The effect of ethanol on some hematological parameters of the australian red claw crayfish (Cherax quadricarinatus)

2022 ◽  
pp. 85-91
Author(s):  
D. Skafar ◽  
D. Shumeyko
Keyword(s):  
Body Weight ◽  
Total Protein ◽  
Hematological Parameters ◽  
Group Versus ◽  
Control Group ◽  
Total Protein Content ◽  
Cherax Quadricarinatus ◽  
Total Hemocyte Count ◽  
Red Claw Crayfish ◽  
Experimental Group

Purpose: to study the effect of ethanol on the parameters of THC, the percentage of granulocytes and total protein in the hemolymph of the Red claw crayfish (Cherax quadricarinatus).Materials and methods. The object of this experiment was 26 males of the Australian red-clawed crayfish (Cherax quadricarinatus) weighing from 23 to 83 g. The individuals were evenly divided into two experimental groups - with an injection of ethanol and a control group without an injection of 13 crayfish for each group. The injection dose was 2515 mg per 100 g of body weight. A day after the introduction of ethanol, hemolymph was taken with a syringe from the ventral sinus, the syringe was pre-washed with a 4% EDTA-Na2 solution. Three parameters were determined: the total hemocyte count (THC), percent granulocytes and percent total protein content. Counting of hemocytes and determination of granulocytes were performed in a Goryaev chamber under a light microscope. The total protein was determined by the refractometric method.Results. Differences in THC and total protein between the groups were statistically unreliable (p>0,05). THC in the experimental group is 36% more than in the control group. The total protein after the introduction of ethanol actually increased by 0,7%, and relatively by 14%. There were statistically different indicators of the proportion of granulocytes (p<0,05) - the average value of 33,1% in the experimental group versus 24,5% in the control group. A reliable (p<0,05) strong feedback was revealed between the total protein and the mass of individuals in both experimental groups, while in the experimental group there is a visible shift in the values of dependent hemolymph indicators towards an increase in smaller individuals.Conclusion. A single injection of ethyl alcohol with a dosage of 2515 mg per 100 g of body weight into the hemolymph of C. quadricarinatus does not cause significant changes in the THC and total protein after 24 hours. At the same time, the proportion of granulocytes actually increases by 9%, relative to 37%. This may indicate that granulocytes are involved in the formation of cancer defense mechanisms when exposed to toxic substances. The effect of different dosages of ethanol injections and the duration of its effect on hematological parameters requires additional consideration. It is necessary to investigate its effect on other indicators, such as the pH and buffer capacity of the hemolymph, the concentration of hemocyanin, glucose, lactates and calcium.

Effects of feeding level and starvation on growth and water and protein content in juvenile redclaw crayfish, Cherax quadricarinatus (von Martens)

1996 ◽  
Vol 47 (5) ◽  
pp. 745 ◽  
Author(s):  
H Gu ◽  
AJ Anderson ◽  
PB Mather ◽  
MF Capra
Keyword(s):  
Body Weight ◽  
Protein Content ◽  
Water Content ◽  
Total Protein ◽  
Simultaneous Increase ◽  
Total Protein Content ◽  
Body Protein ◽  
Cherax Quadricarinatus ◽  
Feeding Level ◽  
Loss Of Weight

Effects of feeding level and starvation on growth, water content and protein content were examined in juvenile Cherax quadricarinatus. Gain in body weight was positively related to feeding level. An increase in feeding level resulted in a decrease in water content and an increase in protein content. Although the majority of juveniles were able to tolerate starvation for at least 12 days, deprivation of feeding caused a loss of weight and a gradual decrease in protein content combined with a simultaneous increase in water content. Total protein content was reduced by 3.9% in juveniles starved for three days and by 8.3% in those starved for 12 days. Normal body protein content, however, was recovered within six days after subsequent feeding in juveniles that were deprived of food for 12 days.

scholarly journals State of protein and mineral exchange in broiler-chickens for the use of Zinc and Mangane chelates

2019 ◽  
pp. 85-94
Author(s):  
V. Sakara ◽  
A. Melnyk ◽  
F. Markhenkov
Keyword(s):  
Total Protein ◽  
Broiler Chickens ◽  
Zinc Content ◽  
Calcium Content ◽  
Inorganic Phosphorus ◽  
The Body ◽  
Control Group ◽  
Total Protein Content ◽  
Total Calcium ◽  
Experimental Group

