scholarly journals Features of the Clinical Course of Arterial Hypotension in Pregnant Women

2022 ◽  
Vol 8 (1) ◽  
pp. 154-159
Author(s):  
A. Subanova
Keyword(s):  
Clinical Course ◽  
The Body ◽  
Arterial Hypotension ◽  
Pathological State ◽  
Mountainous Terrain ◽  
Hemodynamic Changes ◽  
Systemic Hemodynamic ◽  
Placental Function ◽  
Climatic Regions ◽  
Hematopoietic Organs

A study was carried out of women with arterial hypotension against the background of the development of the pathological state of the fetus and newborns born to women living in two different climatic regions of Osh city and in the highlands of Chon-Alay district of Osh region. In the pathogenesis of pregnancy complications caused by arterial hypotension, the leading importance is attached to vascular disorders and microcirculation disorders, leading to systemic hemodynamic changes in the body of a pregnant woman. It was found that in mountainous terrain, arterial hypotension and exogenous hypoxia affect the “mother–placenta–fetus–newborn” system, increasing the load on the respiratory, circulatory and hematopoietic organs of the mother, and also leads to impaired placental function.

The clinical course and role of surgery in pediatric malignant peripheral nerve sheath tumors: a database study

2021 ◽  
pp. 1-8
Author(s):  
Victor M. Lu ◽  
Shelly Wang ◽  
David J. Daniels ◽  
Robert J. Spinner ◽  
Allan D. Levi ◽  
...  
Keyword(s):  
Overall Survival ◽  
Radiation Therapy ◽  
Peripheral Nerve ◽  
Pediatric Patients ◽  
Clinical Course ◽  
The Body ◽  
National Database ◽  
Nerve Sheath Tumors ◽  
Peripheral Nerve Sheath Tumors ◽  
Nerve Sheath

OBJECTIVE Malignant peripheral nerve sheath tumors (MPNSTs) are rare tumors found throughout the body, with their clinical course in children still not completely understood. Correspondingly, this study aimed to determine survival outcomes and specific clinical predictors of survival in this population from a large national database. METHODS All patients with MPNSTs aged ≤ 18 years in the US National Cancer Database (NCDB) between 2005 and 2016 were retrospectively reviewed. Data were summarized, and overall survival was modeled using Kaplan-Meier and Cox regression analyses. RESULTS A total of 251 pediatric patients with MPNSTs (132 [53%] females and 119 [47%] males) were identified; the mean age at diagnosis was 13.1 years (range 1–18 years). There were 84 (33%) MPNSTs located in the extremities, 127 (51%) were smaller than 1 cm, and 22 (9%) had metastasis at the time of diagnosis. In terms of treatment, surgery was pursued in 187 patients (74%), chemotherapy in 116 patients (46%), and radiation therapy in 129 patients (61%). The 5-year overall survival rate was estimated at 52% (95% CI 45%–59%), with a median survival of 64 months (range 36–136 months). Multivariate regression revealed that older age (HR 1.10, p < 0.01), metastases at the time of diagnosis (HR 2.14, p = 0.01), and undergoing biopsy only (HR 2.98, p < 0.01) significantly and independently predicted a shorter overall survival. Chemotherapy and radiation therapy were not statistically significant. CONCLUSIONS In this study, the authors found that older patient age, tumor metastases at the time of diagnosis, and undergoing only biopsy significantly and independently predicted poorer outcomes. Only approximately half of patients survived to 5 years. These results have shown a clear survival benefit in pursuing maximal safe resection in pediatric patients with MPNSTs. As such, judicious workup with meticulous resection by an expert team should be considered the standard of care for these tumors in children.

scholarly journals Factors affecting the course of body and kidney growth in infants with urolithiasis: A critical long-term evaluation

2016 ◽  
Vol 88 (4) ◽  
pp. 249 ◽  
Author(s):  
Kemal Sarica ◽  
Fatma Narter ◽  
Kubilay Sabuncu ◽  
Ahmet Akca ◽  
Utku Can ◽  
...  
Keyword(s):  
Breast Feeding ◽  
Clinical Course ◽  
Stone Disease ◽  
The Body ◽  
Renal Growth ◽  
Related Factors ◽  
Growth Status ◽  
Long Term Follow Up

