scholarly journals Micronucleus in oral exfoliated cells and associated factors among young adults in the far south of Brazil

2021 ◽  
Vol 26 (2) ◽  
pp. 150-162
Author(s):  
Merlyn dos Santos ◽  
Mariana dos Santos ◽  
Caroline Lopes Feijo Fernandes ◽  
Edariane Menestrino Garcia Garcia ◽  
Samuel de Carvalho Dumith ◽  
...  

There is an increasing interest in the application of micronucleus (MN) assays in the clinical setting to investing the impact of environmental, genetic, life style and socioeconomic conditions on DNA. However, the evaluation of mutagenic damage among young population had not been studied and early intervention in this population can prevent several health comorbidities. Thus, the present study aimed in investigate the MN presence in young adults and its associated factors. This is a cross-sectional study, composed by 155 young adults (between 18 to < 30-year-old) of both sexes. The socioeconomic and life style data was collected through a semi-structured questionnaire. Oral exfoliated cells were collected to evaluate the frequency of MN cells. Socioeconomic conditions and life style factors were not associated with the presence of MN. Twenty percent of the participants reported some chronic noncommunicable disease and almost twelve percent reports continued use of medication, both variables present a risk factor to prevalence of MN. Although mutagenesis is a process generally more related to older individuals, this study highlights the importance of monitored DNA damage between young adults and promote healthy habits to prevent the development and worse prognosis of chronic non-transmissible diseases and the consequent use of drugs.

Author(s):  
Dasari Tejaswini ◽  
Suhas Kulkarni ◽  
Dolar Doshi ◽  
Adepu Srilatha

AbstractBackgroundAesthetic alterations in the face can be self-perceived and can affect quality of life in young adults.ObjectiveTo assess the impact of malocclusion on self- perceived oro-facial behaviour among young adults.MethodsA Cross sectional study was conducted among 638 young adults (aged 18–21 years) of Hyderabad city. One college from each of the five zones of the Hyderabad city (five colleges) were selected by simple random sampling procedure. A 21-item Oro-facial investment scale (OFIS) questionnaire assessing self-perceived oral health knowledge, attitude, practice and Dental Aesthetic Index (DAI) assessing the severity of malocclusion was used. Data were analysed with standard statistical software (SPSS, Statistical package for the social sciences, version 20.0). p < 0.05 was considered statistically significant.ResultsMales had higher mean scores for knowledge (2.90 ± 0.49) than females (2.73 ± 0.82) and was statistically significant (p = 0.002*). No statistically significant gender differences were found in relation to attitude and practice. Analysis of variance (ANOVA) showed that there was a significant difference in all the three scores (knowledge, attitude, practice) with respect to age, with significantly high score for knowledge and practice among 18 year old subjects (p = 0.0001*; p = 0.0003* respectively) and attitude among 21 year old subjects (p = 0.0049*). No statistically significant age, gender differences were found in relation to DAI scores. Upon correlation, DAI significantly and positively correlated with knowledge (p = 0.03*) and attitude (p = 0.0001*).ConclusionThis study has shown significant impact of malocclusion on the self-perceived oro-facial behaviour.


2020 ◽  
Vol 34 (4) ◽  
pp. 345-351
Author(s):  
Figen Alp Yilmaz ◽  
Yeter Durgun Ozan

PurposeThe impact of birth beliefs on pregnancy and delivery are universally recognized, but the factors that affect birth beliefs vary across regions depending on individual and cultural characteristics. This study aimed to determine women's birth beliefs and examine their associated factors.Design/methodology/approachThis cross-sectional study was conducted with 548 primiparas in the obstetrics clinic of a university hospital located in the Southeastern Anatolian Region of Turkey from February to June 2019. Descriptive characteristics, form and the Birth Beliefs Scale were used in data collection. To analyze the data, descriptive statistics, T-tests and ANOVA analyses were used.FindingsIt was determined that factors such as age group, income level, any problems during pregnancy and preferred delivery mode statistically affected women's birth beliefs.Originality/valueBased on the findings from this study, healthcare personnel should provide training and consultation services to pregnant women starting from the prenatal period to help ensure a positive labor experience.


