Deformational plagiocephaly at birth: an observational study on the role of assisted reproductive technologies

2013 ◽  
Vol 27 (3) ◽  
pp. 270-274 ◽  
Author(s):  
Laura Pogliani ◽  
Chiara Cerini ◽  
Teresa Vivaldo ◽  
Piergiorgio Duca ◽  
Gian Vincenzo Zuccotti
Keyword(s):  
Observational Study ◽  
Assisted Reproductive Technologies ◽  
Reproductive Technologies ◽  
Deformational Plagiocephaly

scholarly journals Pannexins and Connexins: Their Relevance for Oocyte Developmental Competence

2021 ◽  
Vol 22 (11) ◽  
pp. 5918
Author(s):  
Paweł Kordowitzki ◽  
Gabriela Sokołowska ◽  
Marta Wasielak-Politowska ◽  
Agnieszka Skowronska ◽  
Mariusz T. Skowronski
Keyword(s):  
Assisted Reproductive Technologies ◽  
Mammalian Species ◽  
Atp Release ◽  
Reproductive Technologies ◽  
High Energy ◽  
Developmental Competence ◽  
Physiological Processes ◽  
Protein Group ◽  
Multicellular Organisms

The oocyte is the major determinant of embryo developmental competence in all mammalian species. Although fundamental advances have been generated in the field of reproductive medicine and assisted reproductive technologies in the past three decades, researchers and clinicians are still trying to elucidate molecular factors and pathways, which could be pivotal for the oocyte’s developmental competence. The cell-to-cell and cell-to-matrix communications are crucial not only for oocytes but also for multicellular organisms in general. This latter mentioned communication is among others possibly due to the Connexin and Pannexin families of large-pore forming channels. Pannexins belong to a protein group of ATP-release channels, therefore of high importance for the oocyte due to its requirements of high energy supply. An increasing body of studies on Pannexins provided evidence that these channels not only play a role during physiological processes of an oocyte but also during pathological circumstances which could lead to the development of diseases or infertility. Connexins are proteins that form membrane channels and gap-junctions, and more precisely, these proteins enable the exchange of some ions and molecules, and therefore they do play a fundamental role in the communication between the oocyte and accompanying cells. Herein, the role of Pannexins and Connexins for the processes of oogenesis, folliculogenesis, oocyte maturation and fertilization will be discussed and, at the end of this review, Pannexin and Connexin related pathologies and their impact on the developmental competence of oocytes will be provided.

scholarly journals Follitropin Delta as a State-of-the-Art Incorporated Companion for Assisted Reproductive Procedures: A Two Year Observational Study

Medicina ◽  
2021 ◽  
Vol 57 (4) ◽  
pp. 379
Author(s):  
Bogdan Doroftei ◽  
Ovidiu-Dumitru Ilie ◽  
Ana-Maria Dabuleanu ◽  
Roxana Diaconu ◽  
Radu Maftei ◽  
...  
Keyword(s):  
Observational Study ◽  
Ovarian Hyperstimulation Syndrome ◽  
Twin Pregnancy ◽  
Assisted Reproductive Technologies ◽  
State Of The Art ◽  
Follicle Stimulating Hormone ◽  
Exact Result ◽  
Reproductive Technologies ◽  
The Other ◽  
Ovarian Hyperstimulation

Background and objectives: The latest reports suggest that follitropin delta is a highly efficient recombinant human follicle-stimulating hormone (r-hFSH) that became a part of the current assisted reproductive technologies (ARTs). Therefore, the present study aims to assess a series of parameters (follicles, oocytes, and embryos) and further by the outcomes in women following the administration of follitropin delta. Materials and methods: This observational study included 205 women. They were aged between 21 and 43 years (mean 33.45) and an anti-Müllerian hormone (AMH) level ranging from 0.11 to 16.00 ng/dL (mean 2.89). Results: In accordance with the established methodology and following the centralization of data, a total of fifty-eight pregnancies (28.29%) were achieved; forty-five (36.88%) were achieved in women under 35 years and thirteen (15.66%) in women above 35 years. These figures are positively correlated with women’s age considering that the number of follicles >18 mm, oocytes fertilized and embryo(s) varies among groups. Regarding the interest parameters, we noted n = 1719 follicles > 18 mm, n = 1279 retrieved oocytes, and n = 677 embryos at day 3. On the other hand, the following figures have been registered in women above 35 years: 814–follicles > 18 mm, 612 oocytes retrieved and 301 embryos at day 3. During this study, we registered only three cases of abortions (n = 1–0.81% in women under 35 years and n = 2–2.40% in women above 35 years). Nine pregnancies (7.37%) were stopped from evolution in females under 35 years, and twelve pregnancies (n = 8–6.55% in women under 35 years, while n = 4 in women above 35 years) were unsuccessful. A twin pregnancy has been confirmed (1.20%) in women above 35 years, six ongoing pregnancies (4.91%) in those under 35 years, and two in both groups (one per group–n = 1–0.81%, and 1.20%–n = 1) in which we did not know the exact result were registered at the end of the established studied interval. However, there were also situations in which the treatment cause an over-reactivity or had no effect; n = 2 were non-responders, and n = 1 exhibited moderate ovarian hyperstimulation syndrome (OHSS). Conclusions: Based on our results, we strongly encourage the use of this recombinant gonadotropin on a much larger scale.

