Knowledge and Practices on Antibiotic Use and Antibiotic Resistance Among Smallholder Pig Farmers in Timor-Leste

Antibiotic resistance is an emerging global health threat which is linked to the overuse and misuse of antibiotics. This study was conducted to understand the knowledge and practices of smallholder pig farmers on antibiotic use and resistance in Timor-Leste. A cross-sectional study using a structured face-to-face interview was conducted in three municipalities. The interview was piloted and implemented in the local Tetun language. This study found that knowledge of antibiotics was very poor as only 12.7% (95% CI: 6.3–23.9) of farmers reported knowing what antibiotics were, and of these only one was able to correctly explain how an antibiotic worked. None of the farmers knew about antibiotic resistance and were able to explain the concept correctly. After the definition of antibiotic was explained to the farmer, only 3.6% (95% CI: 0.8–14.9) reported that their pigs had ever received antibiotics, and the majority of farmers whose pigs had not received antibiotics reported the lack of access to veterinary services. When used, antibiotics were only used for treatment with no reported use for disease prevention or growth promotion. None of the commonly used antibiotics were critically important antimicrobials. Compliance with withdrawal periods was not routinely followed. There is a need to improve access to government veterinary services for farmers in Timor-Leste, while addressing identified knowledge gaps on antibiotics and promoting prudent use practices. The findings from this study serve as baseline information to inform future interventions.

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Prescribers’ Knowledge, Attitudes and Behaviors on Antibiotics, Antibiotic Use and Antibiotic Resistance in Jordan

Antibiotics ◽

10.3390/antibiotics10070858 ◽

2021 ◽

Vol 10 (7) ◽

pp. 858

Author(s):

Reema A. Karasneh ◽

Sayer I. Al-Azzam ◽

Mera Ababneh ◽

Ola Al-Azzeh ◽

Ola B. Al-Batayneh ◽

...

Keyword(s):

Antibiotic Resistance ◽

Antibiotic Use ◽

Cross Sectional Study ◽

Antibiotic Prescribing ◽

Prescribing Practices ◽

Online Questionnaire ◽

Cross Sectional ◽

Attitudes And Behaviors ◽

And Behaviors ◽

Ease Of Access

More research is needed on the drivers of irrational antibiotic prescribing among healthcare professionals and to ensure effective prescribing and an adequate understanding of the issue of antibiotic resistance. This study aimed at evaluating prescribers’ knowledge, attitudes and behaviors about antibiotic use and antibiotic resistance. A cross-sectional study was conducted utilizing an online questionnaire and included physicians and dentists from all sectors in Jordan. A total of 613 prescribers were included (physicians n = 409, dentists n = 204). Respondents’ knowledge on effective use, unnecessary use or associated side effects of antibiotics was high (>90%), compared with their knowledge on the spread of antibiotic resistance (62.2%). For ease of access to the required guidelines on managing infections, and to materials that advise on prudent antibiotic use and antibiotic resistance, prescribers agreed in 62% and 46.1% of cases, respectively. 28.4% of respondents had prescribed antibiotics when they would have preferred not to do so more than once a day or more than once a week. Among respondents who prescribed antibiotics, 63.4% would never or rarely give out resources on prudent use of antibiotics for infections. The findings are of importance to inform antibiotic stewardships about relevant interventions aimed at changing prescribers’ behaviors and improving antibiotic prescribing practices.

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Antibiotics stewardship in Ghana: a cross-sectional study of public knowledge, attitudes, and practices

10.21203/rs.2.19809/v1 ◽

2020 ◽

Author(s):

Tamara Jimah ◽

Ama P. Fenny ◽

Oladele Ogunseitan

Keyword(s):

Antibiotic Resistance ◽

Inappropriate Medication ◽

Antibiotic Use ◽

Antibiotic Consumption ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Attitudes And Practices ◽

