scholarly journals The use of the drug "Dextranal" to stimulate cellular immunity and prevention of gastrointestinal diseases calves

2021 ◽  
Author(s):  
I.N. Penkova ◽  
N.Y. Balybina ◽  
V.Y. Koptev ◽  
N.A. Shkill ◽  
M.A. Leonova ◽  
...  
Keyword(s):  
Cellular Immunity ◽  
Clinical Signs ◽  
Live Weight ◽  
Gastrointestinal Diseases ◽  
Phagocytic Index ◽  
Control Group ◽  
Maximum Increase ◽  
Instructions For Use ◽  
Experimental Group ◽  
Newborn Animals

The article provides data on the preventive efficacy of the drug "Dextranal" in gastrointestinal diseases of calves and pigs, as well as the effect of the drug on the resistance of newborn animals. Calves and piglets of the experimental groups were injected with the drug from the first day of life, 5 injections at different intervals, depending on the group. During the experiment, the animals were clinically examined daily. When symptoms of gastrointestinal or respiratory tract lesions appeared, clinical signs and duration were recorded. All sick calves, regardless of the group, were prescribed the use of the antibiotic "Dorin-R" in a dosage according to the instructions for use. The shortest duration of the disease was noted in the calves of the first experimental group that received Dextranal at a dose of 0.06 mg / kg (3.0 ml) with an interval of 3 days. This prophylaxis scheme reduces the duration of the disease in animals by 15% compared to the control group. The analysis of the results of the opsonophagocytic reaction (OFR) indicates an increase in the parameters of the phagocytic index, phagocytic number and phagocytic activity of the blood of animals of the experimental groups, which indicates the direct effect of the drug on cellular immunity. The maximum increase in live weight is observed in calves of the first experimental group, exceeding the same indicator of control by 7.4%. When using the drug "Dextranal" to piglets at a dose of 0.02 mg / kg with an interval of 4 days, there is a decrease in animal mortality by 4%. Also, when using the drug according to this scheme, the piglets of the experimental group on the 14th and 42nd days have a maximum increase in live weight in comparison with the same indicator in the control group.

MONIZEN FORTE FOR LAMBS PARASIT-IC DISEASES

2020 ◽  
Vol 2 ◽  
pp. 84-87
Author(s):  
E. S. Engasheva ◽  
◽  
V. I. Kolesnikov ◽  
Keyword(s):  
Clinical Signs ◽  
Live Weight ◽  
Control Group ◽  
Not Given ◽  
The North ◽  
Condi Tions ◽  
High Infection ◽  
Mucous Discharge ◽  
And Control ◽  
Experimental Group

The Monizen Forte test for parasitic sheep diseases was tested under production condi-tions on 460 lambs of the North Caucasian breed, with a live weight of 25-30 kg, with high infection with nematodes, cestodes and larvae of the nasopharyngeal gadfly (Oestrus ovis), which were given orally in a mixture with half the normal rate of concentrated feed, the test drug in a dose of 1 ml per 20 kg of the animal weight. Experienced (20 ani-mals) and control (10 animals) groups of lambs with an average live weight of 28 kg were selected from these lambs according to the principle of analogues. To the lambs of the control group, the drug was not given. 10 days after administration of the drug by clini-cal and coprological studies, it was found that the lambs of the experimental group, the intensity of nematode invasion decreased and the drug’s intensity (IE) was 96.7%, and the extensivity (EE) was 95%. The lambs of the experimental group before the introduction of the drug were 40% invaded with moniesia and 50% dictiocauli, and after using Monizen Forte they were released - the ex-tensibility (EE) was 100%. Lambs of the control (untreated) group, the intensity and extent of infection with nematodes and ces-todes remained at the same level as at the beginning of the experiment. All 10 lambs (50%) of the experimental group, the clinical signs of estrosis (sneezing, snorting, serous-mucous discharge from the nose) disap- peared, and the lambs of the control group have these clinical signs persisted.

scholarly journals ВПЛИВ КОРМОВИХ ДОБАВОК НА ПРОДУКТИВНІСТЬ, ГЕМАТОЛОГІЧНІ ТА ІМУНОЛОГІЧНІ ПОКАЗНИКИ КРОВІ КУРЧАТ–БРОЙЛЕРІВ

