scholarly journals Deep Learning for Laryngopharyngeal Reflux Diagnosis

2021 ◽  
Vol 11 (11) ◽  
pp. 4753
Author(s):  
Gen Ye ◽  
Chen Du ◽  
Tong Lin ◽  
Yan Yan ◽  
Jack Jiang

(1) Background: Deep learning has become ubiquitous due to its impressive performance in various domains, such as varied as computer vision, natural language and speech processing, and game-playing. In this work, we investigated the performance of recent deep learning approaches on the laryngopharyngeal reflux (LPR) diagnosis task. (2) Methods: Our dataset is composed of 114 subjects with 37 pH-positive cases and 77 control cases. In contrast to prior work based on either reflux finding score (RFS) or pH monitoring, we directly take laryngoscope images as inputs to neural networks, as laryngoscopy is the most common and simple diagnostic method. The diagnosis task is formulated as a binary classification problem. We first tested a powerful backbone network that incorporates residual modules, attention mechanism and data augmentation. Furthermore, recent methods in transfer learning and few-shot learning were investigated. (3) Results: On our dataset, the performance is the best test classification accuracy is 73.4%, while the best AUC value is 76.2%. (4) Conclusions: This study demonstrates that deep learning techniques can be applied to classify LPR images automatically. Although the number of pH-positive images used for training is limited, deep network can still be capable of learning discriminant features with the advantage of technique.

Author(s):  
Bosede Iyiade Edwards ◽  
Nosiba Hisham Osman Khougali ◽  
Adrian David Cheok

With recent focus on deep neural network architectures for development of algorithms for computer-aided diagnosis (CAD), we provide a review of studies within the last 3 years (2015-2017) reported in selected top journals and conferences. 29 studies that met our inclusion criteria were reviewed to identify trends in this field and to inform future development. Studies have focused mostly on cancer-related diseases within internal medicine while diseases within gender-/age-focused fields like gynaecology/pediatrics have not received much focus. All reviewed studies employed image datasets, mostly sourced from publicly available databases (55.2%) and few based on data from human subjects (31%) and non-medical datasets (13.8%), while CNN architecture was employed in most (70%) of the studies. Confirmation of the effect of data manipulation on quality of output and adoption of multi-class rather than binary classification also require more focus. Future studies should leverage collaborations with medical experts to aid future with actual clinical testing with reporting based on some generally applicable index to enable comparison. Our next steps on plans for CAD development for osteoarthritis (OA), with plans to consider multi-class classification and comparison across deep learning approaches and unsupervised architectures were also highlighted.


Author(s):  
Nicksson Ckayo Arrais de Freitas ◽  
Ticiana L. Coelho Da Silva ◽  
José Antônio Fernandes De Macêdo ◽  
Leopoldo Melo Júnioer

Deep learning has gained much popularity in the past years due to GPU advancements, cloud computing improvements, and its supremacy, considering the accuracy results when trained on massive datasets. As with machine learning, deep learning models may experience low performance when handled with imbalanced datasets. In this paper, we focus on the trajectory classification problem, and we examine deep learning techniques for coping with imbalanced class data. We extend a deep learning model, called DeepeST (Deep Learning for Sub-Trajectory classification), to predict the class or label for sub-trajectories from imbalanced datasets. DeepeST is the first deep learning model for trajectory classification that provides approaches for coping with imbalanced dataset problems from the authors' knowledge. In this paper, we perform the experiments with three real datasets from LBSN (Location-Based Social Network) trajectories to identify who is the user of a sub-trajectory (similar to the Trajectory-User Linking problem). We show that DeepeST outperforms other deep learning approaches from state-of-the-art concerning the accuracy, precision, recall, and F1-score.


Recently, the demand for computer vision techniques is continuously rising because of the development of techniques in decision making pertaining to health sector. Image processing is a subset of computer vision which makes use of algorithms to perform vision emulation to recognize objects. In this study a novel convolutional neural network is configured based on deep learning to classifying Chest x-ray images into five major classes. It addresses an issue of insufficiency in medical images for employing deep learning for image classification. A new augmentation technique superimposing of images helps to generate more new samples from the available images using label-preserving transformations. Data augmentation technique can generate new sample data from the original data using various transforming strategies. Therefore the data augmentation technique helps in accumulating enough data for processing to obtain better performance. The main objective of superimposing of two images is to minimize redundancy and uncertainty in the output image. Therefore the superimposing carried out with original image and a set of various augmented image to obtain better accuracy. Later results of various superimposing techniques are compared and evaluated to demonstrate the better techniques. It is concluded that the proposed techniques can obtain better performance in medical image classification problem.


