scholarly journals PHARMACEUTICAL MARKET ASSORTMENT RESEARCH OF DRUGS FOR VAGINAL USE WITH PROBIOTIC MEDICINES DETAILING

2021 ◽  
Vol 127 (4) ◽  
pp. 55-67
Author(s):  
Svitlana Aleinyk

vaginal route delivery of drugs is an integral part of gynaecological diseases treatment including different genesis vulvovaginitis. The aim of this study it to analyze Ukrainian pharmaceutical market assortment of drugs for vaginal use with probiotic medicines determination. The marketing research was conducted with using of analysis, synthesis, comparison, generalization, content-analysis, statistical, graphical methods. The data of State register of medicines (as of June, 30, 2021), register of wholesale dispensing prices for medicines (as of June, 30, 2021), official web-sites LLC «Morion», «Pharmacy.online», «Compendium.online» were used as objects of the study. As a result, it is determined that as of June 30, 2021 142 medicines for vaginal use are registered on Ukrainian pharmaceutical market with dosage forms, active substances doses, condition for dispensing consideration, 100 brand names, 26 international nonproprietary names, 7 synonymous names. Structural ATC-classification analysis has shown that medicines for vaginal use are included in ATC-groups G «Genito urinary system and sex hormones» and D «Dermatologicals» The assortment macrocontour is formed, it demonstrates that 67,2% of drugs for vaginal use are involved in group G01A «Аntiinfectives and antiseptics, excluding combinations with corticosteroids». More than 80% of drugs for vaginal use are registered as solid dosage forms, and almost half of them as suppositories or pessaries. Almost 65% of medicines are foreign, and 3/4 of them contain only active substance, more than 50% are prescription only medicines. For 44,4% drugs for vaginal use the storage period of 3 years (36 months) is determined. Detailing analysis of medicines with probiotic activity has shown assortment deficiency (only 3 brand names are registered). The liquidity coefficients calculations for this brand manes don’t allow to characterize these drugs as economically affordable. The obtained results of this study inform about the domestic drugs for vaginal use with probiotic activity development relevance, especially in pessaries as dominant dosage form on the pharmaceutical market.

2021 ◽  
Vol 1 (10) ◽  
pp. 47-54
Author(s):  
Aleksandr A. Deltsov ◽  
◽  
Olga R. Rodkina ◽  
Irina V. Kosova ◽  
◽  
...  

This paper presents an analysis of the range of veterinary antiparasitic drugs registered in the territory of the Russian Federation and used for the prevention and treatment of protozoan diseases. At the time of 08/07/2021, 54 antiprotozoal drugs were entered into the State Register of Medicines for Veterinary Use. The most common active ingredient in their composition is Toltrazuril (contained in 12 TN – 22,2%). It was determined that the Russian Federation is a leader in the production and development of anti-protozoal drugs registered on its territory. It was found that most of the investigated drugs are produced in solid dosage forms (35 TN – 64,8%), effective for the treatment of coccidiosis (45 TN – 83,33%) and is used in birds (39 TN – 72,22%). The average annual registration of antiprotozoal drugs is 9% (5 drugs per year).


Author(s):  
S. A. Hladyshevа ◽  
Al Nasir Eiad ◽  
V. V. Luts ◽  
O. P. Hudzenko

Modern research has shown that cognitive impairments are directly related to behavioral disorders and psychopathological syndromes. Nootropic drugs used for pharmacotherapy of cognitive impairments demonstrate low clinical efficiency for the treatment of psychoemotional disorders. In this case, it is advisable to correct such states by prescribing sedatives that have an integrated effect on etiological factors, pathogenetic links and symptomatic manifestations of the disease. The aim of the research was to carry out a comprehensive assortment analysis of sedative drugs within the pharmaceutical market of Ukraine. Materials and methods. Studies were carried out through generally accepted statistical and marketing studies (State Register of Medicines of Ukraine, September, 2020). Our research focused on the information on the structure of the market of sedatives registered in Ukraine. Graphical and logical methods were used in the course of the study. Results. The results of the study have shown that the products manufactured in the Ukrainian pharmaceutical enterprises take 71.50 % of this segment; whereas sedatives produced in Germany – 7.50 %; in Poland – 3.56 %; in Italy, Slovenia, France – 1.50 % for each respectively; in Austria, Malta, Great Britain – 1.02 % for each respectively. The preparations of this group are represented in solid (tablets, coated tablets, capsules, granules, herbs in packs and filter bags) and liquid (tinctures, drops, liquid extracts, elixirs, syrups, oral solutions) dosage forms. Among the studied medicines, solid dosage forms predominate; their share makes 62.7 % of the assortment, and the highest percentage rate is held by tablets (45.5 %). The largest market share of liquid medicinal forms is made by tinctures, in particular 18.9 %. The lowest percentage rates are observed in such medicinal forms as liquid extracts, drops, elixirs, syrups and oral solutions (15.5 % in general). Analysis of the state of the Ukrainian pharmaceutical market of sedatives shows that synthetic drugs account for 24.55 % of the market (tablets – 92.7 %), natural (plant) medicines – 75.45 % (solid dosage forms – 89.6 %). Conclusions. Marketing studies were carried out on the modern market of sedative medicines in Ukraine. It has been established that the quantitative and qualitative diversity of the current assortment is presented by the imported drugs and domestic producers. Analysis of the state of the Ukrainian pharmaceutical market of sedatives was performed. Sedative preparations of natural (plant) origin have been found to be predominant and occupy 2/3 of the total range of sedatives registered in Ukraine as of September, 2020. Synthetic sedative drugs are mainly combined. Monodrugs of plant origin make up the majority of assorted items. Development of drugs aimed at providing complex pharmacotherapeutical correction of cognitive and psychoemotional disorders and based on such peptides as vasopressin, is one of the most significant and relevant problems in modern neurology and is of great scientific and practical value.


2021 ◽  
pp. 66-70
Author(s):  
V. Rybachuk ◽  
Yu. Lyakhovchenko ◽  
A. Yanko

Aim. To analyze the registered medicines of the group of immunostimulants in order to determine the feasibility of creating and organizing the production of new drugs based on natural clays, in particular green and yellow clays.Materials and methods. The list of medicinal products compiled from official sources of information was used in the work; it was processed by the methods of generalization, systematization, graphical method, as well as the methods of comparative and structural analysis.Results and its discussion. The analysis of the Ukrainian pharmaceutical market concerning the range of the registered immunostimulants has been performed. Structuring of the selected list of medicines by the ATC-classification, origin, composition, production characteristic and dosage form type has been carried out. By production basis the majority of medicines are of domestic production (63.58 %). It has been determined that drugs of the segment studied are produced in solid and liquid dosage forms. Solutions for injection are prevalent at the domestic pharmaceutical market, and the range of solid dosage forms is under developed. At the pharmaceutical market, there are no drugs of this group with natural clays, in particular yellow and green clays.Conclusions. The absence of immunostimulants based on natural clays at the Ukrainian market has been proven; it indicates the feasibility of introducing new domestic drugs with the immunostimulating action on the basis of natural clays, in particular yellow and green clays, to the market.


2021 ◽  
Vol 598 ◽  
pp. 120361 ◽  
Author(s):  
S. Henry ◽  
A. Samaro ◽  
F.H. Marchesini ◽  
B. Shaqour ◽  
J. Macedo ◽  
...  

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