Suprasellar Mature Cystic Teratoma Mimicking Rathke’s Cleft Cyst: A Case Report and Systematic Review of the Literature

2021 ◽  
Vol 12 ◽  
Shenzhong Jiang ◽  
Zhaojian Wang ◽  
Yan You ◽  
Renzhi Wang ◽  
Xinjie Bao

In this article, we present a 31-year-old female who presented with intermittent headache and oligomenorrhea of over 10 years’ duration. Imaging revealed a large suprasellar mass with sellar extension. The patient underwent an endoscopic endonasal trans-sphenoidal surgery to resection of the mass. Clinical, radiological, and operative findings from this patient were initially considered to be Rathke’s cleft cyst (RCC). However, postoperative histological examinations revealed a mature cystic teratoma. No radiotherapy was performed after surgery. At the most recent follow-up, approximately 1 year later, the patient is doing well with no headache and no recurrence of the teratoma.

2001 ◽  
Vol 8 (6) ◽  
pp. 564-567 ◽  
Markus Wenger ◽  
Marian Simko ◽  
Regula Markwalder ◽  
Ethan Taub

2008 ◽  
Vol 44 (4) ◽  
pp. 256 ◽  
Choong-Hyun Lee ◽  
Eui-Kyo Seo ◽  
Yong-Jae Cho ◽  
Sang-Jin Kim

2021 ◽  
Emre Gezer ◽  
Burak Çabuk ◽  
Büşra Yaprak Bayrak ◽  
Zeynep Cantürk ◽  
Berrin Çetinarslan ◽  

Abstract PurposeHypophysitis (HP) is a rare disease which develops secondary to chronic or acute inflammation of the pituitary gland and may cause symptoms related to pituitary dysfunction and mass compression. Lymphocytic HP is the most common subtype of primary HP, while xanthomatous HP (XHP) is considered the rarest form, with 35 reported cases, to date. Case ReportA 35-year-old woman was initially admitted to a Gynecology clinic with a 2-year history of amenorrhea and headache. She was started on cabergoline 0.5 mg twice a week for macroprolactinoma. Due to persistent amenorrhea with low gonadotropins, she was referred to our Endocrinology clinic. Her pituitary function profile revealed panhypopituitarism and a 13 x 11 x 12 mm sized sellar mass with diffuse enhancement which sustained toward the infundibulum and dura was observed on the gadolinium-enhanced pituitary MRI. The patient underwent an endoscopic endonasal transsphenoidal approach for tumor resection and thick yellowish fluid draining from the lesion was observed. The histopathological diagnosis was reported as a rupture of an Rathke’s cleft cyst and a xanthomatous hypophysitis. The surgery did not improve the symptoms/pituitary functions, however, headache recovered immediately after the first dose of high dose methylprednisolone treatment. ConclusionThe inflammatory process in a xanthomatous lesion may actually be a secondary response to mucous fluid content release from a ruptured cyst, thus recommended to classify XHP as secondary hypophysitis. Since the differentiation of XHP from other pituitary tumors may be challenging preoperatively, surgery is the major diagnostic tool and also, the most recommended therapeutic option.

2002 ◽  
Vol 45 (1) ◽  
pp. 47-51 ◽  
A. Alfieri ◽  
R. Schettino ◽  
A. Tarfani ◽  
O. Bonzi ◽  
G. A. Rossi ◽  

2020 ◽  
Vol 133 ◽  
pp. 381-391.e2
Michel Roethlisberger ◽  
Ronie Romelean Jayapalan ◽  
Isabel Charlotte Hostettler ◽  
Khairul Azmi Bin Abd Kadir ◽  
Kein Seong Mun ◽  

2009 ◽  
Vol 95 (1) ◽  
pp. 104-107 ◽  
Metin Akbulut ◽  
Osman Zekioglu ◽  
Mustafa Cosan Terek ◽  
Necmettin Ozdemir

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