scholarly journals A Descriptive Cohort of Suicidal Cancer Patients: Analysis of the Autopsy Case Series from 1993 to 2019 in Milan (Italy)

Author(s):  
Guendalina Gentile ◽  
Stefano Tambuzzi ◽  
Raffaella Calati ◽  
Riccardo Zoja

Suicide in cancer patients has always been a subject of clinical studies, but the contribution of forensic pathology to this phenomenon is poorly reported. With the aim of at least partially filling this gap in information, at the Institute of Forensic Medicine of Milan, Italy, we assessed all suicides that occurred in cancer patients. A descriptive and retrospective analysis was carried out by examining the database of the Institute and autopsy reports. We included 288 suicide cases with proven cancer diseases. For each suicide, sex, age, country of origin, body area affected by cancer, further pathological history, medications, previous suicide attempts and suicidal communications, as well as the place where the suicide occurred, were assessed. Furthermore, from a forensic point of view, we considered the chosen suicide method and any involved means. The majority of cases were male older adults affected by lung, colon and prostate cancer. Violent suicide methods were prevalent, and the most represented suicide method was falling from height regardless of the body area affected by cancer. Such data may be of clinical use for clinicians engaged in the front lines in order to address suicide risk prevention strategies among cancer patients.

2021 ◽  
Author(s):  
Emanuelle Garmes Pires ◽  
Gizelda Monteiro da Silva ◽  
Sonia Maria Cesar de Azevedo Silva

Abstract Background: Near-fatal suicide attempts by poisoning increase the risk of subsequent suicide and results in hospitalizations due to health damage caused by chemical agents. There have been no studies in Brazil considering the factors related to the choice of self-poisoning in near-fatal suicide attempts and individual awareness of hazards if non-lethal outcome. Aims: Investigate the factors influencing the decision to use poisoning in near-fatal suicide attempts and the perception of its dangers in case of survival. Method: Exploratory qualitative research with 17 adult patients who had near-fatal suicide attempts by self-poisoning hospitalized at a general hospital in São Paulo, Brazil. Results: Patients reported three main reasons for the choice of method: the expectation of death without suffering, the belief of its efficacy as a suicide method, and ease of access to chemical agents. None considered the health risks associated with the chemical agents if they survived due to impulsivity and misinformation. Conclusion: Most participants chose self-poisoning with the expectation of death without suffering. Importantly, although half the sample required hospitalization, none had considered the risks associated with the use of such chemical agents. We conclude that prevention strategies should inform the possible health damages related to the use of chemical agents for people at risk of suicide.


Crisis ◽  
2013 ◽  
Vol 34 (5) ◽  
pp. 335-347 ◽  
Author(s):  
Adrienne Rivlin ◽  
Robert Ferris ◽  
Lisa Marzano ◽  
Seena Fazel ◽  
Keith Hawton

Background: Prisoners are at high risk of suicide. Aims: This study aimed to develop a typology of prison suicide. Method: We interviewed 60 male prisoners who made near-lethal suicide attempts in prison to obtain quantitative and qualitative data regarding psychiatric, psychological, social, and criminological factors. We analyzed this information to develop a typology to classify suicidal prisoners and validated it by having a prison psychiatrist independently rate each interview transcript. Results: We developed a typology of five subgroups: attempts that (1) were due to a prisoner being unable to cope in prison, (2) were motivated by psychotic symptoms, (3) had instrumental motives, (4) were ”unexpected” by the prisoners themselves, and (5) were associated with withdrawal from drugs. The interrater reliability as measured by Cohen’s was good to excellent at 0.81 (p < .001), 95% CI (0.69, 0.93). Conclusion: With further validation in other samples, this typology may assist suicide prevention initiatives in prisons as well as other forensic institutions by informing the assessment and formulation of suicide risk.


