scholarly journals The Potency of Candida albicans Protein Extract as Bioresptor on Immunocencor to Diagnose Candidiasis

2017 ◽  
Vol 3 (2) ◽  
pp. 26
Author(s):  
Masfufatun Masfufatun ◽  
Akhmad Sudibya ◽  
Nur Kumala
Keyword(s):  
Candida Albicans ◽  
Blood Culture ◽  
Protein Content ◽  
Specific Activity ◽  
Research Result ◽  
Positive Control ◽  
Negative Control ◽  
Protein Extract ◽  
Control Serum ◽  
Snail Enzyme

So far, diagnosing on candidiasis has still been limited in standard blood culture. The traditional method of this microbiology culture is less sensitive, many patients with candidasis infection have negative blood culture, and need a long time. This case encourage many researchers to use another alternative methode to diagnose. The purpose of this research is to examine the potency of Candida albicans protein extract as bioreseptor on immunocencor to  detect  Candida albicans and its biofilm in the blood of candidiasis patients. The research method which is used is descriptive with the following steps : (1) isolating enzim from the liquid of digestive gland of snail (Achatina fulica); (2) extraction of protein candida albicans  through  enzimatis and mechanic methods and (3) Analyzing the protein extract as bioreseptor through immunodot assay.The research result shows that the snail enzyme has the protein content 1.35 mg/ml and the specific activity 1.96 unit/mg. This snail enzyme can hydrolyze  the cell wall of Candidia albicans  and, with the help oh sonication, produce extract of planktonic extracel protein (PEP) and biofilm (PEB), extract of planktonic intracell protein (PIP), and biofilm (PIB), with each protein content 1.44; 1.29; 1.29 and 1.21 mg/ml. The characeristic of biofilm intracell protein (PIB) is antigenic on antibody anti-candida (positive control) with giving red spot on immunodot assay. Immunodot assay can distinguish negative control serum (health man) and positive Candidiasis control by using antigen 1 ng/nl and 50nl serum.

Aktivitas Antifungi Air Perasan Bawang Merah (Allium ascalonicum L.) Terhadap Candida albicans Secara In Vitro

2017 ◽  
Vol 9 (2) ◽  
pp. 71
Author(s):  
Nurhasanah Nurhasanah ◽  
Fauzia Andrini ◽  
Yulis Hamidy
Keyword(s):  
Candida Albicans ◽  
Antifungal Activity ◽  
Allium Sativum ◽  
Fungicidal Activity ◽  
Positive Control ◽  
Negative Control ◽  
Randomized Design ◽  
Significant Difference ◽  
Completely Randomized Design

Shallot (Allium ascalonicum L.) has been known as traditional medicine. Shallot which has same genus with garlic(Allium sativum L.) contains allicin that is also found in garlic and has been suspected has fungicidal activity toCandida albicans. It is supported by several researches. Therefore, shallot is suspected has antifungal activity too.The aim of this research was to know antifungal activity of shallot’s water extortion againsts Candida albicans invitro. This was a laboratory experimental research which used completely randomized design, with diffusion method.Shallot’s water extortion was devided into three concentrations, there were 50%, 100% and 200%. Ketoconazole 2%was positive control and aquadest was negative control. The result of this research based on analysis of varians(Anova), there was significant difference between several treatments and was confirmed with Duncan New MultipleRange Test (DNMRT) p<0,05, there was significant difference between 100% shallot’s water extortion with othertreatments, but there was no significant difference between 50% shallot’s water extortion with 200% shallot’s. Theconclusion was shallot’s water extortion had antifungal activity againsts Candida albicans with the best concentration100%, but it was lower than ketoconazole 2%.

scholarly journals Hypoglycaemic Property of Nutraceuticals

1970 ◽  
Vol 6 (2) ◽  
pp. 105-107
Author(s):  
Mohammad Emdadul Haque ◽  
Quazi Safayetullah ◽  
Monira Ahsan ◽  
Sheikh Nazrul Islam
Keyword(s):  
Glucose Level ◽  
Day Treatment ◽  
Positive Control ◽  
Serum Glucose ◽  
Negative Control ◽  
Diabetic Rats ◽  
Serum Glucose Level ◽  
Diabetic Rat ◽  
Black Cumin ◽  
Control Serum

