scholarly journals ASSESSMENT OF CARDIAC IRON OVERLOAD IN MULTIPLY TRANSFUSED THALASSEMIC CHILDREN USING T2* WEIGHTED CARDIAC MAGNETIC RESONANCE

2015 ◽  
Vol 02 (04) ◽  
pp. 169-172 ◽  
Author(s):  
Sambhaji Chandrakant Chate ◽  
Mamta Manglani ◽  
Mona Pate ◽  
Bhavin Jankharia
Keyword(s):  
Cardiac Magnetic Resonance ◽  
Magnetic Resonance ◽  
Iron Overload ◽  
Cardiac Iron ◽  
Cardiac Iron Overload

Evaluation of cardiac iron overload in transfusion-dependent adult marrow failure patients by magnetic resonance imaging

2009 ◽  
Vol 33 (6) ◽  
pp. 756-758 ◽  
Author(s):  
Jinho Park ◽  
Kazuma Ohyashiki ◽  
Soichi Akata ◽  
Kenichi Takara ◽  
Ritsuko Uno ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Iron Overload ◽  
Resonance Imaging ◽  
Cardiac Iron ◽  
Cardiac Iron Overload

scholarly journals Cardiac iron overload assessed by T2* magnetic resonance imaging and cardiac function in regularly transfused myelodysplastic syndrome patients

2013 ◽  
Vol 162 (3) ◽  
pp. 413-415 ◽  
Author(s):  
Laurent Pascal ◽  
Odile Beyne-Rauzy ◽  
Sabine Brechignac ◽  
Sylvestre Marechaux ◽  
Dominique Vassilieff ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Cardiac Function ◽  
Myelodysplastic Syndrome ◽  
Iron Overload ◽  
Resonance Imaging ◽  
Cardiac Iron ◽  
Cardiac Iron Overload

scholarly journals Prevention of Cardiomyopathy in Transfusion-Dependent Homozygous Thalassaemia Today and the Role of Cardiac Magnetic Resonance Imaging

2009 ◽  
Vol 2009 ◽  
pp. 1-4 ◽  
Author(s):  
Athanassios Aessopos ◽  
Vasilios Berdoukas ◽  
Maria Tsironi
Keyword(s):  
Magnetic Resonance Imaging ◽  
Cardiac Magnetic Resonance ◽  
Magnetic Resonance ◽  
Cardiac Magnetic Resonance Imaging ◽  
Cardiac Disease ◽  
Iron Status ◽  
Iron Chelation ◽  
Resonance Imaging ◽  
Cardiac Iron ◽  
Cardiac Iron Overload

Transfusion and iron chelation therapy revolutionised survival and reduced morbidity in patients with transfusion-dependent beta thalassaemia major. Despite these improvements, cardiac disease remained the most common cause of death in those patients. Recently the ability to determine the degree of cardiac iron overload, through cardiac magnetic resonance imaging (CMR) has allowed more logical approaches to iron removal, particularly from the heart. The availability of two oral chelators, deferiprone and deferasirox has reduced the need for the injectable chelator deferrioxamine and an additional benefit has been that deferiprone has been shown to be more cardioprotective than deferrioxamine. This review on the prevention of cardiac disease makes recommendations on the chelation regime that would be desirable for patients according to their cardiac iron status as determined by CMR determined by CMR. It also discusses approaches to chelation management should CMR not be available.

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