Electronics ◽  
2021 ◽  
Vol 10 (13) ◽  
pp. 1550
Author(s):  
Alexandros Liapis ◽  
Evanthia Faliagka ◽  
Christos P. Antonopoulos ◽  
Georgios Keramidas ◽  
Nikolaos Voros

Physiological measurements have been widely used by researchers and practitioners in order to address the stress detection challenge. So far, various datasets for stress detection have been recorded and are available to the research community for testing and benchmarking. The majority of the stress-related available datasets have been recorded while users were exposed to intense stressors, such as songs, movie clips, major hardware/software failures, image datasets, and gaming scenarios. However, it remains an open research question if such datasets can be used for creating models that will effectively detect stress in different contexts. This paper investigates the performance of the publicly available physiological dataset named WESAD (wearable stress and affect detection) in the context of user experience (UX) evaluation. More specifically, electrodermal activity (EDA) and skin temperature (ST) signals from WESAD were used in order to train three traditional machine learning classifiers and a simple feed forward deep learning artificial neural network combining continues variables and entity embeddings. Regarding the binary classification problem (stress vs. no stress), high accuracy (up to 97.4%), for both training approaches (deep-learning, machine learning), was achieved. Regarding the stress detection effectiveness of the created models in another context, such as user experience (UX) evaluation, the results were quite impressive. More specifically, the deep-learning model achieved a rather high agreement when a user-annotated dataset was used for validation.


2021 ◽  
Vol 22 (15) ◽  
pp. 7911
Author(s):  
Eugene Lin ◽  
Chieh-Hsin Lin ◽  
Hsien-Yuan Lane

A growing body of evidence currently proposes that deep learning approaches can serve as an essential cornerstone for the diagnosis and prediction of Alzheimer’s disease (AD). In light of the latest advancements in neuroimaging and genomics, numerous deep learning models are being exploited to distinguish AD from normal controls and/or to distinguish AD from mild cognitive impairment in recent research studies. In this review, we focus on the latest developments for AD prediction using deep learning techniques in cooperation with the principles of neuroimaging and genomics. First, we narrate various investigations that make use of deep learning algorithms to establish AD prediction using genomics or neuroimaging data. Particularly, we delineate relevant integrative neuroimaging genomics investigations that leverage deep learning methods to forecast AD on the basis of incorporating both neuroimaging and genomics data. Moreover, we outline the limitations as regards to the recent AD investigations of deep learning with neuroimaging and genomics. Finally, we depict a discussion of challenges and directions for future research. The main novelty of this work is that we summarize the major points of these investigations and scrutinize the similarities and differences among these investigations.


Author(s):  
S. Prasanthi ◽  
S.Durga Bhavani ◽  
T. Sobha Rani ◽  
Raju S. Bapi

Vast majority of successful drugs or inhibitors achieve their activity by binding to, and modifying the activity of a protein leading to the concept of druggability. A target protein is druggable if it has the potential to bind the drug-like molecules. Hence kinase inhibitors need to be studied to understand the specificity of a kinase inhibitor in choosing a particular kinase target. In this paper we focus on human kinase drug target sequences since kinases are known to be potential drug targets. Also we do a preliminary analysis of kinase inhibitors in order to study the problem in the protein-ligand space in future. The identification of druggable kinases is treated as a classification problem in which druggable kinases are taken as positive data set and non-druggable kinases are chosen as negative data set. The classification problem is addressed using machine learning techniques like support vector machine (SVM) and decision tree (DT) and using sequence-specific features. One of the challenges of this classification problem is due to the unbalanced data with only 48 druggable kinases available against 509 non-drugggable kinases present at Uniprot. The accuracy of the decision tree classifier obtained is 57.65 which is not satisfactory. A two-tier architecture of decision trees is carefully designed such that recognition on the non-druggable dataset also gets improved. Thus the overall model is shown to achieve a final performance accuracy of 88.37. To the best of our knowledge, kinase druggability prediction using machine learning approaches has not been reported in literature.


2022 ◽  
pp. 27-50
Author(s):  
Rajalaxmi Prabhu B. ◽  
Seema S.

