scholarly journals Status of Vitamin D among Patients Visiting a Tertiary Care Centre in Rupandehi, Nepal

2021 ◽  
Vol 9 (4) ◽  
pp. 256-260
Author(s):  
Tirtha Narayan Shah ◽  
Amar Kumar Sinha ◽  
Krishna Kumar Jha ◽  
Ram Jiban Prasad
Keyword(s):  
Vitamin D ◽  
Tertiary Care ◽  
Age Groups ◽  
Serum Vitamin ◽  
Hypovitaminosis D ◽  
Target Population ◽  
Tertiary Care Centre ◽  
Medical College ◽  
Serum Vitamin D ◽  
High Level

Serum vitamin D is one of the fat-soluble vitamin which has the role in maintenance of calcium and phosphorus levels  and ultimately proper bone health and various physiological processes.  Although many studies prevail hypovitaminosis D, we focused to find out the pattern of  elevated or decreased  serum vitamin D level as its deficiency and surplus have adverse effects to our health.. For this, a retrospective study was done from the records present in a hospital laboratory of Devdaha Medical College and Research Institute (DMCRI), Rupandehi, Nepal from January 2018 to December 2020 where 201 participants with 70.1% male and 29.9% female with different age groups were present. From total participants, 14.9% had deficient, 42.8% had insufficient, 35.3% had sufficient and 7%  had high level of serum vitamin D. Male had 2.9% deficient and 14,9% insufficient vitamin D whereas female had 11.9% deficient, 27.8% insufficient and 7.0% surplus vitamin D. The greater prevalence of hypovitaminosis D in the females than the males could be overcome by the necessary strategies in the form of further studies and judicious supplementation vitamin D in the target population by monitoring the level of serum vitamin D. Int. J. Appl. Sci. Biotechnol. Vol 9(4): 256-260.

scholarly journals Correlation between Asthma Severity and Serum Vitamin D Levels: Experience from a Tertiary Care Centre in North India

2018 ◽  
Vol 07 (03) ◽  
Author(s):  
Haider Guru ◽  
Sonaullah Shah ◽  
Roohi Rasool ◽  
Qurteeba Qadri ◽  
Faisal R Guru ◽  
...  
Keyword(s):  
Vitamin D ◽  
Tertiary Care ◽  
Serum Vitamin ◽  
Asthma Severity ◽  
North India ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Serum Vitamin D ◽  
Vitamin D Levels

scholarly journals Prevalence of Hypovitaminosis D in Patients Visiting a Tertiary Care Center in Chitwan, Nepal

2019 ◽  
Vol 15 (2) ◽  
pp. 84-92
Author(s):  
Kushal Bhattarai ◽  
Nilu Manandhar ◽  
Sarita Dhakal
Keyword(s):  
Vitamin D ◽  
Care Center ◽  
Tertiary Care ◽  
Large Body ◽  
Serum Vitamin ◽  
Hypovitaminosis D ◽  
Demographic Variables ◽  
High Rate ◽  
Care Hospital ◽  
Serum Vitamin D

Background: As documented by a large body of evidences, Hypovitaminosis D prevails both in the general and the hospitalized populations. We conducted this study to determine the prevalence of hypovitaminosis D amongst the patients visiting a tertiary care hospital and compare the rate gender-wise, across different categories of socio-demographic variables. Methods: It was a cross-sectional study (retrospective chart review) based on the hospital registry of patients at College of Medical Sciences and Teaching Hospital, Bharatpur, Chitwan, Nepal. From the registry, we retrieved the socio-demographic variables (age, gender, ethnicity and season) along with serum vitamin D (25-hydroxy-cholecalciferol) concentrations of the study subjects from January 2015 to August 2018, for our analysis. Hypovitaminosis D was defined as serum vitamin D <30 ng/mL (insufficiency: 20-30ng/mL and deficiency: <20 ng/mL). Results: The overall prevalence of hypovitaminosis D was 70.7% (insufficiency: 35.9% and deficiency: 34.8%), 72.4% (females), 64.2% (males), 76.3% (first age-quartile), 74.5% (miscellaneous ethnic group), and 73.9% (Spring). Females had higher prevalence rates of hypovitaminosis D (and lower median serum 25-hydroxy-cholecalciferol lev-els) as compared to males, in overall participants, and those under each category of age, ethnicity and season (except Winter). Conclusions: The greater prevalence of hypovitaminosis D in the females than the males in the face of high rate in the overall hospital-visiting clearly calls for necessary strategies in the form of further studies and judicious prescription of supplementary vitamin D in the target population.