Hypoglycemic property of four nutraceuticals named - black cumin, garlic, methi and karela has been investigated on an alloxan induced diabetic rat model. Glibenclamide was used as positive control and normal saline was used as negative control. Serum glucose levels of normal and diabetic induced rats were estimated by Glucose Oxidase method using a kit, and it were 4.33 ± 0.43 mmol/L and 8.27 ± 0.45mmol/L respectively. The alloxan induced diabetic rats were grouped into six, which were then treated with the four nutraceuticals and two controls. Treatment was given orally everyday for 28 days. Serum glucose level was analysed every 7 day intervals. It was observed that lowering of glucose level was significant (P = 0.01) for every 7 day treatment period. All of the nutraceuticals reduced the serum glucose level nearly to the normal value within 28 days. The rate of lowering of the glucose level was found to vary with the nutraceuticals. Garlic was found to be most active like the glibenclamide. The next active one was black cumin followed by methi and karela. The study conclude that nutraceuticals possess significant hypoglycemic property. Key words: Hypoglycaemia; Nutraceuticals; Black cumin; Garlic; Methi; Karela. Dhaka Univ. J. Pharm. Sci. 6(2): 105-107, 2007 (December)

EFEKTIVITAS SUPLEMENTASI TERIPANG EMAS (Stichopus hermanii) DALAM MENCEGAH TERJADINYA ORAL CANDIDIASIS PADA TIKUS WISTAR

DENTA ◽  
2018 ◽  
Vol 12 (1) ◽  
pp. 9
Author(s):  
Endah Wahjuningsih ◽  
Paramita Devi Oktaviani ◽  
Dwi Andriani
Keyword(s):  
Candida Albicans ◽  
Oral Candidiasis ◽  
Positive Control ◽  
Negative Control ◽  
Male Rats ◽  
Significant Difference ◽  
Post Test ◽  
Mail Address ◽  
E Mail ◽  
Tongue Epithelium

<p><strong><em>ABSTRACT</em></strong></p><p><em> </em></p><p><strong><em>Background:</em></strong><em> </em><em>Candida albicans is normal flora of oral cavity that can be pathogenic due to predisposition influence so that trigger Oral candidiasis. Stichopus hermanii suspected as an Oral candidiasis therapy because it contain antioxidant compound, antitumor and antifungi. <strong>Objective:</strong> Analyzing the effectiveness of Stichopus hermanii supplementation as a </em><em>protective effect</em><em> of oral </em><em>candidiasis in Rats exposure to smoke. <strong>Materials and Methods:</strong> This experiment is post test only group control design using 35 male rats divided into 5 groups(X). X1 (negative control), X2 (positive control), X3 (Stichopus hermanii powder 0,0225mg/kgBB), X4 (Stichopus hermanii powder 0,045mg/kgBB), X5 (Stichopus hermanii powder 0,09mg/kgBB). Candida albicans induced into the mouth by an oral swab using cotton bud 3 times a week for 8 weeks. Smoke exposure as a predisposition factor be given 3 bars per day for 8 weeks. The rats being killed and tongue biopsies measure the thickness of tongue epithelium. The obtained data analyzation using One Way ANOVA and LSD test. <strong>Result: </strong>There is a significant difference (p&lt;0.05) between X1 and X2, X1 and X3, X1 and X4, X1 and X5, X2 and X3, X2 and X4, X2 and X5, X3 and X5</em>.<em> <strong>Conclusion:</strong> Adduction of Stichopus hermanii capable of reducing risk of Oral candidiasis. Supplementation of Stichopus hermanii powder 0,09mg/kgBB is the most effective reduce thickness of the tongue epithelium in the group that exposure to smoke and induced of Candida albicans.</em></p><p><strong><em>Keywords:</em></strong><em> Stichopus hermanii, Oral candidiasis, Tongue, Candida albicans, Thickness of Epithelium</em><em> </em></p><p><em><strong>Correspondence</strong>: Endah Wahjuningsih, Laboratorium Biologi Oral Fakultas Kedokteran Gigi Universitas Hang Tuah, Jl, Arif Rahman Hakim 150, Surabaya, Indonesia. Ph 031-5945864, fax: 031-5912191, e-mail address: [email protected]</em></p>

scholarly journals Efektivitas perasan daun seledri (Apium graveolens Linn.) sebagai pembersih gigi tiruan terhadap pertumbuhan Candida albicans pada basis gigi tiruan nilon termoplastikThe effectiveness of celery leaf juice (Apium graveolens Linn.) as a denture cleaner against the growth of Candida albicans on thermoplastic nylon denture base