A lot of user-generated data is available these days from huge platforms, blogs, websites, and other review sites. These data are usually unstructured. Analyzing sentiments from these data automatically is considered an important challenge. Several machine learning algorithms are implemented to check the opinions from large data sets. A lot of research has been undergone in understanding machine learning approaches to analyze sentiments. Machine learning mainly depends on the data required for model building, and hence, suitable feature exactions techniques also need to be carried. In this chapter, several deep learning approaches, its challenges, and future issues will be addressed. Deep learning techniques are considered important in predicting the sentiments of users. This chapter aims to analyze the deep-learning techniques for predicting sentiments and understanding the importance of several approaches for mining opinions and determining sentiment polarity.


IoT ◽  
2020 ◽  
Vol 1 (2) ◽  
pp. 551-604
Author(s):  
Damien Warren Fernando ◽  
Nikos Komninos ◽  
Thomas Chen

This survey investigates the contributions of research into the detection of ransomware malware using machine learning and deep learning algorithms. The main motivations for this study are the destructive nature of ransomware, the difficulty of reversing a ransomware infection, and how important it is to detect it before infecting a system. Machine learning is coming to the forefront of combatting ransomware, so we attempted to identify weaknesses in machine learning approaches and how they can be strengthened. The threat posed by ransomware is exceptionally high, with new variants and families continually being found on the internet and dark web. Recovering from ransomware infections is difficult, given the nature of the encryption schemes used by them. The increase in the use of artificial intelligence also coincides with this boom in ransomware. The exploration into machine learning and deep learning approaches when it comes to detecting ransomware poses high interest because machine learning and deep learning can detect zero-day threats. These techniques can generate predictive models that can learn the behaviour of ransomware and use this knowledge to detect variants and families which have not yet been seen. In this survey, we review prominent research studies which all showcase a machine learning or deep learning approach when detecting ransomware malware. These studies were chosen based on the number of citations they had by other research. We carried out experiments to investigate how the discussed research studies are impacted by malware evolution. We also explored the new directions of ransomware and how we expect it to evolve in the coming years, such as expansion into IoT (Internet of Things), with IoT being integrated more into infrastructures and into homes.


Sensors ◽  
2020 ◽  
Vol 20 (10) ◽  
pp. 2984
Author(s):  
Yue Mu ◽  
Tai-Shen Chen ◽  
Seishi Ninomiya ◽  
Wei Guo

Automatic detection of intact tomatoes on plants is highly expected for low-cost and optimal management in tomato farming. Mature tomato detection has been wildly studied, while immature tomato detection, especially when occluded with leaves, is difficult to perform using traditional image analysis, which is more important for long-term yield prediction. Therefore, tomato detection that can generalize well in real tomato cultivation scenes and is robust to issues such as fruit occlusion and variable lighting conditions is highly desired. In this study, we build a tomato detection model to automatically detect intact green tomatoes regardless of occlusions or fruit growth stage using deep learning approaches. The tomato detection model used faster region-based convolutional neural network (R-CNN) with Resnet-101 and transfer learned from the Common Objects in Context (COCO) dataset. The detection on test dataset achieved high average precision of 87.83% (intersection over union ≥ 0.5) and showed a high accuracy of tomato counting (R2 = 0.87). In addition, all the detected boxes were merged into one image to compile the tomato location map and estimate their size along one row in the greenhouse. By tomato detection, counting, location and size estimation, this method shows great potential for ripeness and yield prediction.


2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Okeke Stephen ◽  
Mangal Sain ◽  
Uchenna Joseph Maduh ◽  
Do-Un Jeong

This study proposes a convolutional neural network model trained from scratch to classify and detect the presence of pneumonia from a collection of chest X-ray image samples. Unlike other methods that rely solely on transfer learning approaches or traditional handcrafted techniques to achieve a remarkable classification performance, we constructed a convolutional neural network model from scratch to extract features from a given chest X-ray image and classify it to determine if a person is infected with pneumonia. This model could help mitigate the reliability and interpretability challenges often faced when dealing with medical imagery. Unlike other deep learning classification tasks with sufficient image repository, it is difficult to obtain a large amount of pneumonia dataset for this classification task; therefore, we deployed several data augmentation algorithms to improve the validation and classification accuracy of the CNN model and achieved remarkable validation accuracy.


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