scholarly journals Alcohol and Glucose D consumption decreases grip muscle strengths in graded doses

2021 ◽  
Vol 4 (1) ◽  
pp. 039-046
Author(s):  
Omoirri Moses Aziakpono ◽  
Uyovwiesevwa Ataihire Johnson ◽  
Orji Uchechukwu Harrison ◽  
Chukwuemeka Charles Ofili ◽  
Nwosu Gloria Chizoba ◽  
...  

Alcohol, Blood Sugar, and Grip muscle strengths (GMS) may play key role in injury prevention and rehabilitation. In many cases, strengthening of the grip has been a prescription for rehabilitation from injuries such as golf and tennis elbow. In this study, the effects of alcohol and glucose consumption on grip muscle strength in early adult male subject was investigated. A total of thirty (200) human subjects of about18+ years old were recruited for the study. The subjects were administered varying doses of alcohol and glucose D, then allowed to rest for a period of 5 and 10 minutes before assessing their grip muscle strength, fasting blood sugar (FBS) and body weights. Obtained records were then compared with those of control (normal) subject who neither received alcohol nor glucose D. Differences in mean was obtained between groups using the student t-test. From the result, study found a statistically significant decrease (p < 0.05) in GMS for different times (5 min and 10 min) of alcohol administration as compared with control subjects. A notable significant decrease (p > 0.05) was also observed for FBS with increasing administration times as compared with control. This decrease was however insignificant for 10 min duration compared with 5 minutes. This decrease was however significant (p < 0.05) for alcohol 5 min intake as compared with control group. All test group (experimental) showed a statistically significant decrease in GMS after alcohol administration as compared with control. Lastly, a statistically significant decrease (p < 0.05) was observed in GMS for 10 min of Glucose D intake. Whereas, subject who took glucose D in 5 min showed an insignificant decrease as compared with control. It is recommended that more studies be conducted to corroborate the result of this study.

1955 ◽  
Vol 18 (4) ◽  
pp. 553-554 ◽  
Author(s):  
Jørgen Pedersen

SUMMARY Birth weight and length of 122 surviving babies of diabetics, born in Rigshospitalet, Copenhagen 1926–1947, was compared to a control group of 122 infants of non-diabetics (matched controls). The groups were comparable, especially as to foetal age and parity of the mother, severe complications in the mothers, etc. The average foetal age was 261 days (range 237–301). The average weight and length for the infants of non-diab. controls was 3045 gm. and 49.5 cm., for infants of diabetics 3600 gm. and 51.0 cm. Thus on average infants of diabetics weigh 550 gm. more and are 1.5 cm. longer than are infants of non-diab. Differences of the same magnitude were found in primiparae and in multiparae with and without obesity. The frequency distribution curves for weight and length are nearly normal, but placed at higher levels than are those of non-diab. infants. Diabetics get big and small infants as others, but the whole population is bigger than that of non-diabetics' infants. There is an actual overgrowth. In a personal series from 1946–1953 75 infants of long-term treated (1. t.) were compared to 91 infants of short-term treated (sh. t.) diabetics. The foetal age was 237 days or more, on average 260 days. Average weight and length for 1. t. infants was 3380 gm. and 50.5 cm., for sh. t. 3570 gm. and 51.3 cm. Thus the 1. t. infants on average weighed 190 gm. less and were 0.8 cm. shorter than sh. t. infants. So far these differences are not statistically significant, but an inverse correlation between the length of the last consecutive stay of the mother in Department B and the infants' weight and length could be demon I. Published in extenso in Acta endocrinol. 16, 330, 1954. strated. As the length of stay increases, weight and length decreases. This indicates the differences found to be due to the length of our treatment. As there is a positive correlation between the maternal pregnancy level of blood sugar (foetal glucose supply) during the last 6–7 weeks of pregnancy and the birth weight and length of infants of non-diabetic controls, 1. t. and sh. t. diabetics, the maternal pregnancy level may play a part of its own for the differences found in weight and length of the infants in these 3 groups. The maternal blood sugar level may influence weight and length of the infants directly (foetal glucose consumption) but also indirectly (foetal insulin turn-over rising with a rising supply of glucose), as foetal insulin may act as a growth stimulating factor.