2020 ◽  
Vol 70 (6) ◽  
pp. 455-461
Author(s):  
José Obed García‐Cortés ◽  
Jairo Mariel‐Cárdenas ◽  
Ricardo Martinez‐Rider ◽  
Rosalina Islas‐Zarazúa ◽  
Rubén Rosa‐Santillana ◽  
...  

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Enguday Tirfeneh Gebeyehu ◽  
Mengesha Srahbzu Biresaw

Introduction. The impact of alcohol use among adolescents is multidisciplinary and affects the adolescent’s academic performance, precipitates with sexually transmitted infections or psychiatric disorders, and disturbs the social domain of adolescents. Therefore, this study aimed to assess the prevalence and associated factors of alcohol use among adolescents aged 15–19 years at the governmental high schools of Aksum Town, Tigray, Ethiopia, in 2019. Methods. A facility-based cross-sectional study was conducted from 1 to 30 January 2019 at Aksum town high school. Alcohol use was assessed by asking the question “have you used at least one of the alcoholic beverages in the last three months for nonmedical purposes?” Study participants were selected using a simple random sampling technique. Data were collected with face-to-face interview and were analyzed using the Statistical Package for the Social Sciences version 22. Bivariate and multivariate logistic regressions were used to see the association between alcohol use and associated factors. Adjusted odds ratio at a p value < 0.05 with a 95% confidence interval was taken to declare the statistical significance of variables. Result. About 633 adolescents aged 15–19 years were addressed with a response rate of 99.7%. Prevalence of alcohol use was found to be 39.7% [95% CI (35.7, 43.6)]. Being male [AOR = 1.80; 95% CI (1.24, 2.60)], fathers’ educational status 1–8 grades [AOR = 2.98; 95% CI (1.60, 5.53)], fathers’ occupation farming [AOR = 4.24; 95% CI (2.038.85)], experienced parental neglect [AOR = 1.75; 95% CI (1.20, 2.55)], strong social support [AOR = 1.79; 95% CI (1.11, 2.87)], and family size of greater than five [AOR = 2.03; 95%CI (1.39, 2.97)] were factors identified to be significantly associated with alcohol use among adolescents aged 15–19 years. Conclusion. In the current study, the prevalence of alcohol use is found to be high when compared to other populations. A strong association has been found between alcohol use and lower paternal educational status and farming as an occupation of parents. There should be a regular awareness creation program for parents with lower education about the devastating effects of alcohol on adolescents.


2020 ◽  
Author(s):  
Xiaoxiao Chen ◽  
Qian Xu ◽  
Haijiang Lin ◽  
Jianfu Zhu ◽  
Yue Chen ◽  
...  

Abstract Background: The COVID-19 related lockdown and home confinement might have an important impact on the quality of life in enterprise workers. We investigated the quality of life during the epidemic in enterprise workers who just returned to work, and assessed its potential influencing factors to have a better understanding of the impact of COVID-19 epidemic lockdown and home confinement. Methods: This was a cross-sectional study of enterprise workers conducted in Deqing and Taizhou, Zhejiang Province, China. The Chinese version of EQ5D was used to assess life quality, and information about general characteristics and COVID-19 related factors was collected by a structured questionnaire, which was distributed through the social application “WeChat”. Results: A total of 2,435 participants were enrolled, 59.5% of which worked in Deqing. About 50% of the participants reported worries about the COVID-2019 epidemic and 40.1% had a centralized or home quarantine during the epidemic. The mean EQ-5D score and VAS were 0.990 and 93.5. Multiple logistic regression showed that the quality of life measures was related to physical activities (ORad=0.46) and keeping home ventilation (ORad=0.04) in Deqing, and were related to wearing a mask when going out (ORad=0.35), keeping home ventilation (ORad=0.16), unmarried status (ORad=2.38) and having a centralized or home quarantine (ORad=1.64) in Taizhou,Conclusions: The quality of life for returning enterprise workers in areas with different risks of COVID-19 was affected by different factors. Associated factors identified from this study would help develop proper intervention measures for enterprise workers to reduce the impact of large-scale public health events like the COVID-19 on their quality of life.


