scholarly journals Biophysical and Subject-Based Assessment of the Effects of Topical Moisturizer Usage on Xerotic Skin—Part I: EpsilonTM 2D Skin Hydration

Cosmetics ◽  
2021 ◽  
Vol 9 (1) ◽  
pp. 6
Author(s):  
Hans Stettler ◽  
Jonathan Crowther ◽  
Alison Boxshall ◽  
Stephan Bielfeldt ◽  
Bailu Lu ◽  
...  
Keyword(s):  
Measurement Data ◽  
Skin Condition ◽  
Skin Hydration ◽  
Two Dimensional ◽  
Electrical Characteristics ◽  
Single Number ◽  
Electrical Permittivity ◽  
Feedback Data ◽  
Electrical Skin

As new biophysical methods become available to the skin researcher, it is important to understand the type of information that they are capable of measuring, and how it relates to consumer perception of topical moisturizing products. This work was aimed at understanding how two-dimensional (2D) skin hydration mapping can be used to describe skin properties beyond the traditional ‘single number’ approach to skin hydration. Two-dimensional skin hydration measurement data were collected at baseline and after 1 week of in vivo usage of a topical moisturizing product. In addition, subject feedback regarding their skin condition obtained during the study was collected and assessed. Dividing the 2D hydration measurement device images into zones of different electrical permittivity scores enabled analysis of different aspects of the skin compared with traditional electrical skin hydration measurements. Improvement in skin flexibility as a result of use of the topical test product was demonstrated. Complete description of the skin’s hydration state through the creation of hydration histograms to describe its electrical characteristics was performed. Subject feedback data showed improvements in aspects of skin assessed using 2D hydration measurement.

Specific Labeling of Protein Domains with Antibody Fragments

1981 ◽  
Vol 39 ◽  
pp. 416-417
Author(s):  
U. Aebi ◽  
L.E. Buhle ◽  
W.E. Fowler
Keyword(s):  
Image Processing ◽  
Specific Protein ◽  
Antibody Fragments ◽  
Supramolecular Organization ◽  
Two Dimensional ◽  
Ordered Structures ◽  
Virus Capsids ◽  
Processing Techniques

Many important supramolecular structures such as filaments, microtubules, virus capsids and certain membrane proteins and bacterial cell walls exist as ordered polymers or two-dimensional crystalline arrays in vivo. In several instances it has been possible to induce soluble proteins to form ordered polymers or two-dimensional crystalline arrays in vitro. In both cases a combination of electron microscopy of negatively stained specimens with analog or digital image processing techniques has proven extremely useful for elucidating the molecular and supramolecular organization of the constituent proteins. However from the reconstructed stain exclusion patterns it is often difficult to identify distinct stain excluding regions with specific protein subunits. To this end it has been demonstrated that in some cases this ambiguity can be resolved by a combination of stoichiometric labeling of the ordered structures with subunit-specific antibody fragments (e.g. Fab) and image processing of the electron micrographs recorded from labeled and unlabeled structures.

A Novel Junction Profiling Methodology

2010 ◽  
Author(s):  
Tomokazu Nakai
Keyword(s):  
Failure Analysis ◽  
Profile Analysis ◽  
Semiconductor Devices ◽  
Wet Etching ◽  
Two Dimensional ◽  
Electrical Characteristics ◽  
Conventional Methods

Abstract Currently many methods are available to obtain a junction profile of semiconductor devices, but the conventional methods have drawbacks, and they could be obstacles for junction profile analysis. This paper introduces an anodic wet etching-based two-dimensional junction profiling method, which is practical, efficient, and reliable for failure analysis and electrical characteristics evaluation.

scholarly journals Towards planning of osteotomy around the knee with quantitative inclusion of the adduction moment: a biomechanical approach

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Margit Biehl ◽  
Philipp Damm ◽  
Adam Trepczynski ◽  
Stefan Preiss ◽  
Gian Max Salzmann
Keyword(s):  
Gait Analysis ◽  
Measurement Data ◽  
Frontal Plane ◽  
Medial Compartment ◽  
Knee Adduction Moment ◽  
In Vivo Measurement ◽  
Force Ratio ◽  
Leg Alignment ◽  
Alignment Angle

Abstract Purpose Despite practised for decades, the planning of osteotomy around the knee, commonly using the Mikulicz-Line, is only empirically based, clinical outcome inconsistent and the target angle still controversial. A better target than the angle of frontal-plane static leg alignment might be the external frontal-plane lever arm (EFL) of the knee adduction moment. Hypothetically assessable from frontal-plane-radiograph skeleton dimensions, it might depend on the leg-alignment angle, the hip-centre-to-hip-centre distance, the femur- and tibia-length. Methods The target EFL to achieve a medial compartment force ratio of 50% during level-walking was identified by relating in-vivo-measurement data of knee-internal loads from nine subjects with instrumented prostheses to the same subjects’ EFLs computed from frontal-plane skeleton dimensions. Adduction moments derived from these calculated EFLs were compared to the subjects’ adduction moments measured during gait analysis. Results Highly significant relationships (0.88 ≤ R2 ≤ 0.90) were found for both the peak adduction moment measured during gait analysis and the medial compartment force ratio measured in vivo to EFL calculated from frontal-plane skeleton dimensions. Both correlations exceed the respective correlations with the leg alignment angle, EFL even predicts the adduction moment’s first peak. The guideline EFL for planning osteotomy was identified to 0.349 times the epicondyle distance, hence deducing formulas for individualized target angles and Mikulicz-Line positions based on full-leg radiograph skeleton dimensions. Applied to realistic skeleton geometries, widespread results explain the inconsistency regarding correction recommendations, whereas results for average geometries exactly meet the most-consented “Fujisawa-Point”. Conclusion Osteotomy outcome might be improved by planning re-alignment based on the provided formulas exploiting full-leg-radiograph skeleton dimensions.