2020 ◽  
Vol 32 (3) ◽  
pp. 184
Author(s):  
Dhilan Purna Aji ◽  
Achmad Gunadi ◽  
Tantin Ermawati
Keyword(s):  
Candida Albicans ◽  
Positive Control ◽  
Negative Control ◽  
Apium Graveolens ◽  
Control Group ◽  
Control Group Design ◽  
Denture Base ◽  
Significant Difference ◽  
Post Test ◽  
Leaf Juice

Pendahuluan: Basis gigi tiruan nilon termoplastik merupakan alternatif pengganti basis gigi tiruan resin akrilik. Pembersihan gigi tiruan diperlukan untuk menjaga basis gigi tiruan agar tetap bersih dari kontaminasi mikroorganisme. Daun seledri merupakan bahan alam yang memiliki kandungan flavonoid, saponin, tanin, dan minyak atsiri yang sudah terbukti bersifat antijamur. Penelitian sebelumnya hanya melihat zona hambat saja. Tujuan penelitian adalah menganalisis efektivitas perasan daun seledri sebagai pembersih gigi tiruan terhadap pertumbuhan Candida albicans pada basis gigi tiruan nilon termoplastik. Metode: Eksperimental laboratoris dengan rancangan penelitian post-test only control group design. Sampel nilon termoplastik berbentuk cakram dengan diameter 10 mm dan tebal 2 mm  sebanyak 25 dibagi menjadi 5 kelompok. Sampel dikontaminasi dengan C. albicans setelah direndam dalam kontrol negatif (akuades) selama 6 jam, kontrol positif (tablet effervescent) selama 15 menit, dan perasan daun seledri konsentrasi 25, 50, dan 100% selama 6 jam. Sampel selanjutnya diletakkan dalam media sabouraud dextrose broth (SDB). Pengujian efektivitas perasan daun seledri dilakukan dengan menentukan nilai absorbansi kekeruhan media SDB menggunakan spektrofotometer. Data dianalisis menggunakan one-way ANOVA dan Least Significant Difference (LSD). Hasil: Nilai konsentrasi C. albicans pada kelompok kontrol negatif mendapatkan hasil 0,380 x 108 CFU/mL, kontrol positif mendapatkan hasil 0,310 x 108 CFU/mL, perasan daun seledri konsentrasi 25% mendapatkan hasil 0,243 x 108 CFU/mL, konsentrasi 50% mendapatkan hasil 0,160 x 108 CFU/mL, dan konsentrasi 100% mendapatkan hasil 0,236 x 108 CFU/mL. Simpulan: Perasan daun seledri efektif sebagai pembersih gigi tiruan untuk menghambat  pertumbuhan C. albicans, dengan konsentrasi yang efektif sebesar 50%.Kata kunci: Nilon termoplastik, perasan daun seledri, Candida albicans. ABSTRACTIntroduction: Thermoplastic nylon denture base is an alternative to the acrylic resin denture base. Denture cleaning is needed to keep the denture base clean from contamination by microorganisms. Celery leaves are natural ingredients that contain flavonoids, saponins, tannins, and essential oils that have been proven to have antifungal properties. Previous research only observed the inhibitory zone. This research was aimed to analyse the effectiveness of celery leaf juice as a denture cleaner against the growth of Candida albicans on thermoplastic nylon denture base. Methods: Experimental laboratory with a post-test only control group design was conducted towards 25 disc-shaped thermoplastic nylon samples with a diameter of 10 mm and a thickness of 2 mm, and divided into five groups. Samples were contaminated with C. albicans after immersion in the negative control (aquadest) for 6 hours, positive control (effervescent tablets) for 15 minutes, and celery leaf juice with the concentrations of 25, 50, and 100% for 6 hours. The sample was then placed in the Sabouraud-dextrose broth (SDB) medium. The effectiveness of celery leaf juice was tested by determining the absorbance value of SDB media turbidity using a spectrophotometer. Data were analysed using one-way ANOVA and Least Significant Difference (LSD). Results: The concentration value of C. albicans in the negative control group was 0.380 x 108 CFU / mL, the positive control was 0.310 x 108 CFU / mL, the juice of celery leaves with the concentration of 25% was 0.243 x 108 CFU / mL, the concentration of 50% was 0.160 x 108 CFU / mL, and the concentration of 100% was 0.236 x 108 CFU / mL. Conclusion: Celery leaf juice is effective as a denture cleaner to inhibit the growth of C. albicans, with an effective concentration of 50%.Keywords: Thermoplastic nylon, celery leaf juice, Candida albicans.