2016 ◽  
Vol 18 (3(70)) ◽  
pp. 157-161
Author(s):  
H.I. Kotsumbas ◽  
М.І. Hryniv
Keyword(s):  
Broiler Chickens ◽  
Live Weight ◽  
Liquid Solution ◽  
Feed Additives ◽  
Recommended Dose ◽  
Phagocytic Index ◽  
Control Group ◽  
Broiler Chicks ◽  
Immunological Parameters ◽  
Experimental Group

The results of the influence of feed additives: acidulent Versal liquid and probiotic bifidobacteria PKB on the growth dynamics and some hematological and immunological parameters of broiler chickens are presented in this article. The research was conducted on 30 broiler chicks. There were formed 3 groups. There were 10 chicks in each of them: a control group didn't get any feed additives; 1–st experimental group got feed and acidulent Versal liquid solution at the recommended dose of 1 ml /1 l of water; 2–nd experimental group got feed with probiotics bifidobacteria PKB at the recommended dose of 1g / 1kg of feed and acidulent Versal liquid solution at the recommended dose of 1 g/1 l of water. The 15th and 30th day blood were collected for hematological and immunological parameters checking.It was found, chicks that have got feed additives achieved more intensive increasing of average live weight and daily gain during this period. The live weight of broiler chicks from the second experimental group was higher at 76.5 grams, compared with the control and the 136.6 h – compared with I research group in case of using acidified and probiotics bifidobacteria. Average daily increasing were 49.93 g in the control group, 48.21 g and 52.36 g according to another experimental groups. There was a tendency of hemoglobin increasing on the 30–th day of experiment in all experimental groups. The hemoglobin concentration increased by 1.09 times in the 1–st group and in 1,20 times in the 2–nd group. The number of leukocytes was increased in the experimental group. It was also increased by 16.6% in the 1–st group and by 44.4% in the 2–nd group. Phagocytic activity of pseudo eosinophils increased in all experimental groups on the 30–th day of the feed additives using. The most important increasing by 7.2% was in the 2–nd group. There was also a tendency of the phagocytic index increasing in all experimental groups of chicks on the 30–th day of this investigation. It was established that the using of acidulent and PKB probiotic preparation of food at feeding broilers improves hemoglobin levels. It also promotes to leukocytosis, phagocytic pseudo eosinophils activity and improves the overall condition and immunological reactivity. 

The drug Argovit for treatment of piglets when intestinal infections

2021 ◽  
pp. 22-30
Author(s):  
V. I. Raitskaya
Keyword(s):  
Live Weight ◽  
Gastrointestinal Diseases ◽  
The Body ◽  
Farm Animals ◽  
Control Group ◽  
Basic Drug ◽  
Treatment And Prevention ◽  
Intestinal Infections ◽  
Inflammatory Processes ◽  
Experimental Group

The drug Argovit developed in the LLC Vector-Vita Research and Production Center has antimicrobial and astringent properties, easily fits into the technology of housing farm animals and poultry in cases of uncomplicated colibacteriosis and is effective in isolated use, it is cheaper than other drugs, which makes it attractive in the modern market of biological products. The purpose of the research was to study the effectiveness of the drug Argovit for the treatment and prevention of gastrointestinal diseases of piglets in comparison with the basic drug Baitril used in the farm. Piglets of the experimental group (n=20) with the syndrome of gastrointestinal diseases have been treated with 1,0 % aqueous solution of the drug Argovit at a dose of 2 ml/kg of live weight 2 times a day until clinical recovery. The drug contributed to a lighter course and reduced the duration of the disease by half, while the livability of piglets reached 90,0 %. There was also a weakening of inflammatory processes in the body of piglets of both groups, which was characterized by the decrease in the level of leukocytes in piglets of the experimental group during treatment from 12,9±0,75 to 10,1±0,89×10⁹/l, and in the control group from 11,3±1,20 to 9,0±0,04×10⁹/l. The platelet content in animals at the beginning of the experiment was slightly higher than the lower limit of the norm in the experimental group by 1,8 %, in the control group by 4,7 %. At the same time, the restoration of homeostasis and the decrease in the level of protein in the blood serum have been observed. It has been found that the use of the drug Argovit to piglets during the suckling period and after weaning improves the morphological and biochemical parameters of blood due to the protective forces of protein by 4,7 %, reduces the phenomena of diarrhea, and as a result increases their livability.

