scholarly journals DeepFMD: Computational Analysis for Malaria Detection in Blood-Smear Images Using Deep-Learning Features

2021 ◽  
Vol 4 (4) ◽  
pp. 82
Author(s):  
Aliyu Abubakar ◽  
Mohammed Ajuji ◽  
Ibrahim Usman Yahya

Malaria is one of the most infectious diseases in the world, particularly in developing continents such as Africa and Asia. Due to the high number of cases and lack of sufficient diagnostic facilities and experienced medical personnel, there is a need for advanced diagnostic procedures to complement existing methods. For this reason, this study proposes the use of machine-learning models to detect the malaria parasite in blood-smear images. Six different features—VGG16, VGG19, ResNet50, ResNet101, DenseNet121, and DenseNet201 models—were extracted. Then Decision Tree, Support Vector Machine, Naïve Bayes, and K-Nearest Neighbour classifiers were trained using these six features. Extensive performance analysis is presented in terms of precision, recall, f-1score, accuracy, and computational time. The results showed that automating the process can effectively detect the malaria parasite in blood samples with an accuracy of over 94% with less complexity than the previous approaches found in the literature.

2018 ◽  
Vol 24 (15) ◽  
pp. 1652-1675 ◽  
Author(s):  
Kamil Zalewski ◽  
Malgorzata Benke ◽  
Bartlomiej Mirocha ◽  
Jakub Radziszewski ◽  
Magdalena Chechlinska ◽  
...  

Technetium (99mTc)-radiolabeled colloids are popular tracers used to map lymphatic vessels and regional lymph nodes (LNs). The regional LN status is a significant determinant of cancer stage and patient prognosis, and strongly influences treatment. Regional LN dissection has become a part of surgical treatment. However, not all patients with LN involvement benefit from extensive lymphadenectomy in terms of prolonged survival. Moreover, overtreatment of patients with localized disease carries the unnecessary risk of complications. It is believed that sentinel LN biopsy (SLNB) allows to assess the involvement of the most representative LN of the lymphatic basin and to decide on radical LN dissection.99mTc is an easily available radionuclide emitting gamma rays. The value of 99mTc for diagnostic procedures is associated with its relatively short half-life that makes it safe both for patients and medical personnel. A colloid presenting specific physical and biological properties, including optimal particle size, is a carrier for the radionuclide. When administered at the tumor site, a radiocolloid is absorbed by the lymphatics, and the first LN that it gets trapped in is referred to as the sentinel LN (SLN). The radiopharmaceutical must reach the SLN relatively quickly, but its storage within the SLN, and the radionuclide’s half-life must be long enough to enable intraoperative imaging and evaluation. SLNB is currently the gold standard in breast cancer and malignant melanoma diagnosis, and is under extensive investigation in gynecological cancers. Here, we provide a historical perspective of the SLN concept and the clinical relevance of SLNB in gynecologic oncology. Moreover, we review the technical aspects of the application of 99mTc-based radiopharmaceuticals in lymphoscintigraphy and intraoperative lymphatic mapping.


2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Fetulhak Abdurahman ◽  
Kinde Anlay Fante ◽  
Mohammed Aliy

Abstract Background Manual microscopic examination of Leishman/Giemsa stained thin and thick blood smear is still the “gold standard” for malaria diagnosis. One of the drawbacks of this method is that its accuracy, consistency, and diagnosis speed depend on microscopists’ diagnostic and technical skills. It is difficult to get highly skilled microscopists in remote areas of developing countries. To alleviate this problem, in this paper, we propose to investigate state-of-the-art one-stage and two-stage object detection algorithms for automated malaria parasite screening from microscopic image of thick blood slides. Results YOLOV3 and YOLOV4 models, which are state-of-the-art object detectors in accuracy and speed, are not optimized for detecting small objects such as malaria parasites in microscopic images. We modify these models by increasing feature scale and adding more detection layers to enhance their capability of detecting small objects without notably decreasing detection speed. We propose one modified YOLOV4 model, called YOLOV4-MOD and two modified models of YOLOV3, which are called YOLOV3-MOD1 and YOLOV3-MOD2. Besides, new anchor box sizes are generated using K-means clustering algorithm to exploit the potential of these models in small object detection. The performance of the modified YOLOV3 and YOLOV4 models were evaluated on a publicly available malaria dataset. These models have achieved state-of-the-art accuracy by exceeding performance of their original versions, Faster R-CNN, and SSD in terms of mean average precision (mAP), recall, precision, F1 score, and average IOU. YOLOV4-MOD has achieved the best detection accuracy among all the other models with a mAP of 96.32%. YOLOV3-MOD2 and YOLOV3-MOD1 have achieved mAP of 96.14% and 95.46%, respectively. Conclusions The experimental results of this study demonstrate that performance of modified YOLOV3 and YOLOV4 models are highly promising for detecting malaria parasites from images captured by a smartphone camera over the microscope eyepiece. The proposed system is suitable for deployment in low-resource setting areas.


