scholarly journals An Overview of Hypoglycemia in Children Including a Comprehensive Practical Diagnostic Flowchart for Clinical Use

2021 ◽  
Vol 12 ◽  
Author(s):  
Alberto Casertano ◽  
Alessandro Rossi ◽  
Simona Fecarotta ◽  
Francesco Maria Rosanio ◽  
Cristina Moracas ◽  
...  
Keyword(s):  
Neurological Complications ◽  
Clinical Use ◽  
Pediatric Age ◽  
Therapeutic Approaches ◽  
Age Related ◽  
Diagnostic Flowchart ◽  
Diagnostic Work ◽  
Work Up ◽  
Diagnostic Work Up

Hypoglycemia is the result of defects/impairment in glucose homeostasis. The main etiological causes are metabolic and/or endocrine and/or other congenital disorders. Despite hypoglycemia is one of the most common emergencies in neonatal age and childhood, no consensus on the definition and diagnostic work-up exists yet. Aims of this review are to present the current age-related definitions of hypoglycemia in neonatal-pediatric age, to offer a concise and practical overview of its main causes and management and to discuss the current diagnostic-therapeutic approaches. Since a systematic and prompt approach to diagnosis and therapy is essential to prevent hypoglycemic brain injury and long-term neurological complications in children, a comprehensive diagnostic flowchart is also proposed.

scholarly journals Age-related aspects of differential diagnosis of acute cough in children and adults

2018 ◽  
Vol 28 (4) ◽  
pp. 461-468
Author(s):  
I. V. Leshchenko ◽  
S. A. Tsar’kova ◽  
A. D. Zherebtsov
Keyword(s):  
Differential Diagnosis ◽  
Anatomical Location ◽  
Pathological Changes ◽  
Review Of Literature ◽  
Acute Cough ◽  
Age Related ◽  
Common Causes ◽  
Diagnostic Work ◽  
Work Up ◽  
Diagnostic Work Up

Cough is one of the most common causes of seeking the primary medical care, especially during the autumn and the spring. This article is a review of literature  aimed at differential diagnosis of possible causes of acute cough in children and  adults. Given a vast majority of diseases associated with cough, differential diagnosis  have to consider several issues. The key issue is cough duration and possible  anatomical location of the pathological changes. An algorithm of differential diagnosis  of acute cough in children and adults and description of most common diseases  associated with acute cough are given in the review. Further diagnostic work-up  should be driven by the duration of cough as soon as the acute cough could be first  manifestation of a chronic disease.

Urethral Diverticulum in Women with Neurologic Bladder

1998 ◽  
Vol 65 (4) ◽  
pp. 532-535
Author(s):  
P. Menchinelli ◽  
L De Giovanni ◽  
A. Manca ◽  
J.M. Weir ◽  
G. Ronzoni
Keyword(s):  
Multiple Sclerosis ◽  
Urethral Diverticulum ◽  
Therapeutic Strategies ◽  
Long Term Results ◽  
White Population ◽  
Diagnostic Work ◽  
Work Up ◽  
Female Urethral Diverticulum ◽  
Diagnostic Work Up

Female urethral diverticulum is a rather rare pathology, often ignored, which affects from 1 to 4% of the white population. In this study we report our series, limited to a selected population of women affected by neurologic bladder (6 paraplegic patients; 2 patients with multiple sclerosis) who were referred to our Urosurgical Unit within the space of four years. The diagnostic work-up relevant to these patients is discussed, together with the therapeutic strategies carried out and the long-term results obtained.

The Japanese Operation for Biliary Atresia: Remedy or Mischief?

PEDIATRICS ◽  
1975 ◽  
Vol 55 (1) ◽  
pp. 12-19
Author(s):  
John R. Lilly
Keyword(s):  
Biliary Atresia ◽  
Case Illustration ◽  
Kasai Operation ◽  
Early Results ◽  
Bile Drainage ◽  
Diagnostic Work ◽  
Work Up ◽  
Term Analysis ◽  
Diagnostic Work Up

A case illustration is given of an infant with biliary atresia who had the Kasai operation more than 1½ years ago and is now, by all biochemical and histiological criteria, cured. The early results with this operation in 14 patients are similar to those reported by the Japanese, that is, 25% have had sustained postoperative bile drainage. Success has never been achieved in infants older than 4 months. A long-held notion in this country to withhold operation in infants with jaundice until after 4 months has thus far militated against a critical and impartial evaluation of the Kasai operation. A plea is made to complete diagnostic work-up for jaundice during the first months of life so that the operation, if elected, may have a genuine chance for legitimate long-term analysis.

scholarly journals Cannabinoid Hyperemesis Syndrome: The Missed Diagnosis

2020 ◽  
Vol 6 (3) ◽  
pp. 127-130
Author(s):  
João B. Fonseca ◽  
Daniela Vilaverde ◽  
Rosa Rodrigues ◽  
Pedro Morgado
Keyword(s):  
Illicit Drug ◽  
Cannabis User ◽  
Cannabinoid Hyperemesis Syndrome ◽  
History Of ◽  
Missed Diagnosis ◽  
Diagnostic Work ◽  
Work Up ◽  
Diagnostic Work Up ◽  
Cyclic Vomiting