scholarly journals Physicochemical and sensory properties of traditional baked cake (kuih baker) with coconut milk and soy milk

Food Research ◽  
2020 ◽  
Vol 4 (5) ◽  
pp. 1435-1443
Author(s):  
Maimanah-Faizah I. ◽  
Ismail-Fitry M.R. ◽  
Umi Hartina M.R. ◽  
Rozzamri A.
Keyword(s):  
Protein Content ◽  
Sensory Evaluation ◽  
Positive Control ◽  
Proximate Analysis ◽  
Negative Control ◽  
Sensory Properties ◽  
Coconut Milk ◽  
Colour Properties ◽  
Soy Milk ◽  
Significant Difference

Coconut milk is widely used in Malaysia as one of the essential ingredients in preparing traditional baked cake or ‘kuih bakar’. Increased demand for coconut milk affects its availability and cost. Thus, it is important to study a possible alternative ingredient to ensure the continuity of this traditional dessert. This project aimed to determine the physicochemical and sensory properties of ‘kuih bakar’ produced with coconut milk and soy milk. In the present study, ‘kuih bakar’ was prepared with fresh coconut milk (FCM) (positive control), fresh soy milk (FSM), commercial coconut milk (CCM), commercial soy milk (CSM), and without milk (negative control). Proximate analysis showed that substitution of coconut milk with soy milk reduced the fat and increased the protein content of ‘kuih bakar’ significantly (p < 0.05). However, the substitution of coconut milk did not show a significant effect (p > 0.05) on the colour properties and water activity of the sample. There were significant differences (p < 0.05) in scores during sensory evaluation between the samples but the ‘kuih bakar’ produced with FSM showed no significant difference (p < 0.05) as compared to FCM and CCM. This study demonstrated that physicochemical and sensory attributes of traditional ‘kuih bakar’ can be maintained by using FSM as a substitution of the traditional coconut milk used in producing ‘kuih bakar’.

scholarly journals FRAKSI ETANOL EKSTRAK KULIT DURIAN (Durio zibethinus L.) SEBAGAI ANTIFUNGI TERHADAP Trichophyton mentagrophytes DAN Candida albicans

1970 ◽  
pp. 28-38
Author(s):  
Yuli Wahyu Tri Mulyani ◽  
Subur Widodo ◽  
Lisa Selviani
Keyword(s):  
Candida Albicans ◽  
Antifungal Activity ◽  
Trichophyton Mentagrophytes ◽  
Inhibition Zone ◽  
Positive Control ◽  
Negative Control ◽  
Bark Extract ◽  
Chromatography Method ◽  
Durio Zibethinus ◽  
Ethanol Fraction

Durian is a fruit that is in demand by the community, but during durian season environmental problems arise due to waste from skin of durian. The aimed of the study was to prove the antifungal activity of the ethanol fraction of durian skin against Trichophyton mentagrophytes and Candida albicans and to determine the active active compounds inhibiting T. mentagrophytes and C. albicans fungi. Durian skin was extracted by maceration method, then fractionated used ethanol, chloroform, and n-hexane solvents. Ethanol fraction was tested on T. mentagrophytes and C. albicans fungi used the disc method with a concentration of 10%, 20%, 40%, 60%, 80%, 100%, distilled water as a negative control, ketoconazole as a positive control. The best inhibition zone is fungi T. mentagrophytes concentration 100% ( 9.23 mm) negative control (0 mm), positive control (32.96 mm), fungi C. albicans the best inhibition zone is concentration of 100% (8.30 mm), positive control (17.17 mm) negative controls (0 mm).The ethanol fraction was screened by the Thin Layer Chromatography method and positively contained flavonoids (rf 0.7), tannins (rf 0.58), saponins (rf 0.76) and alkaloids (rf 0.64). Minimum Inhibitory Concentrations of T. mentagrophytes were 7% and C. albicans were 8%. The most effective active compound growht of T. mentagrophytes is tannins (rf 0.7) and for C. albicans is flavonoid (rf 0.6). The ethanol fraction of durian bark extract has antifungal activity against T. mentagrophytes and C. albicans. Keywords: Antifungi, Candida albicans, ethanol fraction skin of durian, Trichophytonmentagrophytes

scholarly journals Uji Efektivitas Ekstrak Paku Pedang (Nephrolepis exaltata) Terhadap Pertumbuhan Jamur Candida albicans