Individual Knowledge ◽

Knowledge Attitudes And Practices

Abstract Background Antibiotic resistance is a major contributing factor to global morbidity and mortality and is associated with inappropriate medication use. However, the level of antibiotic consumption and knowledge about antibiotic resistance in Ghana is inadequately quantified. Our study identifies strategies for improved stewardship of antibiotics to prevent the proliferation of resistant pathogens by assessing the level of antibiotic knowledge, attitudes, and consumption behaviors by region, gender, age, and education in rural and urban Ghana. Methods A cross-sectional study was conducted in 12 communities in the urban Greater Accra and rural Upper West regions of Ghana. A questionnaire survey was administered to 400 individuals aged 18 years and older in selected locations during September-October 2018 to gather data on individual knowledge, attitudes, and practices concerning antibiotics and antibiotic resistance. Multivariate analysis was used to investigate the association between demographic characteristics and knowledge, attitudes, and related behaviors. Results Over 30% (125/400) had not received a doctor’s prescription during their last illness. Seventy percent (278/400) had taken at least one antibiotic in the year prior to the survey. The top five frequently used antibiotics were Amoxicillin , Amoxicillin-clavulanic acid , Ampicillin , Ciprofloxacin , and Metronidazole . Women and older adults had higher knowledge compared to their respective counterparts (p<0.01). Furthermore, prudent antibiotic use was significantly more prevalent in women than men (p<0.05). Although no regional differences were found in overall knowledge, compared to urban residents, individuals residing in rural settings exhibited higher knowledge about the ineffectiveness of antibiotics for viruses like the cold and HIV/AIDS (p<0.001). Two hundred and fifty-two (63%) respondents were unaware of antibiotic resistance. There was generally a low level of self-efficacy among participants regarding their role in preserving the effectiveness of antibiotics. Conclusion Antibiotic knowledge, attitudes, and use varied significantly across demographics, suggesting a context-specific approach to developing effective community interventions.

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Public awareness regarding the use and resistance of antibiotics: A cross-sectional study among Nepalese adults in Kathmandu valley

Journal of Kathmandu Medical College ◽

10.3126/jkmc.v6i3.19823 ◽

2018 ◽

Vol 6 (3) ◽

pp. 96-101

Author(s):

Satish Kumar Deo ◽

Sita Rijal ◽

Tulza K.C

Keyword(s):

Antibiotic Resistance ◽

Public Awareness ◽

Study Finding ◽

Antibiotic Use ◽

Cross Sectional Study ◽

Public Health Issue ◽

Sectional Study ◽

Cross Sectional ◽

Interview Method ◽

Drug Classes

Background: Antibiotics are considered to be among the most commonly sold drug classes globally. Antibiotic resistance is a recognized public health issue at the local, national and global levels.Objectives: The aim of this study was to identify awareness of general public regarding the use and resistance of antibiotics.Methodology: A descriptive cross-sectional study was conducted in Kathmandu in November 2016 using a quantitative questionnaire among 120 adult people aged 20–60 years. Convenience sampling method was used and information on use of antibiotics and resistance was obtained using semi-structured questionnaire through interview method. Descriptive statistics was done to describe the respondent’s level of awareness regarding use of antibiotics and resistance.Results: Among the total respondents, majority had incorrect awareness as regards to action, reasons for using antibiotics, possible side effects of the antibiotic. Seventy one percent of the respondents had not heard about antibiotic resistance. The study finding showed that about 66.7% of the participants had inadequate awareness towards use and resistance of antibiotics.Conclusion: The findings demonstrate that the overall awareness on antibiotic use and resistance is poorly understood among our respondents. This information can be utilized in future educational and antibiotic resistance awareness raising campaigns.

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Differences in antibiotic use and knowledge between adolescent and adult mothers in Ecuador

F1000Research ◽

10.12688/f1000research.2-108.v2 ◽

2013 ◽

Vol 2 ◽

pp. 108

Author(s):

Arturo Quizhpe P ◽

Martyna Gassowski ◽

Lorena Encalada T ◽

Francoise Barten

Keyword(s):

Antibiotic Resistance ◽

Adolescent Mothers ◽

Antibiotic Use ◽

Cross Sectional Study ◽

Medical Attention ◽

Upper Respiratory Tract ◽

Cross Sectional ◽

The Social ◽

Treatment Knowledge ◽

Basic Services

Objectives: To investigate the differences in antibiotic use and knowledge between adolescent and adult mothers of children under the age of 5 years in Ecuador.Methods: A cross sectional study was performed in four health centers and hospitals. Mothers of children under five years, seeking medical attention their child's upper respiratory tract infection (URI), were included. The data was collected through interviews, using a structured questionnaire. The questionnaire covered the topics knowledge of antibiotic treatment, risk and resistance. Results: 777 mothers were included in the study, of which 15.8% were adolescent and 84.1% adult mothers. There were significant differences in the social and economic characteristics of the mothers (p ≤ 0.05), with adolescent mothers being more likely to have an incomplete high school education and lack of basic services in their home. Significant differences between these groups were found in adherence to treatment, knowledge about risks associated with antibiotic use, and having heard of antibiotic resistance. Among the adult mothers, 83.5% reported correct adherence, 28.5% were knowledgeable about risks associated with antibiotic use, and 29.3% had heard of antibiotic resistance. Among the adolescent mothers, these numbers were 75.4%, 15.0%, and 19.8%, respectively.Conclusions: To develop successful interventions, it is crucial to understand the factors causing differences in antibiotic use and knowledge between mothers.

