scholarly journals Systematic Review of Fatigue in Individuals With Cerebral Palsy

2021 ◽  
Vol 15 ◽  
Author(s):  
Luca Puce ◽  
Ilaria Pallecchi ◽  
Karim Chamari ◽  
Lucio Marinelli ◽  
Tiziano Innocenti ◽  
...  

In this systematic review, we collected and analyzed literature works comparing self-reported fatigue and objectively-measured fatigue in individuals with cerebral palsy (CP) and in age-matched typically developing/typically developed (TD) controls (Healthy). The search was conducted on four electronic databases/platforms (PubMed, Web of Science, Cochrane Library, and Scopus) using the key words “cerebral palsy” combined with “fatig*,” where the asterisk was used as a wildcard. As a critical appraisal tool, the Joanna Briggs Institute Critical Appraisal Checklist for Quasi-Experimental Studies (2017) was used. A total of 22 studies passed the critical appraisal rating and were included in both narrative and quantitative analyses. The overall evidence quality of the findings was considered very good. Data of objectively-measured fatigue in performing maximal fatiguing tasks indicated lower fatigue levels in participants with CP, possibly due to their pathological inability to recruit highly fatigable muscle fibers. Highly trained individuals with CP and TD controls performing maximal fatiguing tasks seem to be an exception to this, as they exhibited similar levels of fatigue. In submaximal fatiguing tasks, including daily physical activities, either objectively-measured or self-reported fatigue was higher in participants with CP than in TD controls, indicating a lower ability for development of neurophysiological compensation for fatigue among participants with CP. Further studies on fatigue are needed to gain an insight into the multifold mechanisms of fatigue in individuals with CP. Understanding fatigue mechanisms could help in setting up strategies for effective intervention programs, with benefits in healthcare and improved quality of life of individuals with CP.Systematic Review Registration: [PROSPERO 2019], identifier [CRD42019143524].

2022 ◽  
Vol 10 (1) ◽  
Author(s):  
Fatima Safi ◽  
Anna M. Aniserowicz ◽  
Heather Colquhoun ◽  
Jill Stier ◽  
Behdin Nowrouzi-Kia

Abstract Background Eating disorders (ED) can reduce quality of life by limiting participation and performance in social and occupational roles, including paid or unpaid work. The association between ED pathologies and work participation and performance must be well understood to strengthen vocational rehabilitation programmes and prevent occupational disruptions in the ED population. The aims of this study are: (1) to examine the degree of association between ED pathologies and work participation and performance in 15-year-olds and older; (2) to highlight the specific ED symptoms that are most correlated with changes in work performance and participation; (3) to compile the most common metrics and assessments used to measure work participation and performance with ED. Methods Medline, Embase, CINAHL, Web of Science, PsycINFO, and Cochrane Library will be searched for observational and experimental studies that meet the following criteria: (1) a clinical sample of typical or atypical ED; (2) paid or unpaid employment or training; (3) an association between ED pathologies and work participation or performance. Unpublished data will also be examined. Title and abstract, and full-text screening will be conducted in duplicate. Risk of bias and quality of evidence assessments will be completed. A random-effect meta-analysis will be performed. Discussion This synthesis can clarify knowledge and gaps around the impact of ED on work functioning, thereby allowing better evaluation, improvements and development of current workplace assessments, interventions, and policies. Trial registration The registration number for this systematic review on PROSPERO is CRD42021255055.


2021 ◽  
Vol 10 (1) ◽  
pp. 5-13
Author(s):  
Hafiza Javeria ◽  
Yusra Obaid ◽  
Ismail Naseem

BACKGROUND AND AIMS Cupping Therapy is an ancient form of alternative medicine for treating variety of musculoskeletal disorders. Number of studies indicated the efficacy of various cupping methods in decreasing neck or back pain intensity within short duration and improves quality of life. DATABASES AND ELIGIBILITY CRITERIA The experimental studies were searched on the electronic databases including Google Scholar, PEDro, PubMed and Cochrane Library from June 2015 to December 2019. It was ensured that all articles were full-text in English language whereas screening was executed on relevant titles and abstracts, evaluated on the basis of cupping therapy and its effects on musculoskeletal pain. RESULTS A total of eight out of ten experimental studies showed significant decrease (p<0.05) in spinal pain in result of cupping therapy except for the two studies that demonstrated no significant pre-post group differences (p>0.05).