The results of the application of a complex of Zinc and Manganese chelates to protein, macro- and micro-mineral exchanges in the body of broiler chickens of the Cobb 500 cross-breed are presented. The administration of Zn and Mn chelates in a dose of 0,2 ml/l for chicken broilers of 23 days of age (1st experimental group) during 14 days influenced the increase in the total protein content to 35,3±0,8 g/l, which is 8 % higher compared with the control – 32,5±0,7 g/l (p<0,01 ) The concentration of total Calcium in serum of broiler chickens 37-day-old (end of trial) was higher in the first experimental group by 7,3 % (2,05±0,06 mmol/l) compared to control – 1,9±0,03 mmol/l. In the second group, where chelates were administered in a dose of 0,4 ml/l of water, the Calcium content was 2,0±0,02 mmol/l, which is 5 % more than the control group. The two-week application of Zn and Mn chelates also led to an increase in the level of inorganic Phosphorus in the serum of the first group to 2,6±0,12 mmol/l (+ 11,5 %) compared with the control group. After administration of chelates Zn and Mn at doses of 0,2 ml/l water, the Zinc content was higher by 4,3% (23,5±0,2 μmol/l) compared to control – 22,5±0,34 μmol/l (p<0,01). In the second group, where the dose of chelates was 0,4 ml/l, the concentration of Zinc was 23,6±0,16 μmol/l, which is more than 4,6 % for control (p<0,01). At the end of the study, the content of Manganese in serum of broiler chickens in the first group was 1,9±0,07 μmol/l (p<0,05), which is 10,4% higher compared with the control – 1,7±0,06 μmol/l (3rd sampling). The level of this element in the second group was 2,0±0,08 μmol/l (p<0,01), which is higher by 16,7 % relative to the control. At the end of the experiment, the coupon concentration in the first and second experimental groups was 12,6 and 9,3 % higher, compared with control, 7,0±0,37 μmol/l. In turn, the serum Ferrum content of the first group was greater by 9,3 % (19,3±0,69 μmol/l), and the second by 6,7 % (18,8±0,47 μmol/l) compared to the bird of the control group. Key words: chicken broilers, chelates, Zinc, Manganese, Cuprom, Ferrum, metabolism.

scholarly journals Protein-synthesizing function and functional state of the liver of dogs at experimental toxocariasis

2020 ◽  
Vol 22 (98) ◽  
pp. 132-137
Author(s):  
W. S. Said ◽  
V. V. Stybel ◽  
B. V. Gutyj ◽  
O. B. Pryima ◽  
I. Y. Mazur
Keyword(s):  
Body Weight ◽  
Functional State ◽  
Total Protein ◽  
Aspartate Aminotransferase ◽  
Alanine Aminotransferase ◽  
Experimental Studies ◽  
Control Group ◽  
Activity Of Enzymes ◽  
Experimental Group

The aim of the study was to investigate the effect of toxocariasis invasion on protein-synthesizing function and functional state of the liver of dogs. For experimental studies, 12 dogs aged from two to four months were used and two groups of six animals were formed in each: control and experimental. Puppies of the experimental group were experimentally infected with the pathogen toxocariasis at a dose of 5,000 invasive eggs of T. canis per kg of body weight. The control puppies were clinically healthy. Protein-synthesizing function of the liver of dogs in experimental toxocariasis was studied by the level of total protein and its fractions. It was found that on the 25th day of the experiment the level of total protein in the blood of the experimental group of dogs was 56.9 ± 1.47 g/l, while in the control group – 63.8 ± 2.92 g/l. The lowest level of the studied indicator was on the 30th day of the experiment in the blood of the experimental group of dogs, where it decreased by 9.6 %. The results of a study of protein fractions in the blood of dogs infested with toxocara showed that the percentage of albumin is likely to decrease. However, in the blood of infected dogs in this period of research there was a probable increase in globulin levels. The study of the effect of toxocariasis invasion on the activity of enzymes in blood serum is a test for the morphological and functional state of tissues and organs. Based on the studies, it was found that with the development of toxocariasis invasion in dogs there is an increase in alanine aminotransferase in their serum. On the 25th and 30th day of the experiment, the activity of the enzyme in the serum of infected dogs was the highest, where compared with the control group of dogs, the activity of ALT increased by 51.2 and 59.1 %, respectively. Similar changes in activity were observed in the determination of aspartate aminotransferase, where, respectively, on the 15th, 20th and 25th day of the experiment, the activity of AST in the serum of infected dogs increased by 19.3, 27.5 and 39.1 %.

