scholarly journals Effects of Chronic Thermal Stress on Performance, Energy Metabolism, Antioxidant Activity, Brain Serotonin, and Blood Biochemical Indices of Broiler Chickens

Animals ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 2554
Author(s):  
Omar Ahmed-Farid ◽  
Ayman S. Salah ◽  
Mohamed Abdo Nassan ◽  
Mahmoud S. El-Tarabany
Keyword(s):  
Thermal Stress ◽  
Energy Metabolism ◽  
Broiler Chickens ◽  
Antioxidant Defense System ◽  
Blood Parameters ◽  
Brain Serotonin ◽  
Blood Biochemical ◽  
Biochemical Indices ◽  
Blood Biochemical Indices ◽  
Liver Tissues

The aim of this paper was to investigate the effects of chronic thermal stress on the performance, energy metabolism, liver CoQ10, brain serotonin, and blood parameters of broiler chickens. In total, 100 one-day-old chicks were divided into two equal groups of five replicates. At 22 days of age and thereafter, the first group (TN) was maintained at a thermoneutral condition (23 ± 1 °C), while the second group (TS) was subjected to 8 h of thermal stress (34 °C). The heat-stressed group showed significantly lower ADFI but higher FCR than the thermoneutral group (p = 0.030 and 0.041, respectively). The TS group showed significantly higher serum cholesterol, ALT, and AST (p = 0.033, 0.024, and 0.010, respectively). Meanwhile, the TS group showed lower serum total proteins, albumin, globulin, and Na+ than the TN group (p = 0.001, 0.025, 0.032, and 0.002, respectively). Furthermore, the TS group showed significantly lower SOD and catalase in heart tissues (p = 0.005 and 0.001, respectively). The TS group showed significantly lower liver ATP than the TN group (p = 0.005). Meanwhile, chronic thermal stress significantly increased the levels of ADP and AMP in the liver tissues of broiler chickens (p = 0.004 and 0.029, respectively). The TS group showed significantly lower brain serotonin (p = 0.004) and liver CoQ10 (p = 0.001) than the TN group. It could be concluded that thermal stress disturbed the antioxidant defense system and energy metabolism and exhausted ATP levels in the liver tissues of broiler chickens. Interestingly, chronic thermal stress reduced the level of brain serotonin and the activity of CoQ10 in liver tissues.

scholarly journals Dietary Curcumin Improves Energy Metabolism, Brain Monoamines, Carcass Traits, Muscle Oxidative Stability and Fatty Acid Profile in Heat-Stressed Broiler Chickens

Antioxidants ◽  
2021 ◽  
Vol 10 (8) ◽  
pp. 1265
Author(s):  
Ayman S. Salah ◽  
Omar A. Ahmed-Farid ◽  
Mohamed Abdo Nassan ◽  
Mahmoud S. El-Tarabany
Keyword(s):  
Fatty Acids ◽  
Thermal Stress ◽  
Energy Metabolism ◽  
Oxidative Stability ◽  
Broiler Chickens ◽  
Basal Diet ◽  
Brain Serotonin ◽  
Brain Monoamines ◽  
Thigh Muscles ◽  
Liver Tissues

The aim of the present study was to elucidate the impacts of dietary curcumin supplementation on energy metabolism, brain monoamines and muscle oxidative stability in heat-stressed broilers. In total, 120 day-old chicks were allocated into three equal groups of four replicates. The first group (T1) was maintained on a thermoneutral condition, while the second group (T2) was subjected to 8 h of thermal stress (34 °C), and both groups fed the basal diet with no supplement. The third group (T3) was exposed to the same thermal stress conditions and fed the basal diet supplemented with curcumin (100 mg kg−1 diet). The dietary curcumin supplementation significantly increased the breast yield (p = 0.004), but reduced the percentage of abdominal fat (p = 0.017) compared with the T2 group. The addition of curcumin to broiler diets significantly improved the levels of monounsaturated fatty acids (MUFAs) and polyunsaturated fatty acids (PUFAs) in breast and thigh muscles compared with the T2 group (p < 0.05). The curcumin-supplemented group showed significantly lower levels of malondialdehyde in the breast and thigh muscles than that of the T2 group (p = 0.001 and 0.015, respectively). The dietary curcumin supplementation significantly improved the levels of ATP and CoQ10 in liver tissues (p = 0.012 and 0.001, respectively) and brain serotonin (p = 0.006) as compared to the T2 group. Meanwhile, the heat-stressed group showed significantly higher levels of ADP and Na,K-ATPase in the liver tissues than that of the other experimental groups (p = 0.011 and 0.027, respectively). It could be concluded that dietary curcumin supplementation may improve carcass yield, energy biomarkers, brain serotonin and muscle oxidative stability of heat-stressed broiler chickens.

