scholarly journals MANAGEMENT OF LARGE SIZE AND MULTIPLE BENIGN BREAST LESIONS USING ONCOPLASTIC SURGICAL SKILLS

2020 ◽  
Vol 4 (3) ◽  
pp. 6-10
Author(s):  
Saira Saleem ◽  
Farhan Javed ◽  
Irshad Ahmad
Keyword(s):  
Surgical Skills ◽  
Breast Lesions ◽  
Large Size ◽  
Benign Breast Lesions

201Tl Scintigraphy in the Evaluation of Palpable and Nonpalpable Breast Lesions: Correlation with Mammography and Ultrasonography

1997 ◽  
Vol 36 (08) ◽  
pp. 282-288 ◽  
Author(s):  
T. Atasever ◽  
A. Özdemir ◽  
I. Öznur ◽  
N. I. Karabacak ◽  
N. Gökçora ◽  
...  
Keyword(s):  
Final Diagnosis ◽  
Lower Sensitivity ◽  
Breast Lesions ◽  
Breast Cancers ◽  
Combined Use ◽  
Malignant Breast ◽  
Malignant Lesions ◽  
Benign Breast Lesions ◽  
Palpable Breast ◽  
Metastatic Sites

Summary Aim: Our goal was to determine the clinical usefulness of TI-201 to identify breast cancer in patients with suspicious breast lesions on clinical examination, and/or abnormal radiologic (mammography and/or ultrasonography) findings. Methods: TI-201 scintigraphy were performed in sixty-eight patients with 70 breast abnormalities (51 palpable, 19 nonpalpable) and compared with mammography and ultrasonography (US). Early (15 min) and late (3 h) images of the breasts were obtained following the injection of 111 MBq (3 mCi) of TI-201. Visual and semiquantitative interpretation was performed. Results: Final diagnosis confirmed 52 malignant breast lesions and 18 benign conditions. TI-201 visualized 47 of 52 (90%) overall malignant lesions. Thirty-eight of 40 (95%) palpable and 9 of 12 (75%) nonpalpable breast cancers were detected by TI-201 scintigraphy. The smallest mass lesion detected by TI-201 measured 1.5x1.0 cm. Eleven breast lesions were interpreted as indeterminate by mammography and/or sonography. TI-201 scintigraphy excluded malignancy in 7 of 8 (88%) patients with benign breast lesions interpreted as indeterminate. Five of the 18 (28%) benign breast lesions showed TI-201 uptake. None of the fibroadenoma and fibrocystic changes accumulated TI-201. TI-201 scintigraphy, mammography and ultrasonography showed 90%, 92%, 85% overall sensitivity and 72%, 56%, 61% overall specificity respectively. Twenty-one of the 28 (75%) axillary nodal metastatic sites were also detected by TI-201. In malignant and benign lesions, early and late lesion/contralateral normal side (L/N) ratios were 1.58 ± 0.38 (mean ± SD) and 1.48 ± 0.32 (p >0.05), 1.87 ± 0.65 and 1.34 ± 0.20 (p<0.05) respectively. The mean early and late L/N ratios of malignant and benign groups did not show statistical difference (p>0.05). Conclusion: Overall, TI-201 scintigraphy was the most specific of the three methods and yielded favourable results in palpable breast cancers, while it showed lower sensitivity in nonpalpable cancers and axillary metastases. Combined use of TI-201 scintigraphy with mammography and US seems to be useful in difficult cases, such as dense breasts and indeterminate breast lesions.

scholarly journals MRI-Guided Diffuse Optical Spectroscopy of Malignant and Benign Breast Lesions

Neoplasia ◽  
2002 ◽  
Vol 4 (4) ◽  
pp. 347-354 ◽  
Author(s):  
Vasilis Ntziachristos ◽  
A.G. Yodh ◽  
Mitchell D. Schnall ◽  
Britton Chance
Keyword(s):  
Optical Spectroscopy ◽  
Breast Lesions ◽  
Diffuse Optical Spectroscopy ◽  
Benign Breast Lesions ◽  
Mri Guided

scholarly journals SPECTRUM OF BENIGN BREAST LESIONS : A CYTOLOGIC STUDY

2015 ◽  
Vol 4 (54) ◽  
pp. 9305-9312
Author(s):  
Nirmala C ◽  
Shulbha V. Sejekan ◽  
Dayananda B S
Keyword(s):  
Breast Lesions ◽  
Benign Breast Lesions ◽  
Cytologic Study

BENIGN BREAST LESIONS AND OSTEOLYSIS

The Lancet ◽  
1976 ◽  
Vol 307 (7966) ◽  
pp. 970-971 ◽  
Author(s):  
M. Dowsett ◽  
J.C. Gazet ◽  
T.J. Powles ◽  
G.C. Easty ◽  
A.M. Neville
Keyword(s):  
Breast Lesions ◽  
Benign Breast Lesions

P53, Bcl-2 expression and cell proliferation in benign breast lesions

1996 ◽  
Author(s):  
L DiMartino ◽  
E Benini ◽  
A Faranda ◽  
B DeMontis ◽  
G Murenu ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Breast Lesions ◽  
Benign Breast Lesions

scholarly journals Atypical Ductal Lesions of the Breast: Criteria, Significance, and Laboratory Updates

2018 ◽  
Vol 142 (10) ◽  
pp. 1182-1185 ◽  
Author(s):  
Ellen G. East ◽  
Cody S. Carter ◽  
Celina G. Kleer
Keyword(s):  
Diagnostic Criteria ◽  
Clinical Significance ◽  
Atypical Ductal Hyperplasia ◽  
Data Sources ◽  
Molecular Signature ◽  
Breast Lesions ◽  
Architectural Features ◽  
Increased Risk ◽  
Ductal Hyperplasia ◽  
Benign Breast Lesions

Context.— Atypical ductal hyperplasia (ADH) is a challenging diagnosis defined by cytologic and architectural features that carries an increased risk of subsequent carcinoma when diagnosed in isolation. In addition, ADH may secondarily involve benign breast lesions, wherein it carries variable clinical significance. Objectives.— To review the diagnostic criteria and clinical significance of ADH in isolation and as it involves benign breast lesions, and to review the evolving literature on its molecular signature. Data Sources.— Recently published studies that collectively examine ADH were reviewed. Conclusions.— Atypical ductal hyperplasia carries an increased risk of subsequent carcinoma in isolation and when it involves most benign breast lesions. Identifying which cases of ADH will be upgraded to carcinoma has been challenging, and new laboratory developments, such as EZH2 overexpression, may have a future role.

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