scholarly journals Silica Nanochannel Array Film Supported by ß-Cyclodextrin-Functionalized Graphene Modified Gold Film Electrode for Sensitive and Direct Electroanalysis of Acetaminophen

2022 ◽  
Vol 9 ◽  
Author(s):  
Huaxu Zhou ◽  
Yao Ding ◽  
Ruobing Su ◽  
Dongming Lu ◽  
Hongliang Tang ◽  
...  
Keyword(s):  
Self Assembly ◽  
Electrochemical Sensors ◽  
Limit Of Detection ◽  
Direct Analysis ◽  
Sensitive Detection ◽  
Film Electrode ◽  
Assembly Method ◽  
Surface Hydroxyls ◽  
Highly Sensitive Detection ◽  
Nanochannel Array

Convenient and sensitive detection of active analytes in complex matrix is crucial in biological, medical, and environmental analysis. Silica nanochannel array film (SNF) equipped electrochemical sensors have shown excellent anti-fouling performance in direct analysis of complex samples. In this work, we demonstrated an electrochemical sensor with anti-fouling performance for highly sensitive detection of acetaminophen (APAP) based on SNF supported by ß-cyclodextrin-graphene (CDG) nanocomposite modified Au film electrode (AuF). Because of their rich surface hydroxyls and 2D lamellar structure, CDG on AuF can serve as the nanoadhesive for compact binding SNF, which can be grown by electrochemical assisted self-assembly method in a few seconds. Attributable to the electrocatalytic property of graphene and the synergistic enrichment from both CD and SNF nanochannels towards analyte, the SNF/CDG/AuF sensor demonstrates sensitive detection of acetaminophen ranged from 0.2 to 50 μM with an ultralow limit-of-detection of 14 nM. Taking advantage of the anti-fouling ability of SNF, the sensor is able to realize accurate and convenient analysis of APAP in commercially available paracetamol tablets.

Dye encapsulated zinc-based metal-organic framework as a dual-emission sensor for highly sensitive detection of antibiotics

2021 ◽  
Author(s):  
Kang Wang ◽  
Yuhan Duan ◽  
Jiajing Chen ◽  
Haiying Wang ◽  
Hui-Yan Liu
Keyword(s):  
Self Assembly ◽  
Metal Organic Framework ◽  
Sensitive Detection ◽  
Dual Emission ◽  
Highly Sensitive ◽  
Metal Organic ◽  
Highly Sensitive Detection ◽  
Organic Framework

Self-assembly of two Zn-MOFs, [Zn2L(DMF)3]•H2O•5DMF (1) and [Zn2L(H2O)2]•4H2O•3DMF (2) were achieved with an amide-functionalized tetracarboxylate ligand under similar conditions. Incorporated amide groups make the tetratopic linkers exhibit different configurations, tetrahedron...

A supramolecular nanobiological hybrid as a PET sensor for bacterial DNA isolated from Streptomyces sanglieri

The Analyst ◽  
2014 ◽  
Vol 139 (24) ◽  
pp. 6502-6510 ◽  
Author(s):  
Sudesna Chakravarty ◽  
Dilip Saikia ◽  
Priyanka Sharma ◽  
Nirab Chandra Adhikary ◽  
Debajit Thakur ◽  
...  
Keyword(s):  
Limit Of Detection ◽  
Sensitive Detection ◽  
Bacterial Dna ◽  
Turn On ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

A ‘turn on–off–on’ sensor for highly sensitive detection of ds DNA with an excellent ‘limit of detection’ is reported.

In situ formation of SERS hot spots by a bis-quaternized perylene dye: a simple strategy for highly sensitive detection of heparin over a wide concentration range

The Analyst ◽  
2018 ◽  
Vol 143 (8) ◽  
pp. 1899-1905 ◽  
Author(s):  
Wei Ji ◽  
Xue Zhang ◽  
Jianzhang Zhao ◽  
Ye Gao ◽  
Wei Song ◽  
...  
Keyword(s):  
Hot Spots ◽  
Hot Spot ◽  
Sensitive Detection ◽  
Simple Strategy ◽  
Assembly Method ◽  
Highly Sensitive ◽  
In Situ Formation ◽  
Perylene Dye ◽  
Highly Sensitive Detection

We have demonstrated a simple SERS assay for the sensitive detection of heparin by means of an in situ hot spot assembly method.

scholarly journals A rapid and highly sensitive biomarker detection platform based on a temperature-responsive liposome-linked immunosorbent assay

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Runkai Hu ◽  
Keitaro Sou ◽  
Shinji Takeoka
Keyword(s):  
Immunosorbent Assay ◽  
Limit Of Detection ◽  
Specific Antigen ◽  
Fluorescence Emission ◽  
Detection Sensitivity ◽  
Sensitive Detection ◽  
Enzyme Linked Immunosorbent Assay ◽  
Temperature Responsive ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