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Understanding of Pharmacy Students towards Antibiotic Use, Antibiotic Resistance and Antibiotic Stewardship Programs: A Cross-Sectional Study from Punjab, Pakistan

Antibiotics ◽

10.3390/antibiotics10010066 ◽

2021 ◽

Vol 10 (1) ◽

pp. 66

Author(s):

Khezar Hayat ◽

Shazia Jamshed ◽

Meagen Rosenthal ◽

Noman Ul Haq ◽

Jie Chang ◽

...

Keyword(s):

Antibiotic Resistance ◽

Antibiotic Stewardship ◽

Antibiotic Use ◽

Cross Sectional Study ◽

Pharmacy Students ◽

Cross Sectional ◽

Adequate Understanding ◽

Self Administered Questionnaire ◽

And Training ◽

Insight Into

Antibiotic resistance (ABR) is a significant issue for public health globally. An adequate understanding of ABR and the approaches used to tackle ABR, including antibiotic stewardship programs, are vital. This study aimed to get an insight into antibiotic use, ABR, and antibiotic stewardship programs among pharmacy students of Punjab, Pakistan. This multicenter study was undertaken among final (fifth) year undergraduate pharmacy students of 7 universities of Punjab, Pakistan. A paper-based self-administered questionnaire comprising 48-items was utilized for data collection. Descriptive and inferential statistics were employed for data analysis. This study included a total of 296 respondents with a response rate of 85.8%. Most of the students had an average understanding of antibiotic use (59.8%), ABR (42.6%), ABR mechanisms (48.0%), and factors of ABR (51.7%). Only 21.6% of students have heard about antibiotic stewardship programs. More than half of the students believed that educating and training healthcare professionals (53.4%) and medical students (57.8%) about the prescribing and judicial usage of antibiotics could reduce the ABR burden. The awareness of most of the pharmacy students about certain aspects of antibiotic use, ABR, and stewardship programs was suboptimal.

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Prescription Antibiotic Use among the US population 1999-2018: National Health and Nutrition Examination Surveys

Open Forum Infectious Diseases ◽

10.1093/ofid/ofab224 ◽

2021 ◽

Author(s):

Molly Petersen ◽

Sara E Cosgrove ◽

Thomas C Quinn ◽

Eshan Patel ◽

M Kate Grabowski ◽

...

Keyword(s):

United States ◽

Antibiotic Resistance ◽

National Health ◽

Prevalence Ratio ◽

Antibiotic Use ◽

The United States ◽

Cross Sectional Study ◽

Cross Sectional ◽

Health And Nutrition ◽

Poverty Status

Abstract Background Antibiotic resistance has been identified as a public health threat both in the United States and globally. The United States published the “National Strategy for Combating Antibiotic Resistance” in 2014, which included goals to reduce inappropriate outpatient antibiotic use. Methods This cross-sectional study was conducted using National Health and Nutrition Examination Surveys (NHANES) years 1999-2018. Weighted prevalence of past 30-day non-topical outpatient antibiotic use was calculated, as well as the change in prevalence from 1999-02 to 2015-18 and 2007-10 to 2015-18, both overall and for subgroups. Associations with past 30-day non-topical outpatient antibiotic use in 2015-18 were examined using predictive margins calculated by multivariable logistic regression. Results The overall prevalence of past 30-day non-topical outpatient antibiotic use adjusted for age, sex, race/ethnicity, poverty status, time of year of the interview, and insurance status from 1999-2002 to 2015-2018 changed significantly from 4.9% (95% CI 3.9%, 5.0%) to 3.0% (95% CI 2.6%, 3.0%), with the largest decrease among children 0-1 years. From 2007-2010 to 2015-2018, there was no significant change (adjusted Prevalence Ratio [adjPR] 1.0 [95% CI 0.8, 1,2. Age was significantly associated with antibiotic use, with children age 0-1 years having significantly higher antibiotic use than all other age categories >6 years. Being non-Hispanic Black was negatively associated with antibiotic use as compared to being non-Hispanic White (adjPR 0.6 [95% CI 0.4, 0.8]). Conclusions While there were declines in antibiotic use from 1999-02 to 2015-18, there were no observed declines during the last decade.

