scholarly journals Evaluation of Soil S Pools under 23 Years of Maize Monoculture

Agronomy ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 2376
Author(s):  
Pavel Suran ◽  
Martin Kulhánek ◽  
Jiří Balík ◽  
Jindřich Černý ◽  
Ondřej Sedlář
Keyword(s):  
High Dose ◽  
The Czech Republic ◽  
S Uptake ◽  
Biomass Yields ◽  
Entire Experiment ◽  
Initial Content ◽  
Phosphorus And Potassium ◽  
Very High ◽  
Sulfur Nutrition

Sulfur nutrition is a critical part of proper crop growth and development. In our study, biomass yields (BY) and S uptake were investigated on long-term maize monoculture on haplic luvisol soil during the 23 years of this trial, as well as changes in water extractable (Sw), adsorbed (Sads), mineral (Sav), and pseudo-total S (St) fractions. Treatments used in this study are: (1) Control (Cont); (2) ammonium sulfate (AS); (3) urea and ammonium nitrate (UAN); (4) UAN + phosphorus and potassium (UAN + PK); (5) UAN + phosphorus, magnesium, sulfur (UAN + PMgS); and (6) Fallow. Recently, the Mehlich 3 method started to be used in the Czech Republic to determine content of plant available S. Using this method, it was found that the content of S extracted by Mehlich 3 (SM3) closely correlates to Sav in both topsoil and subsoil (r = 0.958 in 1997 and 0.990 in 2019, both at p < 0.001). We also found that, on average, during the entire experiment, all treatments had increased yields over Cont (135–147%) and increased S uptake (291, 192, 180, and 246% of Cont for AS, UAN, UAN + PK, and UAN + PMgS, respectively). Examining the changes from 1997 to 2019 in topsoil (0–30 cm depth), we discovered a decrease of S content in Sw, Sads, Sav, and St fractions on all treatments to an average of 34.6%, 65.8%, 42.2%, and 78.6% of their initial values. The exception was AS treatment, which doubled its initial content in mineral fractions and maintained the same levels of St, and which we attribute to the very high dose of S on this treatment (142 kg ha−1 year−1). Using the simple balance method, AS and UAN + PMgS treatments lost 142.2 and 95.3 kg S ha−1 year−1 to other sinks, except plant uptake, from the entire soil profile (0–60 cm) during 23 years of experiment. Other treatments also show significant losses with the exception of Fallow. Given these results, it is clear that content of sulfur in soil is generally decreasing and attention should be paid mainly towards minimizing of its losses.

scholarly journals Can very high-dose anti-tumor necrosis factor blockade at onset of rheumatoid arthritis produce long-term remission?

2002 ◽  
Vol 46 (7) ◽  
pp. 1971-1972 ◽  
Author(s):  
Philip G. Conaghan ◽  
Mark A. Quinn ◽  
Philip O'Connor ◽  
Richard J. Wakefield ◽  
Zunaid Karim ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Tumor Necrosis Factor ◽  
Tumor Necrosis ◽  
High Dose ◽  
Very High ◽  
Necrosis Factor

scholarly journals Immunosuppressive therapy of aplastic anemia: results of a prospective, randomized trial of antithymocyte globulin (ATG), methylprednisolone, and oxymetholone to ATG, very high-dose methylprednisolone, and oxymetholone

Blood ◽  
1992 ◽  
Vol 79 (10) ◽  
pp. 2566-2571 ◽  
Author(s):  
K Doney ◽  
M Pepe ◽  
R Storb ◽  
E Bryant ◽  
C Anasetti ◽  
...  
Keyword(s):  
Acute Leukemia ◽  
Aplastic Anemia ◽  
Causes Of Death ◽  
Response To Therapy ◽  
High Dose ◽  
Actuarial Survival ◽  
High Dose Methylprednisolone ◽  
Significant Difference ◽  
Very High

