scholarly journals Possibilities of life quality correction of patients with chronic pancreatitis in postoperative hypothyroidis

Author(s):  
E. V. Chernyadeva ◽  
S. N. Styazhkina ◽  
T. E. Chernyshova ◽  
M. K. Ivanova ◽  
A. A. Zhuikova

Aim: to study the quality of life and the emotional state of patients with chronic pancreatitis on the background of postoperative hypothyroidism and the possibility of effective rehabilitation.Materials and methods. 270 patients with chronic pancreatitis were examined, among which 40 patients with primary postoperative hypothyroidism, who made up group 1, group 2 included 30 patients without thyroid pathology. Patients underwent a blood test according to the main biochemical parameters, hormonal blood count, ultrasound of the thyroid gland, hepatobiliary and duodenal zone. The study of quality of life and psychoemotional state by tests.Results In patients with chronic pacreatitis in combination with postoperative hypothyroidism among diseases of the hepatoduodenal zone, chronic non-calculous cholecystitis and non-alcoholic fatty liver disease were identified that are clinically characterized by abdominal pain syndrome according to the GSRS questionnaire. Patients revealed mild depressive state, high levels of personal and situational anxiety. The quality of life of patients was reduced both in physical and in psychological components, due to indicators of role-playing physical and emotional functioning. Against the background of treatment with a combination of succinate-containing drugs, the severity of depression, situational and personal anxiety decreased, and role functioning due to physical and emotional state, social functioning increased.Conclusions: The use of combination therapy with sodium levothyroxine and ethylmethylhydroxypyridine succinate in patients with comorbid pathology during postoperative hypothyroidism improves the clinical picture, psychoemotional balance and quality of life.

Author(s):  
Yu. V. Antonova ◽  
A. M. Iskandarov ◽  
I. B. Mizonova

Introduction.Coccygodynia is a multidisciplinary disease which is diffi cult to treat. It seriously limits the ability to work and signifi cantly affects the quality of life of patients. The study of somatic dysfunctions in patients with coccygodynia and the analysis of the results of osteopathic treatment of such patients makes it possible to justify the necessity of osteopathic correction of coccygodynia.Goal of the study— to determine the structure of the leading somatic dysfunctions in patients with coccygodynia and to study the effectiveness of osteopathic treatment of this pathology.Materials and methods.The study involved 44 patients from 25 to 65 years old, randomly divided into two groups. The main group of 24 people (20 women and 4 men) received osteopathic treatment, in accordance with the identifi ed leading somatic dysfunctions. Patients of the control group (16 women and 4 men) were treated locally with soft manual techniques (the treatment area was limited by the pelvic region). In order to assess the results of the treatment, we examined the intensity of the pain syndrome and the psycho-emotional state of patients. The severity of the pain syndrome was assessed in accordance with the visual analogue scale (VAS). The psycho-emotional state (with physical and mental components) was assessed with the help of the SF-36 quality of life questionnaire.Results.Somatic dysfunctions typical for patients with coccygodynia have been identifi ed. Osteopathic treatment has proven to be more effective in comparison with local manual therapy of coccygodynia both in early periods and in 3 months after the end of the treatment course.Conclusion.Osteopathic treatment of post-traumatic coccygodynia is effective, and can be recommended for treatment of such patients.


2021 ◽  
pp. 57-61
Author(s):  
E. V. Chernyadeva ◽  
A. E. Shklyaev

The aim. To study the quality of life and psychoemotional state of patients with non-alcoholic fatty liver disease against the background of primary hypothyroidism during the use of ethylmethylhydroxypyridine succinate.Materials and methods. 111 patients with non-alcoholic fatty liver were examined, among them 35 were without thyroid dysfunction, 55 with compensated primary hypothyroidism, 21 with decompensated hypothyroidism. The patients underwent general clinical, biochemical, enzyme-linked immunosorbent assays of blood, instrumental studies, testing according to psychological questionnaires.Results. With decompensation of hypothyroidism, a statistically significant increase in indicators of depression, situational and personal anxiety was revealed in comparison with patients without hypothyroidism. The examined patients showed an increase in the level of situational and personal anxiety. The presence of hypothyroidism in the examined patients significantly worsens these indicators, leading to an increase in the degree of anxiety, aggravated by decompensation of hypothyroidism. A positive dynamic was revealed in the correction of the psychoemotional status of patients in the observation group during the complex treatment with ethylmethylhydroxypyridine succinate: the severity of depression, situational and personal anxiety, manifestations of dyspeptic and reflux syndromes decreased.Conclusion. Hypothyroidism affects the quality of life and psycho-emotional state of patients with non-alcoholic fatty liver disease: it worsens the degree of depression, situational and personal anxiety. The addition of ethylmethylhydroxypyridine succinate to standard therapy with sodium levothyroxine in patients with non-alcoholic fatty liver disease in the setting of hypothyroidism improves the quality of life and psycho-emotional state.


