scholarly journals Veterinary vaccine development: The helical project

2020 ◽  
Vol 4 (1) ◽  
pp. 042-047
Author(s):  
Dereja Iyasu Angani

Vaccine production process have been fuzzy journey to the public and, in some degrees, to those in the setting. By clearly showing the lengthy and challenging journey of vaccine development process, thereby suggesting the economic and health implication of improper use of veterinary vaccines, the paper tries to add the attention given to infection prevention. Starting from the foundations, the types and requirements of veterinary vaccines are described. The paper concludes with current research and regulatory quos in the topic.

2021 ◽  
Vol 17 (1) ◽  
pp. 75-83
Author(s):  
Vincent P.K. Titanji

Vaccines have been recognized as major and effective tools for the control and eventual elimination of infectious diseases and cancer. This brief review examines vaccine classification and development pipeline as well as recent innovations driving the vaccine development process. Using COVID-19 as an example recent innovation in vaccine development are highlighted. The review ends with a call for intensified efforts to build vaccine production capacity in Cameroon and other other African  countries. Les vaccins ont été reconnus comme des outils majeurs et efficaces pour le contrôle et l’élimination éventuelle des maladies infectieuses et du cancer. Cette brève revue examine la classification et le pipeline de développement de vaccins ainsi que les innovations récentes à l’origine du processus de développement de vaccins. En utilisant COVID-19 comme exemple, les innovations récentes dans le développement de vaccins sont mises en évidence. La revue se termine par un appel à intensifier les efforts pour renforcer les capacités de production de vaccins au Cameroun et dans d’autres pays africains.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Rapeephan R. Maude ◽  
Monnaphat Jongdeepaisal ◽  
Sumawadee Skuntaniyom ◽  
Thanomvong Muntajit ◽  
Stuart D. Blacksell ◽  
...  

Abstract Background Key infection prevention and control measures to limit transmission of COVID-19 include social distancing, hand hygiene, use of facemasks and personal protective equipment. However, these have limited or no impact if not applied correctly through lack of knowledge, inappropriate attitude or incorrect practice. In order to maximise the impact of infection prevention and control measures on COVID-19 spread, we undertook a study to assess and improve knowledge, attitudes and practice among 119 healthcare workers and 100 general public in Thailand. The study setting was two inpatient hospitals providing COVID-19 testing and treatment. Detailed information on knowledge, attitudes and practice among the general public and healthcare workers regarding COVID-19 transmission and its prevention were obtained from a combination of questionnaires and observations. Results Knowledge of the main transmission routes, commonest symptoms and recommended prevention methods was mostly very high (> 80%) in both groups. There was lower awareness of aerosols, food and drink and pets as sources of transmission; of the correct duration for handwashing; recommended distance for social/physical distancing; and about recommended types of face coverings. Information sources most used and most trusted were the workplace, work colleagues, health workers and television. The results were used to produce a set of targeted educational videos which addressed many of these gaps with subsequent improvements on retesting in a number of areas. This included improvements in handwashing practice with an increase in the number of areas correctly washed in 65.5% of the public, and 57.9% of healthcare workers. The videos were then further optimized with feedback from participants followed by another round of retesting. Conclusions Detailed information on gaps in knowledge, attitudes and practice among the general public and healthcare workers regarding COVID-19 transmission and its prevention were obtained from a combination of questionnaires and observations. This was used to produce targeted educational videos which addressed these gaps with subsequent improvements on retesting. The resulting videos were then disseminated as a resource to aid in efforts to fight COVID-19 in Thailand and worldwide.


2018 ◽  
Vol 104 (6) ◽  
pp. 559-563 ◽  
Author(s):  
Jenny Retzler ◽  
Nick Hex ◽  
Chris Bartlett ◽  
Anne Webb ◽  
Sharon Wood ◽  
...  

ObjectiveCongenital cytomegalovirus (cCMV) is the most common infectious cause of congenital disability. It can disrupt neurodevelopment, causing lifelong impairments including sensorineural hearing loss and developmental delay. This study aimed, for the first time, to estimate the annual economic burden of managing cCMV and its sequelae in the UK.DesignThe study collated available secondary data to develop a static cost model.SettingThe model aimed to estimate costs of cCMV in the UK for the year 2016.PatientsIndividuals of all ages with cCMV.Main outcome measuresDirect (incurred by the public sector) and indirect (incurred personally or by society) costs associated with management of cCMV and its sequelae.ResultsThe model estimated that the total cost of cCMV to the UK in 2016 was £732 million (lower and upper estimates were between £495 and £942 million). Approximately 40% of the costs were directly incurred by the public sector, with the remaining 60% being indirect costs, including lost productivity. Long-term impairments caused by the virus had a higher financial burden than the acute management of cCMV.ConclusionsThe cost of cCMV is substantial, predominantly stemming from long-term impairments. Costs should be compared against investment in educational strategies and vaccine development programmes that aim to prevent virus transmission, as well as the value of introducing universal screening for cCMV to both increase detection of children who would benefit from treatment, and to build a more robust evidence base for future research.


