scholarly journals The Role of Cations of the Precipitant in the Interaction of Protein Molecules in the Lysozyme Oligomers in Crystallization Solutions

Crystals ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 1534
Author(s):  
Yuliya V. Kordonskaya ◽  
Vladimir I. Timofeev ◽  
Yulia A. Dyakova ◽  
Margarita A. Marchenkova ◽  
Yury V. Pisarevsky ◽  
...  
Keyword(s):  
Protein Crystallization ◽  
Structural Transformations ◽  
Atomic Mass ◽  
Crystal Formation ◽  
Noticeable Effect ◽  
Protein Molecules ◽  
The Stability ◽  
The Moment ◽  
Dynamics Method

At the moment, the main opinion is that protein crystallization depends mainly on the the precipitant anions, therefore, there have been only few works devoted to the problem of the influence of its cations. Using the molecular dynamics method, we investigated the stability, changes in the compactness and structural transformations of lysozyme dimers and octamers in solutions with different precipitants (LiCl, NaCl, KCl and CuCl2) in order to study the contribution of cations during crystal formation in more detail. As a result, we found that cations have a rather noticeable effect on the behavior of oligomers: the higher the atomic mass of the cation, the greater the changes in the dimers structures during its dynamics and, according to the data of SAXS experiments, the lower the concentration of dimers. However, for octamers, this dependence is more complicated.

Stabilisation of Aragonite: The Role of Mg2+ and Other Impurity Ions

2019 ◽  
Author(s):  
Matthew Boon ◽  
William Rickard ◽  
Andrew Rohl ◽  
Franca Jones
Keyword(s):  
Electron Backscatter Diffraction ◽  
Crystal Formation ◽  
Sulfate Ions ◽  
Inorganic Systems ◽  
Sodium Magnesium ◽  
Stable Product ◽  
The Stability ◽  
Backscatter Diffraction ◽  
First Time

Aragonite formation and stabilisation in seawater is still an area of active investigation since the thermodynamically stable product at room temperature is calcite. In this manuscript, purely inorganic systems that were found to stabilise aragonite were analysed by various techniques. Dynamic Light Scattering was used to characterise the nucleation behaviour of the system and it was found that the presence of magnesium ions during crystal formation inhibits nucleation overall, not just calcite nucleation. In addition, it was found that sulfate is not necessary to stabilise aragonite. Microanalysis by energy dispersive X-ray spectroscopy (EDS) and electron backscatter diffraction (EBSD) revealed that the aragonite that was formed had a disordered core with, sodium, magnesium and sulfate ions incorporated into the structure. To the best of the authors’ knowledge this is the first time an ACC core in aragonite has been visualised in a completely abiotic, synthetic system (in the absence of organic molecules). Inclusion of these impurities into the structure may explain the stability of aragonite in natural seawaters.

scholarly journals The effect of microstructure of the surface, the design and dimension of dental implants on their stability and the process of osteointegration during immediate and delayed implantation. PartII

2021 ◽  
Vol 108 (4) ◽  
pp. 34-38
Author(s):  
P. Grishin ◽  
◽  
E. Mamaeva ◽  
E. Kalinnikova ◽  
A. Kozlov ◽  
...  
Keyword(s):  
Primary Stability ◽  
Implant Surface ◽  
Surface Design ◽  
Resonance Analysis ◽  
Delayed Implantation ◽  
Size Type ◽  
The Stability ◽  
The Moment ◽  
Immediate Implantation

Abstract. This article presents the results of a clinical study of the stability and process of osteointegration implants of 11 known implant dental systems. The effect of the microstructure of 3 types of implant surface (HSTTM, SLA and RBM) and their design features (shape, size, type of carving) on the indicators of their stability and osteointegration process during immediate and delayed implantation with immediate functional load is shown and analyzed. The stability of the implants and the dynamics of the quality of osteointegration were determined by the devices «Osstell Mentor» and «Periotest» in the process of treatment, starting from the moment of implant installation in different eras (2 weeks, 1 month, 2 months and 3 months). 414 patients between the ages of 20 and 70 were monitored. Of these, there are 249 and 165 male women. The average age of the operated patients was: for men – 54 years for women – 49 years. All patients were divided into two groups of the first – 109 patients who after extraction were directly implanted into the hole of the remote tooth with the subsequent immediate load, the second group – 305 patients who were delayed implantation with immediate load. A total of 1,302 implants were installed. The study revealed a link between the type of surface of the implant, primary stability and the time of its osteointegration during certain periods of clinical observation. The results of the study demonstrated the important role of combining microstructure of the surface, design and dimension features, the type of insertion of implants on their primary stability and the process of osteointegration in the conduct of both immediate and delayed implantation. Key words: frequency resonance analysis, damping, stability, osteointegration, fixation, implants, periotestometry, immediate implantation.

