scholarly journals Healthcare Use during the Last Six Months of Life in Patients with Advanced Breast Cancer

Cancers ◽  
2021 ◽  
Vol 13 (21) ◽  
pp. 5271
Author(s):  
Renée. S. J. M. Schmitz ◽  
Sandra. M. E. Geurts ◽  
Khava. I. E. Ibragimova ◽  
Dominique. J. P. Tilli ◽  
Vivianne C. G. Tjan-Heijnen ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Health Care ◽  
Advanced Breast Cancer ◽  
End Of Life ◽  
Medical Center ◽  
Treatment Options ◽  
Admission Rate ◽  
Health Care Use ◽  
Advanced Breast ◽  
Hospital Admission Rate

New treatment options in cancer have resulted in increased use of health care resources near the end of life. We assessed health care use near the end of life of patients with advanced breast cancer (ABC). From the Southeast Netherlands Breast cancer (SONABRE) registry, we selected all deceased patients diagnosed with ABC in Maastricht University Medical Center between January 2007 and October 2017. Frequency of health care use in the last six months of life was described and predictors for health care use were assessed. Of 203 patients, 76% were admitted during the last six months, 6% to the intensive care unit (ICU) and 2% underwent cardiopulmonary resuscitation (CPR). Death in hospital occurred in 25%. Nine percent of patients received a new line of chemotherapy ≤30 days before death, which was associated with age <65 years and <1 year survival since diagnosis of metastases. In these patients, the hospital admission rate was 95%, of which 79% died in the hospital, mostly due to progressive disease (80%). In conclusion, the frequency of ICU-admission, CPR or a new line of chemotherapy ≤ 30 days before death was low. Most patients receiving a new line of chemotherapy ≤ 30 days before death, died in the hospital.

Demonstrating Higher Incidence of Advanced Breast Malignancies in Our Young Hispanic Population

2018 ◽  
Vol 84 (11) ◽  
pp. 1787-1789
Author(s):  
Amanda Klein ◽  
Michael Villareal ◽  
Sepeadeh Radpour ◽  
Boone Goodgame ◽  
Sadia Ali ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Health Care ◽  
Advanced Breast Cancer ◽  
Cancer Patients ◽  
Advanced Breast ◽  
Hispanic Population ◽  
Breast Cancer Patients ◽  
Advanced Malignancies ◽  
Hispanic Patients ◽  
Breast Malignancies

Historically, the Hispanic population in the United States has had a lower incidence of cancer than the matched non-Hispanic population, despite disparities in access to health care, screening, and prevention. Our experience in Austin, Texas, directly contradicts this. We have seen a disproportionate amount of young Hispanic patients with advanced malignancies, particularly of the breast. The aim of this study was to compare the incidence of advanced breast malignancies. We performed a retrospective review over a 10-year period (2003–2013) of all newly diagnosed breast cancer patients. Data were collected from the cancer registry. Patients were divided into two groups: Hispanic versus non-Hispanic descent, with a subgroup of those aged less than 50 years. Primary outcome was the incidence of advanced cancers (stage 3 or 4). There were a total of 3968 breast cancer patients seen in our Shivers Cancer Center from 2003 to 2013, with an overall incidence of advanced breast cancer of 11.5 per cent. Of the patients aged less than 50 years, 14.2 per cent had advanced breast cancer. However, the rate among Hispanic patients was 21.3 per cent, whereas in non-Hispanic patients it was 13.5 per cent, P = 0.002. Being Hispanic was found to be an independent predictor of having advanced malignancies at a young age (odds ratio 1.7, confidence interval 1.1–2.5, P = 0.01). Here in Austin, Texas, we have found a higher overall incidence of breast cancer among young Hispanic women. This is important to recognize because more efforts may be required to increase screening and health-care access to this population.

Understanding potential communication gaps between oncologists and patients with advanced breast cancer: A survey of oncologists.

2014 ◽  
Vol 32 (26_suppl) ◽  
pp. 124-124
Author(s):  
Adam Brufsky ◽  
Marc L. Citron ◽  
Deana Percassi
Keyword(s):  
Breast Cancer ◽  
Advanced Breast Cancer ◽  
Online Survey ◽  
Treatment Options ◽  
Geographic Region ◽  
Advanced Breast ◽  
Emotional Impact ◽  
Cancer Symptoms ◽  
Related Information ◽  
Survey Results

124 Background: About 232,670 cases of breast cancer will be diagnosed in the US in 2014, of which 86,088 (37%) will be metastatic advanced breast cancer (ABC). The 2013 Global Count Us, Know Us, Join Us survey found that 53% of US women with ABC wanted more time to discuss their needs during clinic visits, and 60% believe their cancer treatment options are limited. To better understand unmet patient needs and potential communication gaps with physicians, surveys were developed for women with ABC, their caregivers, and oncologists. The oncologists’ survey results are presented. Methods: The Make Your Dialogue Count survey for oncologists has 32 items. Responses are single or multiple response numeric text or rated on a 4-point Likert scale. Harris Poll conducted this online survey from June through July 2014 among randomly selected, licensed US medical oncologists who treat ≥ 5 women with ABC per month. Responses for geographic region and number of years in practice by sex were weighted to match actual proportions in the population. Results: By July 15, 2014, 228 oncologists responded. At initial diagnosis, showing care and compassion was very important to 79% of oncologists; helping patients cope with diagnosis (62%) and manage cancer symptoms (56%) and discussing expected treatment response (57%) and side effects (51%) were also very important. Most oncologists (88%) revealed that treating women with ABC has a negative emotional toll. Although 81% of oncologists believe it to be unprofessional to let their emotion affect treatment recommendations, 26% reported that their emotions kept them from providing some information. Notably, 31% of oncologists reported that in certain situations, they have not discussed with patients that ABC is incurable. Conclusions: Caring for terminally ill patients has an emotional impact on oncologists. For some, their emotions have influenced what treatments they recommend and what information they impart. Our findings show that oncologists are compassionate and share disease- and treatment-related information and highlight the need to develop communication strategies that facilitate exchange between oncologists and their patients with ABC.

scholarly journals Morphological features of tumor in different treatment options for patients With Locally Advanced Breast Cancer

2020 ◽  
Vol 1 (7) ◽  
pp. 105-107
Author(s):  
Narzieyva D.F ◽  
Jonibekov J.J ◽  
Erkinova Sh.N
Keyword(s):  
Breast Cancer ◽  
Advanced Breast Cancer ◽  
Locally Advanced Breast Cancer ◽  
Treatment Options ◽  
Molecular Genetic ◽  
Locally Advanced ◽  
Morphological Structure ◽  
Advanced Breast ◽  
Ki 67 ◽  
The Republic

Despite significant advances in the early diagnosis and treatment of locally advanced breast cancer, 60–65% of the Republic of Uzbekistan is accounted for by locally advanced breast cancer and its mortality rate is high. The morphological structure of breast cancer is important for the prognosis of the disease. On cell membranes there are special cytoplasmic proteins - receptors, which, when combined with hormones, can affect the rate of division of tumor cells. In terms of the choice of treatment options and the assessment of the forecast, some molecular genetic parameters of the tumor are important, among which, first of all, the hormonal status of the tumor (ER / PR), HER-2 / neu, p53, Bcl-2, Ki-67

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