Abstract Sixty-eight patients with moderate (n = 15) or severe (n = 53) aplastic anemia were entered into a prospective, randomized, two-arm treatment study comparing antihuman thymocyte globulin (ATG), lower-dose methylprednisolone (LDM) and oxymetholone to ATG, higher-dose methylprednisolone (HDM), and oxymetholone. There were no differences between the two groups when comparing age, sex, etiology of aplasia, disease duration, severity of aplasia, or pretherapy granulocyte counts. Side effects of LDM and HDM were similar. Of the 64 patients evaluable for response to therapy, 12 of 33 (36%) who received LDM had complete, partial, or minimal responses compared with 15 of 31 patients (48%) who received HDM (P = .33). Actuarial survival at 4 years is 43% for patients in the LDM group and 47% for patients in the HDM group (P = .99). Causes of death included hemorrhage, infection, evolution to acute leukemia, and complications of subsequent bone marrow transplantation. Long-term complications included paroxysmal nocturnal hemoglobinuria (n = 3), evolution to myelodysplasia or acute leukemia (n = 6), and recurrent aplasia (n = 6). We were unable to show a significant difference in toxicity, response rate, or survival for patients treated with ATG, oxymetholone, and LDM compared with patients who received ATG, oxymetholone, and HDM.

Long-term complication risk after very high dose thoracic radiotherapy

2002 ◽  
Vol 54 (2) ◽  
pp. 106 ◽  
Author(s):  
M.S Anscher ◽  
L.B Marks ◽  
T.D Shafman ◽  
R Clough ◽  
H Huang ◽  
...  
Keyword(s):  
High Dose ◽  
Thoracic Radiotherapy ◽  
Complication Risk ◽  
Very High

Mo1595 Long-Term Cardiac Safety of Very High-Dose Domperidone for the Treatment of Gastroparesis: A Single Center Experience

2016 ◽  
Vol 150 (4) ◽  
pp. S723
Author(s):  
Marco A. Bustamante Bernal ◽  
Jose L. Gonzalez Martinez ◽  
Alejandro Barreda ◽  
Yvette Gomez ◽  
Richard W. McCallum
Keyword(s):  
High Dose ◽  
Single Center ◽  
Cardiac Safety ◽  
Single Center Experience ◽  
Very High

Surface evolution of very high dose arsenic implants in silicon formed by plasma immersion ion implantation - a long term study

2013 ◽  
Vol 11 (1) ◽  
pp. 28-31 ◽  
Author(s):  
Florian Meirer ◽  
Evgeny Demenev ◽  
Damiano Giubertoni ◽  
Lia Vanzetti ◽  
Salvatore Gennaro ◽  
...  
Keyword(s):  
Ion Implantation ◽  
High Dose ◽  
Term Study ◽  
Surface Evolution ◽  
Long Term Study ◽  
Plasma Immersion Ion Implantation ◽  
Very High

Very-high-dose cisplatin with bleomycin infusion as initial treatment of advanced head and neck cancer.

1987 ◽  
Vol 5 (10) ◽  
pp. 1594-1600 ◽  
Author(s):  
I Haines ◽  
G Bosl ◽  
D Pfister ◽  
R Spiro ◽  
F Gerold ◽  
...  
Keyword(s):  
Head And Neck ◽  
Pulmonary Function Tests ◽  
Locally Advanced ◽  
Local Therapy ◽  
High Dose ◽  
Overall Response ◽  
Squamous Cancer ◽  
Chemotherapy Patients ◽  
Very High

Fifty-one patients with locally advanced squamous cancer of the head and neck (SCHN) were treated with up to three cycles of very-high-dose cisplatin, 187.5 mg/m2 (administered over five days) in hypertonic saline, and bleomycin infusion, 60 U/m2 (administered over five days), prior to definitive local therapy, in an attempt to improve complete remission (CR) and overall response rates. After chemotherapy, patients underwent surgery if the tumor was resectable for cure, (unless the operation involved total laryngectomy), and/or locoregional radiation therapy. Twelve patients (24%) achieved CR and 23 (45%) partial remission (PR) for an overall response rate of 69%. Thirty-nine of the 51 patients are evaluable following chemotherapy and locoregional treatment, and 28 (72%) have achieved disease-free status. Seven of these 28 (25%) have subsequently relapsed. Eleven of the 51 patients (22%) have died at median follow-up of 10+ months (3+ to 24+). Nausea and vomiting (94%) was the most severe acute toxicity. Myelosuppression was mild and nephrotoxicity was effectively prevented by the 3% saline diuresis. Bleomycin was withheld in 12 of 49 (24%) because of deterioration in pulmonary function tests. Ototoxicity in 12 of 49 (25%) and neurotoxicity in 19 of 49 (39%) were the most significant long-term toxicities. Very-high-dose cisplatin and bleomycin in this study was an effective chemotherapy regimen, but not more so than more conventional doses of cisplatin. Toxicity from both drugs was significant.

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