2012 ◽  
Vol 4 (3) ◽  
pp. 775-781 ◽  
Author(s):  
G. S. Gaur ◽  
A. K. Dixit

This study aims to assess the comparative effects of vitamin C supplementation on lipid profiles in male and female human subjects. A total of 60 healthy individuals (male and female) were selected randomly, instructed and given the understanding of the purpose of study. The test group comprising  30 individuals  were given 500mg vitamin C tablets one daily for 30 days and control group of 30 individuals were given placebo capsules(glucose 500mg)  one daily for 30 days. Fasting blood samples were collected in the morning for estimation of cholesterol, triglycerides, HDL-C, LDL-C and VLDL-C on first day of the commencement of the study and second blood samples were taken after thirty days of supplementation and same estimations were carried out. Vitamin C caused reduction in serum total cholesterol and LDL cholesterol significantly but it did not have any statistically significant effect on HDL-C, VLDL-C and triglycerides. As far as gender is concerned the effect of vitamin C on lipid profile in males was not significantly different from those in females.© 2012 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved.doi: http://dx.doi.org/10.3329/jsr.v4i3.8894 J. Sci. Res. 4 (3), 775-781 (2012)


Author(s):  
Vidya Pradeep Kumar ◽  
Ramya G. Rao ◽  
A. Dhali ◽  
Vandana Thammiaha ◽  
Manpal Sridhar

Background: Fungal laccases have widespread application in a number of biotechnological processes including the biodegradation of lignin. Their low yield in the native state limits their practical use in the deconstruction of lignocellulosic biomass for feeding ruminants. Enzymes in bulk quantities are required to treat biomass which has got greater product consistency and less lot to lot variations. The present study was an attempt to evaluate the effect of feeding finger millet straw treated with exogenous laccases in heifers.Methods: The effect of feeding exogenous laccases obtained from immobilized Schizophyllum commune (MTCC 11893) on body weight gain, dry matter intake and nutrient digestibility in heifers was evaluated in three groups of heifers (4-each) with body weights ranging between 275 ± 47.12 to 276.75 ± 64.48kg. The control group received ad lib. finger millet straw treated with only production media (GI). Test group 1 (GII) received ad lib. straw treated with laccase rich media in a 3:5 (w/v) ratio, while test group 2 (GIII) received ad lib. straw treated in a 4:5 (w/v) ratio. Result: After 14- days of feeding, gain in body weights for GI, GII and GIII were 277.9 ± 68.47; 277.50 ± 46.43 and 278.85 ± 37.22 respectively with an overall increase of 1.15, 4.25 and 3.60 kgs. No significant variation (P greater than 0.05) was observed with regard to DMD (%) between the groups which was 46 ± 5.8 for the control animals and 41±13.0 and 41± 3.4 in G2 and G3 groups. Though significant variations were observed digestibility studies proved inconclusive. Though preliminary results indicate that applying lignin degrading enzymes as feed supplements could enhance digestibility of crop residues in ruminants.


2003 ◽  
Vol 83 (4) ◽  
pp. 703-712 ◽  
Author(s):  
H. T. Korhonen ◽  
L. Jauhiainen ◽  
T. Rekilä

A study on the behavioural and welfare effects of in-cage sandboxes was carried out on juvenile farm-bred blue foxes (Alopex lagopus) with special reference to digging behaviours and time spent on sand substrate. Twelve juvenile male blue foxes were used in each of two experimental groups: (1) a test group and (2) a control group. Animals were raised singly in cages measuring 120 cm long × 105 cm wide × 70 cm high, from weaning in July to pelting in December. All experimental animals were housed conventionally but cages of the test group contained in-cage sandboxes (80 cm long × 40 cm wide × 14 cm high). Various physiological, behavioural, health and production related variables were measured during the study. Final body weights of test animals were significantly (P = 0.05) lower than controls. Occurrence of endoparasites (Toxascaris leonina, Isospora sp.) did not substantially differ between groups. Open field activity was greater (P = 0.02) and latency to touch novel objects shorter (P = 0.02) in the test group compared with the control. Cortisol-creatinine ratio, incidence of stereotypes, size of adrenals or other organs, blood screen and fur quality parameters were not significantly different. Sandbox hygiene deteriorated rapidly during the experimental period. Fur coats of test animals were dirtier than those of controls at pelting. Claw length of test animals was significantly shorter (front foot; P < 0.005, back foot, P < 0.001) than in controls only in October. Altogether nine different sandbox behaviours were observed in the test foxes. Digging was the fifth most common behavior, comprising 5.8% of total sandbox use. Amount of time spent in the sandbox peaked in July, averaging 117 min/24 h, and declined towards winter. The most common sandbox behaviours observed were walking (24.3% of total time), sitting (22.0%) and resting (17.5%). Results indicated low motivation to use in-cage sandboxes as a digging substrate. On the other hand, the presence of in-cage sandboxes may provide opportunities for foxes to engage in other species-specific activities and/or seek sensory comfort through contact with the sand. The effects of in-cage sandboxes on animal welfare need further study. Key words: Alopex lagopus, sand floor, digging, motivation, welfare, fur farming