Purpose. To analyze quality of life dynamics of patients with trophic venous ulcers of the lower limbs after the treatment with the use of photodynamic therapy. Materials and methods. Quality of life research was conducted in 57 patients with trophic ulcers of venous etiology. The first group included 30 patients who received standard treatment, the second group — 27 patients, in which standard treatment was combined with a course of photodynamic therapy. To assess the quality of life of the patients in both groups, a questionnaire was conducted using the EuroQol-5D-5L survey system and the visual analogue scale EQ-VAS. The quality of life assessment was carried out at the beginning of treatment, 10 days and 6 weeks after starting treatment. Results. The results indicate a significant improvement in the quality of life in both groups, but the degree of improvement in this indicator in group 2 was 20.7 % higher.An analysis of the dynamics of improvement in quality of life showed an increase in the mean of the indicator 10 days after the beginning of treatment in patients in the first group of 26.7 %, the second group by 43 %, and in 6 weeks, its increase was achieved in patients in the first group by 32.7 %, in the second group — by 53.4 %. Conclusions. The use of photodynamic therapy in the treatment of venous trophic ulcers significantly affects the quality of life, which is manifested in the anti-inflammatory effect and reduction of pain syndrome in the shorter term (by 76.2 %), compared with patients in the first group.


2021 ◽  
Vol 63 (1) ◽  
pp. 33-37
Author(s):  
Liliya S. Babinets ◽  
Halyna M. Sasyk ◽  
Iryna M. Halabitska ◽  
Victoria R. Mykuliak

Introduction: An important place in the formation of the rehabilitation program is occupied by non-drug methods, such as physiotherapy, reflexology, spa treatment, the use of which improves the effectiveness of correction of complications, reduces drug load, allows to achieve sustainable compensation for diabetes and chronic pancreatitis (CP), and also improves life quality suffering from such comorbidity. Aim: to investigate the effectiveness of the use of acupuncture in the complex rehabilitation of patients with type 2 diabetes in combination with chronic pancreatitis based on an assessment of the quality of life (QOL) and clinical parameters. Material and Methods: 60 patients with type 2 diabetes in combination with CP were examined and divided into 2 groups. The average age of the patients was (52.86±0.83) years. Control group – 15 healthy persons. To evaluate QOL, a questionnaire was interviewed using the SF-36 questionnaire in treatment dynamics. All patients with type 2 diabetes in combination with CP received adequate conventional therapy. In addition to the treatment, the patients of group II received the acupuncture course according to the methodology, which was formed on the basis of the experience of the Kyiv School of reflexology (EL Macheret et al.) and the Beijing School (Kong Lin). Results: Faecal α-elastase levels increased by 14.9% in group 1, by 25.6% in group 2, blood glucose decreased by 9.2% in group 1 and by 19.5% in group 2, HbA1c level – by 4.9% in Group 1 and by 12.2% in Group 2, changes in coprogram parameters in points – by 24.5% in Group 1 and by 55.2% in Group 2. According to the SF-36 scales, there was a positive dynamics of quality of life in patients of both groups. In group 2, there was a more significant positive trend in the total indicator of mental status (increased by 17.75% (p <0.001) versus 8.71% (p <0.005) in the group 1, respectively) and physical status (increased by 2.59% ( p <0.05) versus 7.19% (p <0.05)). Conclusions: Improved exocrine and endocrine functions of the pancreas, as well as improved quality of life in patients treated with a course of acupuncture increase the efficiency of complex rehabilitation of patients with type 2 diabetes in combination with CP was found.


2012 ◽  
Vol 93 (1) ◽  
pp. 34-38
Author(s):  
A A Karpachev ◽  
I P Parfenov ◽  
A Yu Khlynin ◽  
A L Yarosh ◽  
A V Soloshenko ◽  
...  

Aim. To conduct a comparative evaluation of the effectiveness of surgical treatment of chronic pancreatitis and define the quality of life of patients depending on the methods of surgical treatment. Methods. The study included 81 of the 165 patients with chronic pancreatitis, who underwent the following operations: endoscopic transmural interventions through the wall of the stomach and duodenum, endoscopic transpapillary surgery, percutaneous interventions for sanitation and drainage of the cystic cavity, laparotomic operations of internal drainage, resection interventions. The quality of life of patients was assessed using the general health questionnaire SF-36. Results. The lowest level of life quality was established in the group of patients after endoscopic transpapillary interventions. Statistically significant differences in the level of physical and psychological health were established when comparing patients after endoscopic transpapillary interventions and after endoscopic transmural surgical interventions, which were carried out through the wall of the stomach and duodenum; differences only in the level of physical health were noted when comparing with the group of resection interventions. Conclusion. The quality of life of patients with chronic pancreatitis depends on the type of surgical intervention, age and sex of the patients.