scholarly journals Reminiscing and the Passage of Years: Investigating the Role of Affective Autobiographical Memories in Passage of Time Judgments

2021 ◽  
Vol 12 ◽  
Author(s):  
Ferdinand Kosak ◽  
Christof Kuhbandner
Keyword(s):  
Negative Events ◽  
Autobiographical Memories ◽  
Experience Of Time ◽  
The Stability ◽  
The Moment ◽  
Affective Intensity ◽  
Positive Memories ◽  
Negative Memories ◽  
Contextual Change

Previous research has shown that judgments of the experienced velocity of recent years passing by vary depending on the number of autobiographical memories being activated in the moment of judging. While a body of evidence shows affect to have an impact on both prospective and retrospective judgments on the experience of time for short periods, the effect of valence of memories on the experience of the passage of long intervals has not been examined yet. Thus, we asked 282 people to retrieve five either emotionally positive or negative memories from the last 5years before judging the subjectively experienced passage of time of these years. However, positive and negative events differ in some ways beyond valence, e.g., the ascribed impact on the participants’ subsequent lives as well as the stability of ascribed affective intensity: The latter decreased over time for negative but not for positive memories while ascribed impact was markedly higher for positive memories. Results indicate no significant differences between the two conditions, even after controlling for the aforementioned differences. However, exploratory analyses show that participants rate time to have passed faster, the longer the activated memories dated back on average, a result that seems in line with contextual-change hypothesis.

scholarly journals Nullity of Administrative Acts: Grounds, Legal Regime, Discretion

2021 ◽  
Vol 18 (2) ◽  
pp. 228-242
Author(s):  
O. N. Sherstoboev
Keyword(s):  
Legal Doctrine ◽  
Judicial Practice ◽  
Legal Method ◽  
Administrative Procedures ◽  
Legitimate Expectations ◽  
Administrative Act ◽  
The Stability ◽  
The Moment ◽  
Legal Concepts

The issues of criteria for the nullity of administrative acts are considered, the ratio of an illegal and invalid act, as well as a null and void act, analyzed, the possibility of administrative discretion in determining an invalid administrative act is analyzed, the role of vague legal concepts when an administrative act is declared invalid is demonstrated. The Author uses a comparative legal method, including the analysis of the practice of Germany, Great Britain, South Africa, Canada, Japan, South Korea, Russia and other countries. Special attention is paid to the laws on administrative procedures adopted in the post-Soviet territory and the influence of the German doctrine on this process. It is concluded that for the continental legal order the most preferable way to formalize the criteria for the invalidity of an administrative act are laws on administrative procedures or their analogs, while in the common law states, legal doctrine and judicial practice are of great importance. At the same time, many countries avoid recognizing acts as null and void, preferring the construction of their voidability. This is related to ensuring the stability of public administration, the predictability of administrative activities, and the protection of legitimate expectations. In any case, the theory of the reality of the administrative act is prevailing, and nullity is rather viewed as an anomaly. Therefore, only acts that are adopted with the most significant violations, which do not allow talking about the fair consequences of their adoption, are considered invalid. The illegality of an act does not automatically entail its nullity. A similar trend can be traced in Russia, although individual norms of law and practice of courts indicate the possible formation of a doctrine of the invalidity of an administrative act in the Russian legal system. Insignificant acts do not give rise to consequences from the moment of their adoption, legally they do not exist, and nothing can generate anything. With this approach, the courts only fix the criterion of invalidity without a dispute about law. Insignificant acts should be distinguished from contested ones, the latter may turn out to be illegal, but for a number of reasons (for example, protection of trust) the fact of their existence is confirmed along with their consequences.

scholarly journals The effect of microstructure of the surface, the design and dimension of dental implants on their stability and the process of osteointegration during immediate and delayed implantation