scholarly journals Evaluation of vitamin D status in suspected cases of metabolic syndrome

2019 ◽  
Vol 7 (5) ◽  
pp. 1515
Author(s):  
Radhika Krishnaswamy ◽  
Shelomith K. Chawang ◽  
Priyadharshini Krishnaswamy
Keyword(s):  
Metabolic Syndrome ◽  
Vitamin D ◽  
Tertiary Care ◽  
Fasting Blood Glucose ◽  
Age Groups ◽  
Serum Vitamin ◽  
Care Hospital ◽  
Serum Vitamin D ◽  
Increased Risk ◽  
Vitamin D Levels

Background: Metabolic syndrome is associated with an increased risk of cardiovascular disease and type 2 diabetes mellitus. Vitamin D has been linked to glucose metabolism and insulin regulation. Hence, this study aims to evaluate the association between the serum level of vitamin D and metabolic syndrome. This may help generate additive strategies in the prevention and management of this syndrome. The objective of the study was to compare the levels of serum vitamin D in subjects with metabolic syndrome and subjects without metabolic syndrome.Methods: A prospective study with 80 subjects was conducted at a tertiary care hospital in Southern India. The sample comprised 40 subjects in the age group of (18-60 years) with metabolic syndrome as cases and 40 subjects without metabolic syndrome in the age groups of (18-60 years) as controls. The presence of any 3 of the following- fasting blood glucose (FBS ≥100mg/dl), triglycerides (TGL≥150mg/dl) and high-density lipoprotein cholesterol (HDL-C ≤40mg/dl-men, ≤50mg/dl-women) levels, blood pressure (≥130/85mmHg or drug treatment) and abdominal waist circumference (>94 cm (37 in) in men and >80 cm (31 in) in women) were used as criteria to screen for the presence (cases) or absence (controls) of metabolic syndrome. Serum vitamin D (25-hydroxy vitamin D) levels were compared between the two groups.Results: Mann Whitney U test was used to compare the vitamin D levels between the two groups. Significantly (p=0.05) lower vitamin D levels were seen in the cases compared to the controls.Conclusions: Metabolic syndrome is associated with significantly lower serum vitamin D levels. We suggest that further studies with a larger sample size be undertaken to confirm the same.

scholarly journals Study of vitamin D levels in exclusively breastfed term infants in a tertiary care centre

2017 ◽  
Vol 5 (1) ◽  
pp. 71
Author(s):  
Soumya M.
Keyword(s):  
Vitamin D ◽  
Tertiary Care ◽  
Child Survival ◽  
Serum Vitamin ◽  
Lower Amount ◽  
Contributing Factors ◽  
Tertiary Care Centre ◽  
Term Infants ◽  
Serum Vitamin D ◽  
Vitamin D Levels

Background: Exclusive breast-feeding is recommended up to 6 months of age with all its beneficial effects on child survival. Several studies have concluded that adequate intake of vitamin D cannot be met with human milk as the sole source of vitamin D. So this study was undertaken to study the serum vitamin D levels in exclusively breastfed babies and their mothers in a tertiary care hospital.Methods: It was a prospective observational study. A minimum of 100 healthy infants born at term (38-42 weeks) and weighed >2.5kgs at birth and who were exclusively breast fed from age group 3-6 months attending the hospitals attached to J J M M C were selected for study. Approval from the ethical committee of the institution was obtained.Results: In this study there were totally 43% of males and 57% of females. Among them 14 (14%) of the infants were vitamin D deficient and 19 (19%) infants were vitamin D insufficient. And in 100 mothers studied 25 (25%) mothers were vitamin D deficient and 24 (24%) mothers were insufficient of vitamin D. The mean vitamin D level in infants was 25.72 ng/ml (±11.31ng/ml) and in mothers’ it was 22.09ng/ml (±9.17ng/ml).Conclusions: Breastfeeding might be one the contributing factors if the infant is not adequately exposed to sunlight for endogenous synthesis of vitamin D and if the mother is deplete in vitamin D levels transferring lower amount of vitamin D to infant through breast milk. 

scholarly journals A Study on Vitamin D Levels in Patients Attended at OPD of A Tertiary Care Hospital of Chattogram

