Assessment of vaginal health before and after treatment with vaginal suppository containing Lactiplantibacillus pentosus KCA1

Bacterial Vaginosis (BV) is a polymicrobial syndrome characterized by a shift in the vaginal flora from a predominant population of Lactobacilli to a replacement with anaerobes. Vaginal suppositories containing L. pentosus KCA1 were formulated using glycerol-gelatin base. A prospective and follow-up community-based study was done. Vaginal samples were collected from women of reproductive age (non-pregnant) between 18-45 years. A total of 360 women both symptomatic and asymptomatic provided High Vaginal Swabs (HVS) for BV screening using Nugent scoring method and 65 (18.1 %) participants were identified as having BV by microscopy with 45 (12.5 %) of them being consistent with BV (Nugent score of 7-10) and twenty (5.56 %) being intermediate with BV (Nugent score of 4-6). A baseline and intervention questionnaire were administered to the participants. Majority (81.5 %) of the participants affirmed that they have not heard about BV. Social burden reveals that 90.8 % affirmed that they feel frustrated, having BV symptoms recur after treatment and 83.1 % admitted that BV symptoms makes them feel embarrassed, ashamed and dirty. Majority (58.8 %) claimed that the state of their reproductive health is ‘very good’ four weeks after treatment, while 88.2 % of the participants rated their reproductive health after four weeks of treatment to be ‘somewhat better than now than a year ago’. In conclusion, it was revealed that BV has impact on the social status and quality of life of the participants except on their economic status. Knowledge on the awareness of BV among women of reproductive age is essential.

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Fertility, Migration and Acculturation (FEMINA): a research protocol for studying intersectional sexual and reproductive health inequalities

Reproductive Health ◽

10.1186/s12978-019-0795-5 ◽

2019 ◽

Vol 16 (1) ◽

Author(s):

Violeta Alarcão ◽

Miodraga Stefanovska-Petkovska ◽

Ana Virgolino ◽

Osvaldo Santos ◽

Sofia Ribeiro ◽

...

Keyword(s):

Reproductive Health ◽

Sexual And Reproductive Health ◽

Service Providers ◽

Reproductive Age ◽

Cape Verdean ◽

Women Of Reproductive Age ◽

Cross Sectional ◽

Men And Women ◽

Native Women ◽

And Gender

Abstract Background The existing knowledge on the interplay between reproductive and sexual health, migration and acculturation is recent and inconsistent, particularly on the sociocultural motives and constraints regarding fertility. Therefore, sexual and reproductive health (SRH) surveys are needed to provide accurate and comparable indicators to identify and address SRH inequalities, with specific focus on under researched aspects, such as the interrelation between migration and gender. FEMINA (FErtility, MIgratioN and Acculturation) aims to investigate intersectional SRH inequalities among Cape Verdean immigrant and Portuguese native families and how they impact on fertility in Portugal. This study will use a comprehensive approach exploring simultaneously the components of SRH, namely regarding identities, perceptions and practices of both women and men among lay people and relevant experts and stakeholders. The project has three main goals: 1) to identify social determinants of SRH among Cape Verdean immigrant and Portuguese native men and women of reproductive age; 2) to gain understanding of the diversity of the sexual and reproductive experiences and expectations of Cape Verdean immigrant and Portuguese native men and women of reproductive age, considering the singularities of their migratory, social and family dynamics; and 3) to produce recommendations for policy makers, employers and service providers on how to better address the SRH needs of Portuguese-born and immigrant populations. Methods The study will address these goals using a mixed methods approach, including: a cross-sectional telephone survey with a probabilistic sample of 600 Cape Verdean immigrant and 600 Portuguese native women and men (women aged 18 to 49 and men aged 18 to 54), residents of the Greater Lisbon Area; a qualitative research through in-depth interviews with a subsample of 30 Cape Verdean immigrants and 30 Portuguese native men and women; and a Delphi technique for finding consensus on good practices in SRH for the entire population with a special emphasis on immigrants, namely extra-EU migrants. Discussion Data will be used to produce a comprehensive set of indicators to monitor SRH in Portugal, to foster a greater understanding of its specificities and challenges to policy and decision makers, and to provide targeted recommendations to promote inclusive and migrant sensitive SRH services.