2019 ◽  
Vol 15 (3) ◽  
pp. 637-649
Author(s):  
Giedre Bulotiene ◽  
Kamile Pociute

The suicide risk of people diagnosed with cancer is two times higher than the general population. The number of cases of diagnosed cancer is estimated to rise by 70% over the next two decades. Evidence-based prevention strategies are necessary to protect this vulnerable group of individuals. The purpose of this review was to find out the risk factors of suicide and which types of interventions can serve as prevention strategies. Psychosocial interventions, pharmacotherapy and physical activity can play a preventive role in reducing psychosocial and physical risk factors, such as mental disorders, poor social support, poor performance status and pain. Further research is needed to develop effective suicide prevention strategies for cancer patients.


2020 ◽  
Vol 98 (4) ◽  
pp. 131-134
Author(s):  
I.R. Gilmutdinova ◽  
P.S. Eremin

Introduction. Oncological diseases take the second place in the world in mortality rate after cardiovascular pathology. The development of the tumor is accompanied by the appearance and accumulation of a number of pathological metabolites. At the same time, it is worth noting that the expansion of indications for the use of surgical methods of treatment, as well as an increase in the range of medicated antitumor drugs, especially against the background of combination therapy, is still accompanied by aggressive effects on the patient's body. Thus, the consequences of radiation and chemotherapy are quite significant and consist of the cumulation of cytotoxic drugs that are toxic not only for tumor cells, but also for other tissue structures of the body. In this connection, intensive therapy of endogenous intoxication in case of tumor lesions is one of the complex interdisciplinary problems, in which should participate surgeons, resuscitators, pathophysiologists, transfusiologists. Purpose. Analysis of literature data on the use of plasmapheresis as an effective component of rehabilitation measures from the point of view of pathophysiology in cancer patients. Conclusion. Considering the possibility of using extracorporeal detoxification methods in the treatment and rehabilitation of cancer patients, it should be noted that, against the background of chemotherapy and / or radiation therapy, plasmapheresis is one of the most common indications for use. Positive responses after plasmapheresis have been reported in patients with carcinoma of the lung, colon and breast. In addition, there are reports of the effectiveness of the method in patients with melanoma, head and neck tumors, lymphomas, leukemia and Kaposi’s sarcoma with acquired immunodeficiency. However, there is currently a limited number of studies aimed at the effectiveness of the use of extracorporeal detoxification in the complex treatment of cancer patients.


Crisis ◽  
2002 ◽  
Vol 23 (1) ◽  
pp. 3-10 ◽  
Author(s):  
Mustafa Bilici ◽  
Mehmet Bekaroğlu ◽  
Çiçek Hocaoğlu ◽  
Serhat Gürp&inodot;nar ◽  
Cengiz Soylu ◽  
...  

Summary: Objective: Studies of completed and attempted suicide in Turkey are based on data of State Institute of Statistics (SIS) and emergency clinics of the large hospitals. This study seeks (1) to find, independent of the SIS and hospital data, the annual incidences of completed and attempted suicide in Trabzon, Turkey; (2) to examine the associated factors between the incidence of completed and attempted suicide. Method: The data are derived by using a method specially designed for this study. Data sources include emergency clinics in all hospitals, village clinics, the Forensic Medical Center of Trabzon, the Governorship of Trabzon, “mukhtars” (local village representatives) of neighborhoods, the Office of the Public Prosecutor of Trabzon, the Police Headquarters and Gendarmerie, and the local press organs. Results: The incidences of completed and attempted suicide per 100,000 inhabitants turned out to be 2.60 and 31.5, respectively, whereas the SIS reported the incidence of completed suicide to be 1.11 per 100,000 inhabitants in Trabzon in 1995. Conclusion: Our results demonstrate that SIS data are inadequate for suicide research in Turkey. Our findings show that the risk of completed and attempted suicide is high in young, unmarried, and unemployed persons, and that these groups must be carefully evaluated for suicide risk. The study highlights the need for culture-specific research on suicidal behavior in Turkey.


