scholarly journals Protein-Inorganic Hybrid Nanoflowers as Efficient Biomimetic Antibiotics in the Treatment of Bacterial Infection

2021 ◽  
Vol 9 ◽  
Author(s):  
Ying Zhou ◽  
Ying Li ◽  
Yunwei Fei ◽  
Mingrui Zhang ◽  
Shuang Wang ◽  
...  
Keyword(s):  
Bacterial Infection ◽  
Tissue Injury ◽  
Raw Materials ◽  
Metal Species ◽  
New Paradigm ◽  
Inorganic Hybrid ◽  
Inorganic Particles ◽  
Physiological Conditions ◽  
Copper Phosphate ◽  
New Generation

Nanozymes have been developed as new generation of biomimetic antibiotics against wound infection. However, most of new-developed nanozymes based on inorganic particles or hybrid ones usually originate from incompatible raw materials or unwanted metal salts, highly limiting their further biomedical usages. To overcome above drawbacks, it is highly required to develop novel nanozymes with great antibacterial activity by using biocompatible reagents and endogenous metal species as raw materials. Here, we demonstrated that bovine serum albumin enwrapped copper phosphate-based protein-inorganic hybrid nanoflowers possessed intrinsic peroxidase-like activity, which could be used as efficient biomimetic antibiotics against bacterial infection via the nanozyme-mediated generation of high toxic reactive oxygen species (ROS). With the admirable peroxidase-like activity, our nanoflowers could efficiently kill drug-resistance bacteria under physiological conditions, improve the wound healing after pathogen-induced infection, as well as avoid the potential tissue injury in time. Comprehensive toxicity exploration of these nanoflowers indicated their high biocompatibility and excellent biosafety. Our current strategy toward the design of protein-inorganic hybrid nanozymes with high biosafety and few side effects could provide a new paradigm for the development of nanozyme-based antibacterial platform in future.

Overcoming stereotypes of renewable energy

2019 ◽  
pp. 124-136
Author(s):  
Victor D. Gazman
Keyword(s):  
Renewable Energy ◽  
Empirical Analysis ◽  
Energy Generation ◽  
New Paradigm ◽  
Financial Instrument ◽  
Promising Direction ◽  
Investment Projects ◽  
Power Stations ◽  
New Generation ◽  
The Impact

The article considers prerequisites for the formation of a new paradigm in the energy sector. The factors that may affect the imminent change of leadership among the energy generation are analyzed. The variability of the projects of creation and functioning of power stations is examined. The focus is made on problematic aspects of the new generation, especially, storage and supply of energy, achieving a system of parity that ensures balance in pricing generations. The author substantiates the principles of forming system of parities arising when comparing traditional and new generations. The article presents the results of an empirical analysis of the 215 projects for the construction of facilities for renewable energy. The significance and direction of the impact of these factors on the growth in investment volumes of transactions are determined. The author considers leasing as an effective financial instrument for overcoming stereotypes of renewable energy and as a promising direction for accelerated implementation of investment projects.

The sugar and alcohol industry in the biofuels and cogeneration era: a paradigm change (part II)

2014 ◽  
pp. 97-104 ◽  
Author(s):  
Electo Eduardo Silv Lora ◽  
Mateus Henrique Rocha ◽  
José Carlos Escobar Palacio ◽  
Osvaldo José Venturini ◽  
Maria Luiza Grillo Renó ◽  
...  
Keyword(s):  
Large Scale ◽  
New Technologies ◽  
Process Integration ◽  
Animal Feed ◽  
Raw Materials ◽  
Biofuel Production ◽  
New Paradigm ◽  
Alcohol Industry ◽  
Feed Production ◽  
Steam Parameters

The aim of this paper is to discuss the major technological changes related to the implementation of large-scale cogeneration and biofuel production in the sugar and alcohol industry. The reduction of the process steam consumption, implementation of new alternatives in driving mills, the widespread practice of high steam parameters use in cogeneration facilities, the insertion of new technologies for biofuels production (hydrolysis and gasification), the energy conversion of sugarcane trash and vinasse, animal feed production, process integration and implementation of the biorefinery concept are considered. Another new paradigm consists in the wide spreading of sustainability studies of products and processes using the Life Cycle Assessment (LCA) and the implementation of sustainability indexes. Every approach to this issue has as an objective to increase the economic efficiency and the possibilities of the sugarcane as a main source of two basic raw materials: fibres and sugar. The paper briefly presents the concepts, indicators, state-of-the-art and perspectives of each of the referred issues.

scholarly journals Cryogenic technologies in biology and medicine

2020 ◽  
Vol 2020 (2b) ◽  
pp. 129-134
Author(s):  
O.I. Ossetsky ◽  
◽  
O.S. Snurnikov ◽  
Keyword(s):  
Public Health ◽  
Food Industry ◽  
Raw Materials ◽  
Biologically Active ◽  
Whole Body ◽  
Active Ingredients ◽  
Lipid Fractions ◽  
The World ◽  
New Generation

Cryogenic technologies in biology and medicine Current tendencies of the development of cryogenic technologies in the world practice and in Ukraine have been comparatively analyzed. A special attention has been paid to cryotechnologies in biology and medicine. The features of deriving the biologically active ingredients of natural raw materials by means of cryosublimation fractionation and extraction of lipid fractions with liquefied refrigerants, as well as perspectives of their application when obtaining the products of new generation in pharmacy, cosmetics, food industry have been considered. There were discussed the possibilities of human whole body extreme cryotherapy. Main aspects of its usage in practical public health have been considered.

scholarly journals Food fortification – a modern principle of the food industry

2020 ◽  
Vol 12 ◽  
pp. 70-76
Author(s):  
V.G. Kaishev ◽  
Keyword(s):  
Raw Materials ◽  
Caloric Intake ◽  
Food Products ◽  
Technical Literature ◽  
Short Supply ◽  
Mass Consumption ◽  
Organoleptic Characteristics ◽  
Physiological Properties ◽  
Physico Chemical ◽  
New Generation

Aim. To analyze the scientific and technical literature and identify ways to create a new generation of mass-consumption food products enriched with vital nutrients. Discussion. The main malnutrition of the Russian population is the excess of caloric intake over an indicator of the level of energy consumption. One of the ways to solve this problem is the production of functional food products or enriched functional products. The essence of this is that only those micronutrients that are really in short supply should be used in the fortification of products. These should be products of mass consumption, and especially those that undergo refining, which results in the loss of micronutrients. The use of raw materials and ingredients only of natural (animal, vegetable, mineral) origin, allows you to create active complexes that qualitatively change the physiological properties of the product, and can affect many product characteristics and processes such as physico-chemical, structural-mechanical and organoleptic characteristics of the product, the processes of color formation, fermentation, oxidation, storage capacity. However, sometimes a strong passion for enriching the product with useful macro- and micronutrients affects the taste characteristics. Conclusion. When developing recipes and technologies for new-generation products, it is necessary that the enrichment of the product with important and necessary elements does not worsen the organoleptic characteristics. At the same time, it is necessary to ensure the safety of products without compromising consumer properties. The diet should contain all the necessary nutrients (nutrients) for a person in sufficient quantities and balanced with each other in the most favorable proportions.

scholarly journals CHANGING OF PARADIGM IN MILITARY-POLITICAL THINKING IN THE DOCTRINES AND STRATEGIES OF MILITARY SECURITY OF UKRAINE OF THE 20th AND 21th CENTURIES

2021 ◽  
pp. 120-126
Author(s):  
Mykhailo Tsiurupa
Keyword(s):  
Security Policy ◽  
Military Strategy ◽  
New Paradigm ◽  
Political Thinking ◽  
Main Thesis ◽  
Political Response ◽  
Military Security ◽  
The Creation ◽  
New Generation ◽  
The Military

The time limits of the life of one generation are about 25-30 years, so lived in the struggle for building its own state and its armed defence, this time for Ukraine goes down in the history of the first generation of creation and attempts to comply with four military doctrines (1993-2004-2012-2015), in which our own defence course was proclaimed. The theoretical basis of these official documents of significance were certain paradigms of military-political thinking, according to which Ukraine did not consider it a continuation of politics. The direction and principles of military policy (defence or security policy in European terminology) for modern Ukraine from the mid-20s of the XIX century, as well as 100 years ago, again came to the fore in connection with the implementation of previously abstract concepts " annexation "," occupation "," war ", which allegedly did not exist for our country in recent history. But today they have been embodied or, in the image of Franz Kafka, "reincarnated" into threatening forms of Russia's military practice against our state, the end of which is not yet visible in the near future. The military-theoretical and political response was the "Military Strategy of Ukraine" in 2021, which "opened" a new generation of paradigms of militarypolitical thinking. The main thesis is the belief that the protection of sovereignty and strengthening of military security is the military-theoretical and political response was the "Military Strategy of Ukraine" in 2021, which "opened" a new generation of paradigms of military-political thinking. The main thesis is the belief that the protection of sovereignty and strengthening of military security is the creation of a "comprehensive defence system" with the integration of all forces of the state and civil society, law enforcement agencies and volunteers, administrative regions and territorial communities. The military-theoretical and political response was the "Military Strategy of Ukraine" in 2021, which "opened" a new generation of paradigms of military-political thinking. We will prove that this is a philosophy of military security instead of the previously expressed doctrinal military-political ideas of entrusting a matter of national importance to the forces of the defence sector. The new generation of public life Ukraine will begin with a new paradigm of militarypolitical thinking, the central idea of which is the transition from hopes for the political levers of defence for international cooperation to the creation of a system of comprehensive national security with the synergistic potential of Ukrainianity.

scholarly journals The Issues and Challenges Faced by Malay Cuisine in the Foreign Market

2021 ◽  
Vol 16 (2) ◽  
pp. 20-28
Author(s):  
Rahman Abdullah ◽  
Aniza Arifin ◽  
Azlina Samsudin ◽  
Sabaianah Bachok ◽  
Harnizam Zahari
Keyword(s):  
Cultural Heritage ◽  
Success Factors ◽  
Raw Materials ◽  
Country Of Origin ◽  
Foreign Market ◽  
Future Research ◽  
Traditional Food ◽  
Meal Preparation ◽  
New Generation

The traditional food of a culture in a society is continuously inherited from the old generation to the new generation. The traditional element is an in-depth understanding of the function of each material, techniques of preparation, and the practice in our daily cooking. This understanding in the form of preparation, meal preparation, tips, use of certain equipment, and raw materials are mysteries difficult to be unravelled. The Malay cultural heritage food is an integral asset among Malaysians in general and the Malay race in particular. Malay cuisine is one of the special and unique blended of many traditions from around the region. However, when Malay culture and cuisine are introduced to other countries, they faced certain hurdles and challenges. This study investigates the issues and challenges faced by Malay cuisine in the foreign market. The points in question are, 1) Why are Malay cuisine difficult to be exported to other countries 2) Why Malay cuisine is less popular than cuisines from other countries? 3) What are the factors that make foods from a country of origin can be successfully exported? These issues and challenges will be parsed and discussed based on the existing written collection. Recommendations will be made on the mechanisms that enable the success of Malay cuisine food to be commercialized abroad, as well as future research examining the success factors of traditional food exported abroad.  

Enrichment — the way to create a new generation of food products

2020 ◽  
pp. 36-40
Author(s):  
O.V. Sycheva ◽  
V.G. Kayshev
Keyword(s):  
Raw Materials ◽  
Caloric Intake ◽  
Food Products ◽  
Short Supply ◽  
Mass Consumption ◽  
Organoleptic Characteristics ◽  
Physiological Properties ◽  
Physico Chemical ◽  
New Generation ◽  
And Storage

The main dysnutrition of the Russian population is the excess of caloric intake over an indicator of the energy consumption level. One of the ways to solve this problem is the production of functional food products or enriched functional products. The essence of this is that only those micronutrients that are really in short supply should be used in the fortification of products. These should be products of mass consumption, and especially those that undergo refining, which results in the loss of micronutrients. The use of raw materials and ingredients only of natural (animal, vegetable, mineral) origin allows creating active complexes that qualitatively alter the physiological properties of the product and can affect many product characteristics and processes such as physico-chemical, structural, mechanical and organoleptic characteristics of the product, the processes of color formation, fermentation, oxidation, and storage capacity. However, sometimes a strong passion for enriching the product with useful macro- and micronutrients affects the taste characteristics. Therefore, when developing recipes and technologies for new-generation products, it is crucial that the enrichment of the product with important and necessary elements should not deteriorate the organoleptic characteristics. At the same time, it is essential to ensure the safety of products without compromising consumer properties. The diet should contain all the nutrients necessary for a person in sufficient quantities and balanced with each other in the most favorable proportions

Development of the New Generation Materials for the Soft Pipe Lining Rehabilitation

2005 ◽  
Author(s):  
Hsin Her Yu ◽  
Min-Hsun Cheng ◽  
Rong-Yuan Jou ◽  
Kuang-Chyi Lee ◽  
Chien-Chang Lin
Keyword(s):  
Mechanical Properties ◽  
Epoxy Resins ◽  
Potable Water ◽  
Raw Materials ◽  
Trade Mark ◽  
Power Cables ◽  
Different Types ◽  
Materials Used ◽  
New Generation ◽  
Optimum Sample

With increasing global urbanization and industrialization, many more pipelines for gas, potable water, sewer, oil, and power cables have been installed underground, underwater, in buildings and in factories. Maintenance of such pipelines is crucial. However, it is often difficult and has become a growing problem these days. The PALTEM-HL (Trade mark and stands for Pipeline Automatic Lining SysTEM, Hose Lining Method), a pipeline relining system, was developed as an effective and inexpensive solution for this problem. In this project, we try to develop a new resins and the adhesives system to replace the raw materials used in the PALTEM-HL system. Anionic harder combined two different types of epoxy resins were investigated in this study. After curing, the mechanical properties and glass transition temperature of the mixture were examined and the optimum sample preparation prescription was also found. FTIR (Fourier Transform Infrared Spectroscopy) and DSC (Differential Scanning Calorimeter) were employed to monitor the curing process of the mixtures. The mechanical properties of the mixture were also measured by Instron and micro Vickers.

Self-assembly of strawberry-like organic–inorganic hybrid particle clusters with directionally distributed bimetal and facile transformation of the core and corona

2020 ◽  
Vol 11 (18) ◽  
pp. 3136-3151 ◽  
Author(s):  
Shuxing Mei ◽  
Mingwang Pan ◽  
Juan Wang ◽  
Xiaopeng Zhang ◽  
Shaofeng Song ◽  
...  
Keyword(s):  
Strong Interaction ◽  
Self Assembly ◽  
Carboxyl Groups ◽  
Amino Groups ◽  
Inorganic Hybrid ◽  
Inorganic Particles ◽  
Hybrid Particle ◽  
The Core ◽  
Organic Particles ◽  
Facile Transformation

Controllable structure of organic–inorganic hybrid particle clusters were successfully fabricated by self-assembly which derived from the strong interaction between carboxyl groups of the organic particles and amino groups of the inorganic particles.

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