scholarly journals Use of probiotic lactobacilli to increase non-specific resistance and productivity of rabbits

2020 ◽  
Author(s):  
A.N. Ovcharova ◽  
Keyword(s):  
Growth Rate ◽  
Bactericidal Activity ◽  
Phagocytic Activity ◽  
Specific Resistance ◽  
Live Weight ◽  
Phagocytic Index ◽  
Control Group ◽  
Control Parameters ◽  
Probiotic Lactobacilli ◽  
Experimental Group

The article presents the results of the effectiveness of probiotic lactobacilli on the productivity and non-specific resistance of rabbits. The phagocytic activity of neutrophils increased by 10 %, which turns out to be statistically significant. The bactericidal activity of blood increased by 8 % in comparison with the control group; the phagocytic index was also higher in the experimental group by 2.02. The content of lysozyme in the blood serum of rabbits in the experimental group was significantly higher than the control parameters by 18.6 micrograms/ml. As tentative results, we report an increase in the live weight and growth rate in the experimental group of rabbits.

scholarly journals Complex Food Supplement for Calves

2020 ◽  
Author(s):  
О.Б. Филиппова ◽  
А.И. Фролов ◽  
Н.И. Маслова ◽  
А.Н. Бетин
Keyword(s):  
Average Daily Gain ◽  
Live Weight ◽  
Gastrointestinal Diseases ◽  
Food Supplement ◽  
Feed Additives ◽  
Total Leukocyte Count ◽  
Economic Damage ◽  
Control Group ◽  
Gastrointestinal Pathology ◽  
Experimental Group

Одной из главных причин, тормозящих полное сохранение нарождающегося молодняка – массовые желудочно-кишечные заболевания, особенно телят, которые имеют широкое распространение, наносят значительный экономический ущерб и вызывают большой отход. У молодняка первых дней жизни наблюдают физиологический дисбактериоз, который часто сочетается с иммунодефицитом, что делает их особо уязвимыми к желудочно-кишечной патологии. Несмотря на то, что в профилактике диспепсии телят достигнуты определённые успехи, эта проблема ещё далека от своего полного решения. Поэтому разработка улучшенной технологии полноценного кормления телят в первую и последующие фазы постнатального онтогенеза с использованием в рационах импортозамещающей фитоферментной кормовой добавки является актуальной, физиологичной и перспективной, представляющей интерес для науки и производства. За счёт введения в фитоферментную добавку органических форм селена и цинка их содержание в среднесуточном рационе телят опытной группы превышало на 42 и 78% соответственно по сравнению с контролем. Затраты энергии и переваримого протеина на 1 кг прироста у телят опытной группы были меньше на 6,9 и 4,3% соответственно, чем у контрольной группы. Различие в среднесуточном приросте живой массы между группами сохранилось и составило 7,7% в пользу животных опытной группы. В группе опытных животных болели два телёнка с 4-суточного возраста, с продолжительностью болезни 4 суток. Для лечения животных контрольной группы было израсходовано ветеринарного препарата Энронит на сумму 66 руб./гол. Более высокий показатель неспецифического клеточного иммунитета наблюдался в опытной группе телят, в крови которых общая сумма лейкоцитов была выше на 11,8%. Дополнительный доход от условной реализации молодняка опытной группы на 608,5 руб. больше (+26,3%), чем контрольной, при сокращении заболеваемости животных (на 34%) и меньших затратах энергии на 1 кг прироста (–6,9%). One of the main reasons hampering the full conservation of the emerging young is the massive gastrointestinal diseases especially in calves which are widespread and cause significant economic damage and cause a big mortality. In young animals of the first days of life physiological disbacteriosis is observed which is often combined with immunodeficiency which makes them especially vulnerable to gastrointestinal pathology. Despite the fact that certain successes have been achieved in the prevention of calf dyspeptic disorder this problem is still far from its full solution. Therefore the development of an improved technology for the complete feeding of calves in the first and subsequent phases of postnatal ontogenesis using import substituting phytoenzymatic feed additives in the rations is actual, physiological, promising and having a considerable scientific and production interest. Due to the introduction of organic forms of selenium and zinc into the phytoenzymatic supplement their content in the average daily diet of calves of the experimental group exceeded 42 and 78% respectively compared with the control. The costs of energy and digestible protein per 1 kg of gain in calves of the experimental group were 6.9 and 4.3% less respectively than in the control group. The difference in the average daily gain in live weight between the groups remained and amounted to 7.7% in favor of the animals of the experimental group. In the group of experimental animals two 4 day old calves were sick with disease duration of 4 days. For the treatment of animals of the control group the veterinary preparation Enronit was spent in the amount of 66 rubles / goal. A higher rate of nonspecific cellular immunity was observed in the experimental group of calves, in the blood of which the total leukocyte count was 11.8% higher. Additional income from the conditional sale of young experimental group was of 608.5 rubles more (+ 26.3%) than the control one with a reduction in the incidence of animals (34%) and lower energy costs per 1 kg of gain (–6.9%).

