scholarly journals Ultrasonic assessment of the distribution of tricalcium phosphate filler over the volume of swollen porous matrices based on chitosan for biomedical applications

Biomeditsina ◽  
2021 ◽  
Vol 17 (3E) ◽  
pp. 42-47
Author(s):  
O. R. Kulikova ◽  
E. A. Khramtsova ◽  
K. G. Antipova ◽  
T. D. Patsaev ◽  
E. S. Morokov ◽  
...  

Regenerative medicine is a rapidly developing interdisciplinary field of science. Of primary interest are new materials and mechanisms of their interaction with living organisms. Investigation methods should provide 3D visualization and analysis of quantitative characteristics, while having no effect on the objects under study. For these purposes, methods based on ultrasound and those displaying variations in the elastic properties of samples are promising. 

2021 ◽  
Vol 17 ◽  
Author(s):  
Grigoriy Sereda ◽  
Md Tusar Uddin ◽  
Jacob Wente

Background: The unique ability of carbon to form a wide variety of allotrope modifications has ushered a new era in the material science. Tuning the properties of these materials by functionalization is a must-have tool for their design customized for a specific practical use. The exponentially growing computational power available to researchers allows for the prediction and thorough understanding of the underlying physico-chemical processes responsible for the practical properties of pristine and modified carbons using the methods of quantum chemistry. Method: This review focuses on the computational assessment of the influence of functionalization on the properties of carbons and enabling desired practical properties of the new materials. The first section of each part of this review focuses on graphene - nearly planar units built from sp2-carbons. The second section discusses patterns of sp2-carbons rolled-up into curved 3D-structures in a variety of ways (fullerenes). The overview of other types of carbonaceous materials including those with a high abundance of sp3-carbons, including nanodiamonds, can be found in the third section of each manuscript’s part. Conclusion: The computational methods are especially critical for predicting electronic properties of materials such as the band gap, conductivity, optical and photoelectronic properties, solubility, adsorptivity, potential for catalysis, sensing, imaging and biomedical applications. We expect that introduction of defects to carbonaceous materials as a type of their functionalization will be a point of growth in this area of computational research.


2018 ◽  
Vol 2018 ◽  
pp. 1-12 ◽  
Author(s):  
Ziyu Ge ◽  
Luming Yang ◽  
Fang Xiao ◽  
Yani Wu ◽  
Tingting Yu ◽  
...  

Graphene family nanomaterials, with superior mechanical, chemical, and biological properties, have grabbed appreciable attention on the path of researches seeking new materials for future biomedical applications. Although potential applications of graphene had been highly reviewed in other fields of medicine, especially for their antibacterial properties and tissue regenerative capacities, in vivo and in vitro studies related to dentistry are very limited. Therefore, based on current knowledge and latest progress, this article aimed to present the recent achievements and provide a comprehensive literature review on potential applications of graphene that could be translated into clinical reality in dentistry.


Crystals ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. 117 ◽  
Author(s):  
Donata Konopacka-Łyskawa ◽  
Natalia Czaplicka ◽  
Barbara Kościelska ◽  
Marcin Łapiński ◽  
Jacek Gębicki

Calcium carbonate is a compound existing in living organisms and produced for many biomedical applications. In this work, calcium carbonate was synthesized by a CO2 bubbling method using ammonia as a CO2 absorption promotor. Glucose, fructose, sucrose, and trehalose were added into the reaction mixture to modify characteristics of precipitated calcium carbonate particles. To determine the polymorphic form of produced calcium carbonate particles, Fourier transform infrared spectroscopy (FTIR-ATR) and X-ray diffraction (XRD) analysis were performed. Scanning electron microscopy (SEM) was used to estimate the size and shape of produced particles. Mixtures of vaterite and calcite were synthesized in all experiments. The percentage content of the vaterite in the samples depended on used additive. The highest concentration of vaterite (90%) was produced from a solution containing sucrose, while the lowest concentration (2%) was when fructose was added. Saccharides affected the rate of CO2 absorption, which resulted in a change in the precipitation rate and, therefore, the polymorphic composition of calcium carbonate obtained in the presence of saccharides was more varied.


2020 ◽  
Vol 8 (15) ◽  
pp. 2930-2950 ◽  
Author(s):  
Hiroyuki Tetsuka ◽  
Su Ryon Shin

This review highlights the recent advancements of new materials and 3D printing techniques developed to address the unfulfilled needs of the conventional 3D printing methodologies in biomedical applications.


2020 ◽  
Vol 27 ◽  
Author(s):  
Keru Shi ◽  
Xinyi Xu ◽  
Hanrui Li ◽  
Hui Xie ◽  
Xueli Chen ◽  
...  