2020 ◽  
Vol 18 (2) ◽  
pp. 37-40
Author(s):  
Shaheda Ahmed ◽  
Md Jalal Uddin ◽  
AYM Masud Reza Khan
Keyword(s):  
Vitamin D ◽  
Tertiary Care ◽  
Serum Vitamin ◽  
Hypovitaminosis D ◽  
Whole Body ◽  
Care Hospital ◽  
Mineral Density ◽  
Female Ratio ◽  
Serum Vitamin D ◽  
Vitamin D Levels

Background: Vitamin D is a fat soluble vitamin, having important role in calcium and phosphorous metabolism. Many researches support the role of vitamin D against cancer, cardiovascular diseases, fractures and falls, cognitive disorders, Parkinsonism, auto-immune diseases, respiratory ailments and depression. Thus Vitamin D Deficiency (VDD) is an alarming public problem. Purpose of this study was to measure the frequency of hypovitaminosis D among different age and sex group of Chattogram, Bangladesh. Materials and methods: A cross sectional hospital based observational study was conducted over a period of six months from February 2018 to July 2018 at a leading diagnostic complex and hospital of Chattogram. A total of 243 patients were included in the study. Number of male and female respondents were 86 and 157 respectively. Age range was 15-85 years. Blood samples were collected aseptically after an oral informed consent. Serum vitamin D levels were estimated using standard laboratory technique (Chemiluminescent microparticle immunoassay method). Results: Among 243 respondents, male female ratio was 1:1.83, mean age was 47± 16.3 years, prevalence of hypovitaminosis was 82%, among male hypovitaminosis was found in 78% cases, whereas among female it was a bit higher with 84%. Sex difference was strongly significant with p value of < 0.01. Conclusion: The present study has limitation with estimation of only vitamin D, in absence of valuable indicators of bone health like serum calcium, bone mineral density and parathyroid hormone. Factors like, less outdoor activities, obesity or covering whole body (Abaiya or burkah) in case of Muslim women, which could be responsible for more hypovitaminosis in case of female was not noticed. But it was very much clear that 45-60 years age group was the most vulnerable with highest level of hypovitaminosis-D in both sexes. Chatt Maa Shi Hosp Med Coll J; Vol.18 (2); July 2019; Page 37-40

scholarly journals STUDY OF SERUM VITAMIN D LEVELS IN PREECLAMPTIC WOMEN BELOW 35 YEARS IN A TERTIARY CARE CENTRE IN SOUTHERN ASSAM, INDIA.

2017 ◽  
Vol 5 (8) ◽  
pp. 1186-1191
Author(s):  
Aparajeeta Bora ◽  
◽  
MauchumiSaikia Pathak ◽  
ArunPaul Choudhury ◽  
Biswadeep Choudhury ◽  
...  
Keyword(s):  
Vitamin D ◽  
Tertiary Care ◽  
Serum Vitamin ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Serum Vitamin D ◽  
Vitamin D Levels

scholarly journals Histopathological examination and evaluation of serum vitamin D levels in alopecia-is it necessary?

2020 ◽  
Vol 11 (e) ◽  
pp. e153.1-e153.3
Author(s):  
Romita Bachaspatimayum ◽  
N.A Bishurul Hafi ◽  
Bipin Thingujam
Keyword(s):  
Vitamin D ◽  
Skin Biopsy ◽  
Clinical Diagnosis ◽  
Histopathological Examination ◽  
Tertiary Care ◽  
Serum Vitamin ◽  
P Value ◽  
Tertiary Care Centre ◽  
Serum Vitamin D ◽  
Vitamin D Levels

Background: Alopecia or hair loss may be of several types depending upon various etiological factors. Clinical and histopathological lapses have been encountered. Vitamin D has been found to have a role in the etiopathogenesis of alopecia. With this background, the study was undertaken to corroborate the histopathological and the clinical diagnosis and to find out the association between vitamin D levels and alopecia. Material and Methods: All patients of alopecia, attending out-patient Department of Dermatology in a tertiary care centre who were willing to participate were included while those due to infective causes or with incomplete reports were excluded from the prospective study of two years (January 2015-December 2016). Histopathological examination of skin biopsy was done and corroborated with the clinical diagnosis along with measurement of serum vitamin D levels by electrochemiluminescense immunoassay (ECLIA). Data was analyzed by spss20v; Fischer’s Exact test was used and a p value of 0.05 was taken as significant. Results: Out of total 50 patients, 20 (male:female=1.5:1) patients had both HPE and serum vitamin D reports and their results were analyzed. HPE and clinical diagnosis matched in only 10 patients (50%) with a significant p-value (p=0.007; p<0.05). Sufficient levels (>/= 30 ng/ml ) of serum vitamin D were found in only three (15%) with p value >0.05 (0.421) which was not significant. Conclusion: H.P.E. finding was significantly variable compared to clinical diagnosis. Hence, we should opt for a confirmatory skin biopsy wherever feasible. Evaluation of vitamin D is suggested with studies on a larger scale.