10.2196/17899 ◽  
2020 ◽  
Vol 22 (12) ◽  
pp. e17899
Author(s):  
Kija Malale ◽  
Jili Fu ◽  
William Nelson ◽  
Helena Marco Gemuhay ◽  
Xiuni Gan ◽  
...  

Background In recent years, there have been many suggestions to use multimedia as a strategy to fully meet the educational needs of patients with peripherally inserted central catheters. However, the potential benefits remain unreliable in the literature. Objective In this study, we identified the potential benefits of multimedia-based home catheter management education in patients with peripherally inserted central catheters and discussed the clinical implications. Methods We performed systematic searches of the PubMed, Cochrane Library, Embase Ovid, Medline, BioMed Central-cancer (BMC-cancer), ScienceDirect, and Google Scholar databases without date constraints until November 30, 2019. The methodological quality of the eligible studies was appraised using the Cochrane risk of bias tool. Narrative synthesis of the study findings was conducted. Results A total of 6 intervention studies met the inclusion criteria, including 3 randomized controlled trials and 3 case-control studies/quasi-experimental studies. The studies included a total of 355 subjects, including a total of 175 in the multimedia groups and 180 in the control groups. We identified 4 potential benefits to patients: (1) improved knowledge, (2) increased satisfaction, (3) reduced incidence of catheter-related complications, and (4) reduced number of cases of delayed care after complications. Conclusions The current systematic review highlights the potential benefits of multimedia-based home catheter management education for patients with peripherally inserted central catheters.


Author(s):  
Tongyao Wang ◽  
Joachim G Voss

Abstract The objective of this review was to investigate process of pictograph development and the effectiveness of pictographs in patient education. We conducted searches in Medline/PubMed, CINAHL with full text, PsycInfo, ERIC and Cochrane Library with keywords: (pictograph or pictorial) AND (patient education) NOT (children or adolescent or youth or child or teenagers). After excluding manuscripts that did not meet inclusion criteria, 56 articles were included between the time of the last review on this topic (January 2008) and May 2019. There are 17 descriptive studies, 27 randomized control trial studies, 9 quasi-experimental studies and 2 unique literatures in the systematic review. Major goals of the studies are pictograph development or validation. The majority of manuscripts (n = 48) supported the approach. However, six studies did not find significant differences in the outcome. Differences in patient population, pictograph designs and author-developed outcome measurements made it difficult to compare the findings. There is a lack of evidence on validating information outcome measurements. This review demonstrated that implementing pictographs into patient education is a promising approach for better information understanding and health management. Pictographic interventions need to be carefully developed and validated with both the targeted patient population and the clinical experts.


2021 ◽  
Author(s):  
Izabela Zibetti Albuquerque ◽  
Lusmaia Damaceno Camargo Costa ◽  
Patrícia Marques Fortes ◽  
Guilherme Matos Abe ◽  
Paulo Sérgio Sucasas da Costa

Abstract Background: Cystic Fibrosis is a genetic disease characterized by a mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, responsible for encoding the protein that regulates the function of chlorine and sodium channels in the cell membrane. The bioactive compound curcumin has shown modulating and restorative effects on sodium, chlorine and water transport, and seems to be a candidate to act in the expression of the function of the chlorine channels. The purpose of this protocol is to demonstrate scientific evidence of molecular and clinical effects of curcumin in cell cultures, animals and subjects with cystic fibrosis.Methods: The search will be conducted in the following databases - MEDLINE/PubMed, SCOPUS, Cochrane Library and EMBASE. Reviewers will select original intervention (in vitro and in vivo) and/or observational articles that analyzed the effects of curcumin on cystic fibrosis. The methodological quality of the studies will be assessed by the Joana Briggs Institute's Checklist for Quasi-Experimental Studies. The GRADE tool will be applied to grade the quality of evidence.Discussion: To date, no systematic reviews have been published that assessed molecular and clinical effects of curcumin on cystic fibrosis. Upon completion of this systematic review, it is expected that the evidence found may contribute to the development of therapeutic formulations capable of modulating the function of the CFTR protein, restoring its properties, and contributing to the reduction of systemic clinical manifestations of cystic fibrosis.Systematic review registration: PROSPERO CRD42021229294


2019 ◽  
Vol 30 (1) ◽  
pp. 3-18 ◽  
Author(s):  
Martin Bergström ◽  
Marianne Cederblad ◽  
Kickan Håkansson ◽  
Ann Kristine Jonsson ◽  
Christian Munthe ◽  
...  

