scholarly journals Demographic profile & correlation between retinal exudates and hematological parameters in leukemic patients

2021 ◽  
Vol 5 (1) ◽  
pp. 009-014
Author(s):  
Monjur Hasan FM ◽  
Gomes Richmond Ronald
Keyword(s):  
White Cell Count ◽  
Hematological Parameters ◽  
Cross Sectional Study ◽  
P Value ◽  
Retinal Hemorrhages ◽  
Cross Sectional ◽  
Demographic Profile ◽  
Medical College ◽  
Fundoscopic Examination ◽  
Retinal Exudates

Background: Leukemia is frequently associated with fundoscopic abnormalities. However, no organized effort has been made for analyzing leukemic retinopathy in our country. This study was done to observe the demographic profile and correlation between fundoscopic findings of retinal exudates and hematological parameters in leukemic patients. Materials and Methods: The study was a hospital-based descriptive cross-sectional study among 50 leukemic patients in Medicine and Oncology departments of Bangladesh Medical College and Hospital (BMCH) from May, 2020 to October, 2020. Fundoscopic examination was done which was reviewed by an ophthalmologist. Collected data was analyzed statistically by using SPSS-17 (Chicago, Illinois). Results: Among 50 leukemic patients’, the fundal lesion was detected in 32 patients (64%), retinal exudates are rare. Only 3 patients (6%) had exudates while others (29 patients, 58%) have retinal hemorrhages. Exudates did not show any statistically significant relationship with types of leukemia (p value = 0.53). There was no statistically significant association between fundal exudates and high white cell count (p = 0.56) or low hemoglobin level (p = 0.11) or low platelet level (p = 0.11). Conclusion: This study has identified retinopathy occurring frequently in leukemic patients. Therefore, an adequate attention should be paid at fundoscopic evaluation while treating leukemic patients.

scholarly journals A cross sectional study of elderly widows residing in urban field practice area of S. N. Medical College, Bagalkot, Karnataka

2018 ◽  
Vol 5 (12) ◽  
pp. 5224
Author(s):  
Gowri Shankar ◽  
Jayaraj M. Ramachandra ◽  
Sarojini S. Hunshikatti
Keyword(s):  
Cause Of Death ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Chronic Obstructive ◽  
Sectional Study ◽  
Cross Sectional ◽  
Sitting Posture ◽  
Demographic Profile ◽  
Medical College ◽  
Field Practice

Background: Widows are the most vulnerable segment among the elderly population in India. Elderly widows face several social, economic, emotional and cultural deprivations due to their gender, widowhood and old age. Hence, this study was done with the objective to know the socio demographic profile and morbidity of elderly widows residing in urban field practice area of S.N. Medical College, Bagalkot.Methods: This cross sectional study was done in 8 Anganwadi areas during 2016 by cluster random sampling. All the elderly widows residing in the areas were included after informed consent. Ethical clearance was obtained from Institutional review board. Data regarding their socio demographic profile, cause of death of husband, the number of years being a widow, health seeking behavior and their chronic morbidities were noted. Height and weight of each elderly widow was measured and body mass index calculated using the formula weight in kilogram divided by height in meter 2 and classified according to South East Asian category. Blood pressure was recorded three times with the widow in a sitting posture in an interval of 3 minutes and the least value was documented according to JNU classification.Results: Out of 140 elderly widows who were residents of the areas, majority (69.29%) were between 60 to 74 years of age followed by 27.86% between 75 to 89 years of age. It was observed that 75% of them were illiterate. The leading cause of death of husband was coronary heart disease (19.29%), chronic obstructive pulmonary disease (12.86%) and alcoholic cirrhosis (10.71%). On examination of the non-hypertensive widows, it was observed that 36.06% were in Stage I and 22.68% were in Stage II of hypertension (JNU classification).Conclusions: Elderly widows are a vulnerable segment of the community. Their health care needs are a priority and regular health check-ups are to be planned.

scholarly journals THE DEMOGRAPHIC PROFILE OF WOMEN WITH GESTATIONAL DIABETES MELLITUS

2021 ◽  
Vol 5 (11) ◽  
Author(s):  
Priyanka Inaniya ◽  
B S Meena ◽  
Mohan Lal Meena ◽  
Aparna Sharma ◽  
Shalini Rathore
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Family History Of Diabetes ◽  
Demographic Profile ◽  
Medical College ◽  
History Of ◽  
Socio Demographic Factors