Cannabis is the most cultivated and abused illicit drug worldwide. Paradoxically to the antiemetic properties attributed to cannabis, a relatively new cannabinoid hyperemesis syndrome (CHS) started to be recognized and is characterized by cyclic vomiting that are interspaced by asymptomatic phases. We present a case of a 36‑year‑old woman who repeatedly presented to the emergency room with cyclic vomiting that alleviated with hot showers. She was a long‑term cannabis user and the diagnosis was only established several years later after the onset of symptoms. The diagnostic work up was unremarkable, and the only effective treatment was cannabis cessation. Hot bathing behavior is a key characteristic of this syndrome. CHS is a new clinical condition that should be considered in a setting of recurrent and intractable vomiting in patients with a history of cannabis use.

Diagnosis and management of urethro-cavernosal fistulas

2020 ◽  
Vol 13 (6) ◽  
pp. 398-401
Author(s):  
Jullet Han ◽  
Saum Ghodoussipour ◽  
Evgeniy I Kreydin ◽  
Leo Doumanian
Keyword(s):  
Case Reports ◽  
Case Series ◽  
Surgical Approaches ◽  
Success Rates ◽  
Long Term Outcomes ◽  
Level Of Evidence ◽  
Diagnostic Work ◽  
Work Up ◽  
Diagnostic Work Up

Objective: To present a case series of urethro-cavernosal fistulas evaluating their diagnostic work-up and management. Methods: A literature search was performed using key words including “urethro-cavernosal fistula,” “urethral fistula,” and “cavernosal fistula.” Results: In total 10 case reports were identified and reviewed for information regarding clinical diagnosis, management, and long-term outcomes including success rates and complications. Conclusion: Urethro-cavernosal fistula is a rare urological condition. With few cases reported to date, there is considerable variation in diagnostic work-up and management. Both conservative and surgical approaches can be utilized in the management of urethro-cavernosal fistulas with good long-term outcomes. Level of evidence: Not applicable for this multicentre audit.

Anemia in children: prevalence, causes, diagnostic work-up, and long-term consequences

2017 ◽  
Vol 10 (11) ◽  
pp. 1023-1028 ◽  
Author(s):  
Slimane Allali ◽  
Valentine Brousse ◽  
Anne-Sylvia Sacri ◽  
Martin Chalumeau ◽  
Mariane de Montalembert
Keyword(s):  
Long Term Consequences ◽  
Diagnostic Work ◽  
Work Up ◽  
Diagnostic Work Up

scholarly journals Stroke masquerading as cardiac arrest: the artery of Percheron

2021 ◽  
Vol 14 (1) ◽  
pp. e238681
Author(s):  
Megan Quetsch ◽  
Sureshkumar Nagiah ◽  
Stephen Hedger
Keyword(s):  
Cardiac Arrest ◽  
Clinical Assessment ◽  
Altered Consciousness ◽  
Cognitive Changes ◽  
Consciousness Level ◽  
Artery Of Percheron ◽  
Conscious Level ◽  
Diagnostic Work ◽  
Work Up ◽  
Diagnostic Work Up

The artery of Percheron (AOP) is a rare arterial variant of the thalamic blood supply. Due to the densely packed collection of nuclei it supplies, an infarction of the AOP can be devastating. Here we highlight a patient who had an AOP stroke in the community, which was initially managed as cardiac arrest. AOP strokes most often present with vague symptoms such as reduced conscious level, cognitive changes and confusion without obvious focal neurology, and therefore are often missed at the initial clinical assessment. This case highlights the importance of recognising an AOP stroke as a cause of otherwise unexplained altered consciousness level and the use of MRI early in the diagnostic work-up.

scholarly journals Death of unknown cause? Post-mortem diagnosis of fulminant course of an EBV-associated secondary hemophagocytic lymphohistiocytosis

2021 ◽  
Author(s):  
Josia Fauser ◽  
Stefan Köck ◽  
Eberhard Gunsilius ◽  
Andreas Chott ◽  
Andreas Peer ◽  
...  
Keyword(s):  
Immune Response ◽  
Case Report ◽  
Macrophage Activation ◽  
Post Mortem ◽  
Life Threatening ◽  
Appropriate Therapy ◽  
Diagnostic Work ◽  
Work Up ◽  
Diagnostic Work Up ◽  
Secondary Hemophagocytic Lymphohistiocytosis

SummaryHLH is a life-threatening disease, which is characterized by a dysregulated immune response with uncontrolled T cell and macrophage activation. The often fulminant course of the disease needs a fast diagnostic work-up to initiate as soon as possible the appropriate therapy. We present herein the case of a 71-year-old patient with rapidly progressive hyperinflammatory syndrome, which post mortem resulted in the diagnosis of EBV-associated HLH. With this case report, we intend to highlight the relevance of the HScore in the diagnosis of HLH, to create a greater awareness for EBV as a trigger of HLH, and to demonstrate the importance of treating EBV-associated HLH as early as possible.

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