scholarly journals Multisensory Integration: Is Medial Prefrontal Cortex Signaling Relevant for the Treatment of Higher-Order Visual Dysfunctions?

2022 ◽  
Vol 14 ◽  
Author(s):  
Miguel Skirzewski ◽  
Stéphane Molotchnikoff ◽  
Luis F. Hernandez ◽  
José Fernando Maya-Vetencourt
Keyword(s):  
Prefrontal Cortex ◽  
Information Processing ◽  
Medial Prefrontal Cortex ◽  
Multisensory Integration ◽  
Environmental Enrichment ◽  
Higher Order ◽  
Mammalian Brain ◽  
Non Invasive ◽  
Sensory Modalities ◽  
Cerebral Visual Impairment

In the mammalian brain, information processing in sensory modalities and global mechanisms of multisensory integration facilitate perception. Emerging experimental evidence suggests that the contribution of multisensory integration to sensory perception is far more complex than previously expected. Here we revise how associative areas such as the prefrontal cortex, which receive and integrate inputs from diverse sensory modalities, can affect information processing in unisensory systems via processes of down-stream signaling. We focus our attention on the influence of the medial prefrontal cortex on the processing of information in the visual system and whether this phenomenon can be clinically used to treat higher-order visual dysfunctions. We propose that non-invasive and multisensory stimulation strategies such as environmental enrichment and/or attention-related tasks could be of clinical relevance to fight cerebral visual impairment.

Unimodal experience constrains while multisensory experiences enrich cognitive construction

2008 ◽  
Vol 31 (3) ◽  
pp. 335-336 ◽  
Author(s):  
Andrew J. Bremner ◽  
Charles Spence
Keyword(s):  
Information Processing ◽  
Multisensory Integration ◽  
Developmental Constraints ◽  
Sensory Modalities

AbstractMareschal and his colleagues argue that cognition consists of partial representations emerging from organismic constraints placed on information processing through development. However, any notion of constraints must consider multiple sensory modalities, and their gradual integration across development. Multisensory integration constitutes one important way in which developmental constraints may lead to enriched representations that serve more than immediate behavioural goals.

Toward a Computational Understanding of Neuroaesthetics

2021 ◽  
pp. 127-131
Author(s):  
Kiyohito Iigaya ◽  
John P. O’Doherty
Keyword(s):  
Prefrontal Cortex ◽  
Visual Cortex ◽  
Medial Prefrontal Cortex ◽  
Visual Stimulus ◽  
Higher Order ◽  
Aesthetic Judgment ◽  
Statistical Properties ◽  
Association Cortex ◽  
Aesthetic Value ◽  
The Brain

Among the most challenging questions in the field of neuroaesthetics concerns how a piece of art comes to be liked in the first place. That is, how can the brain rapidly process a stimulus to form an aesthetic judgment even for stimuli never before encountered? In the article under discussion in this chapter, by leveraging computational methods in combination with behavioral and neuroimaging experiments the authors show that the brain does this by breaking a visual stimulus down into underlying features or attributes. These features are shared across objects, and weights over these features are integrated over to produce aesthetic judgments. This process is structured hierarchically in which elementary statistical properties of an image are combined to generate higher level features which in turn yield aesthetic value. Neuroimaging supports the implementation of this hierarchical integration along a gradient from early to higher order visual cortex extending into association cortex and ultimately converging in the anterior medial prefrontal cortex.

Effects of environmental enrichment on behavior and dopamine transporter function in medial prefrontal cortex in adult rats prenatally treated with cocaine

2004 ◽  
Vol 153 (2) ◽  
pp. 213-223 ◽  
Author(s):  
Nichole M. Neugebauer ◽  
S. Tiffany Cunningham ◽  
Jun Zhu ◽  
Rachel I. Bryant ◽  
Lisa S. Middleton ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Dopamine Transporter ◽  
Medial Prefrontal Cortex ◽  
Environmental Enrichment ◽  
Adult Rats

Malfunctional Reorganization in the Developing Limbo-Prefrontal System in Animals: Implications for Human Psychoses?

2001 ◽  
Vol 12 (1) ◽  
pp. 8-14
Author(s):  
Gertraud Teuchert-Noodt ◽  
Ralf R. Dawirs
Keyword(s):  
Prefrontal Cortex ◽  
Mental Disorders ◽  
Dentate Gyrus ◽  
Cognitive Functions ◽  
Experimental Approach ◽  
Regulatory Mechanisms ◽  
Hippocampal Dentate Gyrus ◽  
Non Invasive ◽  
Invasive Method ◽  
Activity Dependent

Abstract: Neuroplasticity research in connection with mental disorders has recently bridged the gap between basic neurobiology and applied neuropsychology. A non-invasive method in the gerbil (Meriones unguiculus) - the restricted versus enriched breading and the systemically applied single methamphetamine dose - offers an experimental approach to investigate psychoses. Acts of intervening affirm an activity dependent malfunctional reorganization in the prefrontal cortex and in the hippocampal dentate gyrus and reveal the dopamine position as being critical for the disruption of interactions between the areas concerned. From the extent of plasticity effects the probability and risk of psycho-cognitive development may be derived. Advance may be expected from insights into regulatory mechanisms of neurogenesis in the hippocampal dentate gyrus which is obviously to meet the necessary requirements to promote psycho-cognitive functions/malfunctions via the limbo-prefrontal circuit.

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