2021 ◽  
Vol 107 (3) ◽  
pp. 58-63
Author(s):  
P. Grishin ◽  
◽  
E. Mamaeva ◽  
E. Kalinnikova ◽  
A. Kozlov ◽  
...  
Keyword(s):  
Primary Stability ◽  
Implant Surface ◽  
Surface Design ◽  
Resonance Analysis ◽  
Delayed Implantation ◽  
Size Type ◽  
The Stability ◽  
The Moment ◽  
Immediate Implantation

Abstract. This article presents the results of a clinical study of the stability and process of osteointegration implants of 11 known implant dental systems. The effect of the microstructure of 3 types of implant surface (HSTTM, SLA and RBM) and their design features (shape, size, type of carving) on the indicators of their stability and osteointegration process during immediate and delayed implantation with immediate functional load is shown and analyzed. The stability of the implants and the dynamics of the quality of osteointegration were determined by the devices «Osstell Mentor» and «Periotest» in the process of treatment, starting from the moment of implant installation in different eras (2 weeks, 1 month, 2 months and 3 months). 414 patients between the ages of 20 and 70 were monitored. Of these, there are 249 and 165 male women. The average age of the operated patients was: for men – 54 years for women – 49 years. All patients were divided into two groups of the first – 109 patients who after extraction were directly implanted into the hole of the remote tooth with the subsequent immediate load, the second group – 305 patients who were delayed implantation with immediate load. A total of 1,302 implants were installed. The study revealed a link between the type of surface of the implant, primary stability and the time of its osteointegration during certain periods of clinical observation. The results of the study demonstrated the important role of combining microstructure of the surface, design and dimension features, the type of insertion of implants on their primary stability and the process of osteointegration in the conduct of both immediate and delayed implantation. Key words: frequency resonance analysis, damping, stability, osteointegration, fixation, implants, periotestometry, immediate implantation.

Stabilisation of Aragonite: The Role of Mg2+ and Other Impurity Ions

2019 ◽  
Author(s):  
Matthew Boon ◽  
William Rickard ◽  
Andrew Rohl ◽  
Franca Jones
Keyword(s):  
Electron Backscatter Diffraction ◽  
Crystal Formation ◽  
Sulfate Ions ◽  
Inorganic Systems ◽  
Sodium Magnesium ◽  
Stable Product ◽  
The Stability ◽  
Backscatter Diffraction ◽  
First Time

Aragonite formation and stabilisation in seawater is still an area of active investigation since the thermodynamically stable product at room temperature is calcite. In this manuscript, purely inorganic systems that were found to stabilise aragonite were analysed by various techniques. Dynamic Light Scattering was used to characterise the nucleation behaviour of the system and it was found that the presence of magnesium ions during crystal formation inhibits nucleation overall, not just calcite nucleation. In addition, it was found that sulfate is not necessary to stabilise aragonite. Microanalysis by energy dispersive X-ray spectroscopy (EDS) and electron backscatter diffraction (EBSD) revealed that the aragonite that was formed had a disordered core with, sodium, magnesium and sulfate ions incorporated into the structure. To the best of the authors’ knowledge this is the first time an ACC core in aragonite has been visualised in a completely abiotic, synthetic system (in the absence of organic molecules). Inclusion of these impurities into the structure may explain the stability of aragonite in natural seawaters.

A Statistical Study of Process Variables to Optimize a High Speed Curtain Coater: Part I

TAPPI Journal ◽  
2009 ◽  
Vol 8 (1) ◽  
pp. 20-26 ◽  
Author(s):  
PEEYUSH TRIPATHI ◽  
MARGARET JOYCE ◽  
PAUL D. FLEMING ◽  
MASAHIRO SUGIHARA
Keyword(s):  
Boundary Layer ◽  
Experimental Design ◽  
High Speed ◽  
Statistical Study ◽  
Process Variables ◽  
High Speeds ◽  
The Stability ◽  
Air Removal ◽  
Removal System

Using an experimental design approach, researchers altered process parameters and material prop-erties to stabilize the curtain of a pilot curtain coater at high speeds. Part I of this paper identifies the four significant variables that influence curtain stability. The boundary layer air removal system was critical to the stability of the curtain and base sheet roughness was found to be very important. A shear thinning coating rheology and higher curtain heights improved the curtain stability at high speeds. The sizing of the base sheet affected coverage and cur-tain stability because of its effect on base sheet wettability. The role of surfactant was inconclusive. Part II of this paper will report on further optimization of curtain stability with these four variables using a D-optimal partial-facto-rial design.