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Exploring the optimal allostatic load scoring method in women of reproductive age

Journal of Advanced Nursing ◽

10.1111/jan.14014 ◽

2019 ◽

Vol 75 (11) ◽

pp. 2548-2558 ◽

Cited By ~ 5

Author(s):

Yang Li ◽

Marie‐Anne S. Rosemberg ◽

Vanessa K. Dalton ◽

Shawna J. Lee ◽

Julia S. Seng

Keyword(s):

Allostatic Load ◽

Reproductive Age ◽

Women Of Reproductive Age ◽

Scoring Method

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Prevalence of Bacterial Vaginosis and Its Association with Risk Factors among Nonpregnant Women: A Hospital Based Study

International Journal of Microbiology ◽

10.1155/2018/8349601 ◽

2018 ◽

Vol 2018 ◽

pp. 1-9 ◽

Cited By ~ 9

Author(s):

Eliza Ranjit ◽

Bijendra Raj Raghubanshi ◽

Smrity Maskey ◽

Pramila Parajuli

Keyword(s):

Risk Factors ◽

Bacterial Vaginosis ◽

College Teaching ◽

Reproductive Age ◽

Age Group ◽

Women Of Reproductive Age ◽

Coagulase Negative Staphylococci ◽

Scoring Method ◽

Medical College ◽

Reproductive Age Group

Bacterial vaginosis (BV) is an ecological imbalance of the vaginal microbiota affecting mostly women of reproductive age group. This study was carried out among 160 nonpregnant women registered at the Outpatient Department of Gynaecology/Obstetrics of KIST Medical College Teaching Hospital, Imadol, Lalitpur, Nepal, from November 2014 to May 2015. The aim of the study was to assess the association of the risk factors with BV and analyze the type of bacteria associated with BV. Nugent’s scoring method was used for diagnosis of BV in this study. The overall prevalence of BV was 24.4% among symptomatic patients. Douching was statistically related to BV(P=0.015). Also, BV was significantly associated with consistency(P=0.0001), odor(P=0.02), and amount of abnormal vaginal discharge(P=0.09). Contraceptives users on anatomical sites were found more prone to BV than those who did not use contraceptives on anatomical sites.Pseudomonasspp.,Escherichia coli, Acinetobacterspp., Proteusspp., Klebsiellaspp., Neisseria gonorrhoeae, Enterobacterspp., Citrobacterspp., Staphylococcus aureus,Coagulase-Negative Staphylococci (CoNS),andStreptococcus agalactiaewere associated with BV and out of thoseLactobacillusspp. was the predominant organism. The higher prevalence of BV among symptomatic patients indicates interventions should be applied to reduce the incidence of stillbirth, abortion, and sterility.

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Social capital and related socio-demographic variation in women of reproductive age: A population-based study

International Social Work ◽

10.1177/0020872815620260 ◽

2016 ◽

Vol 61 (2) ◽

pp. 247-259 ◽

Cited By ~ 2

Author(s):

Azam Baheiraei ◽

Fatemeh Bakouei ◽

Eesa Mohammadi ◽

Reza Majdzadeh ◽

Seyed Mostafa Hosseni

Keyword(s):

Social Capital ◽

Low Income ◽

Family Income ◽

Population Based ◽

Cross Sectional Study ◽

Reproductive Age ◽

Women Of Reproductive Age ◽

Cross Sectional ◽

The Social ◽

Low Income Families

In this population-based cross-sectional study of women of reproductive age in Tehran, Iran, the social capital integrated questionnaire and socio-demographic questionnaire were used. The highest mean scores were related to social cohesion and inclusion dimension (55.72 ± 11.94) and the lowest mean scores to groups and networks dimension (31.78 ± 19.43). Stepwise multiple linear regressions showed the significant association between dimensions of social capital and certain socio-demographic variables, particularly family income. Policy makers should help low-income families by designing effective interventions for improving the status of social capital in this group, because it is considered one of the social determinants of health.

