scholarly journals Tolerance to extreme doses of psychoactive substances

2021 ◽  
Vol 5 (1) ◽  
pp. 027-031
Author(s):  
Baitubayеv DG ◽  
Baitubayeva MD
Keyword(s):  
Current Level ◽  
Psychoactive Substances ◽  
Biological Mechanisms

The article shows that the current level of physiology does not disclose the biological mechanisms of the organism’s transition from one range to adapt to a higher one with an increase in the regular forces of the stimulus above sub-extreme. A new trend in the physiology of adaptation - proqredient adaptation, explains the mechanism of increasing the tolerance of the organism, with dependence on psychoactive substances (PAS). Scientific has reasonably shown that depending on the organism from PAS - not the disease, and the states like proqredient adaptation.

scholarly journals Biological Mechanisms of Increasing the Resistance, Physiology of Progredient Adaptation and Validation of the Organism’s Dependence on Psychoactive Substances

2018 ◽  
Vol 2 (2) ◽  
Keyword(s):  
The State ◽  
Current Level ◽  
Psychoactive Substances ◽  
Biological Mechanisms

The article shows that the current level of physiology does not explain the biological mechanisms of the organism transition from one adaptation range to a higher one, with an increase in the strength of the regular stimulus above the sub-extreme level. A new trend in the physiology of adaptation - proqredient adaptation - explains the mechanism of increasing the resistance of the organism with dependence on psychoactive substances (PAS). It is scientifically proved, that dependence of the organism on PAS is not the disease, but the state of proqredient adaptation.

scholarly journals Biology of increased tolerance and validation of the psychoactive substance dependence

2022 ◽  
Vol 5 (1) ◽  
pp. 01-05
Author(s):  
D.G. Baitubayеv
Keyword(s):  
Substance Dependence ◽  
Current Level ◽  
Psychoactive Substance ◽  
Psychoactive Substances ◽  
Biological Mechanisms

The article shows that the current level of physiology does not disclose the biological mechanisms of the organism transition from one range to adapt to a higher with an increase in the regular forces of the stimulus above sub-extreme. A new trend in the physiology of adaptation - proqredient adaptation, explains the mechanism of increasing the tolerance of the organism, with dependence on psychoactive substances (PAS ). It is scientifically proved, that dependences of the organism on PAS are the states of progredient adaptation.

scholarly journals Reasons for increased tolerance and validation of psychoactive substance dependence

2021 ◽  
Vol 6 (11) ◽  
Keyword(s):  
Substance Dependence ◽  
Current Level ◽  
Psychoactive Substance ◽  
Psychoactive Substances ◽  
Biological Mechanisms

The article shows that the current level of physiology does not disclose the biological mechanisms of the organism transition from one range to adapt to a higher with an increase in the regular forces of the stimulus above sub-extreme. A new trend in the physiology of adaptation - proqredient adaptation, explains the mechanism of increasing the tolerance of the organism, with dependence on psychoactive substances (PAS). It is scientifically proved, that dependences of the organism on PAS are the states of progredient adaptation.

Extraversion and Dopamine

1998 ◽  
Vol 3 (1) ◽  
pp. 37-50 ◽  
Author(s):  
Thomas H. Rammsayer
Keyword(s):  
Individual Differences ◽  
D2 Receptor ◽  
D2 Receptors ◽  
Behavioral Differences ◽  
Biological Mechanisms ◽  
Brain Dopamine ◽  
Personality Dimension ◽  
Time Performance ◽  
Reaction Time Performance ◽  
Induced Changes

Recent research suggests that individual differences in brain dopamine (DA) functioning may be related to the personality dimension of extraversion. The present study was designed to further elucidate the biological mechanisms underlying behavioral differences between extraverts and introverts. For this purpose, the differential effects of a pharmacologically induced blockade of mesolimbocortical DA D2 receptors on reaction-time performance were investigated in 24 introverted and 24 extraverted subjects. Introverts were found to be much more susceptible to pharmacologically induced changes in D2 receptor activity than extraverts. This finding provides additional experimental evidence for the notion that individual differences in D2 receptor responsivity may represent a neurobiological substratum for the personality dimension of extraversion.

Biological Mechanisms of Motivation

1987 ◽  
Vol 32 (8) ◽  
pp. 705-706
Author(s):  
James R. Stellar
Keyword(s):  
Biological Mechanisms

The dependence syndrome across different psychoactive substances: Revised DSM-III.

1987 ◽  
Author(s):  
Thomas R. Kosten ◽  
Bruce J. Rounsaville ◽  
Thomas F. Babor ◽  
Robert L. Spitzer
Keyword(s):  
Psychoactive Substances

Production capacity of Russian industry: Potential of import Substitution and economic Growth

2015 ◽  
pp. 5-24 ◽  
Author(s):  
B. Zamaraev ◽  
T. Marshova
Keyword(s):  
Economic Growth ◽  
Import Substitution ◽  
Production Capacity ◽  
Current Level ◽  
High Tech ◽  
Industrial Growth ◽  
Russian Industry ◽  
Technological Modernization ◽  
Capacity Structure ◽  
Idle Capacity

The article examines the state of production capacity of Russian industry. It is shown that in spite of certain positive shifts, the rate of technological modernization in recent years has been insufficient for marked progressive changes in the capacity structure and quality. In contrast to the industrial growth after the crisis of 1998 that took place in the presence of significant reserves of capacity, the current level of idle capacity is much lower. The lack of mass input of modern and high-tech industries objectively limits the possibilities of import substitution and economic growth.

Prospettiva e Valore della matrice Cheratinica nella valutazione dell'utilizzo di Nuove Sostanze Psicoattive nella popolazione che afferisce ai SERD

MISSION ◽  
2020 ◽  
pp. 39-44
Author(s):  
Concettina Varango ◽  
Francesca Musarella ◽  
Mara Cella ◽  
Antonella Varango
Keyword(s):  
Novel Psychoactive Substances ◽  
Psychoactive Substances

Questo articolo nasce dall'esigenza di informare un più ampio pubblico sul pericolo rappresentato da queste sostanze, far conoscere le NPS (Novel Psychoactive substances) agli operatori del settore (personale di laboratorio, personale delle unità di emergenza/ urgenza, operatori sanitari, ricercatori, ecc.) al fine di agevolare l'analisi di campioni sconosciuti e divulgare i dati scientifici che cominciano ad emergere da studi clinici e preclinici sui loro effetti tossici e farmacologici. Dal 2009 sono comparsi nel gruppo delle N.P.S., i nuovi oppioidi sintetici, molecole estremamente potenti che comportano una seria minaccia per la salute pubblica. Si tratta di prodotti dalla notevole potenza (il fentanyl, per esempio, capostipite di questa famiglia, ha un'azione circa 100 volte maggiore rispetto a quella della morfina) che vengono utilizzati sia per sé sia come adulteranti di partite di sostanze classiche, soprattutto eroina, causando scie di decessi per overdose. 

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