scholarly journals The effect of herbal phytoextract on metabolic parameters of sows and piglets

2021 ◽  
Vol 22 (3) ◽  
pp. 428-435
Author(s):  
A. A. Ivanovsky ◽  
N. A. Latushkina ◽  
E. Yu. Timkina
Keyword(s):  
Total Protein ◽  
Biochemical Parameters ◽  
Control Group ◽  
Total Protein Content ◽  
Herbal Extracts ◽  
Control Groups ◽  
Normal Range ◽  
Experimental Group ◽  
Experimental Pigs

The purpose of the research was to study the effect of a phytocomplex containing herbal extracts of R. carthamoides, S. coronata, F. ulmaria on blood biochemistry of milking sows, the development and viability of piglets born by the time of weaning. For the experiment, the animals were divided into an experimental (Phytoadditive) and a control (SPK-2 compound feed) groups, 10 animals each. Phytoadditive in dry form was introduced into the diet of pigs of the experimental group during the sucking period (30 days) daily, once per head per day - 10 grams (individually). Before the beginning and at the end of the experiment, the blood of sows was examined for biochemical parameters. The multiplicity, the quality of the piglets born, the weight of the nest and one pig after birth and before weaning, as well as viability were determined. As the result, it was found that the concentration of the investigated extractives in the Phytoadditive was 13.5 g/kg, of which 10.5 g were ecdysteroids and 3.0 g of flavonoid rutin. Significant changes in the total protein content in the blood compared with the beginning of the experiment were noted in experimental pigs from 60.2±0.5 to 67.3±0.2 g/l (P <0.05) and in the control group from 61.0±0.2 to 66.1±0.1 g/l (P <0.05), the "Ca" content from 2.1±0.01 to 2.7±0.02 mmol/l (P <0.05) in the experimental group and from 2.0±0.01 to 2.5±0.02 mmol/l (P <0.05) in the control groups, while being within the normal range. The amount of albumin significantly increased only in the experimental group from 40.8±1.2 to 49.3±2.8 g/l (P <0.05), in the control from 42.2±2.1 to 46.0±1.5 g/l (P> 0.05). The number of piglets with low viability in the experimental group was 2 times less than in the control group. The viability of piglets in the experimental group by the time of weaning was 92.6 %, in the control ‒ 83.2 %.

scholarly journals Protein synthesize function of bulls liver at experimental chronic cadmium toxicity

2019 ◽  
Vol 21 (94) ◽  
pp. 92-96 ◽  
Author(s):  
Y. Y. Lavryshyn ◽  
B. V. Gutyj
Keyword(s):  
Body Weight ◽  
Total Protein ◽  
Cadmium Chloride ◽  
Cadmium Toxicity ◽  
The Body ◽  
Control Group ◽  
Black And White ◽  
Wide Range ◽  
Inflammatory Processes ◽  
Experimental Group

The article presents the results of studies on the influence of cadmium load on the body of young cattle. The adverse effect of Cadmium on the liver causes a wide range of pathological changes at various levels of its organization. The purpose of the work was to investigate protein synthesize function on the liver of bulls for experimental chronic cadmium toxicity. The research was carried out on the basis of a farm at the village Ivanivtsi, Zhydachiv district of Lviv region, on 10 bulls of six months old, Ukrainian black-and-white milk breed, which were formed in 2 groups of 5 animals in each: control and experimental. Bulls of the control group were in the usual diet. Bulls of the experimental group were fed with forage with cadmium chloride at a dose of 0.04 mg/kg body weight of the animal. The research lasted for 30 days. Protein synthesize function of the liver was determined by the level of serum total protein and protein fractions. It was established that when feeding cows with feed of cadmium chloride in a dose of 0.04 mg/kg of body weight of an animal for 30 days in animals suppressed protein synthesize function of the liver, which manifests itself by lowering the total protein of blood. It reached the lowest level at the 20th day of the experiment, where, accordingly, it fluctuated within the limits of 61.9 ± 1.14 g/l. Reducing the level of total protein in the blood of the bulls of the experimental group under cadmium loading was due to lowering the level of albumin. At day 20 of the experiment, the level of albumin in the blood of animals in the experimental group decreased by 16.5%. On the background of general hypoproteinemia there is a significant imbalance between albumins and globulins in serum of diseased animals. It was established that the level of globulins increased in the blood of Bulls, which were under cadmium load. Increasing the level of globulins in blood serum of bulls reflects the intensity of inflammatory processes in their body for cadmium loading.