Background: The present study aimed to study the demographic profile women with gestational diabetes mellitus Methods: This hospital based cross-sectional study Department of Obstetrics and Gynaecology, SMS Medical College, Jaipur. Results: Mean age of patients was 27.68 ± 4.4 Yrs. Most of the study subjects in GDM group (54.7%) were Hindu. Study subjects in GDM group were almost equally from rural (50.7%).Most of the study subjects in both GDM group (88%) were housewives. Habit of smoking was found in only 6.7% females in GDM group. Habit of alcohol was found in 4% females in GDM group. Family history of diabetes was seen more in females with GDM (17.3%). Conclusion: This study concluded that the socio demographic factors influence the occurrence of GDM. Keywords: GDM, Age, Gravida

Frequency of Metabolic Abnormalities of Vesical Calculus in Children Younger than 10 Yrs of Age

2021 ◽  
Vol 15 (6) ◽  
pp. 1243-1245
Author(s):  
H.U Rahman ◽  
S. F. Shah ◽  
A. J. Sheikh ◽  
I. U. Memon ◽  
W. S. Bhatti ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
P Value ◽  
Metabolic Abnormalities ◽  
Urine Ph ◽  
College Hospital ◽  
Cross Sectional ◽  
Vesical Calculus ◽  
Medical College ◽  
Presenting Symptoms ◽  
Calcium Magnesium

Aim: To assess the metabolic abnormalities in children younger than 10 years of age with vesical calculus. Study design: Retrospective cross-sectional study Place and duration of study: Department of Urology, Khairpur Medical College Hospital, Khairpur from 1st October 2014 to 30th September 2016. Methodology: Two hundred and six children age <10 years of age and either gender presented with vesical calculus were enrolled. Demographic information like age, gender, residence, serum electrolytes, calcium, magnesium, phosphate, uric acid, blood, and urine pH were recorded for the purpose of metabolic workup. Results: The mean age was 4.76±1.22 years and 157 (76.2%) were males and 49 (23.8%) were females. The frequency of metabolic abnormalities was observed in 153 (74.3%) of the patients. A significantly higher prevalence of metabolic abnormalities was observed with male gender (p-value 0.006), dark colored urine as presenting symptoms (p-value 0.022), frequent urination (p-value 0.045), and hematuria (p-value 0.016). Of 153 patients with metabolic abnormalities, hypercalciuria was observed in 45 (29.4%), hypocitraturia in 73 (47.7%), hyperoxaluria in 21 (13.7%), and hyperuricosuria in 14 (9.2%) patients. Conclusion: The frequency of metabolic abnormalities was high among children with vesical calculus. Moreover, hypocitraturia in these children was observed in majority followed by hypercalciuria, hyperoxaluria, and hyperuricosuria. Keywords: Metabolic abnormalities, Children, Vesical calculus

ROLE OF ABSOLUTE EOSINOPHIL COUNT AS A MODALITY OF INVESTIGATION IN SUSPECTED CASES OF HELMINTHIC INFESTATION IN CHILDREN AGED BETWEEN 5 TO 15 YEARS WITH COMPARISON TO STOOL ROUTINE AND MICROSCOPY

2021 ◽  
pp. 112-113
Author(s):  
Meghashree N ◽  
Rohini D ◽  
Mahendar Reddy M ◽  
A.M Koppad
Keyword(s):  
Eosinophil Count ◽  
Stool Specimen ◽  
Cross Sectional Study ◽  
Research Centre ◽  
P Value ◽  
College Hospital ◽  
Cross Sectional ◽  
Mean Values ◽  
Medical College ◽  
Absolute Eosinophil Count