The role of maternal age in the assisted reproductive technologies

1999 ◽  
Vol 7 (1) ◽  
pp. 41-60 ◽  
Author(s):  
Mark A Damario ◽  
Owen K Davis ◽  
Zev Rosenwaks
Keyword(s):  
Older Women ◽  
Assisted Reproductive Technologies ◽  
Clinical Importance ◽  
Ovarian Response ◽  
Reproductive Technologies ◽  
Abortion Rate ◽  
Western World ◽  
Delayed Childbearing ◽  
Art Outcome

Age is perhaps the most important single variable influencing outcome in the assisted reproductive technologies (ART). The effect of advancing age on clinical ART outcome is manifested not only in the pattern of ovarian response to stimulation regimens, but also in reduced implantation efficiency and an increased spontaneous abortion rate. The clinical importance of these factors is compounded by the fact that increasing numbers of older women are presenting for ART treatment. Delayed childbearing is becoming increasingly common in the western world. The availability of methods of birth control, educational and career priorities for women, and the increased rates of divorce and remarriage are some of the factors contributing to this phenomenon.

The role of ALK5 in the profile of early reproductive losses in the use of assisted reproductive technologies

2021 ◽  
pp. 70-76
Author(s):  
Abuduwaili Ruziguli ◽  
Nikolai Nikolaevich Rukhliada ◽  
Anna Nikolaevna Taits ◽  
Tatyana Ivanovna Prohorovich ◽  
Tatyana Aleksandrovna Libova
Keyword(s):  
Natural Killer Cells ◽  
Natural Killer ◽  
Embryo Transfer ◽  
Spontaneous Abortion ◽  
Assisted Reproductive Technologies ◽  
Immunohistochemical Study ◽  
Reproductive Technologies ◽  
Decidual Tissue ◽  
Reproductive Losses

This article is devoted to the assessment of the role of ALK5 in the profile of early reproductive losses in the use of assisted reproductive technologies, in particular, by using immunohistochemical study in the group of patients with early spontaneous abortion after the procedure of embryo transfer, a lower level of ALK5 expression in the decidual tissue was revealed (in comparison with control), which may be related to the occurrence of early reproductive losses caused by the imbalance in Th1 / Th2 and its effect on the increase in the concentration of natural killer cells.

The role of diagnostic hysteroscopy and endometrial biopsy in assisted reproductive technologies

1998 ◽  
Vol 70 (2) ◽  
pp. 378-380 ◽  
Author(s):  
Giovanni B La Sala ◽  
Rossella Montanari ◽  
Luisella Dessanti ◽  
Corrado Cigarini ◽  
Fabrizio Sartori
Keyword(s):  
Assisted Reproductive Technologies ◽  
Reproductive Technologies ◽  
Endometrial Biopsy ◽  
Diagnostic Hysteroscopy

scholarly journals Microbiota and Human Reproduction: The Case of Female Infertility

2020 ◽  
Vol 9 (2) ◽  
pp. 12 ◽  
Author(s):  
Rossella Tomaiuolo ◽  
Iolanda Veneruso ◽  
Federica Cariati ◽  
Valeria D’Argenio
Keyword(s):  
Reproductive Tract ◽  
Assisted Reproductive Technologies ◽  
Embryo Implantation ◽  
Reproductive Technologies ◽  
Human Reproduction ◽  
Microbial Dysbiosis ◽  
Technical Issues ◽  
Almost All ◽  
Generation Sequencing

During the last decade, the availability of next-generation sequencing-based approaches has revealed the presence of microbial communities in almost all the human body, including the reproductive tract. As for other body sites, this resident microbiota has been involved in the maintenance of a healthy status. As a consequence, alterations due to internal or external factors may lead to microbial dysbiosis and to the development of pathologies. Female reproductive microbiota has also been suggested to affect infertility, and it may play a key role in the success of assisted reproductive technologies, such as embryo implantation and pregnancy care. While the vaginal microbiota is well described, the uterine microbiota is underexplored. This could be due to technical issues, as the uterus is a low biomass environment. Here, we review the state of the art regarding the role of the female reproductive system microbiota in women’s health and human reproduction, highlighting its contribution to infertility.

The role of the laboratory in the handling of epididymal sperm for assisted reproductive technologies

1992 ◽  
Vol 57 (5) ◽  
pp. 1103-1106 ◽  
Author(s):  
Teri Ord ◽  
Ellen Marello ◽  
Pasquale Patrizio ◽  
Jose P. Balmaceda ◽  
Sherman J. Silber ◽  
...  
Keyword(s):  
Assisted Reproductive Technologies ◽  
Reproductive Technologies ◽  
Epididymal Sperm

scholarly journals Assisted reproductive technologies in Russia: medical breakthroughs and social problems

2020 ◽  
Vol 4 (4) ◽  
pp. 5-18
Author(s):  
Nina E. Rusanova
Keyword(s):  
Public Perception ◽  
Assisted Reproductive Technologies ◽  
Professional Associations ◽  
Reproductive Technologies ◽  
Low Fertility ◽  
Reproductive Disorders ◽  
Hospital Statistics ◽  
Qualitative Characteristics ◽  
Demographic Policy

The paper considers the role of assisted reproductive technologies in changing the qualitative and quantitative characteristics of Russian fertility. The author analyzes the quantitative and qualitative characteristics of ART in Russia in 1986-2020, their public perception and current problems based on the data of national ART registers, reviews of international professional associations of reproductive specialists, secondary sociological information and hospital statistics. The general trend is the expansion of the geography of reproductive centers and the diversification of services, but the growing demand for ART as methods of alternative conception in the absence of reproductive disorders intensifies public debate around them, especially in the context of religion and children’s health. Nevertheless, in conditions of low fertility, the state considers ART as instruments of a pronatal demographic policy and finances them even against the backdrop of the coronavirus pandemic.

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