scholarly journals Hematological parameters and content of lipids in tissues of the organism of rabbits according to the silicon connection

2020 ◽  
Vol 10 (1) ◽  
pp. 30-36 ◽  
Author(s):  
Y. Lesyk ◽  
A. Ivanytska ◽  
I. Kovalchuk ◽  
S. Monastyrska ◽  
N. Hoivanovych ◽  
...  
Keyword(s):  
Body Weight ◽  
Liver Tissue ◽  
Hematological Parameters ◽  
Total Lipid Content ◽  
Sodium Metasilicate ◽  
Control Group ◽  
Trophic Chain ◽  
Plastic Components ◽  
The Individual ◽  
Experimental Group

The article presents the results of the study for the influence of the rabbits feeding with various amounts of citric acid (25, 50 and 75 μg Si kg-1 of body weight, I-III experimental groups) from 52 to 110 days of life of the rabbits, obtained by nanotechnology method and sodium metasilicate (2.5 and 5.0 mg Si kg-1 of body weight, IV–V experimental groups) on hematological parameters and total lipid content and their fractional composition in the blood and liver tissue. It was established that the number of erythrocytes in the blood of rabbits in II and III experimental groups was higher by 18.4 and 20.7% (P0.05) at 31 days of study compared with control. At day 58 of the experiment, the total number of red blood cells in animals of the 1st, 2nd, and 3rd experimental groups was respectively higher by 14.9, 19.1, and 17.6% (P=0.05) than in the control. According to white blood indexes, the differences from control were found during the feeding of supplements with a significantly higher change of 30.9% (P=0.05) in 31 days in the blood of animals in the third experimental group. It was found that the feeding of silicic acid compounds did not significantly change the total lipids and phospholipids content, but led to the redistribution of their classes in the investigated tissues. Under the action of citrate silicon in the amount of 50 and 75 μg Si kg-1 of body weight, there was a decrease in the content of triacylglycerols in the blood plasma by 35 and 52% (P=0.05–0.01), respectively, compared with control. Investigation of the fractional lipids composition in the liver tissue showed a lower content of triacylglycerols and esterified cholesterol in animals of the II and III experimental groups compared with the control group. Consequently, the results of blood analyses and the fractional lipids composition in the individual tissues of the rabbit body indicate positive changes contributing to metabolic accumulation of energy and plastic components in the trophic chain and confirm the feasibility of adding citrate silicon in the rabbit diet, taking into account its physiologically substantiated amount.

scholarly journals Effect of silymarin supplementation on some productive and hematological parameters in meat type male Japanese quails

2019 ◽  
pp. 984
Author(s):  
Hristo Lukanov, Ivelina Pavlova ◽  
Veselin Ivanov, Todor Slavov, Yoana Petrova, Nadya Bozakova
Keyword(s):  
Body Weight ◽  
Growth Performance ◽  
Biochemical Parameters ◽  
Hematological Parameters ◽  
Control Group ◽  
Japanese Quails ◽  
Hematological And Biochemical Parameters ◽  
Experimental Group ◽  
Meat Type ◽  
Main Growth

A total of 90 14-day-old meat type male Japanese quails were included in the experiment and equally divided into 3 groups: control group (CG) without treatment, experimental group 1 (EG 0.5%), supplemented with silymarin 0.5% and experimental group 2 (EG 1%), supplemented with silymarin 1%. The aim of the current study was to establish the effect of supplementation with different doses of silymarin extract on the growth performance and some hematological parameters in male Japanese quails. Main growth performance (body weight, feed consumption and weight gain) were examined and FCR was calculated. Some hematological (WBC, RBC, HGB and HTC) and biochemical (triglycerides, AST and ALT) parameters were determined. The highest average body weight was observed in EG 0.5% group at 35-day-old age and the lowest in EG 1%, 239.61±2.96 g and 231.74±2.96 g respectively. The highest values of the weight gain were calculated in EG 0.5% group, 67.02±2.03 g during the first week of fattening and the lowest was observed in EG 1% group at the fifth week after hatching, 23.30±2.03 g respectively. The lowest values of FCR were observed during the first week of the trial, 2.42±0.08 kg/kg to 2.61±0.13 kg/kg in EG 1% and the control group respectively. The supplementation of 0.5% and 1% silymarin did not significantly change the studied hematological and biochemical parameters. A tendency of higher values of triglycerides and lower values of AST and ALT was observed in the groups, supplemented with silymarin compared to the controls. From the obtained results of the present study we can conclude that the silymarin supplementation at higher doses (0.5% and 1%) did not have effect on the main growth performance and some hematological and biochemical parameters of male Japanese quails.