Characteristics Of The Structure Formation Of Gypsum Binder Modified With Zinc Hydrosilicates

2020 ◽  
pp. 40-46
Keyword(s):  
Synergistic Effect ◽  
Physicochemical Properties ◽  
Structure Formation ◽  
Silicic Acid ◽  
Chemical Properties ◽  
Crystal Formation ◽  
Ability To Act ◽  
Chemical Factors ◽  
Sorption Characteristics

The authors' methodic for assessing the role of chemical and physic-chemical factors during the structure formation of gypsum stone is presented in the article. The methodic is also makes it possible to reveal the synergistic effect and to determine the ranges of variation of controls factors that ensure maximum values of such effect. The effect of a micro-sized modifier based on zinc hydro-silicates on the structure formation of building gypsum is analyzed and corresponding dependencies are found. It is shown that effects of influence of modifier on the properties of gypsum compositions are determined by chemical properties of modifier. Among the mentioned properties are sorption characteristics (which depend on the amount of silicic acid and its state) and physicochemical properties - the ability to act as a substrate during crystal formation. The proposed method can also be extended to other binding substances and materials. This article contributes to the understanding of the processes that occur during the structure formation of composites, which will make it possible to control the structure formation in the future, obtaining materials with a given set of properties.

PINGVINAS IR PROTĖJAS. Įsivaizdavimas kaip kitybė manyje

2007 ◽  
Vol 4 ◽  
pp. 21-37
Author(s):  
Kristupas Sabolius
Keyword(s):  
Fight Club ◽  
The World ◽  
The Moment ◽  
Hollywood Movie

Kitybės klausimas dažniausiai kyla iš ego santykio su kitais arba su pasauliu. Šiame straipsnyje daroma prielaida, kad įsivaizdavimo funkcija ištirpdo subjektą ir jame pačiame atveria intersubjektyvią perspektyvą. Šiuo tikslu sugretinami Sartre’o, Husserlio bei Merleau-Ponty įsivaizdavimo funkcijos tyrimai, kuriuose išryškėja vaizdo kaip iš ego centro išslystančios ribos statusas, ir Holivudo filmo „Kovos klubas“ siužetas. Viename iš šios juostos epizodų pasirodantis pingvinas žymi egologinės schizmos akimirką ir tampa fantazijos apsireiškimu ir įsikūnijimu.Išgryninus žaidybinį, savarankišką ir multiformišką charakterį, galime konstantuoti, kad įsivaizdavimas, jei kalbėtume Kanto terminais, yra ne papildanti tarpinė funkcija, bet transcendentalinio subjekto genezėje atlieka paradoksalų „svetimos vidujybės“ arba „vidinės svetimybės“ vaidmenį. Vaizduotė yra katalizatoriaus, kuris, likdamas šalia, įgalina transcendentalinių formų išsikristalizavimą.Pagrindiniai žodžiai: vaizduotė, įsivaizdavimas, fantazija, ego, kitybė, sąmonė.PENGUIN AND PROTEUSImagination as Otherness in meKristupas Sabolius SummaryThe question of Otherness is usually taken into account while discussing the Ego’s relation with Others as well as with the World. This article is based on the premises that the function of phantasy melts the subjectivity, revealing the perspective of intersubjectivity within it. On this purpose Sartre’s, Husserl’s and Merleau-Ponty’s researches on the function of imagination, which elucidate the image as the boundary slipping from the centre of Ego, are compared to the story of Hollywood’ movie „Fight Club“. The penguin, which appears in one of the episodes, registers the moment of egological schism, thus becoming the revelation and incarnation of phantasy. While the playful, autonomous and multiform character of imaginary is cleared out, we can ascertain, speaking in Kantian terms, that it has not a complementary or intermediary function, but, in the genesis of transcendental subject, plays the paradoxical role of „allien innerness“ or „inner alienity“. Thought remaining always beside, imagination is a catalyzer which enables crystallization of transcendental forms.Keywords: imagination, imaginary, phantasy, ego, otherness, consciousness.

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