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Antibiotic resistance among the Lahu hill tribe people, northern Thailand: a cross-sectional study

BMC Infectious Diseases ◽

10.1186/s12879-021-06087-7 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Sophaphan Intahphuak ◽

Tawatchai Apidechkul ◽

Patita Kuipiaphum

Keyword(s):

Public Health ◽

Escherichia Coli ◽

Drug Resistance ◽

Antibiotic Resistance ◽

Antibiotic Use ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Hill Tribe ◽

The Hill

Abstract Background Antibiotic resistance is often reported and great concerned as one of public health problems especially people living with poverty in developing countries including Thailand. The hill tribe people is defined as vulnerable population for antibiotic resistance in Thailand due to poor economic and education status particularly the Lahu people who is the second greatest group of the hill tribe people in Thailand. The study aimed to estimate the prevalence, factors associated with, and typing major species of bacteria with antibiotic drugs resistance among the Lahu hill tribe people in northern Thailand. Methods A cross-sectional study was conducted to gather the information from the participants. A validated questionnaire was used for data collection. Participants who presented an illness related to infectious diseases were eligible to participate the study and were asked to obtain specific specimen; sputum, urine or stool. Antibiotic susceptibility was tested by Kirbey Bauer’s disc diffusion test. Chi-square and logistic regression were used to detect the associations between variables at the significant level of α = 0.05. Results A total of 240 participants were recruited into the study. The majority had urinary tract infection (67.9%) with two major pathogenic species of the infection; Escherichia coli (12.8%), and Enterobacter cloacae (8.0%). The prevalence of antibiotic resistance was 16.0%. Escherichia coli and Klebsiella pneumoniae species were found to have multidrug resistance that was greater than that of other species, while ampicillin was found to have the greatest drug resistance. It was found that those who had poor knowledge of antibiotic use had a 2.56-fold greater chance (95% CI = 1.09–5.32) of having antibiotic resistance than did those who had good knowledge of antibiotic use, and those who had poor antibiotic use behaviors had a 1.79-fold greater chance (95% CI = 1.06–4.80) of having antibiotic resistance than did those who had good antibiotic use behaviors. Conclusion Effective public health interventions are urgently needed to reduce antibiotic drug resistance among the Lahu people by improving their knowledge and skills regarding the proper use of antibiotics and eventually minimizing antibiotic resistance. Moreover, health care professionals should strictly follow the standard guideline to prescribe antibiotics.

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Antibiotic resistance among the Lahu hill tribe people in northern Thailand: a cross-sectional study

10.21203/rs.3.rs-27927/v1 ◽

2020 ◽

Author(s):

SOPHAPHAN INTAHPHUAK ◽

TAWATCHAI APIDECHKUL ◽

PATITA KUIPIAPHUM

Keyword(s):

Public Health ◽

Escherichia Coli ◽

Drug Resistance ◽

Antibiotic Resistance ◽

Antibiotic Use ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Hill Tribe ◽

Antibiotic Drug

Abstract Background Antibiotic resistance is often reported and is of major concern as a public health problem. The hill tribe people in Thailand are considered populations vulnerable to antibiotic resistance due to their poor economic and educational status. The study aimed to estimate the prevalence of, the factors associated with, and the major species of bacteria involved in antibiotic drug resistance among the Lahu hill tribe people in northern Thailand. Methods A cross-sectional study was conducted to gather information from participants between March and September 2019. A validated questionnaire was used for data collection. Participants who presented an illness related to infectious diseases were eligible to participate in the study and were asked to obtain specific specimens. Antibiotic susceptibility was tested by the Kirbey-Bauer disk diffusion test. Chi-square tests and logistic regression were used to detect the associations between variables at the significance level of α = 0.05. Results A total of 240 participants were recruited into the study; 70.4% were females, 25.4% were aged 30–40 years. More than half worked in the agricultural sector (55.4%) and had an education level of less than primary school (45.8%). The majority had urinary tract infections (67.9%) with two major pathogenic species of the infection: Escherichia coli (12.8%) and Enterobacter cloacae (8.0%). The prevalence of antibiotic resistance was 16.0%. Escherichia coli and Klebsiella pneumoniae species were found to have multidrug resistance that was greater than that of other species, while ampicillin was found to have the greatest drug resistance. In the multivariate model, it was found that those who had poor knowledge of antibiotic use had a 2.56-fold greater chance (95% CI = 1.09–5.32) of having antibiotic resistance than did those who had good knowledge of antibiotic use, and those who had poor antibiotic use behaviors had a 1.79-fold greater chance (95% CI = 1.06–4.80) of having antibiotic resistance than did those who had good antibiotic use behaviors. Conclusion Effective public health interventions are urgently needed to reduce antibiotic drug resistance among the Lahu people by improving their knowledge and skills regarding the proper use of antibiotics and eventually minimizing antibiotic resistance.