Influence of DAFS-25+polizon composition on blood and functional state of liver of steers at fattening

2020 ◽  
pp. 15-18
Author(s):  
Inna R. Kilmetova ◽  
◽  
Igor A. Rodin ◽  
Nazira I. Khayrullina ◽  
Nikolay G. Fenchenko ◽  
...  
Keyword(s):  
Functional State ◽  
White Blood Cells ◽  
Live Weight ◽  
The Body ◽  
Farm Animals ◽  
Control Group ◽  
Standard Diet ◽  
The Impact ◽  
Experimental Group ◽  
Stimulation Of

Summary. The disbalanced feeding and the uneven distribution of micro- and macroelements in the environment leads to a trace element, in particular hypomelanosis. To accelerate the growth and preservation of young farm animals include in the diet of various biological additives and drugs, which include selenium. For stimulation of weight gain in the livestock industry, as well as for the prevention and treatment of pathological processes in addition to micro - and macrouse amino acids, primarily methionine. The aim of this work was to study the influence of composition of DAFS-25+Polizon on morpho-biochemical parameters of blood and functional state of the liver in fattening bulls of black-motley breed in the conditions of the Republic of Bashkortostan. Experiments using were conducted on bull-calves of black-motley breed of the properties in the properties age from 6 to 15 months. The first experimental group during the experiment was additionally given the composition of DAFS-25+Polizon at a dose of 2 mg/kg, the animals of the control group received a standard diet. To assess the impact of the composition DAFS-25+Polizon on metabolism cattle studied morphological and biochemical indicators of blood and conducted histological examination of the liver. It is established that the use of the composition of DAFS-25+Polizon at a dose of 2 mg/kg increases the number of erythrocytes and hemoglobin in the experimental group and reduces the amount of white blood cells. The serum content of total protein, phosphorus and calcium increases in the group of experimental animals. Microscopic examination of the liver revealed no changes in the structure of the organ and hepatocytes in the experimental group, whereas in the control group hemodynamic disorders and dystrophic changes in liver cells were observed. Thus, the use of the composition DAFS-25+Polizon at a dose of 2 mg/kg of live weight in fattening bulls black-and-white breed contributes to the increase of redox processes in the body, stimulation of metabolism, prevent the development of liver disorders of cellular mechanisms of metabolism, optimizes the structure of the liver, which generally provides higher productivity.

Local mineral feed additives in the rations of steers of Hereford breed

2020 ◽  
pp. 28-39
Author(s):  
M. Grigoryev ◽  
N. Chernogradskaya
Keyword(s):  
Economic Effect ◽  
Live Weight ◽  
Negative Influence ◽  
Feed Additives ◽  
The Body ◽  
Control Group ◽  
Mineral Salts ◽  
Meat Productivity ◽  
Experimental Group ◽  
Mineral Feed Additives

