumference ◽  
Negative Affect ◽  
Controlled Study ◽  
Daily Step ◽  
Exercise Programs ◽  
Exercise Interventions ◽  
Step Counts

A randomized controlled study explored the effects of two intensity-oriented exercise interventions on affect to exercise and physical activity behavior. Inactive retirees finished the 12-week group-based exercise intervention and 3-month telephone follow-up with 27 in self-selected intensity group and 26 in prescribed intensity group. Repeated measures of daily step counts (measured by Yamax pedometers), positive and negative affect to exercise, weight, height, waist circumference, and blood pressure were done at baseline, postintervention, and 3-month follow-up. Increased daily step counts and positive affect, and reduced body mass index, waist circumference, blood pressure of both groups, and negative affect of self-selected intensity group were found at different measuring times. Although self-selected intensity group had no significantly different daily step counts from prescribed intensity group, the former had a more positive and less negative affect to exercise. Findings suggest that future exercise programs use self-selected intensity exercise programs to improve pleasure affect to exercise.

scholarly journals Changes in lipid profile and some biochemical parameters in postmenopausal women treated with honey

2021 ◽  
Vol 7 (1) ◽  
pp. 31-36
Author(s):  
E C Ogbodo ◽  
B N Ugorji ◽  
S C Meludu ◽  
I S I Ogbu ◽  
L O Egejuru ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Waist Circumference ◽  
Lipid Profile ◽  
Postmenopausal Women ◽  
Biochemical Parameters ◽  
Research Subjects ◽  
Anthropometric Parameters ◽  
Baseline Values ◽  
The Difference ◽  
Natural Honey

The study investigated the effect of natural honey on the lipid profile and some biochemical parameters among postmenopausal women, aged 45-65 years old. Sixty healthy postmenopausal women were given 20 g/day of natural honey and followed up for three months. The primary outcome was changes from baseline on the lipid profile and the chosen biochemical parameters (fasting blood sugar, serum calcium) and some anthropometric parameters. Paired t-test was performed to evaluate the difference between the baseline and the 3 month values of the parameters and lipid profiles. Sixty postmenopausal women successfully completed the study. The result showed that there were significant increases in HDL-C, calcium and significant decreases in LDL-C, TG, TC, and FBS concentrations in the blood of the research subjects after three months of treatment with honey compared with the values at baseline (p&#60;0.05). Also there were significant decreases in the blood pressure, weight and waist circumference of the postmenopausal women after treatment when compared with baseline values (p&#60;0.05). Natural honey helps in improving the lipid profile, FBS, Blood pressure, weights and waist circumference of postmenopausal women and can be included as part or alternative remedies in management of postmenopausal conditions.

Abstract P327: Risk Factors for Prehypertension in the Community

Circulation ◽  
2013 ◽  
Vol 127 (suppl_12) ◽  
Author(s):  
Lisa Rafalson ◽  
Richard P Donahue ◽  
Saverio Stranges
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
New York ◽  
Weight Gain ◽  
Waist Circumference ◽  
General Population ◽  
Population Based ◽  
Health Study ◽  
Increased Risk

Background: Prehypertension is an increasingly highly prevalent condition in the general population, and is associated with an increased risk for coronary heart disease and stroke. However, evidence from population-based studies of the risk factors for prehypertension is scant. We sought to examine the predictors of progression from normotension to prehypertension in a community-based population from Western New York. Methods: We conducted a longitudinal analysis, over six years of follow-up, among 569 men and women (51.8 years, 96% White, 70% female) who were free of prehypertension, hypertension, cardiovascular disease and type 2 diabetes at the baseline examination, in the Western New York Health Study (WNYHS). Incident prehypertension at follow-up was defined as systolic blood pressure of 120-139 mmHg and/or diastolic blood pressure of 80-89 mmHg. Results: In bivariate analyses, there were several correlates of incident prehypertension, including age, BMI and waist circumference, impaired fasting glucose (IFG), uric acid, and baseline blood pressure levels. After multivariate adjustment, IFG at baseline odds ratio (OR):1.69, 95%CI:1.06-2.67) and weight gain since age 25 (OR: 1.28, 1.11-1.58 per 10 lb. increase) were the strongest significant predictors of prehypertension at follow-up. Neither waist circumference nor current BMI were predictor variables in models when they were substituted for weight gain. Conclusions: Results from this study suggest early dysregulation of glucose metabolism and weight gain over the lifespan are likely to represent important risk factors for prehypertension in the general population.