2020 ◽  
Author(s):  
Tsegaye Adane Birhan ◽  
Walelegn Worku ◽  
Jember Azanaw ◽  
Lamrot Yohannes

Abstract Background: Globally, khat chewing practice becoming an alarming and common among the youth generation especially in higher educational institutions. It may also leads to frequent misbehavior, poor academic performance and memory impairment among students. This study aimed to determine the prevalence of khat chewing and associated factors among medical students in University of Gondar, Northwest Ethiopia, 2019.Method: An institution-based cross-sectional study was employed on 422 medical students. Data were collected using a self-administered questionnaire and analyzed using SPSS 20 software. Stratified followed by random sampling was employed to select the samples. Multivariable logistic regression model was fitted to identify the predictors. P ≤ 0.05 was used to select statistically significant factors.Result: The current prevalence of khat chewing among medical students was 21.5%. The odds of khat chewing was higher among males [AOR=3.353; 95%CI (1.460-7.701)], Muslims [AOR=6.390; 95%CI (1.903-21.460)], fifth and six year students [AOR= 3.391; 95%CI (1.354-8.488)], smokers [AOR=5.081; 95%CI (1.898-13.601)], alcohol users [AOR=4.872; 95%CI (2.094-11.332)], students who had khat chewer close friends [AOR=30.645; 95%CI (12.261-76.589)].Conclusion: Since a significant proportion of students chew khat, continuous awareness creation on the impact of khat chewing and counseling services are recommended.


2020 ◽  
Author(s):  
Xiaoxiao Chen ◽  
Qian Xu ◽  
Haijiang Lin ◽  
Jianfu Zhu ◽  
Yue Chen ◽  
...  

Abstract Background: The COVID-19 related lockdown and home confinement might have an important impact on the quality of life in enterprise workers. We investigated the quality of life during the epidemic in enterprise workers who just returned to work, and assessed its potential influencing factors to have a better understanding of the impact of COVID-19 epidemic lockdown and home confinement.Methods: This was a cross-sectional study of enterprise workers conducted in Deqing and Taizhou, Zhejiang Province, China. The Chinese version of EQ5D was used to assess life quality, and information about general characteristics and COVID-19 related factors was collected by a structured questionnaire, which was distributed through the social application “WeChat”.Results: A total of 2,435 participants were enrolled, 59.5% of which worked in Deqing. About 50% of the participants reported worries about the COVID-2019 epidemic and 40.1% had a centralized or home quarantine during the epidemic. The mean EQ-5D score and VAS were 0.990 and 93.5. Multiple logistic regression showed that the quality of life measures was related to physical activities (ORad=0.46) and keeping home ventilation (ORad=0.04) in Deqing, and were related to wearing a mask when going out (ORad=0.35), keeping home ventilation (ORad=0.16), unmarried status (ORad=2.38) and having a centralized or home quarantine (ORad=1.64) in Taizhou,Conclusions: The quality of life for returning enterprise workers in areas with different risks of COVID-19 was affected by different factors. Associated factors identified from this study would help develop proper intervention measures for enterprise workers to reduce the impact of large-scale public health events like the COVID-19 on their quality of life.


Author(s):  
Jungwon Cho ◽  
Seungyeon Kim ◽  
Sangyoon Shin ◽  
Hyejin Yoo ◽  
Gi Hyue Park ◽  
...  

Studies have documented the impact of various types of health care information technology (HIT) on patient outcomes. However, literature on the HIT products is largely for outpatients and little is known about those for hospitalized patients. In 2014, a Korean hospital developed an inpatient portal known as the Smart Bedside Station (SBS). A retrospective cross-sectional study was conducted to evaluate the associated factors for accessing the medication view menu (Today’s Medication) on the SBS using data from October 2018 through September 2019. A root cause analysis with expert review was conducted to identify additional barriers for accessing the medication view menu. Approximately 92.58% of the study population accessed the SBS at least once during their hospital stay. However, 99.20% of accessed patients used the SBS for entertainment purposes (e.g., television) and 40.16% viewed the medication information. Younger age, higher education, and certain jobs were significant associated factors for accessing the medication information. In conclusion, this study revealed strong associations between accessing the medication view menu on the SBS and a number of associated factors. Based on the results, further research is warranted to suggest new items to access the medication view menu by hospitalized patients.


Sign in / Sign up

Export Citation Format

Share Document