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Antibiotics stewardship in Ghana: a cross-sectional study of public knowledge, attitudes, and practices among communities.

10.21203/rs.2.19809/v2 ◽

2020 ◽

Author(s):

Tamara Jimah ◽

Ama P. Fenny ◽

Oladele Ogunseitan

Keyword(s):

Antibiotic Resistance ◽

Inappropriate Medication ◽

Antibiotic Use ◽

Antibiotic Consumption ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Attitudes And Practices ◽

Individual Knowledge ◽

Knowledge Attitudes And Practices

Abstract Background Antibiotic resistance is a major contributing factor to global morbidity and mortality and is associated with inappropriate medication use. However, the level of antibiotic consumption and knowledge about antibiotic resistance in Ghana is inadequately quantified. Our study identifies strategies for improved stewardship of antibiotics to prevent the proliferation of resistant pathogens by assessing the level of antibiotic knowledge, attitudes, and consumption behaviors by region, gender, age, and education in rural and urban Ghana. Methods A cross-sectional study was conducted in 12 communities in the urban Greater Accra and rural Upper West regions of Ghana. A questionnaire survey was administered to 400 individuals aged 18 years and older in selected locations during September-October 2018 to collect data on individual knowledge, attitudes, and practices concerning antibiotics and antibiotic resistance. Multivariate analysis was used to investigate the association between demographic characteristics and knowledge, attitudes, and related behaviors. Results Over 30% (125/400) had not received a doctor’s prescription during their last illness. Seventy percent (278/400) had taken at least one antibiotic in the year prior to the survey. The top five frequently used antibiotics were Amoxicillin, Amoxicillin-clavulanic acid, Ampicillin, Ciprofloxacin, and Metronidazole. Women and older adults had higher knowledge compared to their respective counterparts (p<0.01). Furthermore, prudent antibiotic use was significantly more prevalent in women than men (p<0.05). Although no regional differences were found in overall knowledge, compared to urban residents, individuals residing in rural settings exhibited higher knowledge about the ineffectiveness of antibiotics for viruses like the cold and HIV/AIDS (p<0.001). Two hundred and fifty-two (63%) respondents were unaware of antibiotic resistance. There was generally a low level of self-efficacy among participants regarding their role in preserving the effectiveness of antibiotics. Conclusion Antibiotic knowledge, attitudes, and use varied significantly across demographics, suggesting a context-specific approach to developing effective community interventions.

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Antibiotic use: evaluating knowledge, attitude and practices among medical students in a sub Himalayan state

International Journal of Basic & Clinical Pharmacology ◽

10.18203/2319-2003.ijbcp20174387 ◽

2017 ◽

Vol 6 (10) ◽

pp. 2516 ◽

Cited By ~ 1

Author(s):

Rajiv Kumar Gupta ◽

Parveen Singh ◽

Renu Rani ◽

Rashmi Kumari ◽

Bhavna Langer ◽

...

Keyword(s):

Antibiotic Resistance ◽

Medical Students ◽

Viral Infections ◽

Antibiotic Use ◽

Cross Sectional Study ◽

World Health ◽

Chi Square ◽

Cross Sectional ◽

Attitudes And Practices ◽

Health Organization

Background: The growing concern about antibiotic resistance, of late, led World Health Organization to declare it as World Health Day theme in 2011. Knowledge spreads awareness and understanding by melting the barriers of ignorance while attitudes and practices have a bearing on the health related behaviour. The present study aims at evaluating the knowledge, attitudes and practices of medical students towards antibiotic usage.Methods: The present cross-sectional study was conducted among the Pre-final medical students (6th / 7th semester) who participated in the questionnaire survey on knowledge, attitude and practice towards antibiotics usage. The data was analysed and Chi-square was used as test of significance.Results: Overall, 132 students were interviewed. Majority (96.2%) had heard of antibiotic resistance. About 22% of the sample stated that antibiotics can cure viral infections, among them female being in the higher proportion (p<0.05). Majority (>90%) agreed that antibiotic resistance is a serious problem and had positive attitude about population awareness campaign regarding antibiotic resistance. Among practices, higher proportion of male respondents preferred antibiotics in case of cough and sore throat. (p<0.05).Conclusions: Despite being Pre-final MBBS students, the results have revealed that knowledge and attitude of the respondents were not up to the desired levels. The practices regarding use of antibiotics were more or less adequate. For effective curriculum, thorough knowledge and rational prescription of antibiotics needs to be reinforced among medical students both before and during internship.

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