2020 ◽  
Vol 13 (01) ◽  
pp. 33-38
Author(s):  
Diana Mey Merlina ◽  
Ngadiani
Keyword(s):  
Candida Albicans ◽  
Inhibition Zone ◽  
Positive Control ◽  
Negative Control ◽  
Treatment Groups ◽  
Randomized Design ◽  
Experimental Type ◽  
Spss Software ◽  
Negative Controls ◽  
Positive Controls

Plant swords (Nephrolepis exaltata) are ferns in the Lomariopsidaceae tribe which are easily found on the banks of rivers, cliffs, and contain flavonoids and alkaloids that can inhibit the growth of albicans candida fungi. This study aims to determine the effectiveness of Sword nail extract (Nephrolepis exaltata) on the growth of albicans candida fungi. This research is a quantitative laboratory experimental type using a completely randomized design (RAL) with 4 different treatment groups, 1 negative control (pz sterile) and 1 positive control (ketocenazole). The parameters observed were the number of colonies (CFU) and the average area of ​​the inhibition zone (mm). The data was analyzed using SPSS software using one way ANOVA analysis which was then followed by a test using DMRT. The results showed that all concentrations differed from the negative controls, while the extract concentration of 1000 ppm compared to the positive controls had no difference. Sword nail extract (Nephrolepis exaltata) has an influence on the growth of candida albicans mushrooms, namely the number of colonies of 6.78 CFU (6x106) at a concentration of 1000 ppm and inhibition zone 33.10 mm at a concentration of 1000 ppm.   Keywords : Candida albicans, Sword spikes (Nephrolepis exaltata), Inhibitory Zone, Colony Count.

IDENTIFIKASI SENYAWA METABOLIT SEKUNDER DAN UJI AKTIVITAS EKSTRAK ETANOL HERBA MENIRAN (Phyllanthus niruri L.) TERHADAP CANDIDA ALBICANS MENGGUNAKAN METODE DIFUSI CAKRAM

2017 ◽  
Vol 3 (1) ◽  
pp. 1
Author(s):  
Anita Apriliana ◽  
Eko Kusumawati ◽  
Selvitawati Selvitawati
Keyword(s):  
Candida Albicans ◽  
Ethanol Extract ◽  
Positive Control ◽  
Negative Control ◽  
Diffusion Method ◽  
P Value ◽  
Phyllanthus Niruri ◽  
Significant Difference ◽  
Agar Media ◽  
One Way Anova

The aim of this research is to know the ability of meniran ethanol extract (Phyllanthus niruri L.) in inhibiting the growth of Candida albicans. The research design is an experimental study. The extract used was herbal meniran extract made by maceration using 70% ethanol solvent, the content of ethanol extract of meniran tested against Candida albicans using disc diffusion method were 5%, 10%, 20%, 30% and 40%. Activity test conducted on Sabaraound Dextrose agar media that has been smeared with Candida albicans culture which has been standardized with Mc Farland standard. The pre-tested disc paper is first dipped into the extract with various concentrations. Incubated at 30 ° C for 24 hours and the inhibit zone formed was measured. The result showed that herbal ethanol extract of meniran resulted in drag zone diameter at Candida albicans ie 8,5 mm; 10.3 mm; 12.6 mm; 14.1 mm and 14.3 mm, for negative control 0 mm and positive control 20.1 mm. Data obtained from the results of the study were analyzed using one way anova method showed p - value <0,05, it was concluded that there was significant difference between negative control, 5%, 10%, 20%, 30%, 40% and positive control.

scholarly journals Uji Aktivitas Ekstrak Daun Pirdot (Sauraia vulcani Korth.) Terhadap Pertumbuhan Candida albicans Secara In Vitro

2020 ◽  
Vol 11 (1) ◽  
pp. 1
Author(s):  
Romauli Anna Teresia Marbun
Keyword(s):  
Candida Albicans ◽  
Dimethyl Sulfoxide ◽  
Leaf Extract ◽  
Skin Lesions ◽  
Positive Control ◽  
Negative Control ◽  
Control Group ◽  
Post Test ◽  
True Experiment

