scholarly journals Polysaccharide-Based Systems for Targeted Stem Cell Differentiation and Bone Regeneration

Biomolecules ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. 840 ◽  
Author(s):  
Markus Witzler ◽  
Dominik Büchner ◽  
Sarah Shoushrah ◽  
Patrick Babczyk ◽  
Juliana Baranova ◽  
...  

Bone tissue engineering is an ever-changing, rapidly evolving, and highly interdisciplinary field of study, where scientists try to mimic natural bone structure as closely as possible in order to facilitate bone healing. New insights from cell biology, specifically from mesenchymal stem cell differentiation and signaling, lead to new approaches in bone regeneration. Novel scaffold and drug release materials based on polysaccharides gain increasing attention due to their wide availability and good biocompatibility to be used as hydrogels and/or hybrid components for drug release and tissue engineering. This article reviews the current state of the art, recent developments, and future perspectives in polysaccharide-based systems used for bone regeneration.

2019 ◽  
Vol 7 (6) ◽  
pp. 2452-2467 ◽  
Author(s):  
Shijie Liu ◽  
Yiyun Wang ◽  
Jian Wang ◽  
Pengcheng Qiu ◽  
Shengyu Wang ◽  
...  

Bone regenerative therapies have been explored using various biomaterial systems.


2015 ◽  
Vol 3 (16) ◽  
pp. 3150-3168 ◽  
Author(s):  
Sunil Kumar Boda ◽  
Greeshma Thrivikraman ◽  
Bikramjit Basu

Substrate magnetization as a tool for modulating the osteogenesis of human mesenchymal stem cells for bone tissue engineering applications.


2017 ◽  
Vol 261 ◽  
pp. 234-245 ◽  
Author(s):  
Ruixiang Li ◽  
Zhiqing Pang ◽  
Huining He ◽  
Seungjin Lee ◽  
Jing Qin ◽  
...  

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