2021 ◽  
Vol 100 (6) ◽  
pp. 560-567
Author(s):  
F. I. Ingel ◽  
O. V. Budarina ◽  
L. V. Akhaltseva

Introduction. It is known that an extraneous odour can cause an adverse emotional reaction of a person and, as a result, reduce the quality of life, which is most likely the reason for a large number of complaints of air pollution from the population. The converse statement about the influence of a person’s emotional state on his/her perception of a smell can also be true. An assessment of the relationship between odour characteristics and emotional state of a person can be investigated in a laboratory olfactory-odorimetric study with the participation of specially trained investigators. The aim of this study was to analyze in laboratory conditions the impact of odour with high annoyance potential on human feeling, activity, and mood. Materials and methods. Ten 26-71-years healthy investigators of both genders, who have been psychologically tested with a block of standard psychological questionnaires to evaluate emotional stress expression and quality of life, took part in 2 series of odorimetric studies on the ECOMA T08 olfactometer. During this study, they assessed the odour intensity and annoying effect of multicomponent odorant with isopropyl mercaptan, ethyl mercaptan, and 2-butanethiol largest contribution (unpleasant odour). The influence of the odour on investigators’ feeling, activity, and mood before, during, and after odorimetry was determined using a FAM (feeling, activity, and mood) test card. The study results showed the perception of unpleasant smell to be connected with investigators’ age, emotional state at the time of odorimetry, and some indices of the life quality. It is established that the perception of the smell in its tangible concentrations can lead to increased activity and improved mood. At the same time, exposure to the odour in higher concentrations, in most cases, was associated with decreased activity and mood, as well as - for some investigators - with decrease of feelings regardless of age. The given work results comparison with data obtained in the only similar study of odour emissions of chewing gum production carried out with a common methodic approach and on the same equipment, demonstrated a qualitative similarity in the perception of an extraneous odour of different hedonic tone: a connection with age, background emotional state, and quality of life indicators. Moreover, it was revealed odours of different hedonic tones to influenced in the same way on investigators’ activity and mood indices. Conclusion. Although the obtained results do not allow us to unambiguously conclude which odour strength (concentration of odorous substances) is an unacceptable value for all investigators, the similar research implementation is necessary to study the odour impact on the human adaptation systems. In addition, the data obtained allow us to conclude that all complaints of the presence of an extraneous odour of any character and hedonic tone, are most often justified, deserve careful attention and a quick response from the sanitary services.


2019 ◽  
Vol 23 (2) ◽  
pp. 238-242
Author(s):  
G. S. Moskovko ◽  
Ya. V. Nikitchuk ◽  
A. V. Kostiuchenko ◽  
N. V. Tytarenko ◽  
A. I. Semenenko

The study included 258 (96 males, 162 females) of patients in the age of 52.2±14.16 years with pain in the lumbar-sacral part of spine due to degenerative-dystrophic changes. Among them: 30 patients received medication treatment (group 1, control), 114 transforaminal epidural block (group 2) and 114 — caudal epidural blockades (group 3, n = 114). Period of observation was 6 months. The assessment of the intensity of the pain was performed on the visual analog scale (VAS), the quality of life — on the Oswestry Disability Index (ODI) and the Short Form Health Survey-36 (SF-36). Caudal and transforaminal epidural blockades could effectively reduce the intensity of pain (p<0.05). 98.2% of patients reported regression of pain immediately after caudal epidural blockades, but the positive result remained during 6 months after procedure in only 59.6% of patients. Transforaminal epidural block contributed to a significant decrease the intensity of pain according to the VAS in the whole group and different monitoring periods in 76.4–91.2% of patients. Both methods are effective for treatment of the lumbar pain syndrome and are associated with a positive dynamic of patient quality of life. However, caudal epidural blockades are more effective in the short term.


2016 ◽  
Vol 95 (1) ◽  
pp. 12 ◽  
Author(s):  
Lucas Romagnolli ◽  
Vivian Romanholi Coria ◽  
Sérgio Henrique Navarro Júnior ◽  
João Eduardo Torrecillas Sartori ◽  
Alethea De Souza Romanelli ◽  
...  