DO BIOMARKERS VARY BY SOCIAL CLASS, EDUCATION AND REGION AND IS MIGRATION IMPORTANT? EVIDENCE FROM A COHORT OF BRITISH ADULTS

2018 ◽  
Vol 51 (1) ◽  
pp. 95-117
Author(s):  
Monika Krzyżanowska ◽  
C. G. Nicholas Mascie-Taylor
Keyword(s):  
Blood Pressure ◽  
Social Class ◽  
Waist Circumference ◽  
Forced Expiratory Volume ◽  
Social Classes ◽  
National Child Development Study ◽  
Regional Mobility ◽  
Region Of Residence ◽  
Important Evidence

SummaryThe aim of this study was to test whether Body Mass Index (BMI), waist circumference, systolic and diastolic blood pressure, Forced Expiratory Volume (FEV1) and Peak Expiratory Flow (PEF) vary in relation to social class at birth and adulthood, educational level and region of residence, and also with inter-generational social, educational and regional mobility/migration. The study used 5702 adults (2894 males and 2718 females) from the longitudinal British National Child Development Study (all children born in England, Scotland and Wales during the first week in March 1958 with follow-up throughout childhood and adulthood, most recently at 55 years of age). In both sexes BMI and waist circumference tended to increase from social classes I+II to IV+V and higher social class was associated with higher mean FEV1 and PEF. Better-educated adults tended to have lower BMI and waist circumference, and higher mean FEV1 and PEF. Women from Wales had the highest mean BMI and waist circumference but the lowest mean PEF, while women in Scotland had the highest mean systolic blood pressure and the lowest mean FEV1. For men only, FEV1 and PEF showed regional variation and the lowest mean FEV1 was in Wales and the lowest PEF in Yorkshire & Humberside. Inter-generational social mobility was not found to be associated with any of the biomarkers, while educational mobility was related only to FEV1 and PEF. In both sexes, in unadjusted regression analysis regional migrant cohort members tended to have a lower mean BMI than sedentes. Regional male migrants also tended to have a lower waist circumference and a higher FEV1 and PEF than sedentes.

scholarly journals Sustained effects of recombinant GH replacement after 7 years of treatment in adults with GH deficiency

2006 ◽  
Vol 155 (5) ◽  
pp. 701-708 ◽  
Author(s):  
A A van der Klaauw ◽  
J A Romijn ◽  
N R Biermasz ◽  
J W A Smit ◽  
J van Doorn ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Gh Deficiency ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Short Term ◽  
Anthropometric Parameters ◽  
Beneficial Effects ◽  
Gh Replacement

Context: The goal of GH replacement with recombinant human GH (rhGH) is to ameliorate symptoms, signs, and complications of adult GH deficiency (GHD) in the long term. To determine whether the observed short-term beneficial effects of rhGH treatment are sustained in the long term, we evaluated biochemical and anthropometric parameters after 7 years of rhGH replacement. Patients and methods: After 2, 5, and 7 years of rhGH replacement, 63 adult GHD patients (30 men, 52 adult-onset GHD) were assessed. IGF-I increased during rhGH replacement, and a stable dose of rhGH was reached within 1 year of rhGH substitution. Thereafter, this individualized dose was continued. Results: Plasma levels of total cholesterol and low-density lipoprotein cholesterol decreased even after 5 years of rhGH replacement (11% decrease, P < 0.001; 22% decrease, P < 0.001 respectively). High-density lipoprotein cholesterol levels increased during 7 years of rhGH replacement (1.4 ± 0.5 mmol/l at baseline vs 1.7 ± 0.5 mmol/l after 7 years, P < 0.001), whereas triglyceride concentrations remained unchanged. Fasting glucose levels increased during follow-up, mainly during the first 2 years of rhGH replacement (4.4 ± 0.7 mmol/l to 5.0 ± 1.0 mmol/l, P < 0.001). Body mass index increased during follow-up, whereas waist circumference and waist-to-hip ratio remained unchanged. Diastolic blood pressure decreased (P = 0.002), but when patients using antihypertensive medication were excluded this decrease did not reach significance (P = 0.064). Systolic blood pressure remained unchanged. Conclusion: The beneficial effects of rhGH replacement, described after short-term rhGH replacement, are sustained in the long term up to 7 years.

Sign in / Sign up

Export Citation Format

Share Document