1996 ◽  
Vol 75 (02) ◽  
pp. 368-371 ◽  
Author(s):  
T Barbul ◽  
G Finazzi ◽  
A Grassi ◽  
R Marchioli

SummaryHematopoietic colony-stimulating factors (CSFs) are largely used in patients with cancer undergoing cytotoxic treatment to accelerate neutrophil recovery and decrease the incidence of febrile neutropenia. Clinical practice guidelines for their use have been recently established (1), taking into account clinical benefit, but also cost and toxicity. Vascular occlusions have been recently reported among the severe reactions associated with the use of CSFs, in anedoctal case reports (2, 3), consecutive case series (4) and randomized clinical trial (5, 6). However, the role of CSFs in the pathogenesis of thrombotic complications is difficult to ascertain, because pertinent data are scanty and widely distributed over a number of heterogenous investigations. We report here a systematic review of relevant articles, with the aims to estimate the prevalence of thrombosis associated with the use of CSFs and to assess if this rate is significantly higher than that observed in cancer patients not receiving CSFs.


Author(s):  
Evi Zohar

Continuing the workshop I've given in the WPC Paris (2017), this article elaborates my discussion of the way I interlace Focusing with Differentiation Based Couples Therapy (Megged, 2017) under the systemic view, in order to facilitate processes of change and healing in working with intimate couples. This article presents the theory and rationale of integrating Differentiation (Bowen, 1978; Schnarch, 2009; Megged, 2017) and Focusing (Gendlin, 1981) approaches, and its therapeutic potential in couple's therapy. It is written from the point of view of a practicing professional in order to illustrate the experiential nature and dynamics of the suggested therapeutic path. Differentiation is a key to mutuality. It offers a solution to the central struggle of any long term intimate relationship: balancing two basic life forces - the drive for individuality and the drive for togetherness (Schnarch, 2009). Focusing is a body-oriented process of self-awareness and emotional healing, in which one learns to pay attention to the body and the ‘Felt Sense’, in order to unfold the implicit, keep it in motion at the precise pace it needs for carrying the next step forward (Gendlin, 1996). Combining Focusing and Differentiation perspectives can cultivate the kind of relationship where a conflict can be constructively and successfully held in the inner world of each partner, while taking into consideration the others' well-being. This creates the possibility for two people to build a mutual emotional field, open to changes, permeable and resilient.


2020 ◽  
Vol 26 (18) ◽  
pp. 2073-2086
Author(s):  
Saule Balmagambetova ◽  
Andrea Tinelli ◽  
Ospan A. Mynbaev ◽  
Arip Koyshybaev ◽  
Olzhas Urazayev ◽  
...  

High-risk human papillomavirus strains are widely known to be the causative agents responsible for cervical cancer development. Aggregated damage caused by papillomaviruses solely is estimated in at least 5% of all malignancies of the human body and 16% in cancers that affect the female genital area. Enhanced understanding of the complex issue on how the high extent of carcinogenicity is eventually formed due to the infection by the Papoviridae family would contribute to enhancing current prevention strategies not only towards cervical cancer, but also other HPV associated cancers. This review article is aimed at presenting the key points in two directions: the current cervical cancer prevention and related aspects of HPV behavior. Virtually all applied technologies related to HPV diagnostics and screening programs, such as HPV tests, colposcopy-based tests (VIA/VILI), conventional and liquid-based cytology, currently available are presented. Issues of availability, advantages, and drawbacks of the screening programs, as well as vaccination strategies, are also reviewed in the article based on the analyzed sources. The current point of view regarding HPV is discussed with emphasis on the most problematic aspect of the HPV family concerning the observed increasing number of highly carcinogenic types. Present trends in HPV infection diagnostics throughout the human fluids and tissues are also reported, including the latest novelties in this field, such as HPV assay/self-sample device combinations. Besides, a brief outline of the related prevention issues in Kazakhstan, the leading country of Central Asia, is presented. Kazakhstan, as one of the post-soviet middle-income countries, may serve as an example of the current situation in those terrains, concerning the implementation of globally accepted cervical cancer prevention strategies. Along with positive achievements, such as the development of a nationwide screening program, a range of drawbacks is also analyzed and discussed.


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