scholarly journals Performance, Immuno-stimulatory and Blood Biochemical Indices of Broiler Chickens Fed Hot Red Pepper (Capsicum annuum L.) Supplemented Diets

2019 ◽  
pp. 1-8
Author(s):  
A. A. Adedoyin ◽  
M. A. Mosobalaje ◽  
A. I. Bamimore
Keyword(s):  
Weight Gain ◽  
Broiler Chickens ◽  
Density Lipoprotein ◽  
Conversion Ratio ◽  
Feed Conversion Ratio ◽  
Red Pepper ◽  
Feed Conversion ◽  
Blood Biochemical ◽  
Biochemical Indices ◽  
Blood Biochemical Indices

A study was conducted to evaluate the effects of hot red pepper (HRP) powder as a natural feed additive on performance, immunity and blood biochemical parameters in broiler chickens. A Completely Randomized Design (CRD) was adopted by using 180 two weeks old Anak broiler chicks, allocated to four treatments with nine replicates of five birds each. Commercial broiler diets used containing HRP at the levels of 0%, 1.0%, 1.25% and 1.5%. Results showed that HRP supplementation did not significantly increase (p>0.05) the Average Feed Intake (AFI). Also not significant (p>0.05) but birds fed with the control diet had the numerically lowest Average Body Weight Gain (ABWG) (38.11 g) and worst Feed Conversion Ratio (FCR) (1.96). Better cost/kg weight gain was also found in the birds fed with the HRP supplemented diets. Mortality was however, significantly (p>0.05) higher in control diets compared to other diets. Packed cell volume (PCV), haemoglobin (HG), and white blood cell (WBC) levels were not significantly (p>0.05) different among the experimental groups. At the same time, HRP dietary supplementation did not have a significant effect on serum biochemical parameters (Aspartate aminotransferase (AST), Alanine aminotransferase (ALT), Lactate dehydrogenase (LDH), Low-density lipoprotein (LDL), High-density lipoprotein (HDL), triglycerides, cholesterol and glucose. Conclusively, hot red pepper (Capsicum annuum L.) inclusion up to 1.5% has the potential to improve feed conversion ratio and cost/kg weight gain, without affecting the blood biochemical indices of broiler chickens.

GCdiscrimination: identification of gastric cancer based on a milliliter of blood

2020 ◽  
Author(s):  
Jiangpeng Wu ◽  
Yifan Yang ◽  
Long Cheng ◽  
Jing Wu ◽  
Lili Xi ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Identification System ◽  
Clinical Value ◽  
Liquid Biopsies ◽  
Innovative Strategy ◽  
Blood Indices ◽  
Routine Blood ◽  
Blood Biochemical ◽  
Biochemical Indices ◽  
Blood Biochemical Indices

Abstract Gastric cancer (GC) continues to be one of the major causes of cancer deaths worldwide. Meanwhile, liquid biopsies have received extensive attention in the screening and detection of cancer along with better understanding and clinical practice of biomarkers. In this work, 58 routine blood biochemical indices were tentatively used as integrated markers, which further expanded the scope of liquid biopsies and a discrimination system for GC consisting of 17 top-ranked indices, elaborated by random forest method was constructed to assist in preliminary assessment prior to histological and gastroscopic diagnosis based on the test data of a total of 2951 samples. The selected indices are composed of eight routine blood indices (MO%, IG#, IG%, EO%, P-LCR, RDW-SD, HCT and RDW-CV) and nine blood biochemical indices (TP, AMY, GLO, CK, CHO, CK-MB, TG, ALB and γ-GGT). The system presented a robust classification performance, which can quickly distinguish GC from other stomach diseases, different cancers and healthy people with sensitivity, specificity, total accuracy and area under the curve of 0.9067, 0.9216, 0.9138 and 0.9720 for the cross-validation set, respectively. Besides, this system can not only provide an innovative strategy to facilitate rapid and real-time GC identification, but also reveal the remote correlation between GC and these routine blood biochemical parameters, which helped to unravel the hidden association of these parameters with GC and serve as the basis for subsequent studies of the clinical value in prevention program and surveillance management for GC. The identification system, called GC discrimination, is now available online at http://lishuyan.lzu.edu.cn/GC/.

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