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Women’s health in Serbia - past, present, and future

Srpski arhiv za celokupno lekarstvo ◽

10.2298/sarh211208105p ◽

2021 ◽

pp. 105-105

Author(s):

Biljana Parapid ◽

Vladimir Kanjuh ◽

Vladimir Kostic ◽

Snezana Polovina ◽

Milan Dinic ◽

...

Keyword(s):

Clinical Trials ◽

Young Adults ◽

Reproductive Health ◽

Women Of Color ◽

The Elderly ◽

Reproductive Age ◽

Women Of Reproductive Age ◽

Late 20Th Century ◽

Part Time ◽

Cardiovascular Care

Cardiovascular and reproductive health of women have been going hand in hand since the dawn of time, however, their links have been poorly studied and once the basis of their connections started to be established in late 20th century, it depended on local regional abilities and the level of progressive thinking to afford comprehensive women?s care beyond the ?bikini medicine?. Further research identified different associations rendering more conditions sex-specific and launching therefore a slow, yet initial turn around in clinical trials? concept as the majority of global cardiovascular guidelines rely on the results of research conducted on a very modest percentage of women and even less on the women of color. Currently, the concept of women?s heart centers varies depending on the local demographics? guided needs, available logistics driven by budgeting and societal support of a broad-minded thinking environment, free of bias for everyone: from young adults questioning their gender identity, via women of reproductive age both struggling to conceive or keep working part time when healthy and line of work permits it during pregnancy, up to aging and the elderly. Using ?Investigate-Educate-Advocate-Legislate? as the four pillars of advancing cardiovascular care of women, we aimed to summarize standing of women?s health in Serbia, present ongoing projects and propose actionable solutions for the future.

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Prevalence of anaemia and its epidemiological correlates among women of reproductive age group in an urban slum of Mumbai

International Journal of Community Medicine and Public Health ◽

10.18203/2394-6040.ijcmph20173333 ◽

2017 ◽

Vol 4 (8) ◽

pp. 2841 ◽

Cited By ~ 2

Author(s):

Rushali R. Lilare ◽

Durgesh Prasad Sahoo

Keyword(s):

Economic Status ◽

Age Groups ◽

Public Health Problem ◽

Urban Slum ◽

Reproductive Age ◽

P Value ◽

Major Public Health Problem ◽

Women Of Reproductive Age ◽

Cross Sectional ◽

Rich Food

Background: Anaemia is a major public health problem affecting children, adolescent, women of reproductive age groups and lactating mothers worldwide. As per NFHS-IV data, prevalence of anaemia in India is 53%. This study was done to assess the prevalence of anaemia and its epidemiological correlates among women in reproductive age groups in an urban slum of Mumbai. Methods: This community based cross-sectional study was carried out in an urban slum in Mumbai. Total 315 women in the reproductive age groups (15-49 years) were enrolled in the study. Samples were selected by stratified random sampling from various sectors. All respondents were interviewed and haemoglobin estimation was done with Sahli’s method. Data was analysed using SPSS version 20.0 and chi-square test was used to find out the association between two qualitative variables. Results: The prevalence of mild, moderate and severe anaemia was 37.1%, 9.5% and 2.9% respectively. The factors associated with anaemia were education (p value=0.0001), socio-economic status (p value=0.001), consumption of iron rich food (p value=0.0001) and interval between two successive pregnancy in years (p value=0.0001). Conclusions: The findings of the present study revealed that education, socioeconomic status, consumption of iron rich food, interval between successive pregnancies affect the overall blood haemoglobin level on a long run. Community awareness regarding education and schooling of girls will help to increase the education level of women and would indirectly help to increase the health awareness and decrease the prevalence of anaemia.