Author(s):  
Pavithra D ◽  
Praveen D ◽  
Vijey Aanandhi M

Aim and Objective: The aim of the study was to evaluate the role of Vitamin E supplementation in Type II diabetes mellitus (DM), to determines whether people with Type II DM treated with hypoglycemic agents alone, with or without Vitamin E, to determines the drug interaction in such treatment regimen, and to evaluates the Safety of the regimen.Methods: Type II DM patients with or without complications were included in this study along with serum glycated hemoglobin (HbA1c) concentration between 7.5% and 9.5%. They are divided into test group (which received hypoglycemic agent along with Vitamin E 4000 IU) and control group. Body mass index (BMI) status, fasting blood sugar (FBS), and post-prandial blood sugar (PPBS) were noted once in a month, HbA1c percentage, total cholesterol level (TC), and serum Vitamin E level were estimated and noted for every 3 months at total 9 months of this study. Patients with other comorbid conditions were prominent in this study.Results: It is perceptible with the analysis of obtained data that FBS, PPBS, HbA1c percentage, TC level, and BMI status of the patients were declined gradually in test group (patients with Vitamin E supplementation along with their hypoglycemic agents). Thus, antioxidant therapy is highly propitious whereby delaying the onset of complications in patients with DM. This development would be highly helpful for diabetic patients.


2003 ◽  
Vol 83 (1) ◽  
pp. 29-36 ◽  
Author(s):  
Jane M Eason ◽  
Stephen L Dodd ◽  
Scott K Powers

Abstract Background and Purpose. Administration of glucocorticoids results in atrophy and contractile dysfunction in the rat diaphragm. Anabolic steroids may be useful in preventing atrophy and contractile dysfunction. The purpose of this study was to assess the effects of simultaneous administration of testosterone and glucocorticoids on morphological and contractile properties of the rat diaphragm. Subjects. Eighty-eight adult female Sprague-Dawley rats were divided into 1 of 4 groups: a control group that was given sham injections for 13 days (CONT group, n=23), a group that was given prednisolone injections (0.5 mg/100 g) for 10 days (PRED group, n=23), a group that was given testosterone injections (0.5 mg/100 g) for 13 days (TEST group, n=18), and a group that was given a combination of prednisolone and testosterone injections (0.5 mg/100 g) for 10 and 13 days, respectively (COMBO group, n=23). Methods. The animals were weighed daily, and drug doses were adjusted to changes in body mass. Twenty-four hours following the final injection, animals were weighed and sacrificed and the diaphragm was removed and weighed. A small strip of diaphragm was attached to a force transducer to determine normalized maximal isometric tetanic tension (PO). Results. Body weights in the PRED group were decreased by 26% as compared with body weights in the CONT group, and body weights in the COMBO group were decreased by 11% as compared with body weights in the CONT group. Diaphragm weights in the PRED and COMBO groups were decreased by 22% and 12%, respectively, as compared with diaphragm weights in the CONT group. Normalized maximal isometric tetanic tension was decreased by 11% in the PRED group as compared with PO in both the CONT and TEST groups and was decreased by 13% as compared with PO in the COMBO group. There was no difference in PO among the CONT, TEST, and COMBO groups. Discussion and Conclusion. The results support the hypothesis that simultaneous administration of testosterone with glucocorticoids would prevent a decrease in PO. The results indicate that simultaneous administration of testosterone with glucocorticoids prevented the loss in body weight and partially attenuated the loss in diaphragm weight that is commonly observed when glucocorticoids are given alone. These data support the notion that testosterone may be useful in the prevention of glucocorticoid-induced atrophy.


2018 ◽  
Vol 29 (01) ◽  
pp. 45-52
Author(s):  
Marlena Drężewska ◽  
Zofia Śliwińska ◽  
Marzena Wiernicka ◽  
Zbigniew Śliwiński ◽  
Grzegorz Śliwiński

Abstract Objectives The objective of this study was to assess the effectiveness of application of Kinesiology Taping for musculoskeletal system disorders in dancers, in comparison with the standard physiotherapy procedures. Design Cross-sectional study. Methods Examined were 77 dancers of the Dance Theater from Poland, both male and female (58 women and 19 men), 18–25 years old (M=20.03, SD=2.67), who experienced pain in musculoskeletal system and who specialized in jazz dancing. All the examined patients had undergone a three weeks long therapy. In the test group (N=52), Kinesiology Taping was applied to the selected groups of muscles, peripheral joints and spine, with the tapes being replaced 3 times, after each 7 days of therapy. In the control group (N=25), the standard physiotherapy procedures were applied. For the assessment of effectiveness of the therapies, there were used: interviews, measurement of pelvic static, measurement of muscle strength with a dynamometer, measurement of hip joint range of motion with a digital inclinometer and measurement of pain with VAS. Results Kinesiology Taping application has brought significant improvements in recovering proper pelvic static, increasing muscle strength, extending active range of motion of hip joints and lowering level of subjective sensation of pain. Conclusions Effectiveness of the Kinesiology Taping application for musculoskeletal system disorders in dancers is comparable with the standard physiotherapy procedures, which makes it possible to obtain a similar therapeutic effect, using the painless, well accepted by patients method of treatment, which is addition costs less.


