scholarly journals Diabetes mellitus quality care management: The promise of herbal supplementation

2021 ◽  
Vol 9 (1) ◽  
pp. 007-012
Author(s):  
Arar K ◽  
Ghouini A

Overcoming diabetes is a major health challenge of the 21st century. WHO predicts that by 2030 it will be the seventh leading cause of death in the world and calls for global action to stop its rise and improve care. Actually, Herbal and nutritional supplementation is required in the management of diabetic patients, a finding shared unanimously by scientists. Recently diabetologists have come to the evidence that a therapeutic supplement consisting of nutrients and herbal is necessary to optimize the treatment of diabetes. The treatment of Type 2 diabetes mellitus, which is very often associated with overweight, is based on hygiene and dietetic measures and, where appropriate, on taking oral antidiabetics .This review describes the therapeutic arsenal of conventional oral antidiabetic drugs and emphasizes on innovative therapeutic option introducing herbal medicine and nutrition to the management of diabetic patients. Recent studies showed interesting potential in the reduction of blood sugar for many herbal for example Cinnamon, also berberine has been linked to the reduction of blood glucose levels, insulin levels and showed to be as effective as metformin, the most commonly prescribed drug for diabetics, at controlling blood sugar levels in diabetics. Moreover, a medicinal plant or herbal mixture can provide multi-targeted therapeutic action due to its complex chemical composition with hundreds of active ingredients such as oligosaccharides, alkaloids, polyphenols, flavonoids, tannins and at the same time ensure safety for the patients. We conclude by the fact that herbal and nutritional supplementation can bring major and promising progress in order to improve the patient care, by slowing the progression of type 2 diabetes and limiting its complications.

2019 ◽  
Vol 2 (4) ◽  
Author(s):  
Agung B S Satyarsa

Diabetes mellitus is a degenerative disease that commonly found and related to an unhealthy lifestyle and genetic factors. Current management of diabetes mellitus includes control of blood sugar levels and prevention of complications. Recent studies found that many phytochemicals have the potential to control blood sugar levels in patients with diabetes. Alkaloid substances from leaves of Tapak Dara have an effect on decreasing blood glucose. This review article aims to describe the potential effects of the Alkaloid vindolicine from Tapak Dara leaves (Catharanthus Roseus L.) in reducing blood glucose levels in patients with type 2 diabetes mellitus. The activity of vindolicine alkaloid against ? cells in previous studies has shown to improve ? cells activity and induce insulin secretion thus preventing further hyperglycemia. In addition, the vindolicine alkaloid also has a role in activating pancreatic ?-TC6 cells and carrying out an immediate reaction in blood vessels. As conclusion, further research is needed to prove the maximum effect of the utilization of tread leaf extract as well as the toxicity test to determine the toxic effects of the alkaloid substances in the tread leaf. Keywords: Type 2 Diabetes Mellitus, Vindolicine Alkaloid, Tapak Dara, blood glucoselevels


2019 ◽  
Author(s):  
Ernawati . ◽  
Agus Sustiyono ◽  
Mulyati .

Background: DM (Diabetes Mellitus) is a chronic/chronic metabolic disorder characterized by an increase in blood glucose levels (hyperglycemia) caused by insufficient amounts of insulin or insufficient amounts of insulin, sometimes even more effective, this condition is called insulin resistence. Objective: This study aims to determine the effectiveness of ma’tsurat dhikr therapy in reducing blood sugar levels in type 2 diabetes mellitus patients at dr. Dradjat Prawiranegara Hospital Serang in 2018. Methods: The number of samples of this study was 34 respondents and the method was quasi-experimental. The data was analyzed by independent T-Test. The respondents of experimental group received DM exercise and morning-evening dhikr intervention, while the control group only received DM exercise intervention. Results:The results of the study showed that ma’tsurat dhikr affects significantly on the decrease of bloods ugarlevelsinpatienntswithtype2DMatdr.DradjatPrawiranegara Hospital Serang with p value<0.005. Conclusion: Intervention of ma’tsurat dhikr can be recommended for type 2 DM patients with elevated blood sugar levels in patients.


Author(s):  
ALLU HARSHAVARDHINI ◽  
BHANUKUMAR MUTHAIAH ◽  
TIRIN BABU ◽  
GEORGE MATHEW PANACHIYIL ◽  
SISIRA SANTHOSH ◽  
...  

Background: Depression incidence is higher in diabetic patients when compared to the non-diabetic individuals and there exist a two-directional relationship between depression and the development of type 2 diabetes mellitus. Objectives: This study aimed to estimate the frequency of depression and the effect of antidepressant on glycemic control in type 2 diabetes mellitus patients. Methods: This prospective interventional study was conducted in type 2 diabetes mellitus patients with a sample size of 100. These patients were diagnosed with depression using WHO-ICD10 criteria. All study patients had uncontrolled blood glucose levels and were on an optimized maximal dose of combination oral hypoglycemic agents with stable glycoregulation (HbA1c 8.4 ±0.5) were taken up for the intervention with antidepressant. These patients were started on with antidepressant after enrollment and followed up for fasting blood sugar (FBS), post-prandial blood sugar (PPBS), and HbA1c at the end of 3 months and 6 months. And also Hamilton depression rating scale scores were estimated at the beginning of the study and at the end of 6 months. Results: The frequency of depression among the type 2 diabetes mellitus patients was found to be 42%. There were reduction of mean FBS levels from baseline value of 177 mg/dl to follow-up value of 160 mg/dl (p<0.001), mean PPBS levels from 251.16 mg/dl to 217.84 mg/dl (p<0.001), and mean HbA1c dropped from 8.41 to 7.57 (p<0.001) after the treatment with antidepressant. Conclusion: Our study concluded that patient started on antidepressant showed a reduction in the blood sugar levels and HbA1c levels from their baseline values, which was clinically and statistically significant.