Introduction: Eosinophilia is a well-known host immune response in helminthic infestation. This study was carried out to investigate whether a correlation exists between absolute eosinophil count in children with stool specimen positive for helminthic infestation. Aim And Objective: To determine average raised absolute eosinophil count in children who were having various helminthic infestation with stool specimen positive. Materials And Methods: A hospital based cross sectional study done at Navodaya medical college hospital and research centre during 2019 October to 2020 September for a period of 12 months. Both blood and stool samples were obtained from a total of 69 suspected children after examined, categorised into 2 groups. Among them 24 cases were positive of helminthic infestation and 45 cases were negative. T-test and descriptive statistics were used to analyse the data. Results: The study revealed that children infested with helminths found to have higher absolute eosinophil count (mean 4644/µl (95%CI; 3474-4212) than not infested (mean 801/µl (95%CI; 616-945) with p value <0.001. In this helminth's family; nematodes, trematodes, cestodes showed mean values of absolute eosinophil count were 5206/µl (4806-7151/µl), 4930/µl (4500-5382/µl) and 2179/µl (2500-1669/µl) respectively. Conclusions: Raised absolute eosinophil count has been observed in stool specimen positive cases of helminths, especially more in nematodes. Therefore, should be considered for a single dose of albendazole.

Hematological alteration among visceral leishmaniasis patients attending in Western Tigrai, Ethiopia, 2018/2019: A cross-sectional study

2020 ◽  
Author(s):  
Gebremedhin Gebremichail ◽  
Brhane Tesfanchal ◽  
Getachew Belay ◽  
Gebreslassie Gebremariam ◽  
Gebreyohans Teklehaymanot ◽  
...  
Keyword(s):  
Visceral Leishmaniasis ◽  
Blood Cell ◽  
Hematological Parameters ◽  
Cross Sectional Study ◽  
P Value ◽  
Sectional Study ◽  
Control Groups ◽  
Cross Sectional ◽  
Red Cell Indices ◽  
Hematological Abnormalities

Abstract Background: Hematological abnormalities are common in visceral leishmaniasis patients, which is one of the main public health problems worldwide. The most common hematological abnormalities are anemia, leucopenia and thrombocytopenia. Therefore, this study aimed to assess the hematological alteration among visceral leishmaniasis patients attending Western Tigrai, Ethiopia, 2019. Method: Hospital based comparative cross sectional study was conducted from November 2018 to March 2019 in Western Tigrai, Ethiopia. A total of 100 Visceral Leishmaniasis patients and 100 control groups were included in this study. Blood was collected and analyzed by mindray BC-5800 hematology analyzer. Data was entered and analyzed using Statistical package for social science version 23. Student independent t-test was used for data analysis. P value <0.05 was considered as statistically significant at 95% confidence level. Result: From the total 100 visceral leishmaniasis patients the following abnormalities were reported: 96(96%) anemia, 95(95%) leucopenia, 92(92%) neutropenia, 73(73%) Lymphopenia, 45(45%) eosinopenia and 97(97%) had thrombocytopenia. Red blood cell, hemoglobin, hematocrit, red cell indices and platelet were significantly lower (p<0.05) in visceral leishmaniasis patients compared with the control groups. Similarly the total White blood cell, neutrophil, lymphocyte, eosinophil and basophil count were significantly lower (p<0.05) in visceral leishmaniasis patients compared with the control groups. Conclusion: The major changes in peripheral blood of patient with visceral leishmaniasis are reduced number of red blood cells, reduction in leukocytes and decreased platelet count. Visceral leishmaniasis patients presented with anemia, leucopenia and thrombocytopenia. So this finding indicates that visceral leishmaniasis causes alterations of hematological parameters. Key words: Amastigote, Anemia, Hematological Parameters, Promastigote, Visceral leishmaniasis, Ethiopia .

scholarly journals Peak expiratory flow rate among smokers and non-smokers working in Kathmandu Medical College

2020 ◽  
Vol 10 (2) ◽  
pp. 33-35
Author(s):  
Preetu Gurung
Keyword(s):  
Cigarette Smoking ◽  
Peak Expiratory Flow ◽  
Flow Rate ◽  
Peak Expiratory Flow Rate ◽  
Cross Sectional Study ◽  
P Value ◽  
Cross Sectional ◽  
Medical College ◽  
Significant Difference ◽  
Expiratory Flow

