scholarly journals Supply Chain and Delivery of Antimicrobial Drugs in Smallholder Livestock Production Systems in Uganda

2021 ◽  
Vol 8 ◽  
Author(s):  
Michel Mainack Dione ◽  
Winfred Christine Amia ◽  
Francis Ejobi ◽  
Emily Awuor Ouma ◽  
Barbara Wieland
Keyword(s):  
Supply Chain ◽  
Large Scale ◽  
Service Providers ◽  
Production Systems ◽  
Animal Health ◽  
Livestock Production ◽  
Veterinary Drug ◽  
Small Scale ◽  
Drug Supply ◽  
Drug Supply Chain

This study assessed the veterinary drug supply chain in Uganda, the constraints faced by the actors, and how the challenges influence the use of antimicrobial (AMs) by livestock farmers. We carried out stakeholder consultation workshops, key informant interviews and a knowledge, practices, and awareness survey with actors of the veterinary drug supply chain. We also profiled drugs stored in 23 urban and peri-urban drug shops in Lira and Mukono districts to record the commonly sold drugs. The veterinary drug supply chain is made of several actors including wholesalers, retailers, Animal Health Service Providers (AHSP) and farmers. Nearly ninety per cent of drug retailers and veterinary practitioners did not receive specialized training in veterinary medicine, and most of veterinary practitioners have been in the drug business market for more than 10 years. Antibiotics and anti-helminthics were the most stocked drugs by retailers, with antibiotics ranking highest in terms of contribution to annual financial profits, accounting for 33%. The choice of a drug by veterinary practitioners was mainly informed by past success with efficacy of the drug, and financial capacity of the client (the farmer) to meet the treatment cost. Many veterinary practitioners were not conversant with veterinary drug policies of the country, with Mukono having a higher number (72%) compared to Lira (37%). Veterinary practitioners from Lira district compared to Mukono and those mainly serving small scale farmers relative to large scale smallholders were more knowledgeable about antibiotics and AMR. Several supply chain constraints were identified as potential drivers of misuse of antibiotics that could contribute to AMR. These included low level of education of supply chain actors, particularly drug retailers, poor handling of drugs at purchase and administration practices, low enforcement of policies and regulations, and lack of awareness of stakeholders about policies that regulate drug use. Thus, future interventions to reduce misuse of AM drugs in livestock production systems in Uganda such as capacity building, should also target veterinary input suppliers, and deliberately involve a strong policy advocacy component.

US trade policy is putting at risk the sustainability of the generic/biosimilar industry and the drug supply chain

2021 ◽  
pp. 174113432199431
Author(s):  
María Fabiana Jorge
Keyword(s):  
Supply Chain ◽  
Trade Policy ◽  
Pharmaceutical Products ◽  
Drug Supply ◽  
Active Pharmaceutical Ingredients ◽  
Pharmaceutical Ingredients ◽  
Us Trade Policy ◽  
Drug Supply Chain ◽  
Security Concern ◽  
The U.S

With the outbreak of the Coronavirus there is a new realization of the vulnerabilities of the U.S. drug supply chain. However, while such concerns may have been amplified by the pandemic, they preceded Covid-19 and were well documented before 2020. Indeed, in past years the U.S. Congress held several hearings addressing potential vulnerabilities in the U.S. drug supply chain, in part due to the increasing dependency on China as a dominant supplier of active pharmaceutical ingredients (APIs) and some finished pharmaceutical products. These vulnerabilities go well beyond health policy and constitute a national security concern. The article addresses how U.S. trade policy plays a significant role in shaping the pharmaceutical industry at home and abroad and is in part responsible for some of the current vulnerabilities of the U.S. drug supply chain.

Conservation of animal genetic resources: approaches and technologies for in situ and ex situ conservation

2008 ◽  
Vol 42 ◽  
pp. 71-85 ◽  
Author(s):  
J.A. Woolliams ◽  
O. Matika ◽  
J. Pattison
Keyword(s):  
Rural Communities ◽  
Genetic Resources ◽  
Large Scale ◽  
Production Systems ◽  
Regional Distribution ◽  
Livestock Production ◽  
Ex Situ ◽  
Animal Genetic Resources ◽  
The Face ◽  
Livestock Products

SummaryLivestock production faces major challenges through the coincidence of major drivers of change, some with conflicting directions. These are:1. An unprecedented global change in demands for traditional livestock products such as meat, milk and eggs.2. Large changes in the demographic and regional distribution of these demands.3. The need to reduce poverty in rural communities by providing sustainable livelihoods.4. The possible emergence of new agricultural outputs such as bio-fuels making a significant impact upon traditional production systems.5. A growing awareness of the need to reduce the environmental impact of livestock production.6. The uncertainty in the scale and impact of climate change. This paper explores these challenges from a scientific perspective in the face of the large-scale and selective erosion of our animal genetic resources, and concludes thai there is a stronger and more urgent need than ever before to secure the livestock genetic resources available to humankind through a comprehensive global conservation programme.