(Article History: Received 5 October 2020; Revised 8 October 2020; Accepted 15 October 2020) ABSTRAKJamur Candida albicans merupakan jamur penyebab kandidiasis dan penyebab sariawan, lesi pada kulit, vulvavaginistis, candida pada urin (kandiduria), dan gastrointestinal kandidiasis. Salah satu jenis tanaman yang berkhasiat sebagai obat yaitu pirdot (Sauraia vulcani Korth.) dan bagian yang biasanya digunakan adalah bagian daun. Tujuan penelitian ini adalah untuk mengetahui aktivitas ekstrak daun pirdot terhadap pertumbuhan C. albicans secara in vitro. Penelitian ini merupakan penelitian true experiment dengan rancangan penelitian post-test only control group. Metode yang digunakan adalah difusi agar menggunakan teknik kirby bauer. Penelitian ini menggunakan 4 variasi konsentrasi ekstrak daun pirdot, yaitu 10%, 20%, 40%, dan 80%, kontrol positif (tablet ketokonazol), dan kontrol negatif (Dimethyl Sulfoxide). Data yang diperoleh dianalisa menggunakan statistika secara deskriptif. Hasil penelitian menunjukkan daya hambat mulai dari konsentrasi 10% sebesar 8,96 mm daya hambat tertinggi pada konsentrasi 80% sebesar 18,33 mm. Kesimpulan ekstrak daun pirdot memiliki aktivitas antijamur terhadap C. albicans.Kata kunci: Antijamur; Candida albicans; Metode Difusi; Saurauia vulcani Korth. ABSTRACTCandida albicans is fungus that causes candidiasis and causes thrush, skin lesions, vulvavaginism, candidiuria and gastrointestinal candidiasis. One type of plant that has medicinal properties is pirdot (Sauraia vulcani Korth.) and the part that is usually used is the leaves. The purpose of this study was to determine the activity of pirdot leaf extract on the growth of C. albicans in vitro. This study was a true experiment with a post-test only control group research design. The method used agar diffusion using Kirby Bauer technique. This study used 4 variations concentration namely 10%, 20%, 40%, and 80%, positive control (ketoconazole tablets), and negative control (Dimethyl Sulfoxide). The data obtained were analyzed using descriptive statistical analysis. The results showed that the inhibitory from a concentration of 10% of 8.96 mm, the highest inhibition was at 80% of 18.33 mm. In conclusion, pirdot leaf extract has antifungal activity against C. albicans.Keywords: Antifungal; Candida albicans; Diffusison Method; Saurauia vulcani Korth

scholarly journals Effect of affordable disinfectant solutions on Candida albicans adhered to acrylic resin for dental prosthesis

2015 ◽  
Vol 63 (3) ◽  
pp. 309-314 ◽  
Author(s):  
Lina Naomi HASHIZUME ◽  
Murilo Fernandes HOSCHARUK ◽  
Maurício José Santos MOREIRA
Keyword(s):  
Hydrogen Peroxide ◽  
Candida Albicans ◽  
Sodium Hypochlorite ◽  
Culture Media ◽  
Low Cost ◽  
Acrylic Resin ◽  
Positive Control ◽  
Negative Control ◽  
Dental Prosthesis ◽  
Control Group

Objective: To evaluate the effect of different low-cost disinfectant solutions on Candida albicans (C. albicans) adhered to acrylic resin used in dental prosthesis. Methods: Sixty acrylic resin specimens were divided into four experimental groups according to the disinfecting agent tested (2% chlorhexidine, 1% sodium hypochlorite, vinegar and 10v hydrogen peroxide) and two control groups. Fifty specimens were incubated with C. albicans and after immersed in the disinfecting solutions or saline (negative control). Specimens without contamination constituted the positive control group. After disinfection procedures, all specimens were immersed in a culture medium and incubated for 24 hours at 37°C. Culture media turbidity was evaluated. Results: The disinfectants 2% chlorhexidine and 1% sodium hypochlorite performed a maximal reduction of C. albicans. Vinegar showed intermediate antifungal effect and 10v hydrogen peroxide showed a lower effect. Conclusions: Among the disinfecting solutions tested in the present study, 2% chlorhexidine and 1% sodium hypochlorite are the most effective in the reduction of C. albicans adhered to acrylic resin. However, vinegar may represent a viable and low-cost alternative to prosthesis disinfection.

Sign in / Sign up

Export Citation Format

Share Document