Fibromyalgia is a chronic musculoskeletal pain syndrome characterized by the presence of painful points on digito-palpation in anatomical specific areas, called trigger points, followed by psychological disorders like sleeping problems and alexithymia. Alexithymia is a dimension defined as the absence of words for emotions. The patient does not know how to process their own emotions and fail to externalize what feels. The investigation of possible relationship between Fibromyalgia and Alexithymia can increase knowledge about the clinical features resulting from both diseases, especially because alexithymia is poorly explored and has a significant impact in patient’s life quality. Objectives: To execute a literature review searching for a clinical association between Alexithymia and Fibromyalgia (FM), highlighting psychiatric and psychological aspects. Methods: Folowing PRISMA statement the research used Scielo, Pubmed, PsychLit and ISIweb of knowledge data base between 2009 and 2014 with the key-words: “alexithymia”, “fibromyalgia”, “psychosomatics”, “chronical pain”, “psycotherapy”, “psychoanalysis”. Results: Nine studies were selected for analysis which used instruments like the Toronto Alexithymia Scale, the psychoanalysis and cognitive comportamental therapy showing that the patient with Alexithymia and FM has a worse pain interpretation, deals badly with it and suffer the consequences in their physical and mental health due to that. Conclusion: This study suggested the important impact that alexithymia has in patients with FM, since the psychiatric and psychological factors lead to a bigger decrease in life quality of people who have already worse aspects in that, which warn for the importance of this emotional state, since it is under-diagnosed. Due to the fact that there were a small number of reviewed articles, more research about the relation between FM and Alexithymia must be done.


2017 ◽  
Vol 5 (2_suppl2) ◽  
pp. 2325967117S0009
Author(s):  
Gülvin Canan ◽  
Derya Çelik

Purpose: Many knee pathologies negatively affects the quality of life of patients. The aim of this study was to determine the relationship between type of pathology, duration of rehabilitation and quality of life. Method: 154 (mean age, 34.74 ± 11.8 years, 73 women) patients with meniscectomy, anterior cruciate ligament reconstruction, and patellofemoral pain syndrome treated conservatively were included in the study. The mean follow-up was 14.5 (range, 8-20) months. The patients were divided into 3 groups; meniscectomy group (Group 1; 52 patients; mean age, 37.0 ± 8.9, 27 women), anterior cruciate ligament reconstruction group (Group 2; 47 patients; mean age, 28.6 ± 8.5 years, 11 women) and patellofemoral pain syndrome group (Group 3; 50 patients; mean age, 37.7 ± 13.6, 35 women). Short Form (SF-36) was used to assess the quality of life. One-way ANOVA was used for statistical analysis with the SPSS 20 software. p <0.05 was considered significant. Results: Group 2 was found significantly younger (p=0.001). The SF-36 subscales exept physical role and mental health were different among groups ( Table 1 ). When this difference was analysed, social, physical and mental health were found to be better in Group 2. [Table: see text] Conclusion: Quality of life and function of the patients appears to be significantly better in the anterior cruciate ligament group. Anterior cruciate ligament injury usually affects the younger population and they have higher motivation for treatment. In addition, we believe that patients takes longer rehabilitation program has better qality of life.


2017 ◽  
Vol 95 (8) ◽  
pp. 729-734
Author(s):  
Nadezhda A. Nikiforova ◽  
T. A. Karapetyan ◽  
N. V. Dorshakova

Objective: to estimate the quality of life (QOL) in the patients with duodenal ulcers residing in the North European part of Russia and treated by melatonin therapy in addition to standard anti-ulcer therapy using the GSRS questionnaire. Materials and methods: the study involved 80 patients with uncomplicated duodenal ulcer in the acute stage randomized into 2 groups: group I (n= 40) given three-component treatment (omeprazole, clarithromycin, amoxicillin) with the addition of melatonin and group 2 (control, n=40) given the same therapy but without melatonin. Taking into account the peculiarities of photoperiodicity in the study region, group 1 was subdivided into subgroups A and B and group 2 into subgroups C and D (A and C- received treatment from March to August; and B and D-from September to February). The quality of life was assessed based on the Russian-language version of GSRS before and on day 14 after onset of therapy. The clinical picture of the disease in groups 1 and 2 before treatment was dominated by abdominal (AU) and reflux (RS) syndromes. On 14 after onset of therapy, life quality improved in both groups but to a lesser degree in group 2 than in group 1 due to significantly more pronounced abdominal pain and reflux syndrome as well as worse results of evaluation from GSRS. In all subgroups, the number of GSRS points on the whole and for each scale of the questionnaire decreased on the 14th day of therapy . However, subgroup C showed a higher prevalence of abdominal pain and reflux syndrome than subgroup A as well as poorer GSRS-based estimates. Subgroup B differed in a similar way from subgroup D. Conclusion: anti-ulcer therapy in combination with melatonin is more effective than without it especially if started in a period of growing daylight duration and its maximum.


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