scholarly journals Influence of sulfur complex on hematological indicators of the rabits

2018 ◽  
Vol 20 (92) ◽  
pp. 203-208
Author(s):  
A. Z. Dychok-Niedzielska ◽  
Y. V. Lesyk
Keyword(s):  
Body Weight ◽  
Sodium Sulfate ◽  
Hematological Parameters ◽  
Experimental Period ◽  
The Body ◽  
Control Group ◽  
Free Access ◽  
Group A ◽  
Hematological Indicators ◽  
Experimental Group

The article presents results on the influence of different amounts of sulfur citrate, manufactured using nanotechnology and sodium sulfate in rabbit diet from 60 to 118 days of age on the hematological parameters of their organism. Studies have been conducted on 30 rabbits of the Hyla hybrid divided into six groups (control and five experimental), 6 animals in each. Animals were kept in regulated microclimate and illumination in mesh cages of 50×120×30 cm. Controlled rabbits fed without restriction a balanced granulated feed with free access to water. The young of the first (E-II), the second (E-II), the third (E-III) and the fourth (E-IV) experimental groups feed the diet of the control group and, during the day, dispensed sulfur citrate from the calculation of 2; 4; 8 and 12 mg S/kg body weight. Rabbits (E-V) of the experimental group fed the diet of the control group and set water with sodium sulfate (Na2SO4) in the amount of 40 mg S/kg body weight. In the preparatory period – 60 days and in the experimental period – at 91 and 118 days of life (31 and 58 days of delivery of supplements), blood samples were collected from the regional anterior vein of rabbits for hematological studies performed using an automatic hematologic analyzer (Orphee Mythic-18, Switzerland). Researches have shown that the administration of citrate sulfur in the amount of 8 mg S/kg of body weight was marked by a greater number of red blood cells and leukocytes, respectively, by 13.4 and 23.3% (P < 0.05) and with a higher level of HCT at 16.2% (P < 0.05), MCH, RDV and MCHC, respectively, 11.1; 14.5 and 2.6% (P < 0.05) on day 58 of the experiment compared with the control group. In the blood of animals in the 2nd experimental group, a higher concentration of hemoglobin (Р < 0.05) was observed at 31 days and a higher HCT (Р < 0.05) level was 58 days compared to control. Thus, the results of the study of the hematological parameters of the body of rabbits indicate their positive changes in the actions of the physiologically substantiated amount of organic sulfur, which contributed to the activation of metabolic processes.

scholarly journals The influence of different amounts of zinc citrate on blood biochemical indices and productivity of rabbit organism

2019 ◽  
Vol 21 (96) ◽  
pp. 65-70
Author(s):  
Ya. V. Lesyk ◽  
M. M. Khomyn ◽  
I. V. Luchka ◽  
N. O. Bosanevich
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Total Protein ◽  
Body Weight Gain ◽  
Cholesterol Content ◽  
Daily Weight Gain ◽  
Control Group ◽  
Mineral Supplement ◽  
Daily Growth ◽  
Experimental Group