scholarly journals Supply chain resilience in a developing country context: a case study on the interconnectedness of threats, strategies and outcomes

2017 ◽  
Vol 22 (6) ◽  
pp. 486-505 ◽  
Author(s):  
Benjamin Tukamuhabwa ◽  
Mark Stevenson ◽  
Jerry Busby
Keyword(s):  
Supply Chain ◽  
Developing Country ◽  
Large Scale ◽  
Empirical Studies ◽  
Small Scale ◽  
Supply Network ◽  
Catastrophic Events ◽  
Content Type ◽  
Supply Chain Resilience

Purpose In few prior empirical studies on supply chain resilience (SCRES), the focus has been on the developed world. Yet, organisations in developing countries constitute a significant part of global supply chains and have also experienced the disastrous effects of supply chain failures. The purpose of this paper is therefore to empirically investigate SCRES in a developing country context and to show that this also provides theoretical insights into the nature of what is meant by resilience. Design/methodology/approach Using a case study approach, a supply network of 20 manufacturing firms in Uganda is analysed based on a total of 45 interviews. Findings The perceived threats to SCRES in this context are mainly small-scale, chronic disruptive events rather than discrete, large-scale catastrophic events typically emphasised in the literature. The data reveal how threats of disruption, resilience strategies and outcomes are inter-related in complex, coupled and non-linear ways. These interrelationships are explained by the political, cultural and territorial embeddedness of the supply network in a developing country. Further, this embeddedness contributes to the phenomenon of supply chain risk migration, whereby an attempt to mitigate one threat produces another threat and/or shifts the threat to another point in the supply network. Practical implications Managers should be aware, for example, of potential risk migration from one threat to another when crafting strategies to build SCRES. Equally, the potential for risk migration across the supply network means managers should look at the supply chain holistically because actors along the chain are so interconnected. Originality/value The paper goes beyond the extant literature by highlighting how SCRES is not only about responding to specific, isolated threats but about the continuous management of risk migration. It demonstrates that resilience requires both an understanding of the interconnectedness of threats, strategies and outcomes and an understanding of the embeddedness of the supply network. Finally, this study’s focus on the context of a developing country reveals that resilience should be equally concerned both with smaller in scale, chronic disruptions and with occasional, large-scale catastrophic events.

scholarly journals HONEYBEE PRODUCTION SYSTEM, CHALLENGES AND OPPORTUNITIES IN SELECTED DISTRICTS OF GEDEO ZONE, SOUTHERN NATION, NATIONALITIES AND PEOPLES REGIONAL STATE, ETHIOPIA

2016 ◽  
Vol 4 (4) ◽  
pp. 49-63
Author(s):  
Teklu Gebretsadik ◽  
Dinku Negash
Keyword(s):  
Production System ◽  
Large Scale ◽  
Market Access ◽  
Production Systems ◽  
Skill Training ◽  
Cross Sectional Study ◽  
Small Scale ◽  
Cross Sectional ◽  
Production Constraints ◽  
Regional State

The study was carried out in selected districts of Gedeo zones of southern Nation nationality and people’s regional state: such as Wonago, Kochere and DillaZuria/chichu/ districts. The objective of the study was to asses production systems, opportunities and constraints of apiculture farming in Gedeo zones of SNNPRs. Beekeeping is a long-standing practice in the study districts and appears as ancient history of the country as a whole. A cross sectional study, in which 90 households were purposively included and conducted in selected district to assess the current beekeeping practices, production potentials and production constraints. Most (72%) of the beekeepers in the study area have owned only traditional hives and produce honey for home consumption. The beekeeping practice was dominated by male.  Despite the area have  production constraints, the area opportunities like existence of large sized natural forest and artificial forest, due attention provision from regional, federal and local government and nongovernmental organizations, yearly flowering and variety floral availability, some small scale farmers highly experienced in apiculture farming, market access and high demand of apicultural products at nationally and international level. Therefore, Designing effective honeybee pests and predators controlling methods, Introduction of full package improved beekeeping technologies with adequate practical skill training on all bee keeping trends and queen rearing practices promoting beekeepers important indigenous knowledge, Producing areal major honeybee plants in large scale, Avoiding discarding of bee colonies after honey harvest, Availing the strategies to support farmers with beekeeping business support services, Improving pre- and post-harvest handling of bee products and Improving the utilization of stingless bee’s resources, without damaging the colony is important to make the honey production system in the area more economical, so as to enhance bee products for national and international need.