Author(s):  
Shah Namrata Vinubhai ◽  
Pardeep Agarwal ◽  
Bushra Fiza ◽  
Ramkishan Jat

Background: Serum ferritin is known as an index for body iron stores also as an inflammatory marker and it is influenced by several disease. We were looking for a correlation between HbA1c and S. Ferritin in type 2 DM. Methodology: The present study a total of 150 participants were enrolled of which 100 were confirmed cases of Type 2 Diabetes Mellitus and rest 50 age and sex matched healthy subjects constituted the control group. All were screened for HbA1c, Fasting blood sugar, Post prandial blood sugar and S.Ferritin. Results: A highly significant variation and positive correlation was observed with respect to S.Ferritin and HbA1c levels. Mean S.Ferritin was high in the subgroup with poor glycemic control. Conclusion: The fasting, post prandial sugar levels, HbA1c and S.Ferritin were significantly higher in the diabetic subjects. This study shows a positive correlation between HbA1c and S. Ferritin levels. So we can conclude that in diabetic patients S. Ferritin may serve as an independent marker of poor glycemic and metabolic control. Keywords: Serum ferritin, Type 2 Diabetes Mellitus, HbA1c.


2019 ◽  
Vol 6 (3) ◽  
pp. 786
Author(s):  
Eda Dayakar ◽  
C. Sathya Sree ◽  
E. Sanjay

Background: Diabetes mellitus is a common health problem globally. Dyslipidaemia is a major risk factor to develop cardiovascular disease in diabetics. They present study was undertaken to find out the prevalence of dyslipidaemia in type 2 diabetic patients.Methods: The present study was a cross sectional study consisting of 46 (23 male and 23 female) known type 2 diabetes mellitus patients. Age, gender, duration of diabetes, body mass index (BMI) was recorder in all the diabetic patients.  Fasting blood glucose levels, total cholesterol, triglycerides, HDL, LDL, VLDL levels were measured using standard methods and recorded.Results: The average total cholesterol, triglycerides, LDL, HDL and VLDL were 200±42mg/dl, 169.62±89.79mg/dl, 132.45±36.38mg/dl,39.1±16.6mg/dl and 35.85±17.09mg/dl respectively. The incidence of occurrence of hypercholesterolemia was 58.6% and hypertriglyceridemia 36.9%. Increased levels of LDL were observed in 30 (65.2%) patients and reduced HDL was observed in 43 (93.4%) patients. The incidence rate of dyslipidaemia was higher in female diabetic patients when compared to male diabetic patients.Conclusions: Awareness on the dyslipidaemia and its risk factors should be provided to the type 2 diabetic patients as they are more prone to get cardiovascular disease and lipid profile also should be monitored regularly along with blood glucose levels.


Author(s):  
Nur Rasdianah ◽  
Suwaldi Martodiharjo ◽  
Tri Murti Andayani ◽  
Lukman Hakim

The increasing prevalence of diabetes mellitus (DM) in Indonesia requires participation of all parties including pharmacists. This study aims to determine the impact of the implementation of home pharmacy service guidelines for patients with type 2 diabetes mellitus on the level of knowledge, medication adherence, therapeurical satisfaction and glycemic control. This study used a quasi-experimental design with one group pre-test and post-test design involving 37 patients with type 2 diabetes mellitus who met the requirements of inclusion and exclusion criterias. The Diabetes Knowledge Questionnaire (DKQ-24) and the Diabetes Medication Satisfaction Tool (DMSAT) were used for collecting the data. Patient adherence was measured using a pillcount method and fasting blood sugar levels (FSB) data were obtained from the laboratory results. The study was conducted in two community health centers and patient’s home in the Yogyakarta Municipality area. The data were analysed using Wilcoxon and Spearman test. The results showed the change of the level of knowledge, medication adherence, therapeutic satisfaction and glycemic control before and after intervention of pharmacy services at home. The average decreasing of fasting blood sugar levels 17.09 mg/dL ± 1.43


2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Akbar Riyanto ◽  
Fajar Susanti ◽  
Erlin Ifadah ◽  
Sugeng Hadisaputra

AbstractIncreasing prevalence of type 2 Diabetes Mellitus in developed and developing countries is a health problem. Therefore, type 2 Diabetes Mellitus can be prevented by regular exercise, healthy and regular life. The purpose of this study was to determine the effectiveness of foot exercise on changes in blood sugar levels in elderly people with type 2 diabetes mellitus at the Ciracas District Health Center. This type of research is experimental with one group pre-post test design. The population in this study were 36 elderly people with type 2 Diabetes Mellitus in the Ciracas District Health Center. The sample in this study were 18 elderly with type 2 diabetes mellitus in Ciracas District Health Center. The sampling technique used was convenience sampling. Methods of data collection using an observation sheet before and after being given foot exercises. The statistical test used in this study is the paired T test. The results showed that there was no change in blood sugar levels before and after doing foot exercises, the statistical test results obtained a p value of 0.870, which means 0.870> 0.05, it can be concluded that there is no significant effect between foot exercise and changes in blood sugar levels in elderly patients. Type II diabetes mellitus at the Ciracas Subdistrict Health Center. The absence of any effect of foot exercises on changes in blood sugar levels in the elderly could be due to incomplete exercise, therefore foot exercise training to change blood sugar levels must be done in the elderly. Keywords : Foot exercise, Blood Sugar Levels, DM type 2


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