Objective: To investigate the possible effects of dietary, patient and stone related factors on the clinical course of the stone disease as well as the body and renal growth status of the infants. Patients and Methods: A total of 50 children with an history of stone disease during infancy period were studied. Patient (anatomical abnormalities, urinary tract infection - UTI, associated morbidities), stone (obstruction, UTI and required interventions) and lastly dietary (duration of sole breast feeding, formula feeding) related factors which may affect the clinical course of the disease were all evaluated for their effects on the body and renal growth during long-term follow-up. Results: Mean age of the children was 2.40 ± 2.65 years. Our findings demonstrated that infants receiving longer period of breast feeding without formula addition seemed to have a higher rate of normal growth percentile values when compared with the other children. Again, higher frequency of UTI and stone attacks affected the growth status of the infants in a remarkable manner than the other cases. Our findings also demonstrated that thorough a close follow-up and appropriately taken measures; the possible growth retardation as well as renal growth problems could be avoided in children beginning to suffer from stone disease during infancy period. Conclusions: Duration of breast feeding, frequency of UTI, number of stone attacks and stone removal procedures are crucial factors for the clinical course of stone disease in infants that may affect the body as well as kidney growth during long-term follow-up.

Experience of using the stalagmometric method of urine research in gynecology and obstetrics

1926 ◽  
Vol 22 (4) ◽  
pp. 408-413
Author(s):  
B. S. Tarlo
Keyword(s):  
The Body ◽  
Pathological State ◽  
Gynecology And Obstetrics

It is known that, under normal conditions, urine contains almost no colloidal substances, and their appearance in a more noticeable amount indicates a pathological state of the body. It would therefore be important to have at our disposal a method with which it would be possible to discover these substances not only qualitatively, but also quantitatively.

Systemic hemodynamic changes in mansonic schistosomiasis with portal hypertension treated by azygoportal disconnection and splenectomy

1999 ◽  
Vol 94 (6) ◽  
pp. 1632-1637 ◽  
Author(s):  
Roberto Cleva ◽  
Vincenzo Pugliese ◽  
Bruno Zilberstein ◽  
William Abrao Saad ◽  
Henrique Walter Pinotti ◽  
...  
Keyword(s):  
Portal Hypertension ◽  
Hemodynamic Changes ◽  
Systemic Hemodynamic

Lunato-Triquetral Fusion and Associated Spinal Abnormality

HAND ◽  
1982 ◽  
Vol os-14 (1) ◽  
pp. 89-92 ◽  
Author(s):  
D. H. Thakkar
Keyword(s):  
Clinical Course ◽  
English Literature ◽  
The Body ◽  
Dominant Hand ◽  
Upper Limbs ◽  
Rare Congenital Anomaly ◽  
X Ray ◽  
Skeletal Dysplasias ◽  
The Past ◽  
Spinal Abnormality

Lunato-triquetral fusion is a rare congenital anomaly. Its association with skeletal dysplasias, tarsal coalitions and synostotic states in the upper limbs and other parts of the body is well established. There is no mention in the English literature about its association with congenital spinal abnormalities and secondary osteoarthrosis in the wrist and two such cases are now described. Both cases presented with symptoms in the dominant hand and had symptoms of backache in the past. Their clinical course and X-ray findings are described.

scholarly journals Systemic Hemodynamic Changes in Elderly Hypertensive Patients After Ingesting Foods With Lipid, Protein, and Carbohydrate Contents

2009 ◽  
Vol 11 (5) ◽  
pp. 271-276 ◽  
Author(s):  
Sebastião R. Ferreira-Filho ◽  
Anna Carolina C. R. Ferreira ◽  
Paulo C. Oliveira ◽  
Jorge F. M. Moreira ◽  
Eduardo C. Ribeiro ◽  
...  
Keyword(s):  
Hemodynamic Changes ◽  
Systemic Hemodynamic ◽  
Hypertensive Patients ◽  
Elderly Hypertensive ◽  
Elderly Hypertensive Patients ◽  
Carbohydrate Contents

Intravenous AICAR During Hyperinsulinemia Induces Systemic Hemodynamic Changes but Has No Local Metabolic Effect

2011 ◽  
Vol 51 (10) ◽  
pp. 1449-1458 ◽  
Author(s):  
Marlies Bosselaar ◽  
Paul Smits ◽  
Luc J. C. van Loon ◽  
Cees J. Tack
Keyword(s):  
Metabolic Effect ◽  
Hemodynamic Changes ◽  
Systemic Hemodynamic

scholarly journals Embolic Stroke Caused by Staphylococcus lugdunensis Endocarditis Complicating Vasectomy in a 36-Year-Old Man