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DETEKSI DINI KANKER SERVIKS DENGAN PEMERIKSAAN SERVIKS DI KELURAHAN BULURAN KENALI KOTA JAMBI TAHUN 2017

Jurnal Abdimas Kesehatan (JAK) ◽

10.36565/jak.v1i1.20 ◽

2019 ◽

Vol 1 (1) ◽

pp. 56

Author(s):

Julaecha Julaecha ◽

Nurfitriani Nurfitriani

Keyword(s):

Cervical Cancer ◽

Early Detection Of Cancer ◽

Malignant Disease ◽

Intraepithelial Neoplasia ◽

Cervical Cancer Prevention ◽

Reproductive Age ◽

Pap Smears ◽

Women Of Reproductive Age ◽

Before And After ◽

Implementation Method

Cervical cancer is a malignant disease that occurs in the cervik. Course of the disease is preceded by the condition of pre-concerous lesions of the cerviks is the existence of dysplasi/cervical intraepithelial neoplasia (NIS). On each day is expeced to 40-45 new cases and about 20-25 people die from cervical cancer. Based on those considered very necessary to provide education on cervical cancer in women of reproductive age in the prevention of cervical cancer prevention effort.Target outcomes expected are: there is an increased knowledge an increase in knowledge between before and after extension and capable of early detection of cancer serviks increase. Implementation method to provide counseling.The results showed that there was important of mother’s interest in doing pap smears examination before and after counseling.

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Variations in modern contraceptive uptake and its correlates in South West and North East Nigeria: a comparative analysis

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20202721 ◽

2020 ◽

Vol 9 (7) ◽

pp. 2852

Author(s):

Funmilola F. Oyinlola ◽

Samson O. Bamiwuye ◽

Stephen A. Adebowale ◽

Opeyemi O. Ekundayo ◽

Benjamin B. Ilesanmi

Keyword(s):

Reproductive Health ◽

Sexual And Reproductive Health ◽

Reproductive Age ◽

Outcome Variable ◽

Modern Contraceptive ◽

Women Of Reproductive Age ◽

North East ◽

South West ◽

Living Children ◽

Contraceptive Uptake

Background: Family planning programs are implemented specifically to address the sexual and reproductive health challenges of women of childbearing age but these interventions are yet to address regional differences in modern contraceptive usage in Nigeria. Hence, this study aimed to examine correlates of modern contraceptive uptake in South West and North Eastern, Nigeria.Methods: A cross-sectional survey data for women aged 15-49 years was extracted from Nigeria demographic and health surveys 2018 (NDHS). Data analyses were based on a weighted sample of 10,907 (North East= 5406 and South West = 5501) women of reproductive age. The outcome variable was modern contraceptive use. The main explanatory variables were age, employment status, religion, Number of living children, education, and marital status. Frequency distribution, Chi-square test, and binary logistic regression were used for data analysis (α=0.05).Results: The result showed the mean age of women of reproductive age in South West and North East to be 32years and 30 years respectively. More women in South West used modern contraceptive than women in North East. About 91.5% and 75.8% of women in North East and South West respectively did not used any modern method. The result showed that, in the South West, number of living children (OR:4.06, CI: 2.794-5.921), education (OR:1.35, CI: 1.045-1.754) and wealth index (OR:1.77, CI: 1.053-2.973) increased the odds of contraceptive uptake, while maternal age (OR:0.52, CI: 0.282-0.965), religion (OR:0.25, CI: 0.184-0.347) and place of residence (OR:0.68, CI: 0.504-0.916) significantly reduced the odds of modern contraceptive uptake in North East.Conclusions: This study concludes that there are regional variations in uptake and predictors of modern contraceptives use in Nigeria. Therefore, sexual and reproductive health interventions that considers the study’s significant variables should be put in place to increase uptake.

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Obesity and reproductive health of women

Obesity and metabolism ◽

10.14341/omet201713-8 ◽

2017 ◽

Vol 14 (1) ◽

pp. 3-8 ◽

Cited By ~ 4

Author(s):

Natalya V. Gorbatenko ◽

Vitaliy F. Bezhenar ◽

Mihail B. Fishman

Keyword(s):

Reproductive Health ◽

Negative Impact ◽

Reproductive Age ◽

Women Of Reproductive Age ◽

Female Reproductive Health

Obesity has a negative impact on female reproductive health. The review presents literature data on current views on the etiology, pathogenesis of obesity and its impact on the reproductive health of women. Particular attention is paid to problems arising in women of reproductive age who are obese.