Animals imported to Yakutia from other regions fall into feeding and housing conditions that differ from their usual agro-climatic conditions, which causes the problem of their adaptation. Yakutia is one of the areas where the feed of its own production has a lack of basic minerals, which affects the health and productivity of animals, which has an additional negative influence on the adaptation process of imported cattle. In order to replenish macro- and microelements in the body, it is necessary to introduce various local mineral feed additives, premixes, and use mineral salts into the ration. Under the conditions of Central Yakutia the influence of local mineral feed additives (zeolite of the Khonguruu Deposit in the Suntar district and sapropels of local lakes) containing macro- and microelements that increase the meat productivity of steers has been studied. As a result of the research the influence of local mineral feed additives on meat productivity and physiological condition of Hereford steers has been established. Influence of zeolite and sapropel in a complex with mineral salts on digestibility of nutrients of the ration and use of nitrogen, calcium and phosphorus by experimental animals has been defined. The influence of feed additives on the quality of meat products has been studied. The results have shown that the use of local mineral feed additives in the composition of ration of steers during the fattening period at a dose of 0,7 g zeolite per 1 kg of live weight of the animal and 200 g of sapropel in combination with 10 g of mineral salts contributed to the gain in live weight, carcass weight, carcass yield, yield of edible parts, and economic efficiency of fattening. For the entire period of the experiment the gain in live weight in groups was: in control group 2222,9 kg, in the 1st experimental group 2396,2 kg, in the 2nd experimental group 2471,1 kg. The total economic effect for the 1st experimental group for the period of experiment amounted to 44,3 thousand Rubles, for the 2nd experimental group 78,0 thousand Rubles or per 1 head/day 14,06 and 24,76 Rubles, respectively.

The effectiveness of use of enterosorbent Shelltic Es when rearing of young pigs

2020 ◽  
pp. 3-11
Author(s):  
S. Grikshas ◽  
N. Kulmakova ◽  
K. Spitsyna ◽  
A. Dar’in ◽  
T. Mittelshtein
Keyword(s):  
Average Daily Gain ◽  
Live Weight ◽  
Feed Additives ◽  
The Body ◽  
Control Group ◽  
Internal Organs ◽  
Feed Digestibility ◽  
Young Pigs ◽  
Carcinogenic Effects ◽  
Experimental Group

Mycotoxins have been formed in feed are secondary metabolites of fungi and are quite stable substances that have teratogenic, mutagenic and carcinogenic effects. An effective way to combat mycotoxins in feed is the use of feed additives that adsorb toxins, prevent their absorption in the gastrointestinal tract of the animal and are excreted from the body. The infl uence of coconut enterosorbent Shelltic Es on fattening and meat qualities of young pigs has been studied. It has been found in the process of fattening that the highest feed digestibility was in pigs of the experimental group, in the diet of which enterosorbent has been added. The results of studies of the chemical composition and technological properties of pork have been provided. The positive eff ect of enterosorbent on precocity, absolute average daily gain of live weight and reduction of feed expenditures per 1 kg of gain has been revealed. In pigs from the experimental group the average thickness of the fat was higher and the area of the “muscle eye” was lower compared with animals of the control group, which indicates that higher rates of carcass yield have been obtained due to faster accumulation of fat tissue. The weight of internal organs of pigs indicates the intensity of metabolic processes in the body. In experimental animals the weight of the lungs was 0,1 kg lower, and the liver and heart were higher by 0,13 and 0,01 kg, respectively. Enterosorbent had no effect on the content of vitamins in the liver of pigs of the compared groups. The content of impurities of organochlorine toxicants and toxic elements in the meat and liver of animals of the experimental group was lower than that of control analogues. Therefore, the use of enterosorbent Shelltic Es promotes more active excretion of them from the body.

USING THE KAZAKH WHITE-HEADED BREED TO INCREASE BEEF IN THE FLAT PROVINCE OF DAGESTAN

2020 ◽  
Author(s):  
М.М. САДЫКОВ ◽  
М.П. АЛИХАНОВ ◽  
А.Г. СИМОНОВ ◽  
Г.А. СИМОНОВ
Keyword(s):  
Growth And Development ◽  
Live Weight ◽  
Control Group ◽  
Beef Production ◽  
Daily Growth ◽  
Carcass Yield ◽  
Breeding Stock ◽  
Fattening Period ◽  
The Cross ◽  
Experimental Group