2015 ◽  
Vol 42 (6) ◽  
pp. 585-587 ◽  
Author(s):  
Manova David ◽  
Megan Loftsgaarden ◽  
Felix Chukwudelunzu
Keyword(s):  
At Risk ◽  
Medical Literature ◽  
Clinical Course ◽  
The Body ◽  
Embolic Stroke ◽  
Inguinal Region ◽  
Staphylococcus Lugdunensis ◽  
Native Valve ◽  
Native Flora ◽  
Native Valve Endocarditis

Staphylococcus lugdunensis is part of the native flora in the inguinal region of the body. Inguinal surgeries, such as vasectomy, place carriers of this aggressive pathogen at risk for contamination. Native-valve endocarditis caused by coagulase-negative S. lugdunensis has a rapid and complicated clinical course. The pathogenicity of this organism is not limited to cardiac valvular destruction. We report the case of a 36-year-old man who presented with S. lugdunensis endocarditis, dysarthria, and hemiparesis 5 weeks after a vasectomy. To our knowledge, this is the first report of embolic stroke caused by S. lugdunensis endocarditis. In addition, we discuss the relevant medical literature.

scholarly journals Temperature management and its role in cardiac arrest patients—a review

2021 ◽  
Keyword(s):  
Cardiac Arrest ◽  
The Body ◽  
Temperature Management ◽  
Additional Stress ◽  
Pathological State ◽  
Temperature Homeostasis ◽  
Thermoregulatory System ◽  
Common Application ◽  
Cardiac Arrest Survival ◽  
Hospital Cardiac Arrest

Thermoregulation constitutes one of the most important homeostatic systems of the human body. The human thermoregulatory system is highly complex and intertwined with other regulatory homeostatic systems. Different evolutionary adaptations have evolved to ensure a well-regulated body temperature, encompassing simple behavioural (e.g., seeking shelter, going underground) as well as physiological changes (e.g., vasodilatation, sweating). However, when the heat, cold or other stimuli cause a disruption in the thermoregulatory state and our adaptations can no longer cope with the additional stress, the body enters a pathological state. In such instances other measures must be undertaken. In medicine there are several pathological states associated with disruptions in temperature homeostasis. Consequently, these patients have to be, in broad terms, thermoregulated. Speaking specifically, the most common application of thermoregulation is therapeutic temperature management. A prominent example is the utilisation of this technique in post-cardiac arrest patients, who remain comatose after resuscitation. This technique has been in use for almost 20 years since the first major reports on its benefits in improving out-of-hospital cardiac arrest and in-hospital cardiac arrest survival as well as improving neurological outcome. Recently, the findings from one of the biggest targeted temperature international and multicentre trials to date have been published (TTM2 trial; https://ttm2trial.org/). The study surprisingly showed no difference in mortality between patients after out of hospital cardiac arrest, who underwent normo- or hypothermia. Consequently, we might need to re-evaluate certain guidelines, recommendations, and perspectives. The aim of the current review is to present an overview of targeted temperature management in the field of intensive care medicine and cardiac arrest.

scholarly journals THE ROLE OF ASSESSMENT AND CORRECTION OF NUTRITIONAL STATUS IN A COMPREHENSIVE APPROACH TO COVID-19 PATIENT WITH METABOLIC DISORDERS: Review

2021 ◽  
Vol 8 (3) ◽  
pp. 152-156
Author(s):  
S.V. Ivanchenko ◽  
O.M. Kovalyova ◽  
A.B. Andrusha
Keyword(s):  
Nutritional Status ◽  
Inpatient Treatment ◽  
Metabolic Disorders ◽  
Clinical Course ◽  
Respiratory Infections ◽  
The Body ◽  
Analytical Review ◽  
Human Immune ◽  
The Relationship

The article is devoted to the problem of coronavirus disease COVID-19 with emphasis on the nutritional status of patients. An analytical review of recent publications related to aspects of nutritional support for people in outpatient and inpatient treatment for COVID-19 is presented. The article highlights the pathogenetic justification of the relationship between the immune response and metabolic balance of the body, the optimal content of trace elements, vitamins, components of lipid metabolism. The importance of nutrition as a strategy to support human immune function is considered. Methods for determining the adequate energy balance of patients with severe COVID-19 are presented. Groups of foods and key nutrients that may affect the consequences and clinical course of respiratory infections are described. The importance of assessing and optimizing nutritional status to improve the clinical course and consequences of COVID-19 in patients with comorbid pre-existing non-communicable diseases, such as diabetes, cardiovascular disease, obesity with systemic inflammation, is emphasized.

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