: Quantum dots (QDs), whose diameters are often limited to 10 nm, have been of interest to researchers for their unique optical characteristics, which are attributed to quantum confinement. Following their early application in the electrical industry as light-emitting diode materials, semiconductor nanocrystals have continued to show great potential in clinical diagnosis and biomedical applications. The conventional physical and chemical pathways for QD syntheses typically require harsh conditions and hazardous reagents, and these products encounter non-hydrophilic problems due to organic capping ligands when they enter the physiological environment. The natural reducing abilities of living organisms, especially microbes, are then exploited to prepare QDs from available metal precursors. Low-cost and eco-friendly biosynthesis approaches have the potential for further biomedical applications which benefit from the good biocompatibility of protein-coated QDs. The surface biomass offers many binding sites for modifying substances or targeting ligands and so achieving multiple functions through simple and efficient operations. Biosynthetic QDs could function as bioimaging and biolabeling agents because of their luminescence properties similar to those of chemical QDs. In addition, extensive research has been carried out on the antibacterial activity, metal ion detection and bioremediation. As a result, this review details the advanced progress of biomedical applications of biosynthesized QDs and illustrates these principles as clearly as possible.


2020 ◽  
Vol 26 (33) ◽  
pp. 4032-4047
Author(s):  
Adriana N. dos Santos ◽  
Tatiana R. de L. Nascimento ◽  
Brenna L. C. Gondim ◽  
Marilia M. A. C. Velo ◽  
Renaly I. de A. Rêgo ◽  
...  

Research regarding polyphenols has gained prominence over the years because of their potential as pharmacological nutrients. Most polyphenols are flavanols, commonly known as catechins, which are present in high amounts in green tea. Catechins are promising candidates in the field of biomedicine. The health benefits of catechins, notably their antioxidant effects, are related to their chemical structure and the total number of hydroxyl groups. In addition, catechins possess strong activities against several pathogens, including bacteria, viruses, parasites, and fungi. One major limitation of these compounds is low bioavailability. Catechins are poorly absorbed by intestinal barriers. Some protective mechanisms may be required to maintain or even increase the stability and bioavailability of these molecules within living organisms. Moreover, novel delivery systems, such as scaffolds, fibers, sponges, and capsules, have been proposed. This review focuses on the unique structures and bioactive properties of catechins and their role in inflammatory responses as well as provides a perspective on their use in future human health applications.


Elements ◽  
2021 ◽  
Vol 17 (3) ◽  
pp. 189-194
Author(s):  
Gilberto Artioli ◽  
Daniel S. Hussey

By exploiting the penetration, attenuation, and scattering properties of neutrons, images of matter in two or three dimensions reveal information unobtainable using other probes. Despite the limitation in brilliance of neutron sources, several neutron-based imaging techniques are essential to different aspects of modern geoscience. Typical examples include the evaluation of porosity in rocks and sediments, mapping of light elements in solids, noninvasive probing of cultural heritage objects, investigations of thick engineering components, and the exploration of diffusion and percolation processes of fluids within porous matrices, organo-inorganic composites, and living organisms. Techniques under development include simultaneous neutron and X-ray tomography in heterogeneous media, Bragg-edge imaging, and the possibility of porosimetry from dark-field imaging.


2020 ◽  
Vol 4 (2) ◽  
pp. 489-506 ◽  
Author(s):  
Yan Zhang ◽  
Yunchuan Qi ◽  
Sébastien Ulrich ◽  
Mihail Barboiu ◽  
Olof Ramström

Dynamic covalent polymers have emerged as intriguing, new materials with unique properties. In this article, their synthesis, properties, and applications in the biomedical field have been reviewed.


MRS Bulletin ◽  
2000 ◽  
Vol 25 (4) ◽  
pp. 49-53 ◽  
Author(s):  
Luc Brunsveld ◽  
Brigitte J. B. Folmer ◽  
E. W. Meijer

What started as a scientific challenge roughly 10 years ago has become a technological reality today, as materials from supramolecular polymers and their many applications as smart materials have emerged. Synthetic polymeric materials are among the most important classes of new materials introduced in the 20th century. They are primarily used for construction, but electronic and biomedical applications are also at the forefront of science and technology.


2014 ◽  
Vol 2014 ◽  
pp. 1-13 ◽  
Author(s):  
Gaurav Lodhi ◽  
Yon-Suk Kim ◽  
Jin-Woo Hwang ◽  
Se-Kwon Kim ◽  
You-Jin Jeon ◽  
...  

Chitin is a natural polysaccharide of major importance. This biopolymer is synthesized by an enormous number of living organisms; considering the amount of chitin produced annually in the world, it is the most abundant polymer after cellulose. The most important derivative of chitin is chitosan, obtained by partial deacetylation of chitin under alkaline conditions or by enzymatic hydrolysis. Chitin and chitosan are known to have important functional activities but poor solubility makes them difficult to use in food and biomedicinal applications. Chitooligosaccharides (COS) are the degraded products of chitosan or chitin prepared by enzymatic or chemical hydrolysis of chitosan. The greater solubility and low viscosity of COS have attracted the interest of many researchers to utilize COS and their derivatives for various biomedical applications. In light of the recent interest in the biomedical applications of chitin, chitosan, and their derivatives, this review focuses on the preparation and biological activities of chitin, chitosan, COS, and their derivatives.


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