2015 ◽  
Vol 39 (10) ◽  
Author(s):  
Meng-Hsiun Tsai ◽  
Shyr-Shen Yu ◽  
Yung-Kuan Chan ◽  
Chun-Chu Jen

2020 ◽  
Vol 19 (01) ◽  
pp. 2040015
Author(s):  
Ahmad Alaiad ◽  
Hassan Najadat ◽  
Belal Mohsen ◽  
Khaled Balhaf

Background and objective: Chronic kidney disease (CKD) is one of the deadly diseases that can affect a lot of vital organs in the human body such as heart, liver, and lungs. Many individuals might be at early stage of kidney disease and not have any signs, which might lead to a sudden death. Previous research showed that early prediction of CKD is very important in the medical field for physicians’ decision-making and patients’ health and life. To this end, constructing an efficient prediction system for CKD, which is the goal of this paper, often reduces medical errors and overall healthcare cost. Methods: Classification and association rule mining techniques were integrated and utilised to construct an efficient system for predicting and diagnosing CKD and its causes using weka and SPSS as platform environments. In particular, five classification algorithms, namely, naive Bayes, decision tree, support vector machine, K-nearest neighbour, and JRip were used to achieve the research goal. In addition, Apriori algorithm was used to discover strong relationship rules between attributes. The experiments were conducted on real medical dataset collected from hospitals and patient monitoring systems. Results: The experiments achieved high accuracy of 98.50% for K-nearest neighbour (KNN) classifier and achieved 96.00% when using classier based on association rule (JRip). Conclusions: We conclude by showing that applying integrative approach by combining classification algorithms and association rule mining can significantly improve the classification accuracy and be more useful for CKD prediction. This research has also several theoretical and practical implications for the medical field and healthcare industry.


2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Md. Matiur Rahaman ◽  
Md. Asif Ahsan ◽  
Ming Chen

AbstractStatistical data-mining (DM) and machine learning (ML) are promising tools to assist in the analysis of complex dataset. In recent decades, in the precision of agricultural development, plant phenomics study is crucial for high-throughput phenotyping of local crop cultivars. Therefore, integrated or a new analytical approach is needed to deal with these phenomics data. We proposed a statistical framework for the analysis of phenomics data by integrating DM and ML methods. The most popular supervised ML methods; Linear Discriminant Analysis (LDA), Random Forest (RF), Support Vector Machine with linear (SVM-l) and radial basis (SVM-r) kernel are used for classification/prediction plant status (stress/non-stress) to validate our proposed approach. Several simulated and real plant phenotype datasets were analyzed. The results described the significant contribution of the features (selected by our proposed approach) throughout the analysis. In this study, we showed that the proposed approach removed phenotype data analysis complexity, reduced computational time of ML algorithms, and increased prediction accuracy.


PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0248064
Author(s):  
Pengshun Li ◽  
Jiarui Chang ◽  
Yi Zhang ◽  
Yi Zhang

Taxi order demand prediction is of tremendous importance for continuous upgrading of an intelligent transportation system to realise city-scale and personalised services. An accurate short-term taxi demand prediction model in both spatial and temporal relations can assist a city pre-allocate its resources and facilitate city-scale taxi operation management in a megacity. To address problems similar to the above, in this study, we proposed a multi-zone order demand prediction model to predict short-term taxi order demand in different zones at city-scale. A two-step methodology was developed, including order zone division and multi-zone order prediction. For the zone division step, the K-means++ spatial clustering algorithm was used, and its parameter k was estimated by the between–within proportion index. For the prediction step, six methods (backpropagation neural network, support vector regression, random forest, average fusion-based method, weighted fusion-based method, and k-nearest neighbour fusion-based method) were used for comparison. To demonstrate the performance, three multi-zone weighted accuracy indictors were proposed to evaluate the order prediction ability at city-scale. These models were implemented and validated on real-world taxi order demand data from a three-month consecutive collection in Shenzhen, China. Experiment on the city-scale taxi demand data demonstrated the superior prediction performance of the multi-zone order demand prediction model with the k-nearest neighbour fusion-based method based on the proposed accuracy indicator.


2021 ◽  
Author(s):  
Praveeen Anandhanathan ◽  
Priyanka Gopalan

Abstract Coronavirus disease (COVID-19) is spreading across the world. Since at first it has appeared in Wuhan, China in December 2019, it has become a serious issue across the globe. There are no accurate resources to predict and find the disease. So, by knowing the past patients’ records, it could guide the clinicians to fight against the pandemic. Therefore, for the prediction of healthiness from symptoms Machine learning techniques can be implemented. From this we are going to analyse only the symptoms which occurs in every patient. These predictions can help clinicians in the easier manner to cure the patients. Already for prediction of many of the diseases, techniques like SVM (Support vector Machine), Fuzzy k-Means Clustering, Decision Tree algorithm, Random Forest Method, ANN (Artificial Neural Network), KNN (k-Nearest Neighbour), Naïve Bayes, Linear Regression model are used. As we haven’t faced this disease before, we can’t say which technique will give the maximum accuracy. So, we are going to provide an efficient result by comparing all the such algorithms in RStudio.


Deriving the methodologies to detect heart issues at an earlier stage and intimating the patient to improve their health. To resolve this problem, we will use Machine Learning techniques to predict the incidence at an earlier stage. We have a tendency to use sure parameters like age, sex, height, weight, case history, smoking and alcohol consumption and test like pressure ,cholesterol, diabetes, ECG, ECHO for prediction. In machine learning there are many algorithms which will be used to solve this issue. The algorithms include K-Nearest Neighbour, Support vector classifier, decision tree classifier, logistic regression and Random Forest classifier. Using these parameters and algorithms we need to predict whether or not the patient has heart disease or not and recommend the patient to improve his/her health.


2019 ◽  
Vol 8 (4) ◽  
pp. 2514-2519

Microarray is a fast and rapid growing technology which plays dynamic role in the medical field. It is an advanced than MRI (Magnetic Resonance Imaging) and CT scanning (Computerised Tomography). The purpose of this work is to make fine perfection against the gene expression. In this study the two clustering are used which fuzzy c means and k means and also it classifies with better results. The microarray data base indicates the classification in support vector machine. Segmentation is most important step in microarray image. The classification in support vector machine is compared with other two classifiers which means the k nearest neighbour and with the Bayes classifiers.


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