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Immunomodulatory features of modern probiotic preparations in complex treatment of women of reproductive age with chlamydial infection in the lower genital

HEALTH OF WOMAN ◽

10.15574/hw.2016.115.123 ◽

2016 ◽

pp. 123-128

Author(s):

V.A. Benyuk ◽

◽

A.I. Kurchenko ◽

О.A. Shcherba ◽

Bu Weiwei ◽

...

Keyword(s):

Chlamydial Infection ◽

Pathogenic Bacteria ◽

Reproductive Age ◽

Chlamydia Infection ◽

Control Group ◽

Complex Treatment ◽

Women Of Reproductive Age ◽

Nonspecific Resistance ◽

Vaginal Suppository ◽

Complex Therapy

The aim of the study: assessment of influence of complex treatment of chronic recurrent chlamydial cervical infection with probiotics of various forms of the use on the immune status and the vaginal microbiocenosis in women of reproductive age. Materials and methods. The study surveyed 87 women of age from 18 to 35 years, from which 67 patients of recurrent chlamydial cervicitis, which (according to the protocol) were eligible for inclusion. The control group included 20 gynecologicaly healthy women. All surveyed women were representative by age and data of the obstetric-gynecologic and somatic anamnesis. In accordance with the objectives of the study, all patients with chlamydia infection (CHI) before the appointment of therapy were randomized into two groups matched for age, symptoms and duration of the inflammatory process. The I (main) group included 35 patients who underwent complex therapy. Part of therapy included drugs Sumamed 250 mg (1 capsule) 1 time a day for 5-7 days according to the scheme: 1st day – 1 g (4 capsules) with the 2nd -3rd day – 500 mg per day (2 capsules) and 4th – 7th day – 250 mg per day (1 capsule). Topically applied combination of reparative, anti-inflammatory and antimicrobial drug Depantol in the form of suppositories – appointed standard one vaginal suppository twice a day for 10 days. Later was appointed eubiotic Lacto® 2 capsules 3 times a day during 3 weeks. The II group included 32 patients (comparison group) who underwent treatment involving Sumamed and Depantol, but with the subsequent appointment of local eubiotiks (1 vaginal suppository at night) – 10 days. Results. The results of the survey of women of reproductive age with chronic recurrent chlamydial cervicitis during colposcopic study found a high frequency of cervical pathologies, namely, inflammatory changes – 100%, ectopia prismatic epithelium – 32.8%, the true erosion – 19.4%, that in 5.9% cases was combined with leukoplakia, and dysplasia – 16.4%, which correlated with cytological examination (ASCUS – 68.6%, LSIL – 25.5%, HSIL and 2.9%). Most women with CHI noted deep violations of microbiocenosis of the vagina with a predominance of opportunistic pathogenic bacteria: Peptostreptococcus – in 43.3%, Corynebacterium – in 56.7%, epidermal staph in 65.7% and gardnerellas – in 74.6%, candida – in 46.3% of cases. Patients with CHI were stated a lack of interferon Genesis – reduction of IFN-a 1.4-fold and IFN-g – 1.8 times. Conclusion. The complex therapy of chronic recurrent chlamydial cervicitis in women of reproductive age was conducted by the developed algorithm with the inclusion of oral probiotic Lacto® contributed to the increase of parameters of nonspecific resistance of the organism in 88% of cases, which was reflected in the reduction of titers of specific IgM 1.4-fold, IgG – 1.8 times, raising the level of lysozyme in cervical mucus – 1.5 times and sIgA – 1.2 times, the restoration of cytokine profile and normalization of microbiocenosis of the vagina in 76.4% of women. Key words: probiotics, immunity, cytokines, T-lymphocytes, microbiocenosis, Saccharomyces, Bifidobacterium, antibiotic-associated diarrhea, chlamydial infection, efficiency.

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