2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Donatus Onukwufor Onwuli ◽  
Holy Brown ◽  
Harrison Anaezichukwuolu Ozoani

The antihyperglycaemic activity of Tetracarpidium conophorum nut (walnut) was investigated in albino rats. A total of 20 albino rats were used for the study. The rats were divided into five groups (A–E) of four rats each. Diabetes were induced in the rats except four which served as the positive control group A. Groups B (negative control), C, D, and E contain diabetic rats each with blood sugar level ≥17.00 mmol/L. Groups A and B were fed on 85.2 g of top feed grower over the test period. Test groups C, D, and E were fed on 21.3 g, 42.6 g, and 85.2 g of walnuts, respectively, and their fasting blood sugar (FBS) levels were checked on daily basis. Fasting blood glucose levels of the test groups were significantly lower than negative control P<0.05, for 3rd, 7th, and 10th days of the test. There were also significant increase in the body weight and hemoglobin concentration and a decreased urine output of the test group compared with the controls. These results indicate that Tetracarpidium conophorum nut (walnut) has an antihyperglycemic effect in diabetic rats.


2020 ◽  
Vol 5 (2) ◽  
pp. 288-297
Author(s):  
Eka Kumalasari ◽  
◽  
Syifa Maharani ◽  
Aditya Maulana Perdana Putra ◽  

Diabetes Mellitus (DM) is a collection of metabolic symptoms that arise in a person caused by an increase in blood glucose due to damage to insulin secretion or resistance to insulin or both. Diabetes mellitus medication can be either parenteral or oral which can cause side effects in long-term use such as mild diarrhea, bloating, fatigue acidosis, even hypoglycemic renal impairment. To prevent it can use alternative medicine using Dayak onion (Eleutherine palmifolia (L) Merr.). One of the active substances contained in the Dayak onion is the flavonoids. Flavonoids have antidiabetic activity through their functions as antioxidants. The study aims to determine the activity of Dayak scallion Extract (Eleutherine palmifolia (L) Merr.) To decrease blood sugar levels (Mus muscullus), which is glucose-induced. The research was conducted with research draft pre and post test with control group design. The mice used amounted to 25 male white mice that were divided into 5 groups i.e. negative control (CMC Na 0.5%), control positive (Glibenklamid 3 mg/kgBB), Dayak onion-leaf ethanol extract at a dose of 50 mg/kgBB, 100 mg/kgBB and 200 mg/kgBB. Observations of the decrease in blood sugar levels of each test group were conducted on the same day, 30 minutes, 60 and 90 after hyperglycemia. Results showed that Dayak onion leaves ethanol extract had activity as a lowering of blood sugar levels in glucose-induced white mice


2014 ◽  
Vol 84 (1-2) ◽  
pp. 5-11 ◽  
Author(s):  
Eun Y. Jung ◽  
Sung C. Jun ◽  
Un J. Chang ◽  
Hyung J. Suh

Previously, we have found that the addition of L-ascorbic acid to chitosan enhanced the reduction in body weight gain in guinea pigs fed a high-fat diet. We hypothesized that the addition of L-ascorbic acid to chitosan would accelerate the reduction of body weight in humans, similar to the animal model. Overweight subjects administered chitosan with or without L-ascorbic acid for 8 weeks, were assigned to three groups: Control group (N = 26, placebo, vehicle only), Chito group (N = 27, 3 g/day chitosan), and Chito-vita group (N = 27, 3 g/day chitosan plus 2 g/day L-ascorbic acid). The body weights and body mass index (BMI) of the Chito and Chito-vita groups decreased significantly (p < 0.05) compared to the Control group. The BMI of the Chito-vita group decreased significantly compared to the Chito group (Chito: -1.0 kg/m2 vs. Chito-vita: -1.6 kg/m2, p < 0.05). The results showed that the chitosan enhanced reduction of body weight and BMI was accentuated by the addition of L-ascorbic acid. The fat mass, percentage body fat, body circumference, and skinfold thickness in the Chito and Chito-vita groups decreased more than the Control group; however, these parameters were not significantly different between the three groups. Chitosan combined with L-ascorbic acid may be useful for controlling body weight.


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