scholarly journals Optimizing Drug Supply Chain in Hospital Pharmacy Department: An Empirical Evidence from a Developing Country

2015 ◽  
Vol 5 (2) ◽  
pp. 153 ◽  
Author(s):  
John Mensah ◽  
Jonathan Annan ◽  
David Asamoah
Keyword(s):  
Supply Chain ◽  
Best Practices ◽  
Hospital Pharmacy ◽  
Primary Data ◽  
Drug Supply ◽  
Queuing Model ◽  
Pharmacy Department ◽  
The World ◽  
Reduced Costs ◽  
Drug Supply Chain

<p class="ber"><span lang="EN-GB">Healthcare organisations all over the world are looking for ways to improve operational efficiencies at reduced costs without affecting their services. This study was undertaken to first and foremost examine the supply chain practices at KATH Pharmacy, and secondly to assess those practices in the light of industrially accepted best practices. Primary data was obtained from fifty-five (55) respondents and the data were analysed using SPSS, and queuing model. </span><span lang="EN-US">Interesting findings emerged from the study, including patients spending an average of 12 minutes within the system of drug dispensing unit. However, this time can be reduced if the numbers of servers within the facility is increased by way of opening more dispensing outlets.</span></p>

Large Scale Physical Disruptions in the Electronic Communication Sector

2013 ◽  
pp. 50-60
Author(s):  
David Sutton
Keyword(s):  
Large Scale ◽  
Electronic Communication ◽  
Service Providers ◽  
Small Scale ◽  
Electronic Communications ◽  
Communication Sector

While small-scale disruptions that affect the electronic communications sector are frequent, their impact is generally relatively low, and recovery can be extremely fast. However, large-scale disruptions that have a major impact on the electronic communications sector are relatively uncommon. It is as a consequence of these two facts that Communications Service Providers (CSPs) place the majority of their effort (where possible) into the planning for prevention of small-scale disruptions, and recovery from those that do occur.

Blockchain Securing Drug Supply Chain

2021 ◽  
pp. 77-88
Author(s):  
Kavita Saini ◽  
Kavita Kumari ◽  
Shraddha Sagar
Keyword(s):  
Supply Chain ◽  
Drug Supply ◽  
Drug Supply Chain

scholarly journals Detection and Molecular Identification of Salmonella Virulence Genes in Livestock Production Systems in South Africa

Pathogens ◽  
2019 ◽  
Vol 8 (3) ◽  
pp. 124 ◽  
Author(s):  
Mthembu ◽  
Zishiri ◽  
Zowalaty
Keyword(s):  
South Africa ◽  
Salmonella Enterica ◽  
Virulence Genes ◽  
Production Systems ◽  
Livestock Production ◽  
Small Scale ◽  
Foodborne Diseases ◽  
Sampling Location ◽  
Salmonella Spp ◽  
Zoonotic Infections

Livestock are an important source of protein and food for humans, however opportunistic pathogens such as Salmonella spp. turn livestock into vehicles of foodborne diseases. This study investigated the prevalence of virulence genes in Salmonella spp. isolated from livestock production systems in two provinces of South Africa. During the period from May to August, 2018, a total of 361 faecal (189), oral (100), environmental (soil (36) and water (27)) and feed (9) samples were randomly collected from different animals (cattle, sheep, goats, pigs, ducks and chickens) that were housed in small-scale livestock production systems from Eastern Cape and KwaZulu-Natal Provinces in South Africa. Salmonella spp. were isolated and identified using microbiological and DNA molecular methods. Salmonella spp. were present in 29.0% of the samples of which 30.2% belonged to the Salmonella enterica species as confirmed by the positive amplification of the species specific iroB gene. Virulence genes that were screened from livestock-associated Salmonella were invA, iroB, spiC, pipD and int1. Statistically significant associations (p < 0.05) were established between the virulence genes, sampling location, animal host as well as the season when samples were collected. Furthermore, statistically significant (p < 0.05) positive correlations were observed between most of the virulence genes investigated. This is one of the recent studies to detect and investigate livestock-associated Salmonella spp. in South Africa. This study highlights the importance of continuous monitoring and surveillance for pathogenic salmonellae. It also demonstrated the detection and prevalence of virulent Salmonella spp. harbored by livestock in South Africa. This study demonstrated the potential risks of pathogenic Salmonella enterica to cause foodborne diseases and zoonotic infections from farm-to-fork continuum using the global one-health approach.

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