Background: Cigarette smoking has remained a popular habit since ages. Most people are well aware of the deleterious effects of cigarette smoking yet continue to give a blind eye which dete­riorates overall public health. The purpose of the present study was to assess Peak Expiratory Flow Rate among smoking and nonsmoking staffs who work in Kathmandu Medical College. Methods: In this comparative cross-sectional study Peak Expiratory Flow Rate was obtained using Mini Wright’s Peak Flow Meter of 108 smokers and 108 nonsmokers in the age group ranging from 25-45 years. Those who never smoked or who have quit smoking for the past 2 years were grouped as nonsmokers and the smokers with history of smoking at least five or more cigarettes per day for at least two years were included in the study for measuring their Peak Expiratory Flow Rate. Data was collected, compiled and analyzed by using Statistical Package of Social Science (SPSS) software version16. Student ‘t’ test was used for group comparison. Results: The Peak Expiratory Flow Rate value was significantly reduced in the smokers (p value< 0.05). Mean Peak Expiratory Flow Rate was reduced with increasing age of the smokers. However, no significant difference was observed in Peak Expiratory Flow Rate with increase in the number of cigarettes smoked (p value> 0.05). Conclusions: In the study Peak Expiratory Flow Rate among smokers (367.13 ± 74.182) was lower than nonsmokers (471.39±60.842), which was statistically significant proving that cigarette smok­ing reduced peak expiratory flow rate.

scholarly journals Study of Patients with First unprovoked Seizure in the Eastern Part of Nepal

2019 ◽  
Vol 8 (1) ◽  
pp. 22-26
Author(s):  
Dilli Ram Kafle ◽  
Surendra Sah ◽  
Miluna Bhusal
Keyword(s):  
Recurrence Risk ◽  
Cross Sectional Study ◽  
P Value ◽  
Seizure Recurrence ◽  
Unprovoked Seizure ◽  
Cross Sectional ◽  
Medical College ◽  
Increased Risk ◽  
Neuro Imaging

Background: About 5-10% of the population get at least one seizure in their lifetime. Treatment is started in patients with first unprovoked seizure if the risk of seizure recurrence is predicted to be high. If patients with first seizure are not treated 40-50% of patients develop recurrence within 2 years of the initial seizure. Starting treatment may cause reduction in the risk of recurrence by almost one half. The aim of the study was to identify the factors causing recurrence in patients with first unprovoked seizure. Materials and Methods: It is a prospective cross-sectional study conducted at Nobel Medical College from March 2015 to March 2019. Patients who presented to Nobel Medical College with first unprovoked seizure were enrolled in the study with follow up during the hospital visit. Results: Eighty six patients participated in our study. Recurrence of seizure occurred in 21(24.4%) patients within the study period of 4 years. Abnormal Electroencephalography was significantly associated with recurrence of seizure in patients with first seizure. (P value<0.001) Neuro imaging abnormality was also associated with increased risk of seizure recurrence (Pvalue<0.001) .Starting an antiepileptic after first seizure reduced the risk of further seizure. Conclusion: Recurrence of seizure was observed in almost a quarter of patients within the study period of four years. Recurrence risk was higher in those patients with abnormal Electro encephalography and in those patients with identified cause than those patients whose seizure was assumed to be idiopathic.

scholarly journals Association between Acne and Body Mass Index: A Hospital Based Cross Sectional Study

2018 ◽  
Vol 16 (1) ◽  
pp. 53-56
Author(s):  
Saraswoti Neupane ◽  
Binamra Basnet ◽  
Tara Devi Sharma
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Acne Vulgaris ◽  
Cross Sectional Study ◽  
Normal Weight ◽  
P Value ◽  
Cross Sectional ◽  
Middle Income ◽  
Medical College ◽  
Middle Income Countries

Introduction: Acne vulgaris is a common and chronic inflammatory skin disease of pilosebaceous unit. Obesity is one of the biggest problems in western life style but nowadays, the problem is increasing even in low and middle-income countries. Body Mass Index (BMI) is used to accurately measure obesity.Objective: To find out the association between different categories of BMI and severity of acne.Materials and methods: This was a cross sectional prospective study conducted in the outpatient department of Gandaki Medical College from January to July, 2017. All the newly diagnosed patients with acne were included in the study. Height and weight of the patients was recorded and BMI was calculated. BMI was categorized as underweight, normal weight, overweight and obese. Type of lesions were noted and severity of acne was graded from 1 to 4.Statistical analysis was performed using SPSS version 17.0 for windows. One-way Analysis of Variance between groups (ANOVA) test was applied. P value of less than 0.05 was considered significant.Results: There were altogether 249 patients with acne. Age of the patients ranged from 10 to 44 years with mean age of 20.82 ±5.9 years. Most of the patients were in the age group of 11-20 years. Female: male ratio was 1:1.4. Majority of patients (65.5%) had normal BMI. Most of the patients had Grade 2 acne (52.6%). There was no significant association between the BMI and severity of acne (p=0.129).Conclusion: There was no significant association between BMI and severity of acne.

scholarly journals Interleukin 21 as a diagnostic marker of rheumatoid arthritis.

