scholarly journals Modern Management of Esophageal Cancer: Radio-Oncology in Neoadjuvancy, Adjuvancy and Palliation

Cancers ◽  
2022 ◽  
Vol 14 (2) ◽  
pp. 431
Author(s):  
Francesco Cellini ◽  
Stefania Manfrida ◽  
Calogero Casà ◽  
Angela Romano ◽  
Alessandra Arcelli ◽  
...  

The modern management of esophageal cancer is crucially based on a multidisciplinary and multimodal approach. Radiotherapy is involved in neoadjuvant and adjuvant settings; moreover, it includes radical and palliative treatment intention (with a focus on the use of a stent and its potential integration with radiotherapy). In this review, the above-mentioned settings and approaches will be described. Referring to available international guidelines, the background evidence bases will be reviewed, and the ongoing, more relevant trials will be outlined. Target definitions and radiotherapy doses to administer will be mentioned. Peculiar applications such as brachytherapy (interventional radiation oncology), and data regarding innovative approaches including MRI-guided-RT and radiomic analysis will be reported. A focus on the avoidance of surgery for major clinical responses (particularly for SCC) is detailed.

2017 ◽  
Vol 63 (4) ◽  
pp. 660-665
Author(s):  
Yelena Tyuryaeva

The article is devoted to various aspects of the use of intraluminal brachytherapy (IB) in treatment for esophageal cancer (EC). A critical review of the use of IB as a component of combined radiotherapy/chemoradiotherapy in neoadjuvant treatment regimens, for definitive CRT, as well as in palliative treatment of non-operable tumors of this localization is given. The contradictory data on the effectiveness of brachytherapy with locally distributed, inoperable EC are summarized. A separate section relates to the prospects for incorporating brachytherapy into combined treatment of early esophageal cancer. Carried out analysis testifies to the necessity of standardization of summary and daily doses of irradiation depending on the indications to the IB.


Author(s):  
Eric A. Harris ◽  
Keith Candiotti

Cancer continues to be a leading cause of death in the developed world, with physicians and scientists constantly devising new weapons to combat it. Chemotherapy, surgery, nutrition, and holistic medicine all have a place in the multimodal approach that can prolong longevity and ameliorate quality of life. As part of this armamentarium, radiation therapy (XRT) has proven to be a safe and effective technique for the management of various malignant (and occasionally nonmalignant) lesions. XRT can be used for both curative and palliative purposes; in the latter case, patients benefit from decreased pain, preserved organ function, and the maintenance of lumen patency in hollow organs.1 The medical team, led by a radiation oncologist, often includes a physicist, a dosimetrist, several radiation therapists (technologists), and the patient’s primary care physician.2 Anesthesiologists are increasingly being asked to join this team, as our services are recognized as a vital component for patient safety and comfort.


2020 ◽  
Vol 147 ◽  
pp. 1-7 ◽  
Author(s):  
M.R. Boekhoff ◽  
I.L. Defize ◽  
A.S. Borggreve ◽  
N. Takahashi ◽  
A.L.H.M.W. van Lier ◽  
...  

1994 ◽  
Vol 4 (3) ◽  
pp. 202-214 ◽  
Author(s):  
Neelofur R. Ahmad ◽  
Eric B. Goosenberg ◽  
Harold Frucht ◽  
Lawrence R. Coia

ORL ◽  
1968 ◽  
Vol 30 (1) ◽  
pp. 35-44
Author(s):  
T. Palva ◽  
E. Heikkinen ◽  
T.K.I. Larmi

Brachytherapy ◽  
2007 ◽  
Vol 6 (2) ◽  
pp. 116
Author(s):  
Janusz Skowronek ◽  
Marek Kanikowski ◽  
Janusz Wasiewicz ◽  
Adam Chichel ◽  
Magda Kubaszewska

Sign in / Sign up

Export Citation Format

Share Document