Deficiency of micro- and macronutrients in the organism of young rabbits causes disorders of metabolism and decreased productivity. Inclusion of essential micronutrients made by nanotechnology to the rabbit diet can eliminate this problem. Therefore, the purpose of our research was to investigate the influence of different amounts of zinc citrate in combination with cobalt and chromium citrates on the biochemical processes in the organism and the productivity of rabbits from 62 to 86 days of age. Researches were performed on rabbits 40 days of age, weighing 1.2–1.4 kg. The animals of the experimental groups were fed with fodder ration of the control group and during the day were fed with cobalt citrate in the amount of 40 μg Co/kg of body weight, chromium citrate – 40 mcg Cr/kg of body weight and zinc citrate, calculated respectively in I, II and III of experimental groups 0.25; 0.50 and 0.75 mg Zn/kg of body weight. In the preparatory period – on the 10th day and in the experimental on the 12th, 24th and 36th days of drinking the supplements in 4 animals from the group blood samples were taken for biochemical researches. Body weight gain was also determined by weighing. It was found that in the blood of animals of the first experimental group on the 12th day of drinking mineral additives increased the cholesterol content on 28.8%, on 24th day – decrease by 39.1% and increase – creatinine by 11.6%, and on 36th day – increase in blood of total protein on 12.3%, increase of alkaline phosphatase activity by 23.0%, creatinine content by 15.5% and average daily growth by 9.4%. A similar additive containing zinc citrate of 0.50 mg Zn/kg of body weight in the blood of rabbits of the second experimental group increased the activity of ACAT by 12 and 24 days, respectively, by 37.3 and 22.1%, respectively, and reduced their cholesterol content by 33.9 and 63.1% compared to the control. Whereas in the same group the growth of ALT activity was noted by 23.7%, and the average daily increase was higher than the control indicator by 7.9% 36 days of the research in comparison with the control group. The high content of zinc citrate in the mineral supplement (0.75 mg Zn/kg) in the blood of rabbits of the third experimental group contributed to the increase of the total protein concentration in all periods of the research, AST activity increased by 26.1% on the 24th day, AAT by 34.9% and the content of triacylglycerols and cholesterol was decreased, while on the 36th day the AAT activity increased by 20.3%, under these conditions, the average daily weight gain of rabbits was the highest and amounted to 38.4 g, which was 12.9% higher than the control. Therefore, the additive in the content of citrates of Co and Cr in the amount of 40 μg/kg of body weight and Zn citrate in the amount of 0.75 mg Zn/kg of body weight contributed to the improvement of metabolic processes and increase of growth indices, which may indicate the dose-dependent influence of the additives used in the rabbit young body.

scholarly journals The effect of cadmium loading on protein synthesis function and functional state of laying hens’ liver

2019 ◽  
Vol 9 (3) ◽  
pp. 221-226
Author(s):  
B. Gutyj ◽  
A. Ostapiuk ◽  
N. Kachmar ◽  
O. Stadnytska ◽  
O. Sobolev ◽  
...  
Keyword(s):  
Body Weight ◽  
Protein Synthesis ◽  
Functional State ◽  
Total Protein ◽  
Laying Hens ◽  
Normal Diet ◽  
The Body ◽  
Control Group ◽  
Cadmium Sulfate ◽  
Experimental Group

In the article are considered issues related to the study of the effect of cadmium on the body of birds, in particular laying hens. The effect of cadmium sulfate at doses of 2.0 and 4.0 mg/kg body weight on protein synthesis function and functional state of the liver were investigated of cross-laying Hysex white hens, of 78 weeks old. Three groups of chickens were formed: two experimental and one control groups. The laying hens of the experimental groups were subjected to a cadmium load. Laying chickens of the first experimental group were given cadmium sulfate at a dose of 2.0 mg/kg body weight. Laying chickens of the second experimental group were given cadmium sulfate at a dose of 4.0 mg/kg body weight. Laying chickens in the control group were in the normal diet without cadmium. Increased activity of aminotransferases, in particular alanine and aspartate aminotransferases in their serum of hens, was observed during cadmium binge drinking in doses of 2.0 and 4.0 mg/kg body weight, respectively. These changes indicate a violation of the functional state of the liver of laying hens under conditions of cadmium load. In the study of protein synthesis of the liver of laying hens under conditions of cadmium loading, it was found that cadmium sulfate in the above doses contributed to a significant decrease in the level of total protein by 14, 21 and 30 days of the experiment. The reduction of total protein in the blood of laying hens was due to a decrease in the level of albumin, which in the second experimental group, respectively, decreased to 28.16 ± 0.75%, whereas in the first – 29.62 ± 0.98%. In the study of the level of globulins, it is possible to increase this indicator in both experimental groups of poultry for 21 days. Drinking with water cadmium sulfate at a dose of 4.0 mg/kg body weight was associated with a more likely decrease in total protein and albumin than drinking cadmium sulfate at a lower dose.

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