2019 ◽  
Vol 26 (08) ◽  
pp. 1229-1232
Author(s):  
Khadija Kiran ◽  
Amtul Huda ◽  
Zuhair Bhatti
Keyword(s):  
Rheumatoid Arthritis ◽  
Positive Predictive Value ◽  
Negative Predictive Value ◽  
Predictive Value ◽  
Diagnostic Marker ◽  
Cross Sectional Study ◽  
P Value ◽  
Cross Sectional ◽  
Medical College ◽  
Sensitivity Specificity

To investigate the role of IL-21 as diagnostic marker in diagnosis of rheumatoid arthritis. Study Design: Cross sectional study. Setting: Department of Physiology and Orthopedic Gujranwala Medical College, Gujranwala. Period: October 2017 to October 2018 in one year duration. Materials and Methods: A total of 150 patients were included in the study, main variables assessed in this study were positive predictive value negative predictive value, sensitivity, specificity and accuracy of IL-21 in diagnosis of rheumatoid arthritis. SPSS version 23 was used to analyze the data. P value less than or equal to 0.05 was taken as significant. Study was started after permission from hospital ethical committee and patients were informed in detail about disease and procedure to be done. Non probability consecutive sampling was used. Results: The estimated sensitivity was 93.6%. The estimated specificity was 50%. Positive predictive value was 96.3% and negative predictive value was 35.7%. The overall accuracy was 90.6% for diagnosing rheumatoid arthritis. Conclusion: IL-21 induces MMP3 in rheumatoid arthritis patients, identification of IL-21 from synovium of patients indicates the presence of rheumatoid arthritis. We observed 90.6% diagnostic accuracy of IL-21 for rheumatoid patients taking RA factor as gold standard of diagnostic tool.

scholarly journals Role of Physiotherapy in Hospitalised Patients of COVID-19 disease

2021 ◽  
Vol 9 (3) ◽  
pp. 154-159
Author(s):  
Dr. Sanjay Kumar Bharty ◽  
◽  
Dr. Jitendra Kishore Bhargava ◽  
Dr. Brahma Prakash ◽  
Dr. Vikas Patel ◽  
...  
Keyword(s):  
Severity Index ◽  
Cross Sectional Study ◽  
P Value ◽  
Cross Sectional ◽  
Medical College ◽  
Breathing Exercises ◽  
Hospitalised Patients ◽  
Before And After ◽  
Respiratory Physiotherapy

Introduction: Respiratory physiotherapy is one of the therapeutic methods in various respiratoryviral infections. Breathing exercises with other interventions, could enhance the total lung capacityand symptom alleviation in patients with virus-related acute respiratory distress syndrome (ARDS).Aim: To study the clinical evaluation of the role of physiotherapy in hospitalised patients of covid-19diseases. Method: This was an Observational (prospective, cross-sectional) study. 187 patientswere recruited and diagnosed as COVID-19 as per RTPCR at NSCB Medical College, Jabalpur (MP).Patients were randomised into the physiotherapy group and controlled group. Patients in thephysiotherapy group were undergone positional changes, prone ventilation, Breathing exercise,Resistive training, Passive joint motion, Muscle stretching, Bedside standing training, enduranceexercise by a specialized physiotherapist. Mean cough severity index, MMRC grade, respiration rateand peripheral blood saturation were recorded before and after intervention and compared with thecontrolled group. Result: There was significant improvement found in MMRC grade and respirationrate after physical therapy in the physiotherapy group (p-value < 0.05). Exertional dyspnoea andcough severity index significant deceased in physiotherapy group. The positive change was found inperipheral blood saturation. There was decreased in hospitalization stay in the physiotherapy groupas compared to the controlled group. Conclusion: Our study revealed the positive effect ofphysiotherapy on covid-19 disease in terms of symptoms and hospitalization duration among thephysiotherapy group. Physiotherapy exerts a beneficial role in the management of the covid-19disease.

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