Изучены рост и развитие бычков — помесей красной степной с казахской белоголовой породой в равнинной провинции Дагестана. Установлено, что помесный молодняк, по сравнению с чистопородным скотом красной степной породы, имеет более высокую живую массу при рождении на 1,8 кг, или 7,3%. При отъеме в 8-месячном возрасте помеси имели живую массу 210 кг против 187,6 кг у красного степного молодняка, что на 22,4 кг, или 11,9% выше. В 12-, 15- и 18-месячном возрасте живая масса помесных бычков равнялась 291,8 кг, 359,7 и 436,6 кг, соответственно, или на 28 кг, 36 и 45,8 кг больше по сравнению с красным степным скотом. Среднесуточные приросты помесных бычков за период выращивания и откорма составили 760 г, что выше на 12,1% по сравнению с чистопородным красным степным молодняком. После заключительного откорма и убоя помесные бычки дали тяжеловесные туши с хорошим поливом. По массе парной туши они превосходили чистопородных аналогов на 31,3 кг, или 15,6% с преимуществом выхода туши на 2,4%. Убойный выход у бычков опытной группы составил 58,7%, контрольной — 55,8%. От помесных бычков были получены тяжеловесные шкуры массой 27,1 кг, от чистопородных — 21,6 кг, преимущество по этому показателю имели помесные животные 5,5 кг, или 25,4%. Для увеличения производства говядины в равнинной провинции Дагестана рекомендуем скрещивание коров красной степной породы с быками казахской белоголовой породы. The growth and development of bulls of red steppe crossbreeds with the Kazakh white-headed breed in the flat province of Dagestan were studied. It was found that young crossbreed animals in comparison with purebred red steppe cattle have a higher live weight at birth by 1,8 kg or 7,3%. When weaning at 8 months of age, cross-bred bulls had a live weight of 210 kg against 187,6 kg in red steppe young, which is 22,4 kg, or 11,9% higher. At 12, 15 and 18 months of age, the live weight of crossbred bulls was 291,8 kg, 359,7 and 436,6 kg, respectively, or 28 kg, 36 and 45,8 kg more than the red steppe cattle. The average daily growth of cross-bred bulls during the growing and fattening period was 760 g compared to 678 g, that is, they were 12,1% higher compared to purebred red steppe young. After the final fattening and slaughter, the cross-bred bulls gave heavy carcasses with good watering. By weight of the paired carcass, they were superior to purebred counterparts by 31,3 kg or 15,6% with an advantage of 2,4% carcass yield. The slaughter yield of bulls in the experimental group was 58,7%, 55,8% in the control group, respectively, with an advantage in favor of crossbreeds of 2,9%. Heavy skins weighing 27,1 kg were obtained from crossbreed bulls, 21,6 kg from purebred ones, and crossbreed animals of 5,5 kg or 25,4% had an advantage in this indicator. Studies have shown that in order to increase beef production in the lowland province of Dagestan, it is necessary to use crossbreeding of the breeding stock of the red steppe breed with bulls of the Kazakh white-headed breed.

ORGANIC ACIDS IN FEEDING OF PIGS AND THEIR EFFECT ON PRODUCTIVITY AND CLINICAL AND PHYSIOLOGICAL STATE

2018 ◽  
Vol 1 (2) ◽  
pp. 84-88
Author(s):  
L. A. Nikanova ◽  
Keyword(s):  
Organic Acids ◽  
Orthophosphoric Acid ◽  
Physiological State ◽  
Average Daily Gain ◽  
Initial Dosage ◽  
Live Weight ◽  
Feed Additive ◽  
Control Group ◽  
Daily Gain ◽  
Experimental Group

The influence of feed additive "Ormik" consisting of organic acids (formic acid, lactic acid, orthophosphoric acid, acetic acid), as a filler of diatomite crumb, introduced into concentrated fodders, on the biochemical parameters of blood serum of pigs and on productivity is considered in the article. The studied feed additive was added to the feed daily in the form of loose powder, mixing thoroughly. The initial dosage of the feed additive in the 1st week was 1 g/kg of feed, 2nd week and the following – 3 g/kg of feed. The average daily gain in the live weight of pigs in the experimental group was 11,0% higher than the control group. The animals of the experimental group were less sick and the safety of this group was 100%, in the control group it was 90%.

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