Association of Vitamin D Deficiency in Newly Diagnosed Pulmonary Tuberculosis

2021 ◽  
Vol 15 (10) ◽  
pp. 2572-2573
Author(s):  
Khalil Ullah ◽  
Sajid Ur Rehman ◽  
Ramsha Nadeem ◽  
Muhammad Abubakar ◽  
Qasim Raza
Keyword(s):  
Vitamin D ◽  
Pulmonary Tuberculosis ◽  
Vitamin D Deficiency ◽  
Serum Vitamin ◽  
Sampling Technique ◽  
Hypovitaminosis D ◽  
Control Group ◽  
Sputum Smear ◽  
Study Group ◽  
Serum Vitamin D

Aim: Relationship between Vitamin D deficiency and pulmonary tuberculosis. Methodology: Study duration: November 2020 to April 2021 Sampling technique: A case-control study Setting: Hayatabad Medical Complex, Peshawar It included 30 adult newly identified sputum-quality pulmonary tuberculosis patients and 30 age and sex matched healthy cases as controls. All cases had undergone a thorough medical examination and repeated laboratory tests, including vitamin D, calcium, and sputum for AFB and X-ray chest. Results: Majority were males (88%). In the Study group, BMI decreased significantly i.e. 19.0 vs 23.5. Serum vitamin D concentrations were significantly lower in the tuberculosis group i.e. 17.9ng/dl than in the control group 24.8ng/dl. Mean of serum albumin in the control group was 3.9 ng/dl whereas 2.9 ng/dl in the study group. Conclusion: Hypovitaminosis D was associated with more severe medical symptoms, increased sputum smear positivity and large lesions on chest radiographs in patients with pulmonary tuberculosis. Keywords: Vitamin D, Pulmonary Tuberculosis, Sputum

scholarly journals High Prevalence of Hypovitaminosis D in Climacteric and Beyond in a Teaching Center from North Eastern India

2020 ◽  
Vol 5 (02) ◽  
Author(s):  
Dr Nalini Sharma ◽  
Dr Rituparna Das ◽  
Dr Alice Abraham Ruram ◽  
Dr Subrat Panda
Keyword(s):  
Vitamin D ◽  
Tertiary Care ◽  
Hypovitaminosis D ◽  
Eastern India ◽  
Tertiary Care Centre ◽  
The North ◽  
North Eastern ◽  
North Eastern India ◽  
Post Menopausal ◽  
North Eastern Part

Background: Data on the prevalence of hypovitaminosis D in peri and post menopausal tribal multiethnic Indians women living in the North Eastern part of the country are limited. Aim: To evaluate the vitamin D(VD) level in North Eastern multiethnic tribal perimenopausal and postmenopausal women Indian women. Material and Method: This prospective study was conducted at a tertiary care centre from 2018 to2019in North Eastern India Catering multiethnic tribal population. A total of498women above 40 years of age who attended gynae opd for various reasons were included in the study Women were advised to give 3 cc blood samples. The serum VD was estimated by Beckman Coulten Unicel DXI immunoassay system using the principle of chemiluminescence, Incidence of Vitamin D deficiency (VDD) and insufficiency (VDI) calculated. VDD was defined as 25(OH) D level in blood<20ng/ml and insufficiency of VD was defined as 25(OH) D levels <30ng/ml/. Result: In present study mean age was 46.78±6.914 years. 50.40%women were vitamin D deficient. 37.95% women were vitamin D insufficient. Mean parity was 3.94±9.23 and mean value of vit d was 21.36±9.23. Conclusion: Hypovitaminosis D is highly prevalent among perimenopausal and post menopausal women in the North eastern part of India. The need for improving the levels of vitamin D among this group of population is both vital and urgent.

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