Objective: Foster family care is associated with adverse short- and long-term consequences for the child. A systematic review was conducted on interventions for foster children and foster careers. Method: A comprehensive search process was used to find eligible interventions evaluated in randomized controlled trials or quasi-experimental studies. The quality of studies was assessed with GRADE, and effects were synthesized using meta-analytic methods. Results: In all, 28 publications of 18 interventions, including 5,357 children, were identified. Only three specific interventions had sufficient confidence of evidence. No study had examined tools for foster parent selection nor had evaluated preservice programs related to outcomes. Discussion: These analyses provide new insights and hope into the field of systematic interventions in foster care. The overall results indicate that it is possible to improve eight outcomes but cannot point out which programs are superior. Ethically, social care organizations should systematically collect knowledge about effects and side effects.


BMJ Open ◽  
2017 ◽  
Vol 7 (9) ◽  
pp. e015924 ◽  
Author(s):  
Christine Mpundu-Kaambwa ◽  
Gang Chen ◽  
Elisabeth Huynh ◽  
Remo Russo ◽  
Julie Ratcliffe

IntroductionCerebral palsy is the most common cause of physical disability in children and adolescents and is associated with impairments that may reduce the quality of life (QOL) of this population. Patient-reported outcome measures (PROMs) can facilitate the assessment of the effect of disease and treatment on QOL, from a patient viewpoint. The purpose of this systematic review is to identify PROMs that are used to measure QOL and subjective well-being (SWB) outcomes in young people with cerebral palsy and to evaluate the suitability of these PROMs for application in economic evaluations within this population.Methods and analysisMEDLINE, Scopus, the Cochrane Library, Web of Science Core Collection, EconLit, PsycINFO, CINAHL, EMBASE and Informit will be systematically searched from inception to date of search. Published peer-reviewed, English-language articles reporting PROMs measuring QOL or SWB outcomes in children and adolescents with cerebral palsy will be included. One reviewer will conduct the initial search and screen titles and abstracts for potentially eligible studies. The search will be performed in November 2017. To reduce the likelihood of reviewer selection bias, two other reviewers will independently screen a randomly selected subsample (10%) of the citations. Two reviewers will then retrieve full texts of potentially eligible studies and assess them against predefined inclusion criteria. The suitability of selected PROMs for use in economic evaluations of young people with cerebral palsy will be assessed using the International Society of Quality of Life Research recommended Minimum Standards and the Patient-Centered Outcomes and Comparative Effectiveness Research checklist. A narrative synthesis of extracted data will be presented including study descriptive data, PROMs measurement properties, settings in which they were applied and the valuation methods. Recommendations for practice on the selection of PROMs for use in economic evaluations of children and adolescents with cerebral palsy will be presented.Ethics and disseminationEthical approval is not required as the proposed systematic review will not use primary data. The results of this study will be widely disseminated through publication in a peer-reviewed journal and conference presentation(s).Systematic review registration numberInternational Prospective Register of Systematic Reviews number: CRD42016049746.


2017 ◽  
Vol 30 (suppl 1) ◽  
pp. 373-382 ◽  
Author(s):  
Ricardo Rodrigues de Sousa Junior ◽  
Priscila de Lima ◽  
Josiele Neves da Silva ◽  
Daniela Virgínia Vaz