2022 ◽  
Vol 3 (2) ◽  
pp. 197-202
Author(s):  
Virna Sulfitri ◽  
Henik Hari Astuti ◽  
Budi Santosa

Community Service is one part of the direct contribution from academics, in this case the Faculty of Economics and Business, Trisakti University to the community. On this occasion the Trisakti University FEB team had the opportunity to provide training on Material Flow Cost Accounting (MFCA) for MSMEs. This training is considered important considering that the understanding of MSME actors in terms of the flow cost of material is still very minimal, so that in the implementation of their business there are still very few who apply it in the production process. This training aims to educate MSME actors in terms of flow cost accounting for the use of their production materials, MSMEs can sort out the types and types of materials to be used so as to increase the effectiveness and efficiency of production to increase sales and business profits. PKM training will be carried out using an online method considering the conditions of the COVID-19 pandemic, which until now has not allowed face-to-face/off-line training. The output of this PKM will be published to the public so that it can provide wider benefits.


2021 ◽  
Vol 44 (2/3) ◽  
pp. 50-67
Author(s):  
Vanja Stojanovic

This study assesses the nature of Canada’s rapid research response through term and keyword bibliometric analysis. The following asks: What are the major areas of COVID-19 rapid research output conducted in Canada during the first five and half months of 2020, and how can the results of this analysis inform future accelerated research efforts toward an effective response to infectious disease emergencies? The results suggest that infection prevention, epidemiology, therapeutics, and public health strategies were among the top-producing research areas in Canada during the onset of the pandemic. Moreover, the analysis reflects gaps in the literature addressing diagnostics and vaccine development.


2021 ◽  
Vol 235 ◽  
pp. 02076
Author(s):  
Yanrong Huang ◽  
Bin Huang ◽  
Min Chen

Crowdsourcing is an important form for enterprises to realize open innovation, which can gather the wisdom of the public and gather talents from various fields to participate in technological innovation and value creation. This paper systematically reviews the emergence and development of crowdsourcing in China, analyzes the causes and characteristics of the four stages of crowdsourcing development with the clue of major events in the development process of crowdsourcing; takes the operation process of crowdsourcing as the breakthrough point, discusses the bidirectional driving optimization path for the benign rolling development of crowdsourcing mode under the background of “mass entrepreneurship and innovation”; and prospects. Finally, the future development direction of crowdsourcing mode is pointed out.


2021 ◽  
Author(s):  
◽  
Lynne Carmichael Allan

<p>The role that the physical environment of an exhibition plays in the visitor's experience of a museum is a topic that, though increasingly acknowledged in museum studies, has not yet received detailed attention from researchers. The interaction of exhibitor and visitor, in and through exhibitions, can be situated in the wider context of the recent paradigm shirt within museum practice, towards communication with the public and developments in museum theory, which consider the qualitative aspects of the visitor experience as an active dialogue, conversation or a process of meaning-making. This dissertation examines the interactive exhibit Stowaways in the permanent exhibition, Blood, Earth, Fire - Whāngai, Whenua, Ahi Kā, at the Museum of New Zealand Te Papa Tongarewa. It considers the question 'How does the physical environment affect the meanings that the visitor makes in and after visiting the exhibition?' The study builds on existing New Zealand research, which questioned the gap between exhibition creation and visitor reception. A theoretical framework was constructed from relevant strands of the literature of museum studies, visitor studies and exhibition design. A qualitative approach was employed, in order to examine in detail both the exhibition development process and then how the visitor responded to the exhibition. Several methods were used to conduct the research, such as archival research and interviews with both the museum staff and seven visitors, who came with their families to the exhibit. The findings provide interesting evidence of the complex and deep affect that the built exhibition space can have on the visitor, not just at the time of the visit but long afterwards. This was an affect that rippled out from the individual to their family group and everyday life. This dissertation makes a small but significant contribution to museum studies in New Zealand, through an integrated examination of the production and reception of a museum exhibit, from the perspective of both the visitor and the museum. One of the main conclusions was to re-iterate the important role of exhibition evaluation in facilitating a more complete communication between museum and visitor, by allowing museum professionals to build on the experience of the development process in a way that can inform future practice.</p>


2018 ◽  
Vol 18 (2) ◽  
pp. 172-199 ◽  
Author(s):  
Cleiton Rodrigues de Vasconcelos ◽  
Daniel Pereira da Silva

The protection of intellectual property (IP) is a crucial area to support the development process of any country, as it is in this context that the biggest strategic disputes are taking place. In recent years Brazil has developed some actions to achieve greater efficiency in the public IP management system, but are we on the right track? The present study seeks to present answers regarding the performance of Brazil and to highlight the advances and challenges regarding the IP system. The methodological approach was structured based on a review in the literature, highlighting the scientific, economic and technological indicators on the development of IP and the main IP objects registered with the Brazilian national intellectual property body (INPI) in the period of 2013 to 2016, in the areas of patents, trademarks, industrial design, computer program, circuit topography, technology contracts and geographical indication.


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