Reformatted method for two-dimensional detector arrays measurement data in proton pencil beam scanning

2021 ◽  
Vol 32 (6) ◽  
Author(s):  
Meng-Ya Guo ◽  
Xiu-Fang Li ◽  
Jie Wang ◽  
Qi Liu ◽  
Xiu-Zhen Deng ◽  
...  
Keyword(s):  
Measurement Data ◽  
Pencil Beam ◽  
Two Dimensional ◽  
Beam Scanning ◽  
Detector Arrays ◽  
Pencil Beam Scanning

Two-dimensional photon counting imaging and spatiotemporal characterization of ultraweak photon emission from a rat’s brain in vivo

1999 ◽  
Vol 93 (2) ◽  
pp. 163-168 ◽  
Author(s):  
Masaki Kobayashi ◽  
Motohiro Takeda ◽  
Ken-Ichi Ito ◽  
Hiroshi Kato ◽  
Humio Inaba
Keyword(s):  
Photon Emission ◽  
Photon Counting ◽  
Two Dimensional

Reactive Power Compensation for Unbalanced Fluctuating Loads by Using Two-Dimensional Space Vector and a Static Var Compensator

2014 ◽  
Vol 533 ◽  
pp. 397-400 ◽  
Author(s):  
Chi Jui Wu ◽  
Yu Wei Liu ◽  
Shou Chien Huang
Keyword(s):  
Power Factor ◽  
Reactive Power ◽  
Dimensional Space ◽  
Measurement Data ◽  
Power Source ◽  
Active Power ◽  
Two Dimensional ◽  
Static Var Compensator ◽  
Space Vector ◽  
Three Phase

To modify the power factor and balance the three-phase currents simultaneously, this paper proposes the instantaneous compensator to calculate the compensation current. The instantaneous compensator utilizes two-dimensional instantaneous space vector and setting the active power as a constant for each cycle which can improve power quality effectively. Moreover, the instantaneous compensator requires an independent power source, whose capacity can be reduce by using a static var compensator (SVC). An SVC does not interfere with the capability of the instantaneous compensator. Field measurement data were analyzed. Simulation results confirmed the feasibility of correcting the power factor and balancing load currents simultaneously using the proposed method.

scholarly journals Identification of two intermediates during processing of profilaggrin to filaggrin in neonatal mouse epidermis.

1984 ◽  
Vol 99 (4) ◽  
pp. 1372-1378 ◽  
Author(s):  
K A Resing ◽  
K A Walsh ◽  
B A Dale
Keyword(s):  
Molecular Weight ◽  
High Molecular Weight ◽  
Tandem Repeats ◽  
Peptide Mapping ◽  
Two Dimensional ◽  
Major Event ◽  
Mouse Epidermis ◽  
Cell Stage ◽  
Processing Steps

A major event in the keratinization of epidermis is the production of the histidine-rich protein filaggrin (26,000 mol wt) from its high molecular weight (greater than 350,000) phosphorylated precursor (profilaggrin). We have identified two nonphosphorylated intermediates (60,000 and 90,000 mol wt) in NaSCN extracts of epidermis from C57/Bl6 mice by in vivo pulse-chase studies. Results of peptide mapping using a two-dimensional technique suggest that these intermediates consist of either two or three copies of filaggrin domains. Each of the intermediates has been purified. The ratios of amino acids in the purified components are unusual and essentially identical. The data are discussed in terms of a precursor containing tandem repeats of similar domains. In vivo pulse-chase experiments demonstrate that the processing of the high molecular weight phosphorylated precursor involves dephosphorylation and proteolytic steps through three-domain and two-domain intermediates to filaggrin. These processing steps appear to occur as the cell goes through the transition cell stage to form a cornified cell.

The beneficial effect of Cannabis Sativa seed oil on the epidermis

2021 ◽  
Vol 01 ◽  
Author(s):  
Anna Olejnik ◽  
Aleksandra Galarda ◽  
Joanna Goscianska
Keyword(s):  
Water Loss ◽  
Seed Oil ◽  
Unsaturated Fatty Acids ◽  
Cannabis Sativa ◽  
Transepidermal Water Loss ◽  
Skin Condition ◽  
Moisture Loss ◽  
Non Invasive ◽  
Oil Formulation

Background: Cannabis Sativa seed oil has become more and more popular in cosmetic industry mainly due to the high content of antioxidants and unsaturated fatty acids that are desirable in formulations because they prevent moisture loss and reduce the occurrence of dry skin. Objective: The aim of this study was to determine the effect of Cannabis Sativa seed oil on skin parameters such as hydration and transepidermal water loss. Methods: The in vivo tests on volunteers with combination skin were performed by using non-invasive methods by using corneometer and tewameter. Results: The obtained results proved that Cannabis Sativa seed oil improved skin condition. The transepidermal water loss decreased because the lipophilic components of the oil formulation tend to form an occlusive layer on the epidermis surface. The highest increase in skin hydration was observed after one week of treatment. Conclusion: These results confirmed that Cannabis Sativa seed oil has strong moisturizing properties and can be recommended as a natural based skin conditioning agent.

In Vivo Determination of Moisturizers Efficacy on Human Skin Hydration by Confocal Raman Spectroscopy

2018 ◽  
Vol 19 (7) ◽  
pp. 3177-3186 ◽  
Author(s):  
Vamshi Krishna Tippavajhala ◽  
Taciana D. Magrini ◽  
Daniele C. Matsuo ◽  
Michely G. P. Silva ◽  
Priscila P. Favero ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Human Skin ◽  
Skin Hydration ◽  
Confocal Raman Spectroscopy ◽  
Confocal Raman
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