Abstract Introduction: Cerebral Palsy is a group of non-progressive movement and posture disorders. There are many rehabilitation methods for children and adolescents with these disorders. Kinesiology Taping(KT) is becoming a popular as an option of rehabilitation method for these children. Objective: The aim of this systematic review is to summarize evidence regarding the methods of Kinesiology Taping use in children and adolescents with Cerebral Palsy and its effects. Materials: A search of scientific papers in the databases Medline, Scielo and PEDro was conducted with no data or language restriction. For this search the keywords “Kinesio taping”, “Kinesiology Taping”, “Taping”, and “Bandages” combined with “Cerebral Palsy” were used. The search was conducted between May of 2015 and November of 2016. Results: Eleven studies were included in the review, six were randomized controlled clinical trials, four were quasi-experimental studies, and one was a case study. In general, the studies followed the guidelines proposed by the Kinesiology Taping creator; they used corrective techniques and muscle contraction facilitation/inhibition techniques. Results varied according to techniques used and outcomes chosen. Conclusion: There is strong to insufficient evidence of KT effects in motor function related outcomes. Stronger quality level studies are necessary to support use of KT in clinical practice.


Lupus ◽  
2021 ◽  
pp. 096120332110050
Author(s):  
Angela Chang ◽  
Nathan W Winquist ◽  
Annie B Wescott ◽  
Emily G Lattie ◽  
Andrea K Graham

Background Patients with systemic lupus erythematous (SLE) experience psychological comorbidities and impaired quality of life (QOL). We conducted a systematic review to examine the efficacy of non-pharmacological interventions for improving psychological outcomes and/or QOL in patients with SLE. To expand on a previous systematic review in this area and enhance our understanding of efficacious interventions for this population, our search included quasi-experimental and experimental studies of interventions delivered or supported by remote methods (including digitally) or in person. Methods A comprehensive literature search was conducted with a research librarian using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and was registered before data extraction on the international prospective register of systematic reviews PROSPERO Web site (CRD42020154962). The search included controlled-vocabulary and title/abstract terms related to non-pharmacological interventions for SLE published through October 2019 in MEDLINE (Ovid), Cochrane Library databases (Wiley), Embase (Elsevier), CINAHL (EBSCO), PsycINFO (EBSCO), Web of Science (Clarivate), ACM Digital (Association of Computer Machinery), and IEEE Xplore. Studies were synthesized using a systematic narrative synthesis framework. Risk of bias was assessed. Studies were synthesized using a systematic narrative synthesis framework. Risk of bias was assessed. Results Twenty-three studies were included: 21 randomized controlled trials and two quasi-experimental studies. Non-pharmacological diet, physical activity, psychological, and course-based interventions improved QOL and psychological outcomes, and were delivered in traditional settings (e.g., hospital) or remotely. No studies assessing digital non-pharmacological interventions were identified in our search. Quality assessments showed serious risk of bias for the two quasi-experimental studies, and high risk of bias in a subset of experimental studies. Conclusions Non-pharmacological interventions benefit patients with SLE. Future research should include more representative samples in rigorous evaluations and consider ways to incorporate digital technologies to increase accessibility.


2020 ◽  
Author(s):  
Kija Malale ◽  
Jili Fu ◽  
William Nelson ◽  
Helena Marco Gemuhay ◽  
Xiuni Gan ◽  
...  

BACKGROUND In recent years, there have been many suggestions to use multimedia as a strategy to fully meet the educational needs of patients with peripherally inserted central catheters. However, the potential benefits remain unreliable in the literature. OBJECTIVE In this study, we identified the potential benefits of multimedia-based home catheter management education in patients with peripherally inserted central catheters and discussed the clinical implications. METHODS We performed systematic searches of the PubMed, Cochrane Library, Embase Ovid, Medline, BioMed Central-cancer (BMC-cancer), ScienceDirect, and Google Scholar databases without date constraints until November 30, 2019. The methodological quality of the eligible studies was appraised using the Cochrane risk of bias tool. Narrative synthesis of the study findings was conducted. RESULTS A total of 6 intervention studies met the inclusion criteria, including 3 randomized controlled trials and 3 case-control studies/quasi-experimental studies. The studies included a total of 355 subjects, including a total of 175 in the multimedia groups and 180 in the control groups. We identified 4 potential benefits to patients: (1) improved knowledge, (2) increased satisfaction, (3) reduced incidence of catheter-related complications, and (4) reduced number of cases of delayed care after complications. CONCLUSIONS The current systematic review highlights the potential benefits of multimedia-based home catheter management education for patients with peripherally inserted central catheters.


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