Abstract The enzyme-linked immunosorbent assay (ELISA) is widely used in various fields to detect specific biomarkers. However, ELISA tests have limited detection sensitivity (≥ 1 pM), which is insufficiently sensitive for the detection of small amounts of biomarkers in the early stages of disease or infection. Herein, a method for the rapid and highly sensitive detection of specific antigens, using temperature-responsive liposomes (TLip) containing a squaraine dye that exhibits fluorescence at the phase transition temperature of the liposomes, was developed. A proof-of-concept study using biotinylated TLip and a streptavidin-immobilized microwell plate showed that the TLip bound to the plate via specific molecular recognition could be distinguished from unbound TLip within 1 min because of the difference in the heating time required for the fluorescence emission of TLip. This system could be used to detect prostate specific antigen (PSA) based on a sandwich immunosorbent assay using detection and capture antibodies, in which the limit of detection was as low as 27.6 ag/mL in a 100-μL PSA solution, 0.97 aM in terms of molar concentration. The present temperature-responsive liposome-linked immunosorbent assay provides an advanced platform for the rapid and highly sensitive detection of biomarkers for use in diagnosis and biological inspections.

MicroRNA-induced cascaded and catalytic self-assembly of DNA nanostructures for enzyme-free and sensitive fluorescence detection of microRNA from tumor cells

2016 ◽  
Vol 52 (12) ◽  
pp. 2501-2504 ◽  
Author(s):  
Xue Gong ◽  
Wenjiao Zhou ◽  
Yaqin Chai ◽  
Ruo Yuan ◽  
Yun Xiang
Keyword(s):  
Tumor Cells ◽  
Fluorescence Detection ◽  
Self Assembly ◽  
Signal Amplification ◽  
Sensitive Detection ◽  
Dna Nanostructures ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

MicroRNA-induced self-assembly formation of DNA nanostructures serves as a significant signal amplification platform for the highly sensitive detection of microRNA biomarkers.

scholarly journals Preparation and characterization of AuNPs/CNTs-ErGO electrochemical sensors for highly sensitive detection of hydrazine

Talanta ◽  
2016 ◽  
Vol 158 ◽  
pp. 283-291 ◽  
Author(s):  
Zhenting Zhao ◽  
Yongjiao Sun ◽  
Pengwei Li ◽  
Wendong Zhang ◽  
Kun Lian ◽  
...  
Keyword(s):  
Electrochemical Sensors ◽  
Sensitive Detection ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

scholarly journals Aptamer Embedded Arch-Cruciform DNA Assemblies on 2-D VS2 Scaffolds for Sensitive Detection of Breast Cancer Cells

Biosensors ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. 378
Author(s):  
Jinfeng Quan ◽  
Yihan Wang ◽  
Jialei Zhang ◽  
Kejing Huang ◽  
Xuemei Wang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Dna Sequences ◽  
Breast Cancer Cells ◽  
Limit Of Detection ◽  
Sensitive Detection ◽  
Highly Sensitive ◽  
Highly Sensitive Detection ◽  
Cruciform Dna ◽  
Mcf 7

Arch-cruciform DNA are self-assembled on AuNPs/VS2 scaffold as a highly sensitive and selective electrochemical biosensor for michigan cancer foundation-7 (MCF-7) breast cancer cells. In the construction, arch DNA is formed using two single-strand DNA sequences embedded with the aptamer for MCF-7 cells. In the absence of MCF-7 cells, a cruciform DNA labeled with three terminal biotin is bound to the top of arch DNA, which further combines with streptavidin-labeled horseradish peroxidase (HRP) to catalyze the hydroquinone-H2O2 reaction on the electrode surface. The presence of MCF-7 cells can release the cruciform DNA and reduce the amount of immobilized HRP, thus effectively inhibiting enzyme-mediated electrocatalysis. The electrochemical response of the sensor is negatively correlated with the concentration of MCF-7 cells, with a linear range of 10 − 1 × 105 cells/mL, and a limit of detection as low as 5 cells/mL (S/N = 3). Through two-dimensional materials and enzyme-based dual signal amplification, this biosensor may pave new ways for the highly sensitive detection of tumor cells in real samples.

CHAPTER 9. Nanomaterial-Based Electrochemical Sensors for Highly Sensitive Detection of Foodborne Pathogens

2016 ◽  
pp. 203-225
Author(s):  
Sukunya Oaew ◽  
Benchaporn Lertanantawong ◽  
Patsamon Rijiravanich ◽  
Mithran Somasundrum ◽  
Werasak Surareungchai
Keyword(s):  
Foodborne Pathogens ◽  
Electrochemical Sensors ◽  
Sensitive Detection ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

Highly sensitive detection of nitrite by using gold nanoparticle-decorated α-Fe2O3 nanorod arrays as self-supporting photo-electrodes

2019 ◽  
Vol 6 (6) ◽  
pp. 1432-1441 ◽  
Author(s):  
Shenghong Kang ◽  
Haimin Zhang ◽  
Guozhong Wang ◽  
Yunxia Zhang ◽  
Huijun Zhao ◽  
...  
Keyword(s):  
Gold Nanoparticle ◽  
Limit Of Detection ◽  
High Sensitivity ◽  
Sensitive Detection ◽  
Nanorod Arrays ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

Gold nanoparticle (Au NP)-decorated-Fe2O3 nanorod arrays (AuNPs-Fe2O3) as a photoelectrode are